Search results for "bowel"
showing 10 items of 637 documents
Impact of BMGIM Music Therapy on Emotional State in Patients with Inflammatory Bowel Disease: A Randomized Controlled Trial
2021
Este artículo se encuentra disponible en la siguiente URL: https://www.mdpi.com/2077-0383/10/8/1591 En este artículo de investigación también participan: María Josefa-Rodríguez-Morales, Ana Monzó-Gallego, José Luis Platero Armero y José Enrique de la Rubia Ortí. Este artículo pertenece al número especial "Novel Insight into the Diagnosis and Management of Crohn?s Disease". Background. Patients with inflammatory bowel disease (IBD) have a high prevalence of emotional disturbances which worsen the symptoms of the disease. As a therapeutic alternative that is part of a comprehensive care alongside medication, the Bonny Method of Guided Imagery and Music (BMGIM) music-assisted therapy has achie…
ROLE OF RENIN-ANGIOTENSIN SYSTEM IN COLONIC DYSMOTILITY ASSOCIATED WITH BOWEL INFLAMMATION IN RATS
2015
Dysregulation of different mediator systems could contribute to the gut dismotility in inflammatory bowel diseases (IBDs), chronic disorders characterized by an exasperated immune response disturbing gut functions. Among these, Angiotensin II (Ang II), the main peptide of renin-angiotensin system (RAS), can participate in inflammatory responses and RAS components are increased in IBD patients. Since RAS has emerged as gut motility regulator, our objectives was to investigate, in an IBD rat model, the RAS functionality and its eventual contribution to colonic dismotility. Experimental colitis was induced in rats by intracolonic administration of 2,4-dinitrobenzenesulfonic acid (DNBS). Drug e…
New actors in the gut :emerging players in motility and in inflammatory bowel diseae
2017
Gastrointestinal motility is an integrated process generated and modulated by local and circulating hormones and neurotransmitters which act and interact directly and indirectly on muscle cells. A plethora of regulators have been identified, but this field is continuously in expansion. Among the new actors in gut accumulating evidence strongly supports a role of renin-angiotensin system (RAS) in the digestive tract cooperating with other major mediators for maintaining gastrointestinal homeostasis. Transcripts encoding RAS components were detected in gastrointestinal tract and the involvement of RAS in gut motility modulation is increasingly emerging. The available literature demonstrated t…
Telemedicine Is an Effective Tool to Monitor Disease Activity in IBD Patients in the COVID-19 Era: A Single Centre Experience Based on Objective Data
2022
Background: The COVID-19 outbreak has led IBD clinics to adopt a remote monitoring approach in order to guarantee an adequate follow-up of patients with inflammatory bowel disease (IBD) and ensure the rules of social distancing. Aim: The aim of the study was to perform a survey on IBD patients who underwent remote monitoring in our tertiary referral center, to assess adherence, patients’ perceptions and satisfaction, and finally their opinions for future monitoring. Furthermore, we evaluated changes in disease activity and Quality of Life (QoL) using validated questionnaires. Methods: Consecutive patients with IBD scheduled for follow-up visits were switched to remote monitoring throu…
The Administration of Escherichia coli Nissle 1917 Ameliorates Development of DSS-Induced Colitis in Mice
2018
The beneficial effects of probiotics on immune-based pathologies such as inflammatory bowel disease (IBD) have been well reported. However, their exact mechanisms have not been fully elucidated. Few studies have focused on the impact of probiotics on the composition of the colonic microbiota. The aim of the present study was to correlate the intestinal anti-inflammatory activity of the probiotic Escherichia coli Nissle 1917 (EcN) in the dextran sodium sulfate (DSS) model of mouse colitis with the changes induced in colonic microbiota populations. EcN prevented the DSSinduced colonic damage, as evidenced by lower disease activity index (DAI) values and colonic weight/length ratio, when compa…
Incidence and Management of Recurrence in Patients with Crohn's Disease Who Have Undergone Intestinal Resection: The Practicrohn Study.
2017
Background: More than 50% of patients with Crohn's disease require intestinal resection at least once. Postoperative recurrence (POR) is almost uniform if prophylactic treatment is not started early. Endoscopic monitoring is generally advised. We studied the incidence and management of recurrence in patients who had undergone intestinal resection. Methods: Practicrohn was an observational retrospective study performed in 26 Spanish hospitals including patients aged >= 18 years who underwent Crohn's disease-related ileocolonic resection between January 2007 and December 2010. We recorded preventive treatments, the incidence of clinical recurrence in daily practice, and associated risk factor…
Impact of Oat-Based Products on Human Gastrointestinal Tract
2015
Abstract Oat is rich in valuable nutrients. In comparison to other cereals, oat contains more total proteins, carbohydrate, fat, non-starch fibre, as well as unique antioxidants (one of them - avenanthramides), vitamins, and minerals. One of the most often studied components of oats is β-glucan - a type of soluble dietary fibre located throughout the starch endosperm, but with highest concentration in the bran. Many studies have shown the beneficial health effects of oat β-glucan as a soluble dietary fibre. Until now, most of the studies on this nutrient have been conducted in the cardiovascular and diabetology field. This article aimed to review the literature on studies that investigated …
Variability of the human gut microbiota in space, time, and associated with the irritable bowel syndrome
2013
Esta tesis doctoral se centra en el estudio de una de las comunidades microbianas más complejas y de mayor interés biomédico: la microbiota asociada al intestino distal de humanos. El objetivo principal ha sido estudiar las alteraciones potenciales de la microbiota intestinal en relación con el síndrome del intestino irritable (SII), el desorden funcional del tracto gastrointestinal más común en sociedades occidentales. Nuestra aproximación forma parte de una visión actual sobre las relaciones entre microorganismos y hospedadores que trasciende la clásica y estrecha mirada sobre patógenos concretos y enfermedades infecciosas y la desplaza hacia una concepción más de conjunto, que valora los…
Role of the IL-23/IL-17 Pathway in Rheumatic Diseases: An Overview
2021
Interleukin-23 (IL-23) is a pro-inflammatory cytokine composed of two subunits, IL-23A (p19) and IL-12/23B (p40), the latter shared with Interleukin-12 (IL-12). IL-23 is mainly produced by macrophages and dendritic cells, in response to exogenous or endogenous signals, and drives the differentiation and activation of T helper 17 (Th17) cells with subsequent production of IL-17A, IL-17F, IL-6, IL-22, and tumor necrosis factor α (TNF-α). Although IL-23 plays a pivotal role in the protective immune response to bacterial and fungal infections, its dysregulation has been shown to exacerbate chronic immune-mediated inflammation. Well-established experimental data support the concept that IL-23/IL…
B lymphocyte intestinal homing in inflammatory bowel disease.
2011
Abstract Background Inflammatory bowel disease (IBD) is thought to be due to an abnormal interaction between the host immune system and commensal microflora. Within the intestinal immune system, B cells produce physiologically natural antibodies but pathologically atypical anti-neutrophil antibodies (xANCAs) are frequently observed in patients with IBD. The objective is to investigate the localisation of immunoglobulin-producing cells (IPCs) in samples of inflamed intestinal tissue taken from patients with IBD, and their possible relationship with clinical features. Methods The IPCs in small intestinal, colonic and rectal biopsy specimens of patients with IBD were analysed by means of immun…