Search results for "behavior"
showing 10 items of 13975 documents
2021
Abstract Reliable paradigms and imaging measures of individual-level brain activity are paramount when reaching from group-level research studies to clinical assessment of individual patients. Magnetoencephalography (MEG) provides a direct, non-invasive measure of cortical processing with high spatiotemporal accuracy, and is thus well suited for assessment of functional brain damage in patients with language difficulties. This MEG study aimed to identify, in a delayed picture naming paradigm, source-localized evoked activity and modulations of cortical oscillations that show high test–retest reliability across measurement days in healthy individuals, demonstrating their applicability in cli…
Picture naming yields highly consistent cortical activation patterns: test-retest reliability of magnetoencephalography recordings
2020
AbstractReliable paradigms and imaging measures of individual-level brain activity are paramount when reaching from group-level research studies to clinical assessment of individual patients. Magnetoencephalography (MEG) provides a direct, non-invasive measure of cortical processing with high spatiotemporal accuracy, and is thus well suited for assessment of functional brain damage in patients with language difficulties. This MEG study aimed to identify, in a picture naming paradigm, source-localized evoked activity and modulations of cortical oscillations that show high test-retest reliability across measurement days in healthy individuals, demonstrating their applicability in clinical set…
2020
Interruptions (interfering stimuli to respond to) and distractions (interfering stimuli to be ignored) have been shown to negatively impact performance, particularly in tasks requiring working memory (WM). This study investigated how these two types of external interference affect task performance and attentional and WM processes as indexed by specific event-related potentials (ERPs) of the EEG. A Continuous Number Task (CNT) was applied, in which participants had to either decide whether the current number (condition without WM load) or the sum of the current and the preceding number (condition with WM load) was odd or even while responding to interlaced single letters (interruptions) or i…
Sleep restriction for the duration of a work week impairs multitasking performance
2010
It is important to develop shift schedules that minimise the chance for sleep-related human error in safety-critical domains. Experimental data on the effects of sleep restriction (SR) play a key role in this development work. In order to provide such data, we conducted an experiment in which cognitively demanding and long-duration task performance, simulating task performance at work, was measured under SR and following recovery. Twenty healthy male volunteers, aged 19-29 years, participated in the study. Thirteen of them had first two baseline days (8-h sleep opportunity per day), then five SR days (4-h sleep) and finally two recovery days (8-h sleep). Seven controls were allowed to sleep…
Functional MRI and motor behavioral changes obtained with constraint-induced movement therapy in chronic stroke
2011
Background: The clinical benefits of intensive stroke rehabilitation vary individually. We used multimodal functional imaging to assess the relationship of clinical gain and imaging changes in patients with chronic stroke whose voluntary motor control improved after constraint-induced movement therapy (CIMT). Methods: Eleven patients (37.6 ± 36.8 months from stroke) were studied by functional MRI (fMRI), transcranial magnetic stimulation (TMS), and behavioral assessment of hand motor control (Wolf Motor Function Test) before and after 2 weeks of CIMT. Individual and group-level changes in imaging and behavioral parameters were investigated. Results: Increase in fMRI activation in the sen…
Title effect of multicomponent cognitive behavioral therapy in a sample of chronic insomniacs in hypnotic treatment
2013
Introduction The objective of this study is to analyze the improvements in sleep and quality of life, as well as to evaluate the decrease or cessation of drug treatment in a sample of insomniacs in hypnotic drug treatment after CBT-I application. Materials and methods This is a pre-post quasi-experimental design, with a monitoring performed 6 months later in which information of an Experimental Group (EG = 17) is given and evaluated during three times, and also a Control Group (CG = 44), with measures only at the pre- post. According to Perlis Protocol and after an Insomnia Interview by Morin, all patients qualified as candidates for CBTI. Patients were given a daily sleep log and the Spa…
Mania associated with antidepressant treatment: comprehensive meta-analytic review
2009
Tondo L, Vazquez G, Baldessarini RJ. Mania associated with antidepressant treatment: comprehensive meta-analytic review. Objective: To review available data pertaining to risk of mania–hypomania among bipolar (BPD) and major depressive disorder (MDD) patients with vs. without exposure to antidepressant drugs (ADs) and consider effects of mood stabilizers. Method: Computerized searching yielded 73 reports (109 trials, 114 521 adult patients); 35 were suitable for random effects meta-analysis, and multivariate-regression modeling included all available trials to test for effects of trial design, AD type, and mood-stabilizer use. Results: The overall risk of mania with/without ADs averaged …
Psycho-Social Factors in Patients with Cardiovascular Disease Attending a Family-Centred Prevention and Rehabilitation Programme: EUROACTION Model in…
2021
Background: Coronary heart disease (CHD) persists as the leading cause of death worldwide. Cardiovascular prevention and rehabilitation (CVPR) has an interdisciplinary focus, and includes not only in physiological components, but it also addresses psycho-social factors. Methods: The study analysed the Spanish psycho-social data collected during the EUROACTION study. In Spain, two hospitals were randomised in the Valencia community. Coronary patients were prospectively and consecutively identified in both hospitals. The intervention hospital carried out a 16-week CVPR programme, which aimed to assess illness perceptions and establish healthy behaviours in patients and their partners. Results…
Attention-deficit/hyperactivity disorder in adults: update on clinical presentation and care
2014
Attention-deficit/hyperactivity disorder (ADHD) is characterized by traitlike symptoms, with stable features frequently emerging in early childhood and persisting throughout adolescence and adulthood. The hallmarks are pervasive, developmentally inappropriate levels of inattention, hyperactivity and impulsivity leading to impairments in family life, social life, academic performance, and occupational functioning. Emotional lability is a commonly associated feature that is a further source of impairment. Diagnosis rests on a comprehensive assessment of developmental psychiatric history and current status, following DSM-5 guidelines on ADHD classification and diagnostic thresholds for adults.…
The diagnosis of and treatment recommendations for anxiety disorders.
2014
Anxiety disorders (panic disorder/agoraphobia, generalized anxiety disorder, social phobia, and specific phobias) are the most common mental illnesses. For example, the 12-month prevalence of panic disorder/agoraphobia is 6%.This guideline is based on controlled trials of psychotherapy and pharmacotherapy, retrieved by a systematic search for original articles that were published up to 1 July 2013. Experts from 20 specialty societies and other organizations evaluated the evidence for each treatment option from all available randomized clinical trials and from a synthesis of the recommendations of already existing international and German guidelines.403 randomized controlled trials were eval…