Search results for "bud"
showing 10 items of 637 documents
Spatial analysis techniques for mapping the annual surface runoff in Sicily under the Budyko’s framework
2016
This work shows a new approach, based on the Budyko framework, for mapping the mean annual surface runoff and deriving the probability distribution of the annual runoff in arid and semi-arid watersheds. We analytically provide the annual runoff distribution as the derived distribution of annual rainfall and potential evapotranspiration. The simulated long-term annual runoff and its distribution have been compared with historical records at several gauged stations, obtaining satisfactory matching.
Les Républicains au Congrès
2015
En 1994, les Républicains élus à la Chambre des représentants promettaient une révolution conservatrice qui devait réduire laplace de l’État fédéral dans la société américaine. Vingt ans plus tard, ce livre dresse le bilan législatif de la longue période de domination républicaine sur la colline du Capitole pour s’interroger sur la portée de la révolution annoncée. En étudiant notamment l’impact des élus du GOP sur la politique budgétaire et les réformes, adoptées ou avortées, de l’État-Provi- dence américain, on observe un écart spectaculaire entre les paroles et les actes. Comment expliquer cet échec relatif de la révolution conservatrice? Quels obstacles éle…
Organy w kościele Świętego Krzyża w Bytomiu-Miechowicach. Historia i koncepcja rekonstrukcji
2018
Th article describes the history of organs in the noble Church of the Holy Cross in BytomMiechowice. Th largest amount of information has been preserved about the instrument built in 1905 by the Schlag und Söhne company from Świdnica. Ths organ was dismantled in the 1960s due to heavy mining damage and was later replaced by a temporary instrument. However, work is currently underway on the renovation of the temple. A proposal to recreate the historical organ is among the plans and is included in the ongoing design work.
Oro-gustatory perception of dietary lipids and calcium signaling in taste bud cells are altered in nutritionally obesity-prone Psammomys obesus.
2013
Since the increasing prevalence of obesity is one of the major health problems of the modern era, understanding the mechanisms of oro-gustatory detection of dietary fat is critical for the prevention and treatment of obesity. We have conducted the present study on Psammomys obesus, the rodent desert gerbil which is a unique polygenic natural animal model of obesity. Our results show that obese animals exhibit a strong preference for lipid solutions in a two-bottle test. Interestingly, the expression of CD36, a lipido-receptor, in taste buds cells (TBC), isolated from circumvallate papillae, was decreased at mRNA level, but remained unaltered at protein level, in obese animals. We further st…
The Lipid-Sensor Candidates CD36 and GPR120 Are Differentially Regulated by Dietary Lipids in Mouse Taste Buds: Impact on Spontaneous Fat Preference
2011
BACKGROUND: Recent studies in rodents and humans suggest that the chemoreception of long-chain fatty acids (LCFA) in oral cavity is involved in the spontaneous preference for fatty foods and might contribute to the obesity risk. CD36 and GPR120 are LCFA receptors identified in rodent taste bud cells. The fact that CD36 or GPR120 gene inactivation leads to a decrease in the preference for lipids raises the question of the respective role(s) played by these gustatory lipid-sensor candidates. METHODOLOGY/PRINCIPAL FINDINGS: Using a combination of biochemical, nutritional and behavioural studies in wild-type, CD36(+/-)and CD36(-/-) mice, it was found that: 1°) CD36 and GPR120 display different …
Cell mechanisms of gustatory lipids perception and modulation of the dietary fat preference.
2014
Dietary lipids are usually responsible of several metabolic disorders. Recent compelling evidences suggest that there is a sixth taste modality, destined for the detection of oro-gustatory fats. The lipid-binding glycoprotein CD36, expressed by circumvallate papillae (CVP) of the mouse tongue, has been shown to be implicated in oro-gustatory perception of dietary lipids. We demonstrate that linoleic acid (LA) by activating sPLA2, cPLA2 and iPLA2 via CD36, produced arachidonic acid (AA) and lyso-phosphatidylcholine (Lyso-PC) which triggered Ca(2+) influx in CD36-positive taste bud cells (TBC), purified from mouse CVP. LA induced the production of Ca(2+) influx factor (CIF). CIF, AA and Lyso-…
CD36 and taste of fat.
2012
Purpose of review This review explores the recent literature on the role of CD36 in the taste of fat, eating behavior and obesity risk in rodents and humans. Recent findings During the last decade, evidence was accumulated supporting the existence of a taste of fat responsible for the spontaneous preference for lipid-rich foods. Surprisingly, the multifunctional membrane-associated protein CD36 appears to play a significant role in this system in rodents. Recently, another plausible gustatory lipid sensor, the GPR120, was also identified in mice, revealing that the mechanism involved in oral fat detection is more complex than initially expected. Interestingly, lingual CD36 and GPR120 displa…
CD36 involvement in orosensory detection of dietary lipids, spontaneous fat preference, and digestive secretions
2005
International audience; Rats and mice exhibit a spontaneous attraction for lipids. Such a behavior raises the possibility that an orosensory system is responsible for the detection of dietary lipids. The fatty acid transporter CD36 appears to be a plausible candidate for this function since it has a high affinity for long-chain fatty acids (LCFAs) and is found in lingual papillae in the rat. To explore this hypothesis further, experiments were conducted in rats and in wild-type and CD36-null mice. In mice, RT-PCR experiments with primers specific for candidate lipid-binding proteins revealed that only CD36 expression was restricted to lingual papillae although absent from the palatal papill…
Ca2+ signaling in taste bud cells and spontaneous preference for fat: Unresolved roles of CD36 and GPR120
2013
Recent compelling evidences from rodent and human studies raise the possibility for an additional sixth taste modality devoted to oro-gustatory perception of dietary lipids. Understanding the mechanisms underlying oro-gustatory detection of dietary fat is critical for the prevention and treatment of obesity. A number of studies have suggested that lingual CD36, a glycoprotein, highly expressed by circumvallate papillae of the tongue, is implicated in the perception of dietary fat taste. G protein-coupled receptors (GPCRs) are important signaling molecules for many aspects of cellular functions. It has been shown that these receptors, particularly GPR120, are also involved in lipid taste per…
Oro-sensory perception of dietary lipids: new insights into the fat taste transduction.
2009
The sense of taste informs the organism about the quality of ingested food. Five basic taste modalities, e.g., sweet, sour, bitter, salty and umami have so far been identified. Recent compelling evidence from rodent and human studies raise the possibility for an additional sixth taste modality devoted to the perception of lipids. Recent studies strongly suggest that lingual CD36, being implicated in the perception of dietary fat, may act as a gustatory lipid sensor. Knocking down of CD36 gene decreases the spontaneous preference for long chain fatty acids (LCFA) in mice subjected to a free choice situation. Lingual CD36, after activation by LCFA, is able to trigger specific signalling mecha…