Search results for "bat"

showing 10 items of 4075 documents

Rupture of supra-aortic neck arteries due to lesions caused by tracheal tubes

1984

Haemorrhages from the common carotid or innominate artery caused by tracheal tubes are rare but dramatic complications of head and neck surgery. Patients with metal tracheostomy cannulas or patients in the phase of wound healing after radical tumour resections of the pharynx and larynx run a greater risk. Following extensive tumour resections and radiation of the upper respiratory and digestive tracts in 680 patients, acute bleeding of the larger neck arteries occurred in 18 patients. In four of these cases, fistulae developed in the innominate or common carotid artery. These ruptures were caused by both plastic and metal tracheal tubes.

AdultMaleLarynxmedicine.medical_specialtyHemorrhagePostoperative Complicationsmedicine.arteryIntubation IntratrachealmedicineHumansCommon carotid arteryRespiratory systemLaryngeal NeoplasmsBrachiocephalic TrunkAgedRupturebusiness.industryPharynxGeneral MedicineMiddle AgedSurgerymedicine.anatomical_structureOtorhinolaryngologyHead and neck surgeryDigestive tractCarotid Artery InjuriesbusinessAortic neckArteryThe Journal of Laryngology & Otology
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In vivo ultrasound real-time motion of the cervical spine during intubation under manual in-line stabilization: a comparison of intubation methods

2007

Background and objectiveIn emergency trauma situations, manual in-line stabilization of the cervical spine is recommended to reduce cervical spine movement during intubation. The aim of this study was to compare the effect of manual in-line stabilization during different intubation techniques on three-dimensional cervical spine movements and times to intubation.MethodsForty-eight subjects without any history of trauma, inflammatory or degenerative disorder of the cervical spine were randomly grouped, regardless of gender or age. All underwent elective surgery under general anaesthesia. Under manual in-line stabilization, laryngeal intubation with Macintosh laryngoscope, intubating laryngeal…

AdultMaleLarynxmedicine.medical_specialtymedicine.medical_treatmentPostureAnesthesia GeneralLaryngoscopesMotor ActivityOnline SystemsBody Mass IndexmedicineFiber Optic TechnologyHumansIntubationGeneral anaesthesiaElective surgeryUltrasonographybusiness.industryUltrasoundMiddle AgedSurgeryLaryngeal MasksAnesthesiology and Pain Medicinemedicine.anatomical_structureElective Surgical ProceduresAnesthesiaCervical VertebraeFemaleAirway managementLarynxIntubationbusinessElective Surgical ProcedureEuropean Journal of Anaesthesiology
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Increased in vitro cvsteinvl leukotriene release from blood leukocytes in patients with asthma, nasal polyps, and aspirin intolerance

1996

In vitro cysteinyl leukotriene (cLT) release from blood leukocytes was measured in eight normal individuals (NI), nine patients with nasal polyps (NP) without aspirin intolerance, and eight patients with NP, asthma, and aspirin intolerance (AI). Blood leukocytes were prestimulated with interleukin-3 (IL-3) and incubated with acetylsalicylic acid (ASA) (10 and 100 micrograms/ml) together with C5a (10(-8) mol/l) for 18 h. cLT release (LTC4, LTD4 and LTE4) from blood leukocytes was measured with a competitive enzyme-linked immunoassay. Background cLT release was 259 +/- 66 pg/ml (mean +/- SEM) in the NI group, 185 +/- 33 pg/ml in the NP group, and 578 +/- 136 pg/ml in the AI group (P = 0.1). A…

AdultMaleLeukotrienesmedicine.medical_specialtyLeukotriene B4ImmunologyDrug Hypersensitivitychemistry.chemical_compoundNasal PolypsInternal medicineLeukocytesmedicineHumansImmunology and AllergyNasal polypsIncubationAsthmaLeukotriene E4AspirinLeukotriene C4business.industryMiddle Agedmedicine.diseaseAsthmaIn vitroEndocrinologychemistryToxicityImmunologyFemalebusinessAllergy
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Hepatitis A-like non-A, non-B hepatitis: light and electron microscopic observations of three cases.

1986

To date, three types of NANBH have been distinguished by epidemiological, clinical and experimental data. We examined the liver biopsies of three patients with an acute NANBH resembling hepatitis A from the infection route, incubation period and clinical course. The liver biopsies revealed lesions with a portal and periportal predominance, thus also exhibiting parallels with hepatitis A on the histopathological level.

AdultMalePathologymedicine.medical_specialtyHepatitis Viral HumanBiologyPathology and Forensic MedicineIncubation periodHLA AntigensPregnancymedicineHumansMolecular BiologyElectron microscopicClinical courseHistocompatibility Antigens Class IIHepatitis ACell BiologyGeneral MedicineHLA-DR AntigensHepatitis AMiddle Agedmedicine.diseaseMicroscopy ElectronImmunologic TechniquesNon b hepatitisFemaleViral diseaseVirchows Archiv. A, Pathological anatomy and histopathology
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Water hardness and eczema at 1 and 4 y of age in the INMA birth cohort.

2015

Abstract Background: Exposure to hard water has been suggested as a risk factor for eczema in childhood, based on limited evidence from two ecologic and two cross-sectional studies. Objectives: We evaluate this hypothesis for the first time in early infancy using prospective data from a mother–child cohort study. Methods: We used data from the INMA cohorts in Gipuzkoa, Sabadell and Valencia, Spain (N=1638). Current and ever eczema, bathing frequency and duration and covariables were collected by questionnaires at 14 months (14 m) and 4 years (4 y). Calcium carbonate (CaCO3) level in municipal water was assigned to home addresses at birth, 14 m and 4 y. We calculated Odds Ratio (OR) of eczem…

AdultMalePediatricsmedicine.medical_specialtyBathingEczemaBiochemistryCohort StudiesRisk FactorsMedicineHumansRisk factorGeneral Environmental ScienceExposure assessmentbusiness.industryHard waterInfantWaterOdds ratioEnvironmental exposureAtopic dermatitisEnvironmental Exposuremedicine.diseaseSpainChild PreschoolFemalebusinessCohort studyDemographyEnvironmental research
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Differences in cannabis-related experiences between patients with a first episode of psychosis and controls

2016

BackgroundMany studies have reported that cannabis use increases the risk of a first episode of psychosis (FEP). However, only a few studies have investigated the nature of cannabis-related experiences in FEP patients, and none has examined whether these experiences are similar in FEP and general populations. The aim of this study was to explore differences in self-reported cannabis experiences between FEP and non-psychotic populations.MethodA total of 252 subjects, who met International Classification of Diseases (ICD)-10 criteria for FEP, and 217 controls who reported cannabis use were selected from the Genetics and Psychosis (GAP) study. The Medical Research Council Social Schedule and t…

AdultMalePsychosismedicine.medical_specialtyExacerbationPopulationMarijuana SmokingSociodemographic datapsychosiPsychotic Disorder03 medical and health sciencesYoung Adult0302 clinical medicineexperienceSurveys and QuestionnairesmedicineSettore MED/48 -Scienze Infermierist. e Tecn. Neuro-Psichiatriche e Riabilitat.HumansSurveys and QuestionnaireCannabiYoung adulteducationPsychiatrySettore MED/25 - PsichiatriaApplied PsychologyCannabisCannabis; Cannabis Experience Questionnaire; experiences; first episode of psychosis; psychosis; Adult; Cannabis; Female; Humans; Linear Models; Male; Marijuana Smoking; Psychiatric Status Rating Scales; Psychotic Disorders; Surveys and Questionnaires; Young Adult; Applied Psychology; Psychiatry and Mental Healthfirst episode of psychosiFirst episodePsychiatric Status Rating Scaleseducation.field_of_studybiologyCannabis usePsychiatric Status Rating Scalemedicine.diseasebiology.organism_classification030227 psychiatryPsychotic DisordersPsychiatry and Mental HealthCannabis Experience QuestionnaireLinear ModelsLinear ModelFemaleCannabisPsychology030217 neurology & neurosurgeryClinical psychologyHuman
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Comparing asthma treatment in elderly versus younger patients

2011

SummaryA randomised 6-month study compared two maintenance doses of budesonide/formoterol (Symbicort® Turbuhaler®)hhNeither the Symbicort SMART posology nor the dry powder formulation, Turbuhaler, is currently approved in the US. maintenance and reliever therapy (Symbicort SMART®), 160/4.5 μg 1 × 2 and 2 × 2, in 8053 asthmatics with symptoms despite treatment with inhaled corticosteroids ± inhaled long-acting β2-agonists. This analysis compared response to the two treatments in elderly patients, ≥65 years, with that in younger patients. Elderly patients with early- or late-onset asthma were also compared.Elderly patients had lower post-bronchodilator FEV1 percentage predicted normal at base…

AdultMalePulmonary and Respiratory MedicineBudesonideSymbicort SMARTmedicine.medical_specialtylaw.inventionExacerbationsElderlyRandomized controlled triallawFormoterol FumarateSurveys and QuestionnairesInternal medicineAdministration InhalationmedicineHumansBudesonideBudesonide/formoterolAgedAsthmaACQDose-Response Relationship Drugbusiness.industryHazard ratiomedicine.diseaseConfidence intervalAsthmaBronchodilator AgentsSurgeryTreatment OutcomeBudesonide/formoterolEthanolaminesAsthma Control QuestionnaireDisease ProgressionQuality of LifeDrug Therapy CombinationFemaleFormoterolbusinessmedicine.drugRespiratory Medicine
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Asthma control in severe asthmatics under treatment with omalizumab: A cross-sectional observational study in Italy

2015

Few data are available on the proportion of asthmatics achieving a good asthma control (according GINA guidelines) and on the level of airway inflammation during omalizumab treatment. The aim of this cross-sectional national observational study was to assess the level of control (according to GINA guidelines) achieved in a group of asthmatics on omalizumab treatment, and to characterize the factors that influence the lack of control. We studied 306 asthmatics under omalizumab treatment for a median of 32 months (range 4-120). The level of control according to GINA was good in 25.2%, partial in 47.1% and poor in 24.5% of patients (data were missing for the remaining 3.2%). Comparison between…

AdultMalePulmonary and Respiratory Medicinemedicine.medical_specialtyExacerbationCross-sectional studyOmalizumabOmalizumabComorbiditySettore MED/10 - Malattie Dell'Apparato RespiratorioExhaled nitric oxide; Exacerbations; Comorbidities; Asthma; Omalizumab; ControlSeverity of Illness IndexComorbiditiesExacerbationsExhaled nitric oxideInternal medicineSeverity of illnessControlMedicineAnti-Asthmatic AgentHumansPharmacology (medical)Anti-Asthmatic AgentsInflammation MediatorAsthmaRespiratory Function TestAgedCross-Sectional Studiebusiness.industryBiochemistry (medical)ExacerbationMiddle Agedmedicine.diseaseComorbidityAsthmaRespiratory Function TestsCross-Sectional StudiesItalyExhaled nitric oxidePhysical therapyObservational studyAsthma; Comorbidities; Control; Exacerbations; Exhaled nitric oxide; Omalizumab; Adult; Aged; Anti-Asthmatic Agents; Asthma; Comorbidity; Cross-Sectional Studies; Female; Humans; Inflammation Mediators; Italy; Male; Middle Aged; Omalizumab; Respiratory Function Tests; Severity of Illness Index; Pulmonary and Respiratory Medicine; Biochemistry (medical); Pharmacology (medical)FemaleComorbiditieInflammation Mediatorsbusinessmedicine.drugHuman
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Detection of gamma-hydroxybutyrate in hair: Validation of GC–MS and LC–MS/MS methods and application to a real case

2012

A gas chromatography-mass spectrometry (GC-MS) and a liquid chromatography tandem mass spectrometry (LC-MS/MS) method were validated for quantifying endogenous and exogenous hair concentrations of gamma-hydroxybutyrate (GHB). The GC-MS method is based on overnight extraction of 25 mg hair in NaOH at 56 °C, liquid/liquid extraction in ethylacetate and trimethylsylil derivatization; analysis is by electron ionization and single ion monitoring of three ions. The LC-MS/MS method entails a rapid digestion of 25 mg hair with NaOH at 75 °C for 40 min, liquid/liquid extraction in ethylacetate and reconstitution of the extract in the LC mobile phase; negative ion electrospray ionization and multiple…

AdultMaleQuality ControlSpectrometry Mass Electrospray IonizationSubstance-Related DisordersElectrospray ionizationClinical BiochemistryLiquid-Liquid ExtractionPharmaceutical ScienceAcetatesTandem mass spectrometryMass spectrometryGas Chromatography-Mass SpectrometryAnalytical ChemistryForensic ToxicologySettore MED/43 - Medicina LegaleLiquid chromatography–mass spectrometryLimit of DetectionTandem Mass SpectrometryDrug DiscoveryHumansSodium HydroxideSpectroscopyDetection limitChromatographyChemistryIllicit DrugsSelected reaction monitoringHair Segmental analysis GC–MS LC–MS/MSTemperatureReproducibility of ResultsGamma hydroxybutyrateReference StandardsSubstance Abuse DetectionGamma-hydroxybutyrate GHBCalibrationLinear ModelsCrimeGas chromatography–mass spectrometrySodium OxybateChromatography LiquidHair
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Construction of quality of life change patterns: example in oncology in a phase III therapeutic trial (FFCD 0307)

2015

Objective Quality of life data in cancerology are often difficult to summarize due to missing data and difficulty to analyze the pattern of evolution in different groups of patients. The aim of this work was to apply a new methodology to construct Quality of Life (QoL) change patterns within patients included in a clinical trial comparing to regimen of treatment in locally advanced eosogastric cancer. Materials and methods In this trial, QoL was assessed every 2 months by self-reported EORTC QLQ-C30 questionnaire. Physical dimension scores were analyzed. After multiple imputation of missing data, 27 statistical measures aiming to describe the variation of QoL measures among follow-up were c…

AdultMaleQuality of lifemedicine.medical_specialtyEsophageal NeoplasmsPsychometricsPsychometricsMEDLINEChange patternsPhase (combat)ClusteringQuality of lifeSickness Impact ProfileSurveys and QuestionnairesAdaptation PsychologicalHealth Status IndicatorsHumansMedicineMedical physicsAgedbusiness.industryManagement scienceResearchPublic Health Environmental and Occupational HealthGeneral MedicineMiddle AgedMissing datahumanitiesClinical trialRegimenClinical Trials Phase III as TopicMultiple imputationFemaleConstruct (philosophy)businessHealth and Quality of Life Outcomes
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