Search results for "cART"
showing 10 items of 2010 documents
Estudio presurométrico y biomecánico del pie en el pádel
2014
[EN] Padel is a very popular sport in countries like Spain, Argentina and Brazil, but there is a lack of scientific papers analyzing the harmfulness of their practice. Padel movements could potentially damage the foot and ankle joint. Therefore, the objective of this study was the characterization of the foot role during the execution of the most representative padel movements by techniques of pressurometry and video. The study was divided in two parts: pressurometric analysis of two movements (head-on displacement and split-step), and video recording of the foot during two games. The main conclusions of the study are the importance of forefoot zone in the padel movements, the importance of…
Effects of BIS076 in a model of osteoarthritis induced by anterior cruciate ligament transection in ovariectomised rats
2015
Background Osteoarthritis (OA) is the most frequent articular disease and a leading cause of disability. There is a need for effective treatments able to slow the progression of disease. Some of the available treatments are dietary supplements providing natural components. Recent studies have shown that estrogen deficiency contributes to the pathophysiological events of OA progression. Methods We have used the anterior cruciate ligament transection model of OA in ovariectomised rats to study the effects of BIS076, a new formulation of a natural porcine cartilage extract associated with hydroxyapatite (as a source of calcium) and vitamin D3. Cartilage degradation, proteoglycan depletion and …
Transplantation of Mesenchymal Stem Cells Exerts a Greater Long-Term Effect than Bone Marrow Mononuclear Cells in a Chronic Myocardial Infarction Mod…
2010
The aim of this study is to assess the long-term effect of mesenchymal stem cells (MSC) transplantation in a rat model of chronic myocardial infarction (MI) in comparison with the effect of bone marrow mononuclear cells (BM-MNC) transplant. Five weeks after induction of MI, rats were allocated to receive intramyocardial injection of 106 GFP-expressing cells (BM-MNC or MSC) or medium as control. Heart function (echocardiography and 18F-FDG-microPET) and histological studies were performed 3 months after transplantation and cell fate was analyzed along the experiment (1 and 2 weeks and 1 and 3 months). The main findings of this study were that both BM-derived populations, BM-MNC and MSC, ind…
Developmental expression of human cartilage matrix protein.
1994
Cartilage matrix protein (CMP) is a non-collagenous component of cartilage with a yet unknown function. In this study we used in situ hybridization to investigate the temporal and sptial distribution of CMP transcripts during human embryonic and early fetal development, and compared it to the pattern of expression observed for collagen types I, II, X, and decorin. The distribution of CMP and collagen type II transcripts followed a similar pattern in the embryonic bone anlage, the fetal growth plate, and the developing vertebral column. Expression was highest in the upper hypertrophic and lower proliferative zone, whereas calcified cartilage was negative throughout the different stages of bo…
Oxidized Albumin and Cartilage Acidic Protein-1 as Blood Biomarkers to Predict Ischemic Stroke Outcomes.
2021
Background: There is high demand for blood biomarkers that reflect the therapeutic response or predict the outcomes of patients with acute ischemic stroke (AIS); however, few biomarkers have been evidentially verified to date. This study evaluated two proteins, oxidized albumin (OxHSA) and cartilage acidic protein-1 (CRTAC1), as potential prognostic markers of AIS.Methods: The ratio of OxHSA to normal albumin (%OxHSA) and the level of CRTAC1 in the sera of 74 AIS patients were analyzed on admission (day 0), and at 1 and 7 days after admission. AIS patients were divided into two groups according to their modified Rankin Scale (mRS) at 3 months after discharge: the low-mRS (mRS < 2) gr…
THU0413 New Formulation with Potential for the Prevention and Treatment of Osteoporosis and Osteoarthritis
2013
Background Osteoarthritis (OA) is a multidimensional disease that affects all anatomical joint structures, particularly cartilage, synovium and subchondral bone. In turn, osteoporosis (OP) is a skeletal disorder characterized by a compromised bone strength which substantially increases the risk of fracture. Both are common disorders which affect quality of life in elderly. Despite this, there is not any drug at the moment for the simultaneous prevention and treatment of osteoporosis and osteoarthritis. Objectives The aim of this study was to investigate the effect of a new formulation in a combined rat model of OP and OA. The formulation (BIS076) contains Vitamin D3, Hydroxyapatite as a sou…
The history of meniscal-surgery
2000
In comparison with other operative procedures, the history of meniscal-surgery offers some particular differences. Over a long period of time injuries of the semilunar-cartilages of the knee-joint were not generally recognised. In the 18th century only was the clinical picture roughly outlined. There is evidence, that parts of the meniscus were removed much earlier than we have historic proof of. These meniscal fragments were generally mistaken for "loose bodies" in the joints, not knowing the exact etiology. Operative interference with joints was afflicted with a very high incidence of infections and thus complications. Due to this reliable standards of sterility were imperative to obtain …
Descartesin liikkeen filosofia : tutkielma Descartesin mekaniikasta ja siihen liittyvästä metafysiikasta
2011
Tämä tutkielma käsittelee Descartesin fysiikkaa ja etenkin kappaleiden liikettä sekä siihen liittyvää metafysiikkaa. Erityistä huomiota saavat Descartesin käsitykset matematiikasta, havainnosta ja yleisestä tieteenfilosofiasta sekä etenkin matematiikan ja todellisuuden suhteesta ja ne pyritään liittämään Descartesin kokonaiskuvaan ajasta, avaruudesta ja geometriasta.
Pseudo-relatives, gerunds and infinitives in Romance: (only) superficial resemblances and structural connections
2013
L'argomento di questa monografia è un confronto tra i costrutti predicativi di tipo frasale nelle diverse varietà romanze. Mentre le pseudorelative sono diffuse pressoché in tutta la Romània, con qualche variazione parametrica minore, i gerundi predicativi e gli infiniti preposizionali sono usati solo in alcune varietà. Negli studi linguistici sull'argomento è mancata finora l'ottica comparativa, sia tra varietà diverse, sia tra costrutti predicativi diversi. Il mio lavoro si prefissa lo scopo di colmare questa lacuna, senza ignorare però i costrutti percettivi composti da un infinito semplice, che da parte della letteratura sono stati paragonati alle strutture predicative delle pseudorelat…
Differentiaalimuodot ja niiden integrointi euklidisten avaruuksien alimonistoilla
2016
Differentiaalimuodot ovat oleellinen osa modernin matematiikan koneistoa. Niitä käytetään paitsi geometrian tutkimuksessa, myös teoreettisen fysiikan kentällä muun muassa elektrostatiikassa, mekaniikassa ja termodynamiikassa. Differentiaalimuodot elävät luonnollisesti sileillä monistoilla, jotka puolestaan esiintyvät kaikkialla, missä on tarve puhua siisteistä joukoista koordinaattien avulla. Tässä tutkielmassa tutustutaan differentiaalimuotojen perusteoriaan alkaen euklidisten avaruuksien alimonistoista. Tämän jälkeen määritellään monistojen tangentti- ja kotangenttiavaruudet, k-muotojen ulkoinen tulo, differentiaalimuotojen ulkoinen derivaatta sekä lopulta differentiaalimuodon integraali …