Search results for "brain tumor"

Fusingin vivoandex vivoNMR sources of information for brain tumor classification

2011

In this study we classify short echo-time brain magnetic resonance spectroscopic imaging (MRSI) data by applying a model-based canonical correlation analyses algorithm and by using, as prior knowledge, multimodal sources of information coming from high-resolution magic angle spinning (HR-MAS), MRSI and magnetic resonance imaging. The potential and limitations of fusing in vivo and ex vivo nuclear magnetic resonance sources to detect brain tumors is investigated. We present various modalities for multimodal data fusion, study the effect and the impact of using multimodal information for classifying MRSI brain glial tumors data and analyze which parameters influence the classification results…

Comment on “Computer-Extracted Texture Features to Distinguish Cerebral Radionecrosis from Recurrent Brain Tumors on Multiparametric MRI: A Feasibili…

2017

We have read with great interest the article published by Tiwari et al, “Computer-Extracted Texture Features to Distinguish Cerebral Radionecrosis from Recurrent Brain Tumors on Multiparametric MRI: A Feasibility Study.”[1][1] In their article, they refer to our work regarding brain metastasis

New Hope in Brain Glioma Surgery: The Role of Intraoperative Ultrasound. A Review

2018

Maximal safe resection represents the gold standard for surgery of malignant brain tumors. As regards gross-total resection, accurate localization and precise delineation of the tumor margins are required. Intraoperative diagnostic imaging (Intra-Operative Magnetic Resonance-IOMR, Intra-Operative Computed Tomography-IOCT, Intra-Operative Ultrasound-IOUS) and dyes (fluorescence) have become relevant in brain tumor surgery, allowing for a more radical and safer tumor resection. IOUS guidance for brain tumor surgery is accurate in distinguishing tumor from normal parenchyma, and it allows a real-time intraoperative visualization. We aim to evaluate the role of IOUS in gliomas surgery and to ou…

Neuro-radiosurgery treatments: MRI brain tumor seeded image segmentation based on a cellular automata model

2016

Gross Tumor Volume (GTV) segmentation on medical images is an open issue in neuro-radiosurgery. Magnetic Resonance Imaging (MRI) is the most promi-nent modality in radiation therapy for soft-tissue anatomical districts. Gamma Knife stereotactic neuro-radiosurgery is a mini-invasive technique used to deal with inaccessible or insufficiently treated tumors. During the planning phase, the GTV is usually contoured by radiation oncologists using a manual segmentation procedure on MR images. This methodology is certainly time-consuming and op-erator-dependent. Delineation result repeatability, in terms of both intra- and inter-operator reliability, is only obtained by using computer-assisted appr…

Intraoperative DNA methylation classification of brain tumors impacts neurosurgical strategy

2021

Abstract Background Brain tumor surgery must balance the benefit of maximal resection against the risk of inflicting severe damage. The impact of increased resection is diagnosis-specific. However, the precise diagnosis is typically uncertain at surgery due to limitations of imaging and intraoperative histomorphological methods. Novel and accurate strategies for brain tumor classification are necessary to support personalized intraoperative neurosurgical treatment decisions. Here, we describe a fast and cost-efficient workflow for intraoperative classification of brain tumors based on DNA methylation profiles generated by low coverage nanopore sequencing and machine learning algorithms. Met…

Coplanar Indirect-Navigated Intraoperative Ultrasound: Matching Un-navigated Probes With Neuronavigation During Neurosurgical Procedures. How We Do I…

2021

BACKGROUND Intraoperative ultrasound (IOUS) is becoming more and more adopted in neurosurgery, since it has been associated to greater extent of resection (EOR) and to gross total resection (GTR) during brain tumor surgery. IOUS main limitations are spatial resolution, width and orientation of the field of view and scan quality, which are operator-dependent. Furthermore, most neurosurgeons are not confident with this technique, which needs a long learning curve in order to identify and interpret anatomic structures. OBJECTIVE To describe an effective procedure to take advantages of both IOUS and neuronavigation in case of lack of a navigated ultrasound system. METHODS We propose a reliable …

Clinical support in radiation therapy scenarios: MR brain tumor segmentation using an unsupervised fuzzy C-Means clustering technique

2016

NeXt for neuro-radiosurgery: A fully automatic approach for necrosis extraction in brain tumor MRI using an unsupervised machine learning technique

2017

Stereotactic neuro-radiosurgery is a well-established therapy for intracranial diseases, especially brain metastases and highly invasive cancers that are difficult to treat with conventional surgery or radiotherapy. Nowadays, magnetic resonance imaging (MRI) is the most used modality in radiation therapy for soft-tissue anatomical districts, allowing for an accurate gross tumor volume (GTV) segmentation. Investigating also necrotic material within the whole tumor has significant clinical value in treatment planning and cancer progression assessment. These pathological necrotic regions are generally characterized by hypoxia, which is implicated in several aspects of tumor development and gro…

Computed Tomography in Brain Tumors

1981

Craniocerebral injury and brain tumor are the two most important indications for CT studies. There is unanimous agreement that computed tomography is unequalled in its diagnostic accuracy in demonstration of intracranial tumors. Our own experience is based on observations in 3,750 patients with brain tumors or cerebral metastases who were studied in the period from December 1974 to March 1980 (Table 1). Initial CT studies demonstrated the intracranial tumor or tumors in 3,589 cases (95.7%). Several CT examinations were necessary for diagnosis of a brain tumor in 112 patients (3.0%). Other diagnostic procedures or postmortem studies revealed a brain tumor which had not been demonstrated with…

Hemostasis in brain tumor surgery using the Aquamantys system

2014

Background: Adequate hemostasis in cranial and spinal tumor surgery is of paramount importance in neurosurgical practice. Generalized ooze bleeding from the surgical walls cavity, coming from neoplastic vessels or nervous tissue, may be problematic. Recent technical advances have dramatically reduced intraoperative complications related to blood loss. Several techniques are usually employed to control hemostasis in tumor surgery, including preoperative embolization, intraoperative hypotension, electrical coagulation, and local application of fibrin sealants or hemostatic matrix, which influence coagulation. Material/Methods: Our aim in this study was to evaluate the efficacy and the safety …