Search results for "basel"
showing 10 items of 332 documents
Triple therapy de-escalation to dual bronchodilation in COPD patients: Baseline data from the DACCORD cohort
2020
Background: GOLD recommends triple therapy only in COPD patients with frequent exacerbations despite long-acting bronchodilators who exhibit a high blood eosinophil level (≥300/μL). Indication for ICS containing therapy should be reassessed regularly. Methods: The German real life study DACCORD included COPD patients who had received free triple therapy for ≥ 6 months prior to study entry. At baseline, patients were switched to LABA+LAMA fixed-dose combination (FDC) or maintained triple therapy upon discretion of the treating physician. Here, we compare baseline data of the 2 groups. Results: 1182 patients were recruited into DACCORD of which 30.7% were moved to LABA+LAMA FDC. Patients in t…
Benefits of tiotropium/olodaterol compared with tiotropium in patients receiving COPD LAMA at baseline: pooled analysis of 4 clinical trials
2020
Cancer and Infective Endocarditis: Characteristics and Prognostic Impact
2021
Background: The interplay between cancer and IE has become of increasing interest. This study sought to assess the prevalence, baseline characteristics, management, and outcomes of IE cancer patients in the ESC EORP EURO-ENDO registry.Methods: Three thousand and eighty-five patients with IE were identified based on the ESC 2015 criteria. Three hundred and fifty-nine (11.6%) IE cancer patients were compared to 2,726 (88.4%) cancer-free IE patients.Results: In cancer patients, IE was mostly community-acquired (74.8%). The most frequently identified microorganisms were S. aureus (25.4%) and Enterococci (23.8%). The most frequent complications were acute renal failure (25.9%), embolic events (2…
Baseline data from a prospective international disease registry for Niemann-Pick disease type C
2011
C0307 Baseline characteristics and management of patients with splanchnic vein thrombosis: Results of an international registry
2012
Dental caries in Mexican schoolchildren : a comparison of 1988?1989 and 1998?2001 surveys
2012
Objectives: To compare two surveys across seven states for the prevalence of dental caries among Mexican schoolchildren. Study Design: Analysis of two cross-sectional surveys: Schoolchildren from 6 to 10 years of age were examined in the 1988–1989 survey and 6- to 10-year-old and 12-year-old students were included in the 1998–2001 survey. The baseline data of seven states were available for analysis. Representative probability samples were conducted statewide in both surveys. The World Health Organization (WHO) method was used to obtain the dental caries index (dmft, DMFT). At present, additional and more recent epidemiological data representative statewide in Mexico are unavailable. Result…
Do overactive bladder symptoms and their treatment-associated changes exhibit a normal distribution? Implications for analysis and reporting
2020
Aims: To explore the use of means vs medians (assuming or not the presence of normal distribution) in studies reporting overactive bladder syndrome symptoms and to test for normal distribution of basal values and treatment-associated changes thereof in two large noninterventional studies. Methods: Systematic review of all original studies reporting on at least one overactive bladder syndrome symptom published in four leading urology journals in 2016 to 2017. Testing of the normal distribution of urgency, incontinence, frequency, and nocturia in two large noninterventional studies (n = 1335 and 745). Results: Among 48 eligible articles, 86% reported means (assuming a normal distribution), 6%…
Reactive Response and Adaptive Modifications in Dynamic Stability to Changes in Lower Limb Dynamics in the Elderly while Walking
2011
The aim of this study was to examine the reactive responses and adaptive modifications in dynamic stability resulting from a unilateral change in lower limb dynamics in older and younger adults while walking. Eleven older (62- 76yrs) and eleven younger (22-30yrs) subjects walked on a treadmill and performed different gait conditions using an external resistance against lower limb movement. The margin of stability (MoS) at touchdown was calculated as the difference between base of support (BoS) and extrapolated centre of mass. After the resistance was turned on unexpectedly, older adults needed more steps to get back to the MoS baseline level due to a lower increase of the BoS. In the follow…