Search results for "bp"
showing 10 items of 672 documents
Freeze-out radii extracted from three-pion cumulants in pp, p–Pb and Pb–Pb collisions at the LHC
2014
In high-energy collisions, the spatio-temporal size of the particle production region can be measured using the Bose-Einstein correlations of identical bosons at low relative momentum. The source radii are typically extracted using two-pion correlations, and characterize the system at the last stage of interaction, called kinetic freeze-out. In low-multiplicity collisions, unlike in high-multiplicity collisions, two-pion correlations are substantially altered by background correlations, e.g. mini-jets. Such correlations can be suppressed using three-pion cumulant correlations. We present the first measurements of the size of the system at freeze-out extracted from three-pion cumulant correl…
Nuclear reorganization and dynamics during canine parvovirus infection
2007
Komunikācijas zinātnes doktorantu sekcija: Kopsavilkumi : 2021. gada 17. februāris
2021
IFI16 expression is related to selected transcription factors during B-cell differentiation
2015
The interferon-inducible DNA sensor IFI16 is involved in the modulation of cellular survival, proliferation, and differentiation. In the hematopoietic system, IFI16 is consistently expressed in the CD34+ stem cells and in peripheral blood lymphocytes; however, little is known regarding its regulation during maturation of B- and T-cells. We explored the role of IFI16 in normal B-cell subsets by analysing its expression and relationship with the major transcription factors involved in germinal center (GC) development and plasma-cell (PC) maturation.IFI16mRNA was differentially expressed in B-cell subsets with significant decrease inIFI16mRNA in GC and PCs with respect to naïve and memory subs…
A twofold commodification of 'place' in hotel websites and its consequences for the discursive creation of a tourist identity.
2016
Tourism is a global cultural industry and one of the world’s largest international trades (Thurlow & Jaworski, 2011). As far as tourism is understood as an agent and channel of globalisation (Pritchard & Jaworski, 2005), it makes sense to investigate it from a critical perspective and analyse how its discourse shapes the tourist experience. The aim of this study is to explore ways in which hotel websites project a place identity for the hotel and, in doing so, for the town or city in which the hotel is located. I will ask how, and in what ways, this representation relies on socio-cultural conventions, which in turn may influence the discursive construction of the social actor “tourist”. Usi…
RNA-Binding Proteins as Epigenetic Regulators of Brain Functions and Their Involvement in Neurodegeneration.
2022
A central aspect of nervous system development and function is the post-transcriptional regulation of mRNA fate, which implies time- and site-dependent translation, in response to cues originating from cell-to-cell crosstalk. Such events are fundamental for the establishment of brain cell asymmetry, as well as of long-lasting modifications of synapses (long-term potentiation: LTP), responsible for learning, memory, and higher cognitive functions. Post-transcriptional regulation is in turn dependent on RNA-binding proteins that, by recognizing and binding brief RNA sequences, base modifications, or secondary/tertiary structures, are able to control maturation, localization, stability, and tr…
Rīcībpolitikas ieviešanas izpēte - azartspēļu gadījums
2019
Bakalaura darba tēma “Rīcībpolitikas ieviešanas izpēte – azartspēļu gadījums”. Darba mērķis ir izpētīt azartspēļu nozari, analizēt kādus rīcībpolitikas instrumentus Latvijas valdība ir izmantojusi, lai samazinātu azartspēļu biznesa izplatību valsts teritorijā, un analizēt, kā tā veidojusies attiecīgajā jomā. Darba mērķis ir aplūkot šīs nozares darbību laika posmā no 2006. līdz 2018. gadam. Bakalaura darba teorētiskajā daļā tiek aplūkota rīcībpolitikas jēdziena definīcija, aprakstītas analīzes formas un ieviešanas modeļi. Tiks apskatīta arī azartspēļu jēdziena definīcija, azartspēļu vēsture, un azartspēļu atkarības problēmas veidošanās, kā arī tiks aplūkota Latvijas azartspēļu regulēšana. Ba…
Curcumin and Andrographolide Co-Administration Safely Prevent Steatosis Induction and ROS Production in HepG2 Cell Line
2023
Non-alcoholic fatty liver disease (NAFLD) is an emerging chronic liver disease worldwide. Curcumin and andrographolide are famous for improving hepatic functions, being able to reverse oxidative stress and release pro-inflammatory cytokines, and they are implicated in hepatic stellate cell activation and in liver fibrosis development. Thus, we tested curcumin and andrographolide separately and in combination to determine their effect on triglyceride accumulation and ROS production, identifying the differential expression of genes involved in fatty liver and oxidative stress development. In vitro steatosis was induced in HepG2 cells and the protective effect of curcumin, andrographolide, and…
Regulation of raft-derived endocytic pathways : studies on echovirus 1 and baculovirus
2009
Elina Kakkonen tutki väitöskirjassaan kahden erilaisen viruksen, echovirus 1:n ja bakuloviruksen soluun sisäänmenon reittejä ja säätelijöitä. Echovirus 1 (EV1) on ihmisiä infektoiva pikornavirus, joka voi aiheuttaa esimerkiksi aivokalvontulehdusta, sydänlihastulehdusta sekä lievempiä hengitystieinfektioita. Bakulovirus puolestaan on ihmisille vaaraton, hyönteisiä infektoiva virus, joka on osoittautunut lupaavaksi geeninsiirtokuljettajaksi geeniterapiassa.Virukset voivat käyttää soluun tunkeutumisessaan hyväkseen soluissa valmiina olevia erilaisia reittejä, joita solut itse tarvitsevat esimerkiksi ravintoaineiden sisäänottoon. Näin virukset pääsevät solun sisälle solun oman koneiston kuljett…
Local regularity estimates for general discrete dynamic programming equations
2022
We obtain an analytic proof for asymptotic H\"older estimate and Harnack's inequality for solutions to a discrete dynamic programming equation. The results also generalize to functions satisfying Pucci-type inequalities for discrete extremal operators. Thus the results cover a quite general class of equations.