Search results for "basi"
showing 10 items of 12854 documents
Advances in immunopathogenesis of macrophage activation syndrome during rheumatic inflammatory diseases: toward new therapeutic targets?
2017
Introduction: Macrophage activation syndrome (MAS) is a severe, hyperinflammatory life-threatening syndrome, generally complicating different rheumatic diseases. Despite the severity of the disease, little is known about the pathogenic mechanisms and, thus, possible targeted therapies in the management of these patients. Areas covered: In this review, we aimed to update the current pathogenic knowledge of MAS, during rheumatic diseases, focusing mainly on immunologic abnormalities and on new possible therapeutic strategies. Expert commentary: The difficult pathogenic scenario of MAS, in which genetic defects, predisposing diseases, and triggers are mixed together with the high mortality rat…
Metabolic Profiling of Glucose-Fed Metabolically Active Resting Zymomonas mobilis Strains
2020
Zymomonas mobilis is the most efficient bacterial ethanol producer and its physiology is potentially applicable to industrial-scale bioethanol production. However, compared to other industrially important microorganisms, the Z. mobilis metabolome and adaptation to various nutritional and genetic perturbations have been poorly characterized. For rational metabolic engineering, it is essential to understand how central metabolism and intracellular redox balance are maintained in Z. mobilis under various conditions. In this study, we applied quantitative mass spectrometry-based metabolomics to explore how glucose-fed non-growing Z. mobilis Zm6 cells metabolically adapt to change of oxygen avai…
Opettajat aikuisten maahanmuuttajien perustaitoja kehittämässä
2021
Artikkelissa tarkastellaan, miten aikuisten maahanmuuttajaopiskelijoiden opettajat ymmärtävät perustaidot ja opiskelutaidot sekä miten he pedagogisoivat perustaitojen opetusta arvioinnin avulla. Perustaitoja ovat luku- ja kirjoitustaidot, numeeriset taidot ja ongelmanratkaisutaidot teknologisesti kehittyneissä ympäristöissä. Aineisto kerättiin opettajien täydennyskoulutuksessa ja se koostuu opettajien laatimista arviointi- ja oppimistehtävistä sekä reflektoinneista. Aineisto analysoitiin teoriaohjaavalla sisällönanalyysilla. Tulosten mukaan täydennyskoulutukseen osallistuneet opettajat näkivät perustaidot usein toisistaan erillisinä eivätkä välttämättä huomioineet aikuisten maahanmuuttajaop…
Oxidative Stress in COPD.
2019
Numerous studies over the years have shown that oxidative stress plays a major role in the development of the disease. Oxidative stress involvement in COPD opens up the possibility of using antioxidant therapies in the treatment of the disease. However, so far, these therapies have shown no clinical benefit indicating that more basic research efforts are needed to understand the underlying mechanisms by which oxidative stress leads to the development of COPD.
Sinemurian to lowermost Toarcian ammonites of the Brescian Prealps (Southern Alps, Italy): preliminary biostratigraphical framework and correlations.
2009
10 pages; International audience; A set of 28 ammonite biohorizons or faunal assemblages is proposed for the Sinemurian, the Pliensbachian and the lowermost Toarcian of the Brescian Prealps, in part based on the published data of the authors of this contribution and partly on new results, derived both from recent field investigations and from the study of the historical collection of Lower Jurassic ammonites preserved in the Museum of Natural Sciences of Brescia (Northern Italy). The biohorizons are present in the Liassic carbonate succession of the Brescian Prealps, cropping out between the eastern surroundings of Brescia (Botticino), to the east, and Lake Iseo, to the west. Since the Hett…
Complete Genome Sequence of a New Ruminococcaceae Bacterium Isolated from Anaerobic Biomass Hydrolysis
2018
ABSTRACT A new Ruminococcaceae bacterium, strain HV4-5-B5C, participating in the anaerobic digestion of grass, was isolated from a mesophilic two-stage laboratory-scale leach bed biogas system. The draft annotated genome sequence presented in this study and 16S rRNA gene sequence analysis indicated the affiliation of HV4-5-B5C with the family Ruminococcaceae outside recently described genera.
Elevage et consommation en territoire arverne. : De l'agglomération d'Aulnat aux oppida du bassin clermontois, changements ou continuité ?
2010
Textes en français et en allemand. - Actes du 34ème colloque de l'AFEAF organisé du 13 au 16 mai 2010 à Aschaffenburg Allemagne). - Textes et avant-propos en allemand et en français. Bibliogr. en fin de contributions; International audience
Distinct 5' SCL enhancers direct transcription to developing brain, spinal cord, and endothelium: neural expression is mediated by GATA factor bindin…
1999
The SCL gene encodes a basic helix-loop-helix transcription factor with a pivotal role in the development of endothelium and of all hematopoietic lineages. SCL is also expressed in the central nervous system, although its expression pattern has not been examined in detail and its function in neural development is unknown. In this article we present the first analysis of SCL transcriptional regulation in vivo. We have identified three spatially distinct regulatory modules, each of which was both necessary and sufficient to direct reporter gene expression in vivo to three different regions within the normal SCL expression domain, namely, developing endothelium, midbrain, and hindbrain/spinal …
Extensions of known geographic distribution of aphyllophoroid fungi (Basidiomycota) in Finland
2016
Article
Promoting Research and Landscape Experience in the Management of the Archaeological Networks. A Project-Valuation Experiment in Italy
2020
Archaeological sites are part of the history and identity of a community playing a strategic role on the different scales of the cultural and economic common life. Whereas on the one end the most famous archaeological sites attract huge flows of tourists and investment, on the other hand, many minor archaeological sites remain almost ignored and neglected. This study proposes a project-evaluation approach devoted to the &ldquo