Search results for "camp"
showing 10 items of 1995 documents
Involvement of cyclin-dependent kinase-5 in the kainic acid-mediated degeneration of glutamatergic synapses in the rat hippocampus
2011
Increased levels of glutamate causing excitotoxic damage accompany neurological disorders such as ischemia/stroke, epilepsy and some neurodegenerative diseases. Cyclin-dependent kinase-5 (Cdk5) is important for synaptic plasticity and is deregulated in neurodegenerative diseases. However, the mechanisms by which kainic acid (KA)-induced excitotoxic damage involves Cdk5 in neuronal injury are not fully understood. In this work, we have thus studied involvement of Cdk5 in the KA-mediated degeneration of glutamatergic synapses in the rat hippocampus. KA induced degeneration of mossy fiber synapses and decreased glutamate receptor (GluR)6/7 and post-synaptic density protein 95 (PSD95) levels in…
¿Una feria de cambios a la valenciana? Debate financiero y energía emprendedora en el siglo XVII
2020
In 1619 Philip IV sent to print a Real Pragmatic [Royal Pragmatic legislation] that would regulate changes between Valencia and Medina del Campo being introduced by Valencian merchant families to enable them to receive interest on their loans without being accused of usury. Only three years later, in 1622, the Republic of Genoa inaugurated the exchange fairs of Novi Ligure, with which the Genoese consolidated their international position in the international credit market. These apparently independent circumstances constitute an important episode for international financial knowledge and the transformation of the Mediterranean credit market during the seventeenth century. Studying financial…
Investigating Mobility Gaps in University Campuses
2018
The objective of the present research is to carry out a gap analysis between current mobility situations and the needs, future plans and priorities regarding a number of thematic areas on the issue of mobility in university campuses. For this purpose, an interview was conducted involving 36 experts from seven Southern European Universities. More specifically, experts from each university were asked to analyse and rate both the current and the desired situation in the campus under their responsibility with focus on the following thematic areas: parking management, soft modes infrastructure, public transport, car related issues, road infrastructure, environment and energy, mobility management…
Peace Mediations: Recourse to the Arbitration in the kingdom of Valencia (XIV-XV Centuries)
2017
Arbitration, as a means of conciliation, had an extraordinary diffusion in the Medieval West. It had the advantage of being more quick and, generally, less expensive that the causes resolved by the ordinary courts. Moreover, it tried to reconcile the interests of the warring parties. This paper seeks to define the main features of the arbitration in the kingdom of Valencia during the Middle Ages focusing the observation on the small rural community of Vilafranca.
Sociología, Derecho y desigualdades sociales. Una propuesta de docencia universitaria crítica
2019
Fil: Di Nella, Dino. Universidad Nacional de Río Negro. Río Negro, Argentina. Fil: Almeda, Elisabet. Universidad de Barcelona. Catalunya, España. Fil: Camps Calvet, Clara. Universidad de Barcelona. Catalunya, España. Fil: Giordana, Patricia. Universidad Nacional de Río Negro. Río Negro, Argentina. Fil: Loggiacco, Camila. Universidad Nacional de Río Negro. Río Negro, Argentina. Fil: D'Alfonso, Luis. Universidad Nacional de Río Negro. Río Negro, Argentina. Critic education in human rights and social inequalities must be able to capture holistic and mutidmiensional sphere that Human Rights requires. This study introduces the basis in which critic university teaching proposal is carectarized by…
Constraints on off-shell Higgs boson production and the Higgs boson total width in ZZ → 4ℓ and ZZ → 2ℓ2ν final states with the ATLAS detector
2018
A measurement of off-shell Higgs boson production in the and decay channels, where ℓ stands for either an electron or a muon, is performed using data from proton–proton collisions at a centre-of-mass energy of TeV. The data were collected by the ATLAS experiment in 2015 and 2016 at the Large Hadron Collider, and they correspond to an integrated luminosity of . An observed (expected) upper limit on the off-shell Higgs signal strength, defined as the event yield normalised to the Standard Model prediction, of 3.8 (3.4) is obtained at 95% confidence level (CL). Assuming the ratio of the Higgs boson couplings to the Standard Model predictions is independent of the momentum transfer of the Higgs…
La dimensión narrativa en el discurso político argentino. La campaña del "Frente de Todos" en redes sociales
2020
Jyväskylän yliopiston kampus, Seminaarinmäki : Jyväskylä, Alvar Aalto 1951-1971 & Arto Sipinen 1970-1974
2017
Essential omega-3 fatty acids tune microglial phagocytosis of synaptic elements in the developing brain
2019
SUMMARYOmega-3 fatty acids (n-3 polyunsaturated fatty acids; n-3 PUFAs) are essential for the functional maturation of the brain. Westernization of dietary habits in both developed and developing countries is accompanied by a progressive reduction in dietary intake of n-3 PUFAs. Low maternal intake of n-3 PUFAs has been linked to neurodevelopmental diseases in epidemiological studies, but the mechanisms by which a n-3 PUFA dietary imbalance affects CNS development are poorly understood. Active microglial engulfment of synaptic elements is an important process for normal brain development and altered synapse refinement is a hallmark of several neurodevelopmental disorders. Here, we identify …
Salmeterol Xinafoate (SX) loaded into mucoadhesive solid lipid microparticles for COPD treatment
2019
Chronic obstructive pulmonary disease (COPD) is one of the main health problems worldwide. It is characterised by chronic inflammation in the lungs that leads to progressive, chronic, largely irreversible airflow obstruction. The use of long-acting β agonists remain today the frontline treatment for COPD with the aim of minimizing side effects and enhancing therapeutic usefulness. To this purpose, in this paper, mucoadhesive solid lipid microparticles (SLMs) containing a long-acting β-2 agonist, Salmeterol Xinafoate (SX) were prepared, characterised (size, z-potential, aerodynamic diameter, turbidimetric evaluations, drug loading and entrapping efficiency) and tested in a model of bronchial…