Search results for "bee"
showing 10 items of 628 documents
Identification of calcium sensing receptor (CaSR) mRNA-expressing cells in normal and injured rat brain
2009
Calcium sensing receptor (CaSR), isolated for the first time from bovine and human parathyroid, is a G-protein-coupled receptors that has been involved in diverse physiological functions. At present a complete in vivo work on the identification of CaSR mRNA-expressing cells in the adult brain lacks and this investigation was undertaken in order to acquire more information on cell type expressing CaSR mRNA in the rat brain and to analyse for the first time its expression in different experimental models of brain injury. The expression of CaSR mRNAs was found mainly in scattered cells throughout almost all the brain regions. A double labeling analysis showed a colocalization of CaSR mRNA expr…
Thermal and dynamic mechanical properties of beeswax-halloysite nanocomposites for consolidating waterlogged archaeological woods
2015
Abstract Thermal and mechanical properties were determined for the halloysite nanotubes (HNT)/beeswax composites at various compositions. The beeswax degradation temperatures and time course, provided by thermogravimetry (TG), evidenced the improvement of the thermal properties operated by HNT. Differential scanning calorimetry (DSC) allowed us to determine the enthalpy of melting as well as the time course of the melting process for beeswax. A slight loss of beeswax crystallinity was observed upon HNT addition. The dynamical mechanical analysis (DMA) provided the loss and the storage modulus for the nanocomposites upon heating and it was shown that the nanoclays create an inorganic framewo…
A hybrid metaheuristic for the cyclic antibandwidth problem
2013
We propose a hybrid artificial bee colony algorithm for the cyclic antibandwidth problem.We present a computational comparison of different parameter settings.We derive a fine-tuning hybrid artificial bee colony algorithm.The proposal is very competitive with the state-of-the-art algorithm for the cyclic antibandwidth problem. In this paper, we propose a hybrid metaheuristic algorithm to solve the cyclic antibandwidth problem. This hard optimization problem consists of embedding an n-vertex graph into the cycle Cn, such that the minimum distance (measured in the cycle) of adjacent vertices is maximized. It constitutes a natural extension of the well-known antibandwidth problem, and can be v…
New insights into Early Celtic consumption practices: Organic residue analyses of local and imported pottery from Vix-Mont Lassois
2019
The rich Mediterranean imports found in Early Celtic princely sites (7th-5th cent. BC) in Southwestern Germany, Switzerland and Eastern France have long been the focus of archaeological and public interest. Consumption practices, particularly in the context of feasting, played a major role in Early Celtic life and imported ceramic vessels have consequently been interpreted as an attempt by the elite to imitate Mediterranean wine feasting. Here we present the first scientific study carried out to elucidate the use of Mediterranean imports in Early Celtic Central Europe and their local ceramic counterparts through organic residue analyses of 99 vessels from Vix-Mont Lassois, a key Early Celti…
Production and turnover of organic matter in three southern European Fagus sylvatica L
1999
Above-ground biomass, litterfall and litter accumulation and decomposition at the soil surface were studied within three Mediterranean beech forests from Italy, France and Spain in order to better understand the recycling of elements associated with the turnover organic matter Above-ground tree biomass amounted to 131.9 Mg ha-1 at Etna (Italy), 134.2 Mg ha-1 at Sierra de la Demanda (Spain) and 223.9 Mg ha-1 at Mont Lozère (France). The highest amount of total litterfall was observed at Sierra de la Demanda (4.7 Mg ha-1 year-1), followed by the Mont Lozère (4.4 Mg ha-1 year-1) and Etna (3.9 Mg ha-1 year-1). Total organic matter accumulated on the soil surface in the three beech forests amoun…
Using On-Demand File Systems in HPC Environments
2019
In modern HPC systems, parallel (distributed) file systems are used to allow fast access from and to the storage infrastructure. However, I/O performance in large-scale HPC systems has failed to keep up with the increase in computational power. As a result, the I/O subsystem which also has to cope with a large number of demanding metadata operations is often the bottleneck of the entire HPC system. In some cases, even a single bad behaving application can be held responsible for slowing down the entire HPC system, disrupting other applications that use the same I/O subsystem. These kinds of situations are likely to become more frequent in the future with larger and more powerful HPC systems…
Honey Bee Suppresses the Parasitic Mite Vitellogenin by Antimicrobial Peptide
2020
AbstractThe negative effects of honey bee parasitic mites and deformed wing virus (DWV) on honey bee and colony health have been well characterized. However, the relationship between DWV and mites, particularly viral replication inside the mites, remains unclear. Furthermore, the physiological outcomes of honey bee immune responses stimulated by DWV and the mite to the host (honey bee) and perhaps the pathogen/parasite (DWV/mite) are not yet understood. To answer these questions, we studied the tripartite interactions between the honey bee,Tropilaelaps mercedesae, and DWV as the model.T. mercedesaefunctioned as a vector for DWV without supporting active viral replication. Thus, DWV negligib…
The Role of Yeasts in Fermentation Processes
2020
In recent years, vessels have been discovered that contain the remains of wine with an age close to 7000 years. It is unclear whether, in ancient times, humans accidentally stumbled across fermented beverages like wine or beer, or was it a product intended as such. What is a fact is that since then, alcoholic beverages have been part of the diet and culture of many of the civilizations that have preceded us. The typical examples of beer and wine are an example of many other drinks resulting from the action of yeasts. In addition to these two beverages, various companies have developed other types of fermented foods and non-alcoholic beverages prepared in a traditional or commercial manner. …
Pharmacogenomics of cantharidin in tumor cells.
2014
Cantharis vesicatoria (blister beetle) is used in Chinese medicine and has been categorized as highly toxic in the Chinese pharmacopeia. In Europe, Cantharis patches have been used since ages to treat various skin-related diseases. We investigated the cytotoxicity of the Cantharis ingredient, cantharidin, in 41 tumor cell lines (Oncotest panel) and compared the results with those of 60 cell lines of the National Cancer Institute, USA. We found profound activity at low micromolar concentrations (log ₁₀IC₅₀ values between -6.980 and 5.009 M). Cantharidin bound to protein phosphatase 2A (PP2A) with higher affinity (-8.12 kcal/mol) than to PP1 (-6.25 kcal/mol) in molecular docking analyses. Usi…
A molecular assembly system that renders antigens of choice highly repetitive for induction of protective B cell responses.
2002
Virus like particles (VLPs) are known to induce potent B cell responses in the absence of adjuvants. Moreover, epitope-specific antibody responses may be induced by VLPs that contain peptides inserted in their immunodominant regions. However, due to steric problems, the size of the peptides capable of being incorporated into VLPs while still permitting capsid assembly, is rather limited. While peptides genetically fused to either the N- or C-terminus of VLPs present fewer assembly problems, the immune responses obtained against such epitopes are often limited, most likely because the epitopes are not optimally exposed. In addition, such particles may be less stable in vivo. Here, we show th…