Search results for "cFos"

showing 1 items of 1 documents

Hippocampal dopamine receptors modulate cFos expression in the rat nucleus accumbens evoked by chemical stimulation of the ventral hippocampus

2005

Recently, we have shown that D1 and D2 receptors in the ventral hippocampus (VH) modulate both the locomotor activation and the increase in dopamine (DA) levels in the rat nucleus accumbens (NAc) induced by NMDA stimulation of the VH. In the present study we analyze the possible role of VH D1 and D2 receptors in the modulation of the cFos expression in NAc (core and shell subregions) and in dorsal striatum. This was assessed by immunohistochemical analysis of cFos expression in the rat brains after retro-dialysis application of NMDA (50mM, 10 min) into VH, in absence and in presence of either the D1/D5 receptor antagonist SCH 23390 (100 and 250 microM, 60 min) or the D2 receptor antagonist …

Malemedicine.medical_specialtyN-Methylaspartatenucleus accumbensMicrodialysisStriatumNucleus accumbensHippocampusNucleus AccumbensReceptors DopamineCellular and Molecular Neurosciencechemistry.chemical_compoundDopamineDopamine receptor D2Internal medicinemedicineExcitatory Amino Acid AgonistsAnimalsRats WistarPharmacologyRacloprideSCH-23390ChemistryGenes fosBenzazepinesImmunohistochemistryStimulation ChemicalRatsNeostriatumcFosEndocrinologyD2Gene Expression Regulationnervous systemD1NMDADopamine receptorRacloprideNMDA receptorDopamine Antagonistsdopamineventral hippocampusmedicine.drug
researchProduct