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Il lavoro nel turismo
2019
Il contributo offre una breve disamina delle principali caratteristiche del mercato del lavoro nel settore del turismo. A partire dall’elemento della stagionalità, che si traduce in esigenze di flessibilità e dinamicità del mercato, si individuano le tipologie contrattuali cui prevalentemente si suole far ricorso. Con l’ausilio di risultanze empiriche, desumibili dalle principali banche dati a disposizione, viene restituito un quadro di modelli organizzativi prevalenti (il contratto di lavoro a tempo determinato, il part-time, il contratto di apprendistato, il lavoro intermittente); in cui, dunque, i contratti diversi dai “classici” modelli a tempo indeterminato e/o tempo pieno costituiscon…
Elements of Sustainability for Public Sector Software : Mosaic Enterprise Architecture, Macroservices, and Low-Code
2021
Public sector is a large consumer for software. In countries such as Finland, many of the systems are made to order by consultancy companies that participate in public tenders. These tenders initiated by the state, cities, and other public sector organizations. Furthermore, as public sector tasks are often decomposed to various actors, each and every one of them makes their purchase based on their own needs. In this paper, we argue that to maintain software sustainability in this context, there is a need for three key elements. Firstly, there is a need for an enterprise architecture where independent services from various vendors are can be easily deployed and integrated. Secondly, these se…
VARIABILITY OF REMOTE SENSING SPECTRAL INDICES IN BOREAL LAKE BASINS
2018
Remotely sensed hyperspectral data has widely been used to determine water quality parameters in oceanic waters. However in freshwater basins the dependence between the hyperspectral data and the parameters is more complicated. In this work some ideas are presented concerning the study of this dependence. The data used in this study were collected from the lake Hiidenvesi in southern Finland. The hyperspectral data consists of reflectances in 36 bands in the wavelength area 508…878 nm and the separately measured water quality parameters are turbidity, blue-green algae, chlorophyll, pH and dissolved oxygen. Hyperspectral data was used as bare band reflectances, but also in the …
Gray Matter Changes in the Orbitofrontal-Paralimbic Cortex in Male Youths With Non-comorbid Conduct Disorder
2020
Conduct disorder is one of the most common developmental psychiatric disorders which is characterized by persistent aggressive and antisocial behaviors during childhood or adolescence. Previous neuroimaging studies have investigated the neural correlates underlying CD and demonstrated several constructive findings. However, Individuals with CD are at high risk for comorbidities, which might give rise to the inconsistencies of existed findings. It remains unclear which neuroanatomical abnormalities are specifically related to CD without comorbidities. Using structural magnetic resonance imaging (sMRI) data of 69 CD and 69 typically developing (TD) male youths (aged 14-17 years), the present …
Ethnic diversity in the construction of life stories in Latvia
2017
Ethnic diversity in the construction of life stories in Latvia Latvian society is ethnically diverse and has the largest proportion of ethnic minorities of the three Baltic States. The article draws upon life-story research with respondents from Russian and Romany communities in Latvia. These communities have different social, historical and cultural experiences, thereby allowing them to be contrasted and compared. Ethnic diversity can be considered one of the benefits of Latvia’s cultural identity because it provides the opportunity not only to become acquainted with the characteristics and uniqueness of each culture but also to establish which traits unite these cultures, thereby creating…
Multiplicity results for asymmetric boundary value problems with indefinite weights
2004
We prove existence and multiplicity of solutions, with prescribed nodal properties, to a boundary value problem of the formu″+f(t,u)=0,u(0)=u(T)=0. The nonlinearity is supposed to satisfy asymmetric, asymptotically linear assumptions involving indefinite weights. We first study some auxiliary half-linear, two-weighted problems for which an eigenvalue theory holds. Multiplicity is ensured by assumptions expressed in terms of weighted eigenvalues. The proof is developed in the framework of topological methods and is based on some relations between rotation numbers and weighted eigenvalues.
Increased autophagy and apoptosis contribute to muscle atrophy in a myotonic dystrophy type 1 Drosophila model
2015
ABSTRACT Muscle mass wasting is one of the most debilitating symptoms of myotonic dystrophy type 1 (DM1) disease, ultimately leading to immobility, respiratory defects, dysarthria, dysphagia and death in advanced stages of the disease. In order to study the molecular mechanisms leading to the degenerative loss of adult muscle tissue in DM1, we generated an inducible Drosophila model of expanded CTG trinucleotide repeat toxicity that resembles an adult-onset form of the disease. Heat-shock induced expression of 480 CUG repeats in adult flies resulted in a reduction in the area of the indirect flight muscles. In these model flies, reduction of muscle area was concomitant with increased apopto…
The distributions of protein coding genes within chromatin domains in relation to human disease.
2019
Abstract Background Our understanding of the nuclear chromatin structure has increased hugely during the last years mainly as a consequence of the advances in chromatin conformation capture methods like Hi-C. The unprecedented resolution of genome-wide interaction maps shows functional consequences that extend the initial thought of an efficient DNA packaging mechanism: gene regulation, DNA repair, chromosomal translocations and evolutionary rearrangements seem to be only the peak of the iceberg. One key concept emerging from this research is the topologically associating domains (TADs) whose functional role in gene regulation and their association with disease is not fully untangled. Resul…
"If I don’t enjoy it, how are my kids going to enjoy it?" : case study in English grammar teaching
2015
The question over how grammar should be taught has been discussed amongst s everal linguistics scholars. Different grammar teaching methods present different focus on the target language, grammar and learner’s role. All of the methods have their strengths and weaknesses and in order to know which method to pick, one must know all the strengths and weaknesses of these methods. In this case study, a teacher from Central Finland was interviewed on her grammar teaching methods and the reasons behind these methods for fifth-graders. Factors influencing her selection of methods were the grammatical topic to be taught, learners’ different learning styles, relevance of the topic and the most natura…
RNA-Binding Proteins as Epigenetic Regulators of Brain Functions and Their Involvement in Neurodegeneration.
2022
A central aspect of nervous system development and function is the post-transcriptional regulation of mRNA fate, which implies time- and site-dependent translation, in response to cues originating from cell-to-cell crosstalk. Such events are fundamental for the establishment of brain cell asymmetry, as well as of long-lasting modifications of synapses (long-term potentiation: LTP), responsible for learning, memory, and higher cognitive functions. Post-transcriptional regulation is in turn dependent on RNA-binding proteins that, by recognizing and binding brief RNA sequences, base modifications, or secondary/tertiary structures, are able to control maturation, localization, stability, and tr…