Search results for "bone"

Human interleukin-6 facilitates hepatitis B virus infection in vitro and in vivo.

2000

Abstract Background and aim. Research on hepatitis B virus (HBV) infection in vivo has been limited due to the absence of a suitable animal model. We have developed a human–mouse radiation chimera in which normal mice, preconditioned by lethal total body irradiation and radioprotected with SCID mouse bone marrow cells, are permissive for engraftment of human hematopoietic cells and solid tissues. This resulting human–mouse model, which comprises three genetically disparate sources of tissue, is therefore termed Trimera. This study was aimed at assessing the effect of human IL-6 on HBV infection in vivo in Trimera mice. Methods. Trimera mice were transplanted with human liver tissue fragment…

Nuclear receptor NR5A2 and bone: gene expression and association with bone mineral density

2011

El pdf del artículo es el manuscrito de autor (PMCID: PMC3682472).-- et al.

The Endovascular Management of an Iatrogenic Superior Gluteal Artery Rupture Following Bone Marrow Biopsy

2017

We herein report an uncommon case of a life-threatening retroperitoneal hematoma after a bone marrow biopsy. Two hours after iliac crest bone harvesting, the patient experienced syncope and severe hypotension. Urgent contrast-enhanced computed tomography demonstrated extravasation from the superior gluteal artery. Transcatheter coil embolization was performed successfully, without complications. Life-threatening complications caused by retroperitoneal bleeding after bone marrow biopsy are very rare. There are few reports on the use of endovascular treatment in the management of life-threatening hemorrhagic complications after bone marrow biopsy.

De Bibracte à Augustodunum : permanences et évolutions des activités manufacturières de l’époque gauloise à la fin du Haut-Empire

2007

L’importance de l’artisanat autunois et son développement jusqu’au iiie siècle prennent racine à Bibracte qui a su exploiter les ressources naturelles de son environnement et parfaire un savoir-faire local ayant survécu à la conquête. Les recherches sur ces activités manufacturières menées conjointement à Bibracte et à Autun nous offrent ainsi une opportunité d’étudier ces problématiques sur la durée. À Bibracte, puis à Autun, les artisans du métal sont omniprésents, mais d’autres métiers, aux témoins plus discrets, ont pu aussi êtres identifiés. Dans le cadre de cet article, nous présentons succinctement les lieux de production et un bilan des différents corps de métier. Enfin, nous évoquo…

Prevalence of relative energy deficiency in sport among well-trained male Norwegian cyclists and long-distance runners

2016

Masteroppgave i idrettsvitenskap - Universitetet i Agder 2016 Introduction Relative Energy Deficiency in Sport (RED-S) links low and reduced energy availability (EA) with negative health and performance consequences, though not well investigated in male endurance athletes. The aim of this study was to investigate the prevalence of RED-S and associated health consequences in well-trained male endurance athletes. Methods Forty-one subjects, cyclists (n=21) and runners (n=20) [age: 40 (31-45) years; BMI: 23.5 (21.4-24.0) kg/m2; body-fat: 14.0% (10.0-16.5%); training volume: 12 (9-16) h/week presented as median + interquartile range] were recruited. Protocol included assessment of bone health, …

Prevalence and associations of injury and illness among high school elite sport-students in the south of Norway

2018

Master's thesis Sports Science ME517 - University of Agder 2018 Introduction Youth participating in sports are often associated with a healthy lifestyle, however illness and injuries are frequently reported in sports. The aims for this master thesis were; (1) to examine the prevalence of sport injuries and illnesses among elite sport students at high school with regard to sport group and (2) to examine anthropometry, bone health, performance variables, energy availability and sleep time with associations to sport injuries and illness prevalence in the same sample. Methods Thirty-six high school elite sport students, endurance athletes (n=24) and ball game athletes (n=12) [age: 16.3±0.2 year…

MiR-33a Controls hMSCS Osteoblast Commitment Modulating the Yap/Taz Expression Through EGFR Signaling Regulation

2019

Mesenchymal stromal cells (hMSCs) display a pleiotropic function in bone regeneration. The signaling involved in osteoblast commitment is still not completely understood, and that determines the failure of current therapies being used. In our recent studies, we identified two miRNAs as regulators of hMSCs osteoblast differentiation driving hypoxia signaling and cytoskeletal reorganization. Other signalings involved in this process are epithelial to mesenchymal transition (EMT) and epidermal growth factor receptor (EGFR) signalings through the regulation of Yes-associated protein (YAP)/PDZ-binding motif (TAZ) expression. In the current study, we investigated the role of miR-33a family as a (…

The osteogenic potential of physical activity

2022

Les ossements animaux

2007

The importance of fracture-healing on the deformation of fluid-filled layered systems

2014

International audience; Understanding the fracturingehealingerefracturing cycle is a fundamental part of studying the deformation dynamics and the permeability evolution of rock systems. Previous studies, however, have not examined the influence of healing i.e. fracture-closure through vein formation and the mechanical properties of the " healed " fractures (veins) on the rock deformation. We present results from a two-dimensional coupled hydro-mechanical model which simulates large time and spatial scale dynamic fracturing and healing of a porous medium under the influence of gravity, tectonic stretching and elevated fluid pressures. Our results show that healing decreases the local porosi…