Search results for "being"
showing 10 items of 1477 documents
The course of fatigue in patients with gynecologic and breast cancer
2013
Objective: The objective of this study is to examine the course of fatigue in female cancer patients during the first months after treatment. Methods: We examined a sample of 110 patients suffering from gynecological or breast cancer. Fatigue was assessed with two questionnaires, the Multidimensional Fatigue Inventory (MFI) and the fatigue scale of the quality of life questionnaire European Organisation for Research and Treatment of Cancer (EORTC QLQ-C30). Participants were tested during their stay in the hospital (t1), two weeks after discharge (t2), and three months after discharge (t3). Results: Fatigue in the patients’ sample was markedly higher than the general population reference val…
Changes in the subjective assessment of quality of life in Latvia and the European Union: results of European quality of life survey 2016
2019
Assessment of quality of life covers a variety of areas - economic conditions, housing, local environment, employment, education, household structure and family relations, work-life balance, health and healthcare, subjective well-being, quality of society. The assessment of quality of life does not always coincide with the macroeconomic indicators of the country, e.g. GDP. It includes a number of subjective indicators, which frequently show a different situation and trends than the macroenomic indicators. The European Quality of Life Survey (EQLS) is a tested tool of monitoring and analysing the quality of life in the EU and is seeing its fourth issue in 2016. The purpose of this article is…
AGuIX® from bench to bedside-Transfer of an ultrasmall theranostic gadolinium-based nanoparticle to clinical medicine.
2019
International audience; AGuIX® are sub-5 nm nanoparticles made of a polysiloxane matrix and gadolinium chelates. This nanoparticle has been recently accepted in clinical trials in association with radiotherapy. This review will summarize the principal preclinical results that have led to first in man administration. No evidence of toxicity has been observed during regulatory toxicity tests on two animal species (rodents and monkeys). Biodistributions on different animal models have shown passive uptake in tumours due to enhanced permeability and retention effect combined with renal elimination of the nanoparticles after intravenous administration. High radiosensitizing effect has been obser…
The use of theranostic gadolinium-based nanoprobes to improve radiotherapy efficacy
2014
International audience; A new efficient type of gadolinium-based theranostic agent (AGuIX) has recently been developed for magnetic resonance imaging (MRI)-guided radiotherapy. These new particles consist of a polysiloxane network surrounded by a number of gadolinium chelates, usually 10. Due to their small size (<5 nm), AGuIX typically exhibit biodistributions that are almost ideal for diagnostic and therapeutic purposes. For example, while a significant proportion of these particles accumulate in tumours, the remainder is rapidly eliminated by the renal route. In addition, these particles present no evidence of toxicity, in the absence of irradiation with up to 10 times the planned dose f…
Does Childhood Reading Disability or Its Continuance Into Adulthood Underlie Problems in Adult-Age Psychosocial Well-Being? A Follow-Up Study
2019
This follow-up study aimed at a better understanding of the associations of reading disability (RD) with adult-age psychosocial well-being. We compared adult-age psychosocial well-being in 48 individuals (20–39 years) with documented childhood RD but without comorbid disabilities to 37 matched controls. The associations of psychosocial well-being with childhood and adult-age reading fluency were studied in the RD group, controlling for IQ, gender and unemployment. Psychosocial well-being was assessed with commonly used self-report questionnaires. No group differences were found in psychosocial well-being. In the RD group, lower adult-age reading fluency was associated with symptoms of depre…
Reading comprehension difficulty is often distinct from difficulty in reading fluency and accompanied with problems in motivation and school well-bei…
2019
This paper examined if difficulty in reading comprehension (PISA) is distinct from difficulty in reading fluency and if the distinct types of reading difficulties are differently associated with learning motivation, school burnout, and school enjoyment. The participants were 1324 Finnish ninth graders. Findings suggested that difficulties in reading comprehension are often distinct from difficulties in reading fluency. Three reading difficulty groups were identified: (1) poor readers with both fluency and reading comprehension difficulties (n = 46, 3.5%), (2) slow readers with only fluency difficulties (n = 70, 5.3%), and (3) poor comprehenders with only reading comprehension difficulties (…
University as a workplace: searching for meaningful work
2018
Work in academia is changing, and research suggests that not all the changes are desirable. Higher education is developing in a direction heavily criticized, especially in relation to the concepts of neoliberal and academic capitalism. In this article, we explore meaningful work in a university context. Our focus lies on individual lecturers’ positive opportunities to make work meaningful and the university a better place to work for both students and faculty. We examine meaningful work as a relational phenomenon: how meaningfulness is constructed through features such as dialogue, expertise, interaction and sharing of ideas. Our empirical findings are based on analysis of qualitative and q…
Troponin I and cardiovascular risk prediction in the general population: the BiomarCaRE consortium
2016
AIMS: Our aims were to evaluate the distribution of troponin I concentrations in population cohorts across Europe, to characterize the association with cardiovascular outcomes, to determine the predictive value beyond the variables used in the ESC SCORE, to test a potentially clinically relevant cut-off value, and to evaluate the improved eligibility for statin therapy based on elevated troponin I concentrations retrospectively.METHODS AND RESULTS: Based on the Biomarkers for Cardiovascular Risk Assessment in Europe (BiomarCaRE) project, we analysed individual level data from 10 prospective population-based studies including 74 738 participants. We investigated the value of adding troponin …
Watching Online Videos at Work: The Role of Positive and Meaningful Affect for Recovery Experiences and Well-Being at the Workplace
2017
This study extends research on the relationship between hedonic and eudaimonic entertainment and its potential for recovery experiences and aspects of well-being (e.g., Rieger, Reinecke, Frischlich, & Bente, 2014). With the broad notion of what hedonic and eudaimonic media can entail, this research focused on unique affective experiences—namely, positive affect—and an expanded concept of meaningful affect (including elevation and gratitude). An online experiment with 148 full-time employees in the United States was conducted to investigate the unique role of positive and meaningful affect eliciting YouTube videos (compared to neutral control video) on recovery experiences and vitality and w…
Religione, benessere e job satisfaction: quale nesso possibile?
2022
Il presente contributo nasce dall'esigenza di approfondire il possibile nesso tra la dimensione del "sentire" religioso e quella dell'"agire" lavorativo, nel tentativo di (ri)portare la spiritualità all'interno del dibattito sociologico sul lavoro. Infatti, sebbene nel corso degli ultimi anni la letteratura sociologica ha mostrato come la qualità del lavoro sia un concetto multidimensionale e dinamico, la dimensione religiosa e/o spirituale del lavoratore non ha trovato adeguato spazio nella definizione di qualità del lavoro o negli interventi a suo favore. Attraverso la differenziazione dei concetti quali religiosità, spiritualità e soddisfazione sul lavoro, si giunge alla conclusione che …