Search results for "càncer"
showing 10 items of 150 documents
IMPORTANCIA DE LA ENFERMERA ESCOLAR EN LA DETECCIÓN DE LA NEOPLASIA TESTICULAR
2011
En este artículo planteamos una revisión de la literatura en diferentes bases de datos (CINAHL, CUIDEN, MEDLINE) con el fin de valorar la importancia de la neoplasia testicular en la adolescencia y el papel fundamental del profesional de enfermería-, concretamente de la enfermera escolar, en la detección precoz de esta patología. Una vez analizado el tema y tras tomar conciencia de la importancia de enseñar prácticas de autoexploración testicular correctas, se ha concluido que la enfermera escolar no debe desarrollar únicamente una actividad asistencial, sino que entre sus funciones se debe contemplar la promoción de la salud y la prevención del cáncer testicular. Dentro del proceso educado…
Estrategias de afrontamiento en padres de niños con cáncer
2012
Se pretende conocer las estrategias de afrontamiento que utilizan los padres de niños con cáncer ante al reto que supone esta enfermedad. Se ha utilizado una metodología de investigación grupal y cualitativa. La muestra la constituyen 14 madres/padres cuyos hijos hace más de dos años que han contraído la enfermedad. Se ha comprobado que los padres utilizan una gran variedad de estrategias. Unas son activas: centrada en el problema (adecuación a la acción y calma, entereza y reflexión); regulación afectiva; búsqueda de información; adquisición de apoyo social, instrumental, informativo y/o emocional; reevaluación o reestructuración cognitiva y pensamiento positivo; y distracción. Otras son p…
Factors that influence treatment delay in patients with colorectal cancer
2016
// Irene Zarcos-Pedrinaci 1, 11 , Alberto Fernandez-Lopez 2 , Teresa Tellez 1, 11 , Francisco Rivas-Ruiz 1, 11 , Antonio Rueda A 3, 11 , Maria Manuela Morales Suarez-Varela 4 , Eduardo Briones 5 , Marisa Bare 6, 11 , Antonio Escobar 7, 11 , Cristina Sarasqueta 8, 11 , Nerea Fernandez de Larrea 9, 11 , Urko Aguirre 10, 11 , Jose Maria Quintana 10, 11 , Maximino Redondo 1, 11 and On Behalf of the CARESS-CCR Study Group 1 Research Unit, Agencia Sanitaria Costa del Sol, Marbella, Spain 2 Servicio de Cirugia, Agencia Sanitaria Costa del Sol, Marbella, Spain 3 Servicio de Oncologia Medica, Agencia Sanitaria Costa del Sol, Marbella, Spain 4 Unit of Public Health, Hygiene and Environmental Health, …
CHAIMELEON Project: Creation of a Pan-European Repository of Health Imaging Data for the Development of AI-Powered Cancer Management Tools
2022
[EN] The CHAIMELEON project aims to set up a pan-European repository of health imaging data, tools and methodologies, with the ambition to set a standard and provide resources for future AI experimentation for cancer management. The project is a 4 year long, EU-funded project tackling some of the most ambitious research in the fields of biomedical imaging, artificial intelligence and cancer treatment, addressing the four types of cancer that currently have the highest prevalence worldwide: lung, breast, prostate and colorectal. To allow this, clinical partners and external collaborators will populate the repository with multimodality (MR, CT, PET/CT) imaging and related clinical data. Subse…
Calidad sobre la Información de Salud y Cáncer en Internet.
2010
Internet es una fuente de información que cada día es utilizada por miles de personas para consultar temas de salud, y especialmente, sobre cáncer. La Conselleria de Sanitat a través del"Plan oncológico de la Comunitat Valenciana 20072010" orienta y define la política sanitaria frente al cáncer en nuestro territorio durante este periodo. Entre sus ejes de actuación básica se encuentra el apoyo al desarrollo continuado del Sistema de Información sobre Cáncer. Esta información es de gran importancia a la hora de conseguir una participación informada de la población en la toma de decisiones que afectan a su salud, contribuyendo además, a su alfabetización digital en salud, objetivo prioritario…
Prognostic implications of surgical specimen quality on the oncological outcomes of open and laparoscopic surgery in mid and low rectal cancer
2021
Abstract Purpose Determine differences in pathologic outcomes between laparoscopic (LAP) and open surgery (OPEN) for mid and low rectal cancer and its influence in long-term oncological outcomes. Methods Retrospective case matched study at a tertiary institution. Adults with rectal cancer below 12 cm from the anal verge operated between January 2005 and September 2018 were included. Primary outcomes were quality of specimen, overall survival (OS), disease-free survival (DFS), and local recurrence (LR). Results The study included 311 patients, LAP = 108 (34.7%), OPEN = 203 (65,3%). A successful resection was accomplished in 81% of the LAP group and in 84.5% of the OPEN (p = 0.505). No differ…
Characterizing the Invasive Tumor Front of Aggressive Uterine Adenocarcinoma and Leiomyosarcoma
2021
The invasive tumor front (the tumor–host interface) is vitally important in malignant cell progression and metastasis. Tumor cell interactions with resident and infiltrating host cells and with the surrounding extracellular matrix and secreted factors ultimately determine the fate of the tumor. Herein we focus on the invasive tumor front, making an in-depth characterization of reticular fiber scaffolding, infiltrating immune cells, gene expression, and epigenetic profiles of classified aggressive primary uterine adenocarcinomas (24 patients) and leiomyosarcomas (11 patients). Sections of formalin-fixed samples before and after microdissection were scanned and studied. Reticular fiber archit…
Meta-analysis of mismatch repair polymorphisms within the cogent consortium for colorectal cancer susceptibility
2013
In the last four years, Genome-Wide Association Studies (GWAS) have identified sixteen low-penetrance polymorphisms on fourteen different loci associated with colorectal cancer (CRC). Due to the low risks conferred by known common variants, most of the 35% broad-sense heritability estimated by twin studies remains unexplained. Recently our group performed a case-control study for eight Single Nucleotide Polymorphisms (SNPs) in 4 CRC genes. The present investigation is a followup of that study. We have genotyped six SNPs that showed a positive association and carried out a meta-analysis based on eight additional studies comprising in total more than 8000 cases and 6000 controls. The estimate…
Real‐world evidence of tisagenlecleucel for the treatment of relapsed or refractory large B‐cell lymphoma
2021
Abstract Tisagenlecleucel (tisa‐cel) is a second‐generation autologous CD19‐targeted chimeric antigen receptor (CAR) T‐cell therapy approved for relapsed/refractory (R/R) large B‐cell lymphoma (LBCL). The approval was based on the results of phase II JULIET trial, with a best overall response rate (ORR) and complete response (CR) rate in infused patients of 52% and 40%, respectively. We report outcomes with tisa‐cel in the standard‐of‐care (SOC) setting for R/R LBCL. Data from all patients with R/R LBCL who underwent leukapheresis from December 2018 until June 2020 with the intent to receive SOC tisa‐cel were retrospectively collected at 10 Spanish institutions. Toxicities were graded accor…
Male breast cancer in BRCA1 and BRCA2 mutation carriers: pathology data from the Consortium of Investigators of Modifiers of BRCA1/2
2016
Background BRCA1 and, more commonly, BRCA2 mutations are associated with increased risk of male breast cancer (MBC). However, only a paucity of data exists on the pathology of breast cancers (BCs) in men with BRCA1/2 mutations. Using the largest available dataset, we determined whether MBCs arising in BRCA1/2 mutation carriers display specific pathologic features and whether these features differ from those of BRCA1/2 female BCs (FBCs). Methods We characterised the pathologic features of 419 BRCA1/2 MBCs and, using logistic regression analysis, contrasted those with data from 9675 BRCA1/2 FBCs and with population-based data from 6351 MBCs in the Surveillance, Epidemiology, and End Results (…