Search results for "benzodiazocine"

showing 5 items of 5 documents

A facile synthesis of 1-ethyl-3-methyl-11-phenyl-1,4-dihydro-5H-pyrazolo[3,4-c][1,5]benzodiazocin-5-ones.A new ring system.

2007

Comparative studies of the Pschorr reaction in the pyrazole series. Access to the new dibenzo[e,g]pyrazolo[1,5-a][1,3]diazocine system of pharmaceuti…

2008

The diazonium tetrafluoroborate 11 obtained from 2-amino-N-methyl-N-(1-phenyl-3- methylpyrazol-5-yl)benzamide was transformed in dry acetonitrile via an ionic or radical pathway. Differences were observed with respect to ionic or radical transformations in aqueous media of the analogous diazonium hydrogen sulfate 1 derived from the same amine. In acetonitrile solution, the ionic pathway was characterized by an increased yield of 1,4-dimethyl- 3-phenyl-pyrazolo(3,4-c)isoquinolin-5-one 4 and by the formation of its isomer, the new derivative 7,9-dimethyldibenzo(e,g)pyrazolo(1,5-a)(1,3)diazocin-10(9H)-one 12. When the reaction followed a radical pathway, the pyrazolo(3,4-c)isoquinoline derivat…

Tetrafluoroborate1Ionic bonding4-pyrazolyl transferPyrazoleMedicinal chemistrylcsh:QD241-441chemistry.chemical_compoundlcsh:Organic chemistryPyrazolo[3Organic chemistry4-c]isoquinolineIsoquinolineAcetonitrileBenzamidePyrazolodibenzodiazocinePschorr reactionpyrazolo(34-c)isoquinolinepyrazolodibenzodiazocine14-pyrazolyl transfer X-ray structure14-pyrazolyl transfer; Pschorr reaction; Pyrazolodibenzodiazocine; Pyrazolo[34-c]isoquinoline; X-ray structureOrganic ChemistryPschorr reactionSettore CHIM/08 - Chimica FarmaceuticachemistryPschor reaction pyrazolo[34-c]isoquinoline pyrazolodibenzodiazocine 14- pyrazolyl transfer X-ray structureAmine gas treatingX-ray structureDerivative (chemistry)

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A facile synthesis of 1-ethyl-3-methyl-11-phenyl-1,4-dihydro-5H-pyrazolo[3,4-c][1,5]benzodiazocin-5-ones. A new ring system

2007

The new ring system pyrazolo[3,4-c][1,5]benzodiazocine was obtained through cyclization of the key intermediate of type 6a-d and 9, in refluxing toluene in presence of a catalytic amount of p-toluensulfonic acid, from moderate to high yields

15-benzodiazocinePyrazolo-15-benzodiazocinePyrazoleAntitumor activity

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CCDC 1546698: Experimental Crystal Structure Determination

2017

Related Article: Adam F. Henwood, Amlan K. Pal, David B. Cordes, Alexandra M. Z. Slawin, Thomas W. Rees, Cristina Momblona, Azin Babaei, Antonio Pertegás, Enrique Ortí, Henk J. Bolink, Etienne Baranoff, Eli Zysman-Colman|2017|J.Mater.Chem.C|5|9638|doi:10.1039/C7TC03110F

Space GroupCrystallographyCrystal SystemCrystal StructureCell ParametersExperimental 3D Coordinates(510-dihydrodiimidazo[12-b:2'1'-d][25]benzodiazocine)-(26-dimethoxy-5-[5-(trifluoromethyl)pyridin-2-yl]pyrimidin-3-ium-4-yl)-(26-dimethoxy-5-[5-(trifluoromethyl)pyridin-2-yl]pyrimidin-4-yl)-iridium (510-dihydrodiimidazo[12-b:2'1'-d][25]benzodiazocine)-bis(26-dimethoxy-5-[5-(trifluoromethyl)pyridin-2-yl]pyrimidin-4-yl)-iridium tris(hexafluorophosphate) acetonitrile diethyl ether solvate

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CCDC 1546697: Experimental Crystal Structure Determination

2017

Space GroupCrystallographyCrystal SystemCrystal StructureCell Parameters(510-dihydrodiimidazo[12-b:2'1'-d][25]benzodiazocine)-(26-dimethoxy-5-[4-methylpyridin-2-yl]pyrimidin-4-yl)-(26-dimethoxy-5-[4-methylpyridin-2-yl]pyrimidin-3-ium-4-yl)-iridium bis(hexafluorophosphate) acetonitrile diethyl ether solvateExperimental 3D Coordinates

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