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showing 10 items of 2320 documents
Distribution, ecology and conservation survey on Trifolium michelianum Savi (Fabaceae) in Sicily (Italy)
2013
We report the identification of four residual stations for Trifolium michelianum Savi (Fabaceae) in Sicily, whereas the species was documented to be extinct at the Gorgo Cerro station (western Sicily), the only locality previously reported in the literature. In addition to an update on the distribution of the species, a survey on the new Sicilian populations led to their biological, ecological and phytosociological characterization, as well as to an assessment of the risk factors. The species, here relegated to the limit of its distribution area, occurs in particularly sensitive and vulnerable environments, such as the “Mediterranean temporary ponds”, considered “priority” by the Council Di…
The self-reported causes of sleepiness in shift-working tram and truck drivers
2021
Identifying the causes of sleepiness in various safety-critical work environments is neces-sary for implementing more efficient fatigue management strategies. In transportation, little is known about drivers' own perceptions of these causes. Therefore, we instructed shift-working tram (n = 23) and long-haul truck drivers (n = 52) to report at the end of their shifts what made them sleepy if they felt so. These self-reports, measured on-duty sleepiness, and sleep amounts were recorded on every shift over a period of 2-3 weeks per driver. The causes of sleepiness were queried with smartphone applications and sleep logs. Sleepiness was measured with the Karolinska Sleepiness Scale (KSS) and sl…
Accumulation of sleep loss among shift-working truck drivers.
2021
Sleep loss is known to contribute to road traffic accidents. Professional drivers are vulnerable to curtailment of sleep due to long driving bouts and shift work. To fill in the gap in the literature related to the buildup of sleep loss in irregular shift systems, we recorded the sleep and working hours of 47 shift-working long-haul truck drivers during a two-week period. Sleep (time in bed) was verified by actigraphy and sleep logs. Sleepiness was measured using the Karolinska Sleepiness Scale (KSS). Individual sleep need was based on self-assessments. We examined the accumulated sleep versus self-reported sleep need across the study period, using midnights as points of observation, and th…
Inhibitor-Induced Dimerization of an Essential Oxidoreductase from African Trypanosomes
2018
Trypanosomal and leishmanial infections claim tens of thousands of lives each year. The metabolism of these unicellular eukaryotic parasites differs from the human host and their enzymes thus constitute promising drug targets. Tryparedoxin (Tpx) from Trypanosoma brucei is the essential oxidoreductase in the parasite's hydroperoxide-clearance cascade. In vitro and in vivo functional assays show that a small, selective inhibitor efficiently inhibits Tpx. With X-ray crystallography, SAXS, analytical SEC, SEC-MALS, MD simulations, ITC, and NMR spectroscopy, we show how covalent binding of this monofunctional inhibitor leads to Tpx dimerization. Intra- and intermolecular inhibitor-inhibitor, pro…
On the influence of curvature and torsion on turbulence in helically coiled pipes
2014
Turbulent flow and heat transfer in helically coiled pipes at Retau=400 was investigated by DNS using finite volume grids with up to 2.36×10E7 nodes. Two curvatures (0.1 and 0.3) and two torsions (0 and 0.3) were considered. The flow was fully developed hydrodynamically and thermally. The central discretization scheme was adopted for diffusion and advection terms, and the second order backward Euler scheme for time advancement. The grid spacing in wall units was ~3 radially, 7.5 circumferentially and 20 axially. The time step was equal to one viscous wall unit and simulations were typically protracted for 8000 time steps, the last 4000 of which were used to compute statistics. The results s…
Análisis del comportamiento de la demanda de turismo rural desde la experiencia de la comarca El Alto Palancia
2004
This study is intended to delve into the tastes and preferences of tourists visiting rural areas in Spain as an alternative to the traditional sun and beach holiday that dominates Spanish tourism. This paper is focused on the demand side of rural tourism; more specifically the extent to which tourists visiting a Spanish rural area. El Alto Palancia region, exhibit different behaviours depending on age, gender, incomes and educational background. The homogeneity of behaviour across several categories of tourists was tested in two sets of variables. First, «interest in certain resources associated with rural tourism», focused on natural and architectural resources that sustains the tourist's …
Reaching toward individualization in planning for children with special needs
2009
Integrating young children with special needs into programs for typically developing children is a current trend. Yet, integration may threaten a teacher's ability to meet the needs of an individual child. The aim of this study was to gain an understanding of the teachers’ orientation in early intervention/early childhood special education. Data from thirteen early childhood generic educators/early childhood special educators were collected to provide a qualitative description of their assessment and planning practices. Findings indicated that generic early childhood/early childhood special educators’ assessment, planning, and programming for meeting the needs of individual children were no…