Search results for "being"

showing 10 items of 1477 documents

Trends in multiple recurrent health complaints in 15-year-olds in 35 countries in Europe, North America and Israel from 1994 to 2010

2015

Background: Health complaints are a good indicator of an individual’s psychosocial health and well-being. Studies have shown that children and adolescents report health complaints which can cause significant individual burden. Methods: Using data from the international Health Behaviour in School-aged Children study, this article describes trends in multiple recurrent health complaints (MHC) in 35 countries among N = 237 136 fifteen-year-olds from 1994 to 2010. MHC was defined as the presence of two or more health complaints at least once a week. Logistic regression analysis was performed to evaluate trends across the five survey cycles for each country. Results: Lowest prevalence thro…

MalePediatricsmedicine.medical_specialtyAdolescentHealth StatusAdolescent HealthLogistic regressionPrevalenceHumansMedicineIsraelhealth and well-beingSchool age childbusiness.industryEnvironmental and Occupational HealthPublic Health Environmental and Occupational HealthInternational healthta3141ta3142BenchmarkingHealth SurveysQuadratic trendEuropeNorth AmericaFemalePublic Healthtrend analysisHealth behaviorbusinessPsychosocialDemographyThe European Journal of Public Health
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Comparing Long-Acting Antipsychotic Discontinuation Rates Under Ordinary Clinical Circumstances: A Survival Analysis from an Observational, Pragmatic…

2021

Background Recent guidelines suggested a wider use of long-acting injectable antipsychotics (LAI) than previously, but naturalistic data on the consequences of LAI use in terms of discontinuation rates and associated factors are still sparse, making it hard for clinicians to be informed on plausible treatment courses. Objective Our objective was to assess, under real-world clinical circumstances, LAI discontinuation rates over a period of 12 months after a first prescription, reasons for discontinuation, and associated factors. Methods The STAR Network ‘Depot Study’ was a naturalistic, multicentre, observational prospective study that enrolled subjects initiating a LAI without restrictions …

MalePediatricsrespectively)0302 clinical medicineDelayed-Action PreparationBrief Psychiatric Rating ScalePharmacology (medical)he STAR Network ‘Depot Study’ prospectively followed 394 subjects initiating treatment with long-acting injections (LAIs) of antipsychotics under naturalistic conditions for 12 months. LAI discontinuation was frequent in everyday clinical practice in ItalyOriginal Research ArticleProspective StudiesProspective cohort studytreatmentMental DisordersHazard ratiowhereas more than half of participants initiating risperidone LAI and olanzapine LAI discontinued during the 12 months of follow-up (51.4 and 62.5%Psychiatric Status Rating ScaleMiddle Agedside efectsPsychiatry and Mental healthItalyMental DisorderFemalehe STAR Network ‘Depot Study’ prospectively followed 394 subjects initiating treatment with long-acting injections (LAIs) of antipsychotics under naturalistic conditions for 12 months. LAI discontinuation was frequent in everyday clinical practice in Italy occurring in almost 40% of the entire sample; side efects participant refusal to continue LAIs and LAIs no longer being required were the most frequently reported reasons for discontinuation. Paliperidone LAI and aripiprazole LAI were the least discontinued medications (33.9 and 35.4% respectively) whereas more than half of participants initiating risperidone LAI and olanzapine LAI discontinued during the 12 months of follow-up (51.4 and 62.5% respectively). In multivariate analysis being prescribed olanzapine LAI and poor medication adherence at baseline were signifcantly associated with higher discontinuation risk.HumanAntipsychotic Agentsmedicine.drugPsychopathologyAdultmedicine.medical_specialtyDiscontinuationFollow-Up StudieMedication Adherence03 medical and health sciencesmedicineHumansPaliperidoneAdverse effectSettore MED/25 - Psichiatriadiscontinuation ratesPsychiatric Status Rating Scalesrespectively). In multivariate analysisbusiness.industryLong-Acting Antipsychoticlong-acting injectable antipsychoticsSurvival AnalysisConfidence intervalparticipant refusal to continue LAIs and LAIs no longer being required were the most frequently reported reasons for discontinuation. Paliperidone LAI and aripiprazole LAI were the least discontinued medications (33.9 and 35.4%030227 psychiatryDiscontinuationProspective StudieAntipsychotic Agentoccurring in almost 40% of the entire sampleDelayed-Action PreparationsNeurology (clinical)business030217 neurology & neurosurgerybeing prescribed olanzapine LAI and poor medication adherence at baseline were signifcantly associated with higher discontinuation riskFollow-Up Studies
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Global, regional, and national progress towards Sustainable Development Goal 3.2 for neonatal and child health: all-cause and cause-specific mortalit…

2021

Background: Sustainable Development Goal 3.2 has targeted elimination of preventable child mortality, reduction of neonatal death to less than 12 per 1000 livebirths, and reduction of death of children younger than 5 years to less than 25 per 1000 livebirths, for each country by 2030. To understand current rates, recent trends, and potential trajectories of child mortality for the next decade, we present the Global Burden of Diseases, Injuries, and Risk Factors Study (GBD) 2019 findings for all-cause mortality and cause-specific mortality in children younger than 5 years of age, with multiple scenarios for child mortality in 2030 that include the consideration of potential effects of COVID-…

MalePerinatal careNewborn careSTILLBIRTHSRJ101UNDER-5 MORTALITYPsychological intervention010501 environmental sciencesInfant mortalityGlobal Health01 natural sciences0302 clinical medicineRA0421Cause of DeathInfant MortalityGlobal healthLife TablesHealthcare improvements030212 general & internal medicine610 Medicine & healthChildCause of Death; Child; COVID-19; Global Health; Humans; Infant; Life Tables; SARS-CoV-2; Sustainable Development11 Medical and Health SciencesCause of deathLife TableMortality rate1. No povertyPublic Health Global Health Social Medicine and EpidemiologyGeneral MedicineArticlesHälsovetenskaperSustainable DevelopmentMortality analyses3. Good healthPeer reviewChild PreschoolSDG 1 - No PovertyChild MortalityFemaleLife Sciences & BiomedicineHumanChild mortalityCOUNTRIESDEATHSInfants -- MortalitatGBD610 Medicine & health03 medical and health sciencesMedicine General & InternalSDG 3 - Good Health and Well-beingLife tablesunder-5 mortality rateGeneral & Internal MedicineHealth SciencesNeonatal deathsmedicineSYSTEMATIC ANALYSISHumans:Medicine [Science]Infants -- SalutPreschool0105 earth and related environmental sciencesScience & TechnologyInfants nadons -- Salutbusiness.industrySARS-CoV-2Infants nadons -- MortalitatINFORMInfant NewbornCOVID-19InfantNeonatal and child health ; Sustainable Development Goal 3.2 ; Global healthGBD 2019 Under-5 Mortality Collaboratorsmedicine.diseaseNewbornTRENDSInfant mortalitySustainable Development GoalChild mortalityFolkhälsovetenskap global hälsa socialmedicin och epidemiologiDeaths3121 General medicine internal medicine and other clinical medicineRGbusinessSystematic AnalysisMalariaDemography
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Being moved by listening to unfamiliar sad music induces reward‐related hormonal changes in empathic listeners

2021

Many people enjoy sad music, and the appeal for tragedy is widespread among the consumers of film and literature. The underlying mechanisms of such aesthetic experiences are not well understood. We tested whether pleasure induced by sad, unfamiliar instrumental music is explained with a homeostatic or a reward theory, each of which is associated with opposite patterns of changes in the key hormones. Sixty-two women listened to sad music (or nothing) while serum was collected for subsequent measurement of prolactin (PRL) and oxytocin (OT) and stress marker (cortisol and adrenocorticotropic hormone) concentrations. Two groups of participants were recruited on the basis of low and high trait e…

MalePleasuremelankoliaSALIVARY CORTISOLSTRESSEmotionsKey (music)Developmental psychologyDOPAMINE0302 clinical medicinehydrokortisoniSocial rejectionmedia_commonGeneral Neurosciencemieliala05 social sciencessurubeing movedhumanitiesSadnessRECEPTOR GENERELAXING MUSICoksitosiiniFemalePsychologysadnesspsychological phenomena and processesprolactinOXYTOCIN RELEASE515 Psychologymedia_common.quotation_subjectmusiikkiEmpathycortisolbehavioral disciplines and activities050105 experimental psychologyGeneral Biochemistry Genetics and Molecular BiologykuunteleminenPleasure03 medical and health sciencesSOCIAL REJECTIONRewardHistory and Philosophy of SciencetunteetLow arousal theorySadnessoxytocinHumans0501 psychology and cognitive sciencesActive listeningmusicHormoneshormonit6131 Theatre dance music other performing artsMood3111 BiomedicineEmpathyBiomarkersMusic030217 neurology & neurosurgeryRESPONSES
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Selection analysis on the rapid evolution of a secondary sexual trait

2015

Evolutionary analyses of population translocations (experimental or accidental) have been important in demonstrating speed of evolution because they subject organisms to abrupt environmental changes that create an episode of selection. However, the strength of selection in such studies is rarely measured, limiting our understanding of the evolutionary process. This contrasts with long-term, mark–recapture studies of unmanipulated populations that measure selection directly, yet rarely reveal evolutionary change. Here, we present a study of experimental evolution of male colour in Trinidadian guppies where we tracked both evolutionary change and individual-based measures of selection. Guppie…

MalePopulationLongevityGenetic FitnessColorBiologyMating PreferenceMedical and Health SciencesGeneral Biochemistry Genetics and Molecular BiologyMark and recaptureGeneticGeneticssexual selectionAnimalsSelection GeneticeducationSelectionrapid evolutionResearch ArticlesGeneral Environmental ScienceExperimental evolutioneducation.field_of_studyPoeciliaGeneral Immunology and MicrobiologyReproductive successAgricultural and Veterinary SciencesAnimalHuman GenomeGeneral MedicineBiological SciencesMating Preference AnimalBiological EvolutionfitnessGenetic divergenceGood Health and Well BeingPhenotypeEvolutionary biologySexual selectioncommon garden experimentsTraitta1181mark–recaptureGenetic FitnessGeneral Agricultural and Biological Sciencesmark-recapture
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Incidence and types of complications after ablative oral cancer surgery with primary microvascular free flap reconstruction.

2015

Background: The aims of the study were 1) to evaluate the incidence and types of postoperative complications after ablative oral cancer surgery with primary free flap reconstruction and 2) identify prognostic variables for postoperative complications. Material and Methods: Desired data was retrieved from a computer database at the department of Oral and Maxillofacial Department, Queen Elisabeth hospital Birmingham, United Kingdom, between June 2007 and October 2012. Logistic regression was used to study relationships between preoperative variables and postoperative outcomes. Results: The study population consisted 184 patients, comprising 189 composite resections with reconstruction. Compli…

MalePrognostic variablemedicine.medical_specialtyOdontologíaFree flapLogistic regressionFree Tissue FlapsPostoperative ComplicationsSDG 3 - Good Health and Well-beingAblative caseMedicineHumansGeneral DentistryRetrospective StudiesMouth neoplasmbusiness.industryIncidence (epidemiology)IncidenceResearchRetrospective cohort studyLength of StayMiddle Aged:CIENCIAS MÉDICAS [UNESCO]PrognosisCiencias de la saludSurgeryOtorhinolaryngologyUNESCO::CIENCIAS MÉDICASMicrovessels/dk/atira/pure/sustainabledevelopmentgoals/good_health_and_well_beingPopulation studySurgeryFemaleMouth NeoplasmsOral SurgerybusinessMedicina oral, patologia oral y cirugia bucal
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Healthy Learning Mind - a school-based mindfulness and relaxation program: a study protocol for a cluster randomized controlled trial

2016

Abstract Background Mindfulness has shown positive effects on mental health, mental capacity and well-being among adult population. Among children and adolescents, previous research on the effectiveness of mindfulness interventions on health and well-being has shown promising results, but studies with methodologically sound designs have been called for. Few intervention studies in this population have compared the effectiveness of mindfulness programs to alternative intervention programs with adequate sample sizes. Methods/design Our primary aim is to explore the effectiveness of a school-based mindfulness intervention program compared to a standard relaxation program among a non-clinical c…

MaleProgram evaluation050103 clinical psychologyChildren and adolescentsMindfulnessAdolescent515 PsychologyWell-beingPopulationPsychological interventionContext (language use)Relaxation Therapylaw.inventionStudy ProtocolRandomized controlled triallawSurveys and QuestionnairesIntervention (counseling)Humans0501 psychology and cognitive sciencesChildStudentseducationFinlandGeneral PsychologySchool Health Serviceseducation.field_of_studySchool-based intervention4. EducationPsykologia - Psychology05 social sciencesGeneral MedicineMental health3142 Public health care science environmental and occupational health3. Good healthMental Health5144 Social psychologyHealth promotionFemale516 Educational sciencesPsychologyMindfulnessKasvatustieteet - Educational sciencesProgram Evaluation050104 developmental & child psychologyClinical psychologyBMC Psychology
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KRAS and BRAF mutations in circulating tumour DNA from locally advanced rectal cancer.

2018

Abstract There are limited data on circulating, cell-free, tumour (ct)DNA analysis in locally advanced rectal cancer (LARC). Digital droplet (dd)PCR was used to investigate KRAS/BRAF mutations in ctDNA from baseline blood samples of 97 LARC patients who were treated with CAPOX followed by chemoradiotherapy, surgery and adjuvant CAPOX ± cetuximab in a randomised phase II trial. KRAS mutation in G12D, G12V or G13D was detected in the ctDNA of 43% and 35% of patients with tumours that were mutant and wild-type for these hotspot mutations, respectively, according to standard PCR-based analyses on tissue. The detection rate in the ctDNA of 10 patients with less common mutations was 50%. In 26 ca…

MaleProto-Oncogene Proteins B-rafOrganoplatinum CompoundsScienceCetuximabArticleCirculating Tumor DNAProto-Oncogene Proteins p21(ras)SDG 3 - Good Health and Well-beingAntineoplastic Combined Chemotherapy ProtocolsJournal ArticleHumansneoplasmsCapecitabineDigestive System Surgical ProceduresAgedRectal NeoplasmsQRChemoradiotherapy AdjuvantMiddle AgedPrognosisdigestive system diseasesOxaliplatinTreatment OutcomeMutation/dk/atira/pure/sustainabledevelopmentgoals/good_health_and_well_beingMedicineFemaleScientific reports
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Emotional intelligence in older adults: psychometric properties of the TMMS-24 and relationship with psychological well-being and life satisfaction.

2017

ABSTRACTBackground:Aging is a process during which important changes occur in different areas of development and emotional intelligence plays an essential role. The objective of this study was twofold: first, to validate the TMMS-24 in an older population; and second, to examine the mediating role of life satisfaction in the relationship between emotional intelligence and psychological well-being.Methods:The sample consisted of 215 older adults (60.15% women) with a mean age of 69.56 (SD = 6.42), without cognitive impairment. Data on emotional intelligence, satisfaction with life, and psychological well-being were obtained through the TMMS-24, the SWLS, and Ryff's psychological well-being s…

MalePsychometrics050109 social psychologyPersonal SatisfactionStructural equation modelingOlder population03 medical and health sciences0302 clinical medicineSurveys and QuestionnairesHumans0501 psychology and cognitive sciences030212 general & internal medicineCognitive impairmentAgedEmotional IntelligenceIntelligence TestsEmotional intelligence05 social sciencesLife satisfactionCognitionMiddle AgedPsychiatry and Mental healthClinical PsychologySpainPsychological well-beingWell-beingFemaleGeriatrics and GerontologyPsychologyFactor Analysis StatisticalGerontologySocial psychologyClinical psychologyInternational psychogeriatrics
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Therapy the Natural Way: A Realist Exploration of the Wilderness Therapy Treatment Process in Adolescent Mental Health Care in Norway

2018

Wilderness therapy has the potential to meet the specific needs of the current adolescent population by providing a rather unique outdoor group treatment. Wilderness therapy is not a new approach to mental health treatment, but its theoretical basis is not yet clearly delineated, in part because of the diversity found across programs and contexts. This article presents a critical realist exploration of a wilderness therapy program that was recently implemented as part of adolescent mental health services in Southern Norway. In this study, we combine fieldwork and interviews for an in-depth investigation of the treatment process, where the objective was to acquire a deeper understanding of t…

MalePsychotherapistAdolescentmedia_common.quotation_subjectCritical realism (philosophy of the social sciences)Interviews as Topic03 medical and health sciences0302 clinical medicineAgency (sociology)HumansWilderness therapy030212 general & internal medicinemedia_common030504 nursingNorwayPublic Health Environmental and Occupational HealthMental healthPsychotherapyDistressWildernessAdolescent Health ServicesWell-beingFemale0305 other medical sciencePsychologyPsychosocialDiversity (politics)Qualitative Health Research
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