Search results for "campus"

Divergent impact of the polysialyltransferases ST8SiaII and ST8SiaIV on polysialic acid expression in immature neurons and interneurons of the adult …

2010

Polysialic acid (PSA) is a negatively charged carbohydrate polymer, which confers antiadhesive properties to the neural cell adhesion molecule NCAM and facilitates cellular plasticity during brain development. In mice, PSA expression decreases drastically during the first postnatal weeks and it gets confined to immature neurons and regions displaying structural plasticity during adulthood. In the brain, PSA is exclusively synthesized by the two polysialyltransferases ST8SiaII and ST8SiaIV. To study their individual contribution to polysialylation in the adult, we analyzed PSA expression in mice deficient for either polysialyltransferase. Focusing on the cerebral cortex, our results indicate…

Human adult periodontal ligament-derived cells integrate and differentiate after implantation into the adult mammalian brain.

2013

Previous studies suggest that neural crest (NC)-derived stem cells may reside in NC derivatives including the human periodontal ligament (hPDL). The isolation and manipulation of autologous NC-derived cells could be an accessible source of adult neural stem cells for their use in cell replacement and gene transfer to the diseased central nervous system. In this study, we examined the expression of NC markers and neural differentiation potential of hPDL-derived cells both in vitro and in vivo. In vitro we found that hPDL-derived cells expressed stem cell markers (Oct3/4, Nestin, Sox2, and Musashi-1) and a subset of NC cell markers (Slug, p75(NTR), Twist, and Sox9). hPDL-derived cells differe…

Alma Mater: 2012/ Ziema

2012

Karyotypes in two species of the genusHippocampus (Pisces: Syngnatiformes)

1988

Diploid modal numbers of chromosomes 2n=48 forHippocampus ramulosus and 2n=44 forH. hippocampus, collected in the Gulf of Palermo in May 1985, are established. No sex-linked heteromorphic pairs are observed in the two species analyzed. The karyotype ofH. hippocampus seems to be a derived condition.

Apical dendritic spines and axonic terminals in the bipyramidal neurons of the dorsomedial cortex of lizards (Lacerta).

1984

Gold-toned bipyramidal neurons of the dorsomedial cortex of Lacerta have been studied using light and electron microscopy. The spines have been classified as stubby, mushroom-shaped or thin. Thin and mushroom-shaped spines are only found on proximal and intermediate dendritic segments, whereas stubby spines are found on distal dendritic segments. A Timm's method modification for electron microscopy (sulphide-osmium procedure) has been used. Timm-positive axonal endings usually synapse on thin and mushroom-shaped spines, whereas Timm-negative axonal endings usually synapse on stubby spines. Timm-positive afferents and their post-synaptic spines on bipyramidal neurons of Lacerta's dorsomedial…

Antagonism between brain regions relevant for cognitive control and emotional memory facilitates the generation of humorous ideas

2021

Abstract The ability to generate humor gives rise to positive emotions and thus facilitate the successful resolution of adversity. Although there is consensus that inhibitory processes might be related to broaden the way of thinking, the neural underpinnings of these mechanisms are largely unknown. Here, we use functional Magnetic Resonance Imaging, a humorous alternative uses task and a stroop task, to investigate the brain mechanisms underlying the emergence of humorous ideas in 24 subjects. Neuroimaging results indicate that greater cognitive control abilities are associated with increased activation in the amygdala, the hippocampus and the superior and medial frontal gyrus during the ge…

Structure and performance assessment in traditional face-to-face and blended learning statistics courses

2014

Abstract In recent years the number of higher education institutions offering blended learning courses has increased notably. Blended learning is understood as the combination of traditional face-to-face teaching with online and distance learning. During the 2012- 13 academic year, for the first time, the Information and Documentation degree course at the University of Barcelona included a blended learning format in its course in statistics. The blended learning course combined biweekly face-to-face classes and online work between sessions. This study describes the organization of the blended course in comparison with the traditional face-to- face course and presents preliminary data on stu…

Case study: developing campus spaces through co-creation

2016

ABSTRACTHigher education institutions are designed to support their core processes – learning, teaching, research, and societal impact. In order for university facilities to support these activities, it is crucial to determine together with the users what these activities are and how they are supposed to be developed in the future. This article examines the relationship between user needs and the service level in construction projects through a case study where a university cafeteria was renovated using a participatory design (PD) method called charrette. The aim of this case study was to study the effects of collaborative ways of working when applied to a space retrofit project, and how th…

IC‐P‐122: Association of hippocampus head diffusivity and episodic memory performance in early Alzheimer's disease

2009

Dopaminergic control of feline hippocampal epilepsy: A nigrophippocampal pathway

1991

Abstract Substantia nigra is a mesencephalic structure inserted along several circuits which appear to play a key role in epilepsy. In previous researches we postulated that substantia nigra pars compacta (SNpc) may be the site of a precise control of hippocampal epilepsy while substantia nigra pars reticulata (SNpr) may exert a modulation of both neocortical epilepsy and spreading of hyperactivity toward a motor target. In order to better understand mechanisms subserving nigral action in feline hippocampal epilepsy we electrically stimulated SNpc (dopaminergic), before and after sulpiride (dopamine receptor-antagonist) intravenous injection. Furthermore we compared hippocampal epileptiform…