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Effects of a Feedback-Demanding Stroke Clock on Acute Stroke Management: A Randomized Study.

2023

Background and Purpose: This randomized study aimed to evaluate whether the use of a stroke clock demanding active feedback from the stroke physician accelerates acute stroke management. Methods: For this randomized controlled study, a large-display alarm clock was installed in the computed tomography room, where admission, diagnostic work-up, and intravenous thrombolysis occurred. Alarms were set at the following target times after admission: (1) 15 minutes (neurological examination completed); (2) 25 minutes (computed tomography scanning and international normalized ratio determination by point-of-care laboratory completed); and (3) 30 minutes (intravenous thrombolysis started). The resp…

Malemedicine.medical_specialtythrombolysisTime FactorsComputed Tomography Angiographymedicine.medical_treatment610law.inventionBrain IschemiaFeedbackPhysical medicine and rehabilitationRandomized controlled trialFibrinolytic AgentslawmedicineHumansActive feedbackThrombolytic TherapyAcute managementStrokeAcute strokeAgedAdvanced and Specialized NursingAged 80 and overbusiness.industryDisease ManagementThrombolysisMiddle Agedmedicine.diseaseStrokethrombectomyTissue Plasminogen ActivatorFemaleNeurology (clinical)Cardiology and Cardiovascular Medicinebusinessacute managementTomography X-Ray ComputedStroke
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Development of comorbidity-adapted exercise protocols for patients with knee osteoarthritis

2014

Mariëtte de Rooij,1 Marike van der Leeden,1,2 Ellis Avezaat,3 Arja Häkkinen,4 Rob Klaver,1 Tjieu Maas,5 Wilfred F Peter,1 Leo D Roorda,1 Willem F Lems,1,6 Joost Dekker1,71Amsterdam Rehabilitation Research Center, Reade, Amsterdam, the Netherlands; 2VU University Medical Center Department of Rehabilitation Medicine, Amsterdam, the Netherlands; 3Sint Lucas Andreas Hospital, Department of Physical Therapy, Amsterdam, the Netherlands; 4Department of Health Sciences, University of Jyväskylä and Jyväskylä Central Hospital, Jyväskylä, Finland; 5HAN University, Institute of Health, GGM, Institute for Sports and Exercise Studies…

Malemedicine.medical_treatmentOsteoarthritislaw.inventionPulmonary Disease Chronic ObstructiveRandomized controlled triallawActivities of Daily LivingOrthopedics and Sports MedicineniveltulehdusHearing DisordersDepression (differential diagnoses)Original Researchkomorbiditeettiexercise therapyRehabilitationDepressionta3141General MedicineMiddle AgedOsteoarthritis KneeLow back paincomorbidityTreatment Outcomearthritiscoexisting diseaseHypertensionFemaleChronic Painmedicine.symptomliikuntahoitomedicine.medical_specialtyHeart DiseasesVision DisordersBiomedical Engineeringknee osteoarthritisrehabilitationRheumatologymental disordersmedicineHumansObesityAgedProtocol (science)business.industryRC952-954.6medicine.diseaseComorbidityDiabetes Mellitus Type 2GeriatricsHeart failureClinical Interventions in AgingQuality of LifePhysical therapykuntoutusGeriatrics and GerontologybusinessLow Back PainClinical Interventions in Aging
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Low back pain during military service predicts low back pain later in life

2016

The aim of the present study was to assess associations between physician diagnosed unspecified low back pain (LBP) during compulsory military service and self-reported LBP and physical fitness measured on average four years after military service. From a total of 1155 persons who had been pass medical examination for military service and who had completed physically demanding military training between 1997 and 2007, 778 men participated in a refresher military training course and physical tests. In this study, the association between LBP during military service and LBP in later life in addition to the association between LBP and physical fitness were examined. A total of 219 out of 778 par…

Malemilitary serivicesMedical DoctorsHealth Care ProvidersPhysical fitnesslcsh:MedicineMusculoskeletal symptomPathology and Laboratory Medicine0302 clinical medicineRisk FactorsMedicine and Health SciencesComputingMilieux_COMPUTERSANDEDUCATIONEthnicitiesPublic and Occupational Health030212 general & internal medicinelcsh:Scienceta315Musculoskeletal Systemlow back painMultidisciplinarypathological conditions signs and symptomspuolustusvoimatLow back painProfessionsMilitary personnelMilitary PersonnelLegsselkäpopulation characteristicsAnatomymedicine.symptomBehavioral and Social Aspects of HealthResearch ArticleAdultmedicine.medical_specialtyAdolescentMilitary serviceLower Back PainKirurgia anestesiologia tehohoito radiologia - Surgery anesthesiology intensive care radiologyPainback pain03 medical and health sciencesSigns and SymptomsDiagnostic MedicineselkäsairaudetPhysicianshealth services administrationIntensive careAnesthesiologymedicineHumansRisk factorbusiness.industryLimbs (Anatomy)lcsh:RBiology and Life ScienceskipuPhysical Activitynervous system diseasesHealth Carebody regionsPhysical FitnessPeople and PlacesPhysical therapyPopulation Groupingslcsh:QbusinessFinns030217 neurology & neurosurgeryFollow-Up StudiesPLOS ONE
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Effects and underlying mechanisms of unstable shoes on chronic low back pain : a randomized controlled trial

2018

Este artículo se encuentra disponible en la página web de la revista en la siguiente URL: https://journals.sagepub.com/doi/abs/10.1177/0269215517753972?rfr_dat=cr_pub%3Dpubmed&url_ver=Z39.88-2003&rfr_id=ori%3Arid%3Acrossref.org&journalCode=crea Este es el postprint del siguiente artículo: Lisón, JF., Ortega-Santana, B., Antón-Nogués, Á., González-Requena, P., Vera-Hervás, C., Doménech-Fernández, J. et al. (2018). Effects and underlying mechanisms of unstable shoes on chronic low back pain : a randomized controlled trial. Clinical Rehabilitationol. 32, n. 5 (may), pp. 654-662, que se ha publicado de forma definitiva en https://doi.org/10.1177/0269215517753972 This is the pre-peer reviewed ve…

Malemusculoskeletal diseasesmedicine.medical_specialtyPhysical Therapy Sports Therapy and RehabilitationElectromyographylaw.invention03 medical and health sciencesDisability Evaluation0302 clinical medicineRandomized controlled triallawmedicineHumansIn patientRange of Motion ArticularBackache - Treatment.Spine - Electromyography.Abdominal MusclesChronic pain - Treatment.Lumbar Vertebraemedicine.diagnostic_testbusiness.industryElectromyographyBack MusclesRehabilitation030229 sport sciencesMiddle AgedGaitChronic low back painShoesDolor crónico - Tratamiento.Lumbago - Tratamiento.Orthopedic surgeryPhysical therapyColumna vertebral - Electromiografía.Lumbar spineFemaleChronic PainRange of motionbusinessLow Back Pain030217 neurology & neurosurgery
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Muscle Activity Adaptations to Spinal Tissue Creep in the Presence of Muscle Fatigue.

2016

Aim The aim of this study was to identify adaptations in muscle activity distribution to spinal tissue creep in presence of muscle fatigue. Methods Twenty-three healthy participants performed a fatigue task before and after 30 minutes of passive spinal tissue deformation in flexion. Right and left erector spinae activity was recorded using large-arrays surface electromyography (EMG). To characterize muscle activity distribution, dispersion was used. During the fatigue task, EMG amplitude root mean square (RMS), median frequency and dispersion in x- and y-axis were compared before and after spinal creep. Results Important fatigue-related changes in EMG median frequency were observed during m…

Malemyalgialcsh:MedicineElectromyographyPathology and Laboratory MedicineMaterial Fatigue0302 clinical medicineMaterials PhysicsMedicine and Health SciencesRange of Motion Articularlcsh:ScienceMusculoskeletal SystemFatigueMultidisciplinarymedicine.diagnostic_testPhysicsClassical MechanicsAnatomyDeformationBioassays and Physiological Analysismedicine.anatomical_structureCreepMuscle FatiguePhysical SciencesMetallurgyCardiologyFemaleAnatomymedicine.symptomRange of motionAlgorithmsMuscle ElectrophysiologyMuscle ContractionResearch ArticleMuscle contractionAdultMetal FatigueMuscle tissuemedicine.medical_specialtyMaterials sciencePostureMaterials ScienceMuscle TissueResearch and Analysis MethodsYoung Adult03 medical and health sciencesSigns and SymptomsInternal medicinemedicineHumansPain ManagementMuscle SkeletalElectrodesMuscle contractureBackDamage MechanicsMuscle fatigueElectromyographyElectrophysiological Techniqueslcsh:RBiology and Life SciencesMyalgia030229 sport sciencesSpineBiological Tissuelcsh:Q030217 neurology & neurosurgeryPLoS ONE
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Lifestyle Risk Factors Increase the Risk of Hospitalization for Sciatica: Findings of Four Prospective Cohort Studies

2017

BACKGROUND: The purpose of this study is to assess the effects of lifestyle risk factors on the risk of hospitalization for sciatica and to determine whether overweight or obesity modifies the effect of leisure-time physical activity on hospitalization for sciatica. METHODS: We included 4 Finnish prospective cohort studies (Health 2000 Survey, Mobile Clinic Survey, Helsinki Health Study, and Young Finns Study) consisting of 34,589 participants and 1259 hospitalizations for sciatica during 12 to 30 years of follow-up. Sciatica was based on hospital discharge register data. We conducted a random-effects individual participant data meta-analysis. RESULTS: After adjustment for confounding facto…

Maleobesityphysical activityliikuntaOverweightCohort Studies0302 clinical medicineRisk FactorsEpidemiologyMedicineProspective Studies030212 general & internal medicineta315Prospective cohort studylow back painAged 80 and over2. Zero hungereducation.field_of_studyexerciseta3141ylipainoASSOCIATIONGeneral MedicineMiddle AgedDEGENERATION3. Good healthLUMBAR DISC DISEASEFemaleSMOKING MODELmedicine.symptomRisk assessmentLumbar disc diseaseLOW-BACK-PAINhospitalizationCohort studyAdultmusculoskeletal diseasesmedicine.medical_specialtyPopulationiskiassmokingYoung Adult03 medical and health sciencestupakointiInternal medicineHumanseducationLife StyleMETAANALYSISAgedsciatica030203 arthritis & rheumatologybusiness.industryta3121Overweightmedicine.diseasenervous system diseases3141 Health care sciencePHYSICAL-ACTIVITYINTERVERTEBRAL DISCSPhysical therapylihavuusFOLLOW-UPbusinessBody mass indexThe American Journal of Medicine
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Cross-sectional associations between the diversity of sport activities and the type of low back pain in adulthood

2020

Leisure-time physical activity has a complex relationship with low back pain (LBP). Thus, we aimed to investigate whether the diversity of sport activities is associated with the type of LBP. In the FinnTwin16 study, 4246 (55% females) Finnish twins at mean age 34.1 years replied to a health behaviour survey in 2010-2012. Based on the participation in different sport activities, we created two measures of diversity: quantity (i.e. the number of sport activities: 1, 2, 3, 4 and >= 5) and quality (i.e. the type of sport activity: endurance, strength, body care, etc.). Based on the frequency, duration and type of LBP, we created three groups: no history of LBP lasting more than one day, radiat…

Malephysical activitylumbagoliikuntaLogistic regressionRunning0302 clinical medicineOdds RatioOrthopedics and Sports Medicinekohorttitutkimuslow back painexerciseConfoundingGeneral MedicineLow back pain3142 Public health care science environmental and occupational healthPREVALENCEpopulation characteristicsselkäFemalemedicine.symptomCohort studyfyysinen aktiivisuusSportsCohort studyAdultmedicine.medical_specialtyPhysical activity030209 endocrinology & metabolismPhysical Therapy Sports Therapy and Rehabilitationiskias03 medical and health sciencesSex FactorsDiseases in Twinsmedicinecohort studyHumanssciaticabusiness.industryDISABILITYHealth behaviourkipu030229 sport sciencesOdds ratioBicyclingnervous system diseasesLogistic ModelsPHYSICAL-ACTIVITYPhysical EndurancePhysical therapybusinesshuman activitiesDiversity (business)
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The prevalence of musculoskeletal disorders and low back pain among Italian nurses. An observationalstudy

2020

Background and aim of the work: Musculoskeletal disorders and low back pain have negative impact amongst Italian nurses who work in hospital. Nursing staff are known to be at risk of developing back disorders, where low back pain has a prevalence from 16% to 60% in the world. This study aims to determine the prevalence of musculoskeletal disorders and low back pain among nurses who working in a Roman hospital. Methods: Cross sectional study was carried out in an Italian hospital and the Nordic Musculoskeletal Questionnaire-IRSST was administered to 256 registered nurses. Logistic regression analyses were performed to understand risk factors associated with pain. Results: Nurses reported dif…

MaleprevalencenurseNursesOriginal Article: Healthcare Professionals: Physical and Psychological ConditionsSettore MED/45 - Scienze Infermieristiche Generali Cliniche E PediatricheOccupational DiseasesCross-Sectional StudiesnursingSurveys and QuestionnairesitalyHumansrisk factorsFemaleitaly; low back pain; musculoskeletal disorder; nurse; prevalence; risk factorsmusculoskeletal disorderMusculoskeletal Diseaseslow back pain
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Pan-cancer analysis of whole genomes

2020

Publisher's version (útgefin grein)

Maletert promoter mutationsCancer development and immune defence Radboud Institute for Molecular Life Sciences [Radboudumc 2]DNA Mutational AnalysisNormal tissuesystematic analysisGermlineTranscriptome0302 clinical medicineAetiologyCàncerCellular SenescenceCancer0303 health sciencesdna-damageMassive parallel sequencingPan cancerREARRANGEMENTSHigh-Throughput Nucleotide SequencingGenomicsSciences bio-médicales et agricolesTelomereCOMPREHENSIVE3. Good healthTERT PROMOTER MUTATIONSsignatures030220 oncology & carcinogenesisScience & Technology - Other TopicsErfðarannsóknirHuman:Informàtica::Aplicacions de la informàtica::Bioinformàtica [Àrees temàtiques de la UPC]EvolutionRNA SplicingGenomicsArticleEvolution MolecularStructural variationRC025403 medical and health sciencesSDG 3 - Good Health and Well-beingGeneticgenomicsSYSTEMATIC ANALYSISGeneticsGenomics--Databases.HumansGenetic TestingMolecular BiologySIGNATURESWhole genome sequencing1000 MultidisciplinaryChromothripsisScience & TechnologyRC0254 Neoplasms. Tumors. Oncology (including Cancer)Information DisseminationResearchInstitutes_Networks_Beacons/mcrcPreventionBiology and Life SciencesMolecularOncogenesCloud Computingmedicine.diseaseGenòmicaCompute cloudsMutation570 Life sciences; biologyCOMPREHENSIVE CHARACTERIZATIONGenèticaWhole Genome Sequencing--methodsBackground informationDNA Mutational Analysis ; Evolution ; Genetic / genetics ; Genome ; Genomics ; Germ-Line Mutation / genetics ; High-Throughput Nucleotide Sequencing ; Human / genetics ; Humans ; ICGC/TCGA Pan-Cancer Analysis of Whole Genomes ConsortiumMedizinGenomeWhole-genomeGenome mappingNeoplasms2.1 Biological and endogenous factorsPromoter Regions GeneticCàncer -- Aspectes genèticsTelomeraseGeneticsWomen's cancers Radboud Institute for Molecular Life Sciences [Radboudumc 17]MultidisciplinaryChromothripsisGenomeManchester Cancer Research Centregenomics cancer profiling3rd-DAS10124 Institute of Molecular Life SciencesWomen's cancers Radboud Institute for Health Sciences [Radboudumc 17]Multidisciplinary SciencesParallel sequencingICGC/TCGA Pan-Cancer Analysis of Whole Genomes ConsortiumFemaleprofilingMedical GeneticsEngineering sciences. TechnologyBiotechnologyGeneral Science & TechnologyThe Cancer Genome Atlas610 Medicine & healthComputational biologyQH426 GeneticsBiologyConsortium of the International Cancer Genome ConsortiumPromoter RegionsGermline mutationPan-cancer analysisKrabbameinsrannsóknirmedicinecancerddc:610QH426Germ-Line MutationMedicinsk genetikKrabbamein030304 developmental biologyCell ProliferationLANDSCAPEGenome Humancomprehensive characterizationPan-cancer analysis of whole genomesPoint mutationHuman GenomeCancerReproducibility of ResultsSOMATIC MUTATIONSEVOLUTIONCancer sequencing Chromothripsis telomereDNA-DAMAGEMutagenesisPATTERNS3111 BiomedicineCHARACTERIZATION
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Incidence and risk factors for back pain in young floorball and basketball players : A prospective study

2018

The aim of this study was to investigate the incidence of back pain in young basketball and floorball players under 21 years of age. The secondary aim was to examine risk factors especially for low back pain (LBP). Nine basketball and nine floorball teams (n = 396) participated in this prospective follow‐up study (2011‐2014). Young athletes (mean age 15.8 ± 1.9) performed physical tests and completed a questionnaire at baseline. The follow‐up lasted 1‐3 years per player. During the follow‐up, back pain reported by the players was registered on a weekly basis and verified by a study physician. The exposure time (AE) on team practices and games was recorded by the coach. Altogether back pain …

Maleyouth athlete0302 clinical medicinenuoretRisk FactorsBack painOrthopedics and Sports MedicineProspective Studies030212 general & internal medicineRange of Motion ArticularProspective cohort studyta315Finlandsports injuriesurheiluvammatbiologyIncidencespinal painLow back painLower Extremityselkäback injuryFemaleIliopsoasmedicine.symptomteam sportsselkäydinJoint hypermobilitysports injurymedicine.medical_specialtyBasketballAdolescentPhysical Therapy Sports Therapy and RehabilitationBasketballyoung peopleBack injury03 medical and health sciencesselkärankajoukkueet (urheilu)medicineHumansjoukkueurheiluMuscle StrengthAthletesbusiness.industrykipu030229 sport sciencesbiology.organism_classificationmedicine.diseaseathletesPhysical therapybusinessLow Back Painhuman activitiesFollow-Up StudiesurheilijatScandinavian Journal of Medicine and Science in Sports
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