Search results for "bond"

Synergistic photo-release of drugs by non-linear excitation

2014

ABSTRACTNanomaterials engineered in novel multi-modular systems in which every component works in a synergistic way with others could potentially lead to a completely new type of tools for nanomedicine. The development of nanostructures able to release drugs directly within the target after a stimulus can drastically improve the therapeutics efficiency by reducing side effects. Gold nanoparticles offer one of the most suitable platforms for the development of modular nano-devices. On the one hand, their surface properties enable effective coating by peptides containing at least one cysteine, thus yielding stable and non-cytotoxic systems. On the other, their intriguing photophysics, charact…

Stability, electronic structure, and optical properties of protected gold-doped silver Ag29−xAux (x = 0–5) nanoclusters

2017

In this work, we used density functional theory (DFT) and linear response time-dependent DFT (LR-TDDFT) to investigate the stability, electronic structure, and optical properties of Au-doped [Ag29-xAux(BDT)12(TPP)4]3- nanoclusters (BDT: 1,3-benzenedithiol; TPP triphenylphosphine) with x = 0-5. The aim of this work is to shed light on the most favorable doped structures by comparing our results with previously published experimental data. The calculated relative energies, ranging between 0.8 and 10 meV per atom, indicate that several doped Ag29-xAux nanoclusters are likely to co-exist at room temperature. However, only the Au-doped [Ag29-xAux(BDT)12(TPP)4]3- nanoclusters that have direct bon…

4,4'-[Thiophene-2,5-diylbis(ethyne-2,1-diyl)]dibenzonitrile

2008

In the solid state, the title compound, C(22)H(10)N(2)S, forms centrosymmetric dimers by pairs of non-classical C-H⋯S hydrogen bonds linking approximately coplanar mol-ecules. The benzene ring involved in this inter-action makes a dihedral angle of only 7.21 (16)° with the thio-phene ring, while the other benzene ring is twisted somewhat out of the plane, with a dihedral angle of 39.58 (9)°. The hydrogen-bonded dimers stack on top of each other with an inter-planar spacing of 3.44 Å. C-H⋯N hydrogen bonds link together stacks that run in approximately perpendicular directions. Each mol-ecule thus inter-acts with 12 adjacent mol-ecules, five of them approaching closer than the sum of the van …

Covalent Protein Binding of Vinyl Chloride Metabolites During Co-Incubation of Freshly Isolated Hepatocytes and Hepatic Sinusoidal Cells of Rats

1983

Proteins of isolated rat hepatic sinusoidal cells incubated with 14C-vinyl chloride, rat liver microsomes and an NADPH-regenerating system were alkylated by vinyl chloride metabolites formed by microsomes. This suggests that reactive vinyl chloride metabolites can penetrate sinusoidal cells. Protein alkylation in isolated hepatic sinusoidal cells was higher when these were co-incubated with isolated hepatocytes, indicating that reactive vinyl chloride metabolites formed by hepatocytes are stable enough to diffuse out of hepatocytes into sinusoidal cells. Glutathione added to the incubation medium inhibited the covalent protein binding of vinyl chloride metabolites in sinusoidal cells as wel…

Speciation of dimethyltin(IV) – and trimethyltin(IV) – carbocysteinate and – glutamate systems in aqueous media

2008

The formation of complex species in the dimethyltin(IV) and trimethyltin(IV)-carboxymethyl-L-cysteinate (carbocysteinate) systems in NaClaq, at different ionic strengths, and in a multicomponent Na+, K+, Ca2+, Mg2+, Cl- and SO42- medium representative of the seawater major composition, is discussed. Experimental results give evidence for the formation of the following species (L¼carbocysteinate): [(CH3)2Sn(L)]0, [(CH3)2Sn(HL)]+, [(CH3)2Sn(OH)(L)]-, [(CH3)2Sn(OH)2(L)]2- in the DMT–CCYS system, and [(CH3)3Sn(HL)]0, [(CH3)3Sn(L)]- and [(CH3)3Sn(OH)(L)]2- in the TMT-CCYS system. The ionic strength dependence of formation constants was taken into account by an extended Debye Huckel type equation…

[60]Fullerene l -Amino Acids and Peptides: Synthesis under Phase-Transfer Catalysis Using a Phosphine–Borane Linker. Electrochemical Behavior

2017

International audience; A new method to link amino acid and peptide derivatives to [60]fullerene is described. It uses hydrophosphination with a secondary phosphine borane. First, the stereoselective synthesis of secondary phosphine borane amino acid derivatives was achieved by alkylation of phenylphosphine borane with gamma-iodo-alpha-amino ester reagents under phase transfer catalysis (PTC). Second, a sec-phosphine borane amino ester was saponified and coupled with alpha,gamma-diamino esters to afford the corresponding dipeptide derivatives in good yields. Finally, the hydrophosphination reaction of [60]fullerene by the sec-phosphine borane compounds was performed under PTC to obtain C-60…

The parental bond, resistance to peer influence and risky driving in adolescence

2014

The present study examined the relations between gender, the parental bond, resistance to peer influence, and risky driving. In particular, the mediating role of resistance to peer pressure in the relationship between parental bond and risky driving was examined. The moderating role of gender on these associations was also investigated. The sample comprised 322 adolescents (136 males and 186 females), aged from 16 to 20 years, who were living in northern Italy. Path analysis results showed that the maternal bond only indirectly influenced adolescents’ risky driving, via resistance to peer influence. On the contrary, the paternal bond was neither directly nor indirectly associated with risky…

Nuorten tietokone- ja konsolipelaaminen ja vanhempien rooli : WHO-Koululaistutkimus

2017

TIIVISTELMÄ Nuorten tietokone- ja konsolipelaaminen ja vanhempien rooli, WHO-Koululaistutkimus Laura Miettinen Terveyskasvatuksen Pro gradu -tutkielma Jyväskylän yliopisto, Liikuntatieteellinen tiedekunta 2017 75 sivua, 22 liitettä Ohjaaja TtT Raili Välimaa Pro gradu -tutkielmassa tarkasteltiin koulupäivisin ja viikonloppuisin pelaamiseen käytetyn ajan vaihtelua sukupuolen, luokkatason, koetun äidin ja isän valvonnan, koetun äidin ja isän kiintymyssuhteen ja perheeseen liittyvien tekijöiden mukaan. Lisäksi tarkasteltiin oireiden kokemisen yleisyyttä pelaamiseen käytetyn ajan suhteen 5-, 7- ja 9-luokkalaisilla pojilla ja tytöillä. Perheeseen liittyviä tekijöitä olivat nuoren internetin käytt…

Dwurodzicielstwo: ojcostwo uczestniczące

2021

The relationship between maternal-fetus attachment and perceived parental bonds in pregnant women: Considering a possible mediating role of psycholog…

2023

Maternal-Fetal Attachment (MFA) delineates the emotional, cognitive, and behavioral aspects that mothers develop toward the unborn baby during pregnancy. The literature indicates that optimal attachment in pregnancy represents a protective factor for the mother-child attachment bond after birth and child development outcomes. To date, there are few studies that have investigated associated factors of MFA. This study sets out to explore the association between perceived parental bonds and maternal-fetal bonding in pregnant women, accounting for factors such as psychological distress, socio-demographic and obstetric characteristics.MethodsIn this cross-sectional study, 1,177 pregnant women an…