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showing 10 items of 2078 documents
Is hard physical work in the early working life associated with back pain later in life? A cross-sectional study among 5700 older workers
2020
ObjectivesPhysically demanding work increases the risk of developing musculoskeletal disorders during working life, with low back pain (LBP) as the most prevalent and debilitating musculoskeletal disorder worldwide. However, a lack of knowledge exists about the role of early working years on musculoskeletal health later in life. This study investigated whether an exposure–response association exists between physical demands in early working life and risk of LBP in later working life.DesignCross-sectional study.Setting, participants and outcome measureIn the SeniorWorkingLife study, 5909 wage earners aged ≥50 years with currently sedentary work replied to a questionnaire survey in 2018 about…
Centenarian offspring: A model for understanding longevity
2013
Abstract: A main objective of current medical research is to improve the life quality of elderly people as priority of the continuous increase of ageing population. This phenomenon implies several medical, economic and social problems because of dramatic increase in number of non autonomous individuals affected by various pathologies. Accordingly, the research interest is focused on understanding the biological mechanisms involved in determining the positive ageing phenotype, i.e. the centenarian phenotype. In achieving this goal the choice of an appropriate study models is fundamental. Centenarians have been used as an optimal model for successful ageing. However, this model shows several …
Niveles de Salud Psicosocial en función del Nivel de Experiencia en Residencias [Psychosocial health levels depending on experience in workers in res…
2015
Scientific literature has paid little attention to the direct care staff residences for people with disabilities. However, their workload is considerable and it has higher risk of stress than other social service workers. The main objective of this study is to analyze the relationships between experience and the psychosocial health levels in workers who look after people with disabilities in residences. A transversal study with 100 participants was made. Results show that workers who are working more time in residences with disable people have lower levels in some health variables (hypertension, headache, back pain, stomachache, GHQ-total and GHQ-depression) and in psychosocial variables (e…
Lysine synthesis control in Corynebacterium glutamicum RC 115 in mixed substrate (glucose-acetate) medium.
2003
The effect of acetate as a glucose co-substrate on growth, lysine synthesis and experimental lysine yield from carbon substrates by Corynebacterium glutamicum RC 115 was investigated. It was found that low amounts of acetate, injected with a glucose-acetate pulse into the steady-state continuous culture in bioreactor, caused a slight decrease in the specific rates of glucose uptake and bacterial growth, but a significant increase in the cell specific rate of lysine synthesis and an increase in lysine yield. In contrast, acetate injected in high amounts was followed by a drastic decrease in the values of these parameters. A strong increase in experimental lysine yield under the latter condit…
Msb2 is a Ste11 membrane concentrator required for full activation of the HOG pathway.
2015
The high osmolarity glycerol (HOG) pathway, composed of membrane-associated osmosensors, adaptor proteins and core signaling kinases, is essential for the survival of yeast cells under hyper-osmotic stress. Here, we studied how the MAPKKK Ste11 might change its protein interaction profile during acute stress exposure, with an emphasis on the sensory system of the so-called Sho1/Msb2 signaling branch. To characterize the transience of protein-protein interactions we utilized a recently described enzymatic in vivo protein proximity assay (M-track). Accordingly, interaction signals between Ste11 and many of its signaling partners can already be detected even under basal conditions. In most cas…
ARQ Aware Scheduling for the IEEE 802.16 Base Station
2008
The IEEE 802.16 technology defines the ARQ mechanism that enables a connection to resend data at the MAC level if an error is detected. In this paper, we analyze the ARQ aware scheduling for the 802.16 base station. In particular, we consider how the BS scheduler can account for the ARQ block size, absence of the ARQ block rearrangement, and the ARQ transmission window. We propose a set of constraints that can be applied to any base station scheduler algorithm. To test them, we run a number of simulation scenarios. The simulations results confirm that the ARQ aware scheduling can improve the overall performance.
Performance analysis of the ieee 802.16 arq mechanism
2007
The IEEE 802.16 technology defines the ARQ mechanism that enables a connection to resend data at the MAC level if an error is detected. In this paper, we analyze the key features and parameters of the 802.16 ARQ mechanism. In particular, we consider a choice for the ARQ feedback type, an algorithm to build block sequences, a scheduling of the ARQ feedbacks and retransmissions, the ARQ block rearrangement, ARQ transmission window and ARQ block size. We run a number of simulation scenarios to study these parameters and how they impact a performance of application protocols. The simulation results reveal that the ARQ mechanism and its correct configuration play an important role in transmittin…
On ARQ feedback intensity of the IEEE 802.16 ARQ mechanism
2008
The IEEE 802.16 standard defines the ARQ mechanism as a part of the MAC layer. The functioning of the ARQ mechanism depends on a number of parameters. The IEEE 802.16 specification defines them but it does not provide concrete values and solutions. We ran simulation scenarios to study how the ARQ feedback intensity impacts the performance of application protocols. The simulation results reveal that a low ARQ feedback intensity results only in a marginal improvement. Though it is possible to optimize the ARQ feedback intensity, it is reasonable to rely upon more frequent ARQ feedback messages as they do not result in a performance degradation. At the same time, ARQ connections, which work on…
Ca. 750–1100 Ma magmatic events and Grenville-age deformation in Sri Lanka: relevance for Rodinia supercontinent formation and dispersal, and Gondwan…
2003
Abstract Large volumes of ∼880–1100 Ma calc-alkaline granitoid rocks in the Wanni and Vijayan crustal provinces of Sri Lanka make it likely that these domains were produced in active margin settings, probably Grenville-age magmatic arcs. We report new single zircon evaporation ages and Nd isotopic systematics for dioritic to granodioritic gneisses of the Kadugannawa Complex of central Sri Lanka which record a period of magmatic arc activity between 1006 and 881 Ma and show this complex to be part of the Wanni domain. Both provinces were probably generated in arc-related settings at the outer margin of Rodinia, but this cannot be ultimately proven on the basis of the currently available data…
Filtering Real World Networks: A Correlation Analysis of Statistical Backbone Techniques
2023
Networks are an invaluable tool for representing and understanding complex systems. They offer a wide range of applications, including identifying crucial nodes, uncovering communities, and exploring network formation. However, when dealing with large networks, the computational challenge can be overwhelming. Fortunately, researchers have developed several techniques to address this issue by reducing network size while preserving its fundamental properties [1-9]. To achieve this goal, two main approaches have emerged: structural and statistical methods. Structural methods aim to keep a set of topological features of the network while reducing its size. In contrast, statistical methods elimi…