Search results for "bula"

[Drugs use in pregnancy in the Valencia Region and the risk of congenital anomalies].

2017

Background Despite the potential risks of drug use during pregnancy, consumption has increased in recent decades. Objective To identify the risk of congenital anomalies (CA) associated with the use of drugs in primary care in pregnant women resident in the Valencia Region. Methods A case-control study, considering a case as a less than one year old live birth in 2009–2010, diagnosed with a CA and resident in the Valencia Region, obtained from the CA population-based registry. Controls were selected from the Metabolic Disease Registry, and the drugs prescribed and dispensed from the Integral Management of Pharmaceutical Services. Crude odds ratio (OR) was calculated with its 95% confidence i…

Acute renal failure and liver dysfunction after subcutaneous injection of 3-sn-phosphatidylcholine (Lipostabil®)-case report.

2011

INTRODUCTION Drug-induced tubulointerstitial nephritis and acute tubular necrosis are common, and are often caused by drugs especially antibiotics or non-steroidal anti-inflammatory drugs. Drug-induced liver dysfunction and renal failure after subcutaneous injection of phosphatidylcholine was not reported so far. 3-sn-Phosphatidylcholine has been described as a cell lysis reaction-inducing drug. Its in vitro data indicated a relevant toxicity potential. In particular human cell types such as fibroblast-like preadipocytes, vascular and skeletal muscle cells, or renal epithelial cells react more sensitive than other human cell types. CASE REPORT We present a 28-year-old woman who received 3.5…

Reactivation of SNURF-SNRPN gene by DNA Methyltransferase inhibitors in a Prader-Willi lymphoblastoid cell line.

2014

"I trust the printed ones more" : Finnish upper secondary school students’ use of print and electronic dictionaries

2017

Digitalisoituvassa maailmassa myös sanakirjat siirtyvät painetusta formaatista sähköiseen. Sähköisten sanakirjojen suureen suosioon vaikuttaa varsinkin niiden käyttömukavuus ja nopeus sekä niiden painettua sanakirjaa parempi saavutettavuus myös kodin ja koulun ulkopuolella esimerkiksi älypuhelimien sanakirjasovellusten avulla. Sähköisten sanakirjojen kirjo on kuitenkin suuri, eivätkä kaikki oppijoiden käyttämät sanakirjat ole käyneet läpi minkäänlaista asiantuntija-arviointia. Tämän tutkielman tarkoituksena on selvittää suomalaisten lukiolaisten painettujen ja sähköisten englannin sanakirjojen käyttöä. Tutkielman aineisto kerättiin kyselylomakkeella, jossa kysyttiin, kuinka usein ja millais…

Drama as a method of teaching EFL vocabulary : a material package for lower secondary school teachers

2017

Perusopetuksen opetussuunnitelman perusteiden (2014) mukaan vieraan kielen opetuksessa ”leikin, laulun, pelillisyyden ja draaman avulla oppilaat saavat mahdollisuuden kokeilla kasvavaa kielitaitoaan ja käsitellä myös asenteita”. Monille vieraiden kielten opettajille draama on kuitenkin kohtuullisen vieras työkalu eikä sen sovellusmahdollisuuksia tunneta. Tämä materiaalipaketti onkin suunnattu yläkoulun englannin opettajille resurssipankiksi englannin sanaston opettamiseen draamakasvatuksen keinoja hyödyntäen. Kohderyhmäksi valikoituivat yläkouluikäiset nuoret, koska heillä on käytännön kielitaitoa jo sen verran, että he pystyvät toimimaan draamassa ja kommunikoimaan spontaanisti. Teoriaosio…

Datu transformāciju iespējas Oracle vidē

2016

Datu transformācijas ir laikietilpīgs process regulārajās ielādēs. Tām jānotiek ātri, noteiktās laika robežās. Uzņēmuma datu noliktavā tiek izstrādāts viens problēmas risinājums, nevis vairāki, izvēloties ātrdarbīgāko, tāpēc autors apskata vairākas transformāciju alternatīvas 4 problēmu risināšanai: 1. Hierarhisko datu vairāku līmeņu attēlošanai rindā; 2. Hierarhisko slēguma datu attēlošana rindā; 3. Divu vēstures tabulu apvienošana ar pārklājošiem periodiem 4. Vēstures tabulas vispārināšana, pārrēķinot sākuma un beigu datumus. Praktiskajā daļā katrai no problēmām tika atrasti/izstrādāti, aprakstīti un salīdzināti 2 – 3 risinājumi, starp kuriem noteikts ātrākais izpildes laiks attiecīgās pr…

A similar to 32-70 K FORMATION TEMPERATURE RANGE FOR THE ICE GRAINS AGGLOMERATED BY COMET 67 P/CHURYUMOV-GERASIMENKO

2015

Grand Canonical Monte Carlo simulations are used to reproduce the N$_2$/CO ratio ranging between 1.7 $\times$ 10$^{-3}$ and 1.6 $\times$ 10$^{-2}$ observed {\it in situ} in the Jupiter family comet 67P/Churyumov-Gerasimenko by the ROSINA mass spectrometer aboard the Rosetta spacecraft, assuming that this body has been agglomerated from clathrates in the protosolar nebula. Simulations are done using an elaborated interatomic potentials for investigating the temperature dependence of the trapping within a multiple guest clathrate formed from a gas mixture of CO and N$_2$ in proportions corresponding to those expected for the protosolar nebula. By assuming that 67P/Churyumov-Gerasimenko agglom…

The Adaptation of Professional Fishing to Diminished Vendace Stocks: The Case of Finnish Inland Waters

1999

Abstract The large number of lakes covering 10% of Finland's surface area provide an opportunity for both full-time and part-time professional fishing. However, the development of the fishing industry is hindered by unpredictable fluctuations in fish stocks, by the elaborate hierarchy of the fisheries system, as well as by certain features of Finnish professional fishing, such as the small size of fishing enterprises, the scattered pattern of production, and long transportation distances to the core demand areas. According to Finnish catch statistics, the stock of vendace Coregonus albula has clearly diminished since the mid 1980s. Our results show that full-time professional fishermen diff…

Lifting the Vendace, Coregonus albula, on the Life Table : Survival, Growth and Reproduction in Different Life-Stages during Very High and Low Abunda…

2021

We analyzed the variability in vendace population parameters in the context of a life table. Parameters related to growth, fecundity and survival were estimated for post-recruitment (age > 1 growing season) life stages of Lake Southern Konnevesi vendace in both very high and low population abundance regimes. Pre-recruitment survival producing population stability was then determined. We found a very strong compensatory density dependence in growth, fecundity and survival: during low abundance, a lifetime reproductive output of a female was almost 20 times that of the abundant regime. To maintain the low abundance regime, pre-recruitment survival must counterbalance it by decreasing to a ver…

Vertigo in childhood: A methodological approach

2012

Children complaints dizziness merit meticulous evaluation to differentially diagnose a vestibular disease. A syndrome mimicking certain classic signs and symptoms of adult vestibular disorders may be presents in children, such as benign paroxysmal positional vertigo, usually associated with aging. Benign paroxysmal vertigo, in which migraine is a manifestation, with sudden onset of dizziness is a rare peripheral vestibular disorder that is commonly ignored or misdiagnosed. This review covers the development of the diagnosis, evaluation and treatment approaches of vertigo of childhood, a valid support for physician that approach dizzy children (Ref. 25). Full Text in PDF www.elis.sk.