Search results for "carboxylic acid"

showing 10 items of 460 documents

CCDC 800674: Experimental Crystal Structure Determination

2011

Related Article: D.Siebler, C.Forster, T.Gasi, K.Heinze|2011|Organometallics|30|313|doi:10.1021/om1010808

1-carboxylic acid methyl ester-1-(t-butoxycarbonylamino)biferrocenium tri-iodideSpace GroupCrystallographyCrystal SystemCrystal StructureCell ParametersExperimental 3D Coordinates
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CCDC 973532: Experimental Crystal Structure Determination

2014

Related Article: Ludovico G. Tulli, Negar Moridi, Wenjie Wang, Kaisa Helttunen, Markus Neuburger, David Vaknin, Wolfgang Meier, Patrick Shahgaldian|2014|Chem.Commun.|50|3938|doi:10.1039/C4CC00928B

25262728-tetrakis(Dodecyloxy)pentacyclo[19.3.1.137.1913.11519]octacosa-1(25)3(28)469(27)101215(26)16182123-dodecaene-5111723-tetracarboxylic acid pyridine solvateSpace GroupCrystallographyCrystal SystemCrystal StructureCell ParametersExperimental 3D Coordinates
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CCDC 886816: Experimental Crystal Structure Determination

2013

Related Article: I.Goba,B.Turovska,S.Belyakov,E.Liepinsh|2013|Khim.Get.Soedin.,SSSR||778|

3-Acetyl-5-cyano-26-dimethyl-14-dihydropyridine-4-carboxylic acidSpace GroupCrystallographyCrystal SystemCrystal StructureCell ParametersExperimental 3D Coordinates
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Synthesis of New 2-{[(Phenoxy or Phenyl)acetyl]amino}benzoic Acid Derivatives as 3α-Hydroxysteroid Dehydrogenase Inhibitors and Potential Antiinflamm…

1995

A number of 2-([(phenoxy or phenyl)acetyl]amino)benzoic acid derivatives were prepared in about 50% yield from (phenoxy or phenyl)acetyl chloride and anthranilic acid derivatives. All the compounds were tested as in vitro inhibitors of 3 alpha-hydroxysteroid dehydrogenase, since enzyme inhibition predicts potential antiinflammatory activity in vivo. The most active compounds 3 l, m, s are about 3.5 times more active than acetylsalicylic acid (ASA). Activity is influenced by electronic as well as steric effects.

3-Hydroxysteroid Dehydrogenasesmedicine.drug_classStereochemistryCarboxylic acidPharmaceutical ScienceCarboxamideEtherMicrobial Sensitivity TestsIn Vitro TechniquesChemical synthesischemistry.chemical_compoundAnti-Infective AgentsAcetyl chlorideYeastsDrug DiscoverymedicineAnthranilic acidAnimalsAminobenzoatesEnzyme InhibitorsBenzoic acidchemistry.chemical_classificationBacteriabiologyAnti-Inflammatory Agents Non-SteroidalAnti-Bacterial AgentsRatschemistryEnzyme inhibitorbiology.proteinArchiv der Pharmazie
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CCDC 2144108: Experimental Crystal Structure Determination

2022

Related Article: Natalina Makieieva, Teobald Kupka, Grzegorz Spaleniak, Oimahmad Rahmonov, Agata Marek, Alfred Błażytko, Leszek Stobiński, Nataliya Stadnytska, Danuta Pentak, Aneta Buczek, Małgorzata A. Broda, Piotr Kuś, Joachim Kusz, Maria Książek|2022|Struct.Chem.|33|2133|doi:10.1007/s11224-022-02026-7

4-oxo-4H-pyran-26-dicarboxylic acid methanol solvateSpace GroupCrystallographyCrystal SystemCrystal StructureCell ParametersExperimental 3D Coordinates
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CCDC 747264: Experimental Crystal Structure Determination

2009

Related Article: F.Caruso, M.V.Raimondi, G.Daidone, C.Pettinari, M.Rossi|2009|Acta Crystallogr.,Sect.E:Struct.Rep.Online|65|o2173|doi:10.1107/S1600536809032188

5-Amino-1-phenyl-3-(trifluoromethyl)-1H-pyrazole-4-carboxylic acidSpace GroupCrystallographyCrystal SystemCrystal StructureCell ParametersExperimental 3D Coordinates
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CCDC 633848: Experimental Crystal Structure Determination

2007

Related Article: M.Albrecht, Triyanti, S.Schiffers, O.Osetska, G.Raabe, T.Wieland, L.Russo, K.Rissanen|2007|Eur.J.Org.Chem.|2007|2850|doi:10.1002/ejoc.200700130

8-(3-n-Butylureido)-4-isobutoxyquinoline-2-carboxylic acid phenyl amide acetonitrile solvateSpace GroupCrystallographyCrystal SystemCrystal StructureCell ParametersExperimental 3D Coordinates
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CCDC 1452354: Experimental Crystal Structure Determination

2016

Related Article: Negera Abdissa, Fangfang Pan, Amra Gruhonjic, Jürgen Gräfenstein, Paul A. Fitzpatrick, Göran Landberg, Kari Rissanen, Abiy Yenesew, Máté Erdélyi|2016|J.Nat.Prod.|79|2181|doi:10.1021/acs.jnatprod.6b00178

9-hydroxy-212-dimethoxy-35a-dimethyl-233a455a12c12d-octahydro-16-dioxabenzo[l]acephenanthrylene-10-carboxylic acidSpace GroupCrystallographyCrystal SystemCrystal StructureCell ParametersExperimental 3D Coordinates
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Pharmacological activation of CB2 receptors counteracts the deleterious effect of ethanol on cell proliferation in the main neurogenic zones of the a…

2015

Chronic alcohol exposure reduces endocannabinoid activity and disrupts adult neurogenesis in rodents, which results in structural and functional alterations. Cannabinoid receptor agonists promote adult neural progenitor cell (NPC) proliferation. We evaluated the protective effects of the selective CB1 receptor agonist ACEA, the selective CB2 receptor agonist JWH133 and the fatty-acid amide-hydrolase (FAAH) inhibitor URB597, which enhances endocannabinoid receptor activity, on NPC proliferation in rats with forced consumption of ethanol (10%) or sucrose liquid diets for 2 weeks. We performed immunohistochemical and stereological analyses of cells expressing the mitotic phosphorylation of his…

:Phenomena and Processes::Physiological Phenomena::Physiological Processes::Growth and Development::Morphogenesis::Embryonic and Fetal Development::Organogenesis::Neurogenesis [Medical Subject Headings]CB1 receptorTubulina (proteína)Cannabinoid receptorCarbamatosEtanol:Chemicals and Drugs::Amino Acids Peptides and Proteins::Proteins::Nuclear Proteins::Histones [Medical Subject Headings]Ventrículos lateralesSacarosaNeuronasSubgranular zone0302 clinical medicine:Chemicals and Drugs::Amino Acids Peptides and Proteins::Proteins::Membrane Proteins::Receptors Cell Surface::Receptors G-Protein-Coupled::Receptors Cannabinoid::Receptor Cannabinoid CB1 [Medical Subject Headings]Histonas:Chemicals and Drugs::Organic Chemicals::Carboxylic Acids::Acids Acyclic::Carbamates [Medical Subject Headings]Receptor cannabinoide CB1Cannabinoid receptor type 2:Organisms::Eukaryota::Animals [Medical Subject Headings]:Phenomena and Processes::Metabolic Phenomena::Metabolism::Phosphorylation [Medical Subject Headings]:Anatomy::Cells::Stem Cells::Neural Stem Cells [Medical Subject Headings]:Anatomy::Nervous System::Neurons [Medical Subject Headings]health care economics and organizations:Anatomy::Nervous System::Central Nervous System::Brain::Cerebral Ventricles::Lateral Ventricles [Medical Subject Headings]Original Research:Chemicals and Drugs::Nucleic Acids Nucleotides and Nucleosides::Nucleosides::Deoxyribonucleosides::Deoxyuridine::Bromodeoxyuridine [Medical Subject Headings]0303 health sciencesAlcoholismoalcoholConsumo de alcoholNeurogenesis:Phenomena and Processes::Genetic Phenomena::Phenotype::Genetic Markers [Medical Subject Headings]:Chemicals and Drugs::Chemical Actions and Uses::Pharmacologic Actions::Molecular Mechanisms of Pharmacological Action::Neurotransmitter Agents::Cannabinoid Receptor Modulators::Cannabinoid Receptor Agonists [Medical Subject Headings]Benzamidas:Chemicals and Drugs::Amino Acids Peptides and Proteins::Proteins::Membrane Proteins::Receptors Cell Surface::Receptors G-Protein-Coupled::Receptors Cannabinoid::Receptor Cannabinoid CB2 [Medical Subject Headings]Endocannabinoid system3. Good healthbromodesoxiuridinaneurogenesisEndocannabinoidesmedicine.anatomical_structure:Chemicals and Drugs::Enzymes and Coenzymes::Enzymes::Hydrolases [Medical Subject Headings]ACEADietaAlcoholFosforilaciónAgonistmedicine.medical_specialtyHidrolasasmedicine.drug_classNeurogenesiseducation:Psychiatry and Psychology::Mental Disorders::Substance-Related Disorders::Alcohol-Related Disorders::Alcoholism [Medical Subject Headings]Subventricular zoneBiology:Phenomena and Processes::Physiological Phenomena::Nutritional Physiological Phenomena::Diet [Medical Subject Headings]:Anatomy::Nervous System::Central Nervous System::Brain::Prosencephalon::Telencephalon::Cerebrum::Cerebral Cortex::Hippocampus::Dentate Gyrus [Medical Subject Headings]lcsh:RC321-57103 medical and health sciencesCellular and Molecular NeuroscienceRatasInternal medicine:Chemicals and Drugs::Amino Acids Peptides and Proteins::Proteins::Nerve Tissue Proteins::Tubulin [Medical Subject Headings]JWH133medicineGiro dentadolcsh:Neurosciences. Biological psychiatry. Neuropsychiatry030304 developmental biologyCélulas madre nerviosas:Chemicals and Drugs::Chemical Actions and Uses::Pharmacologic Actions::Molecular Mechanisms of Pharmacological Action::Neurotransmitter Agents::Endocannabinoids [Medical Subject Headings]Dentate gyrusmarcadores genéticosCB2 receptor:Chemicals and Drugs::Carbohydrates::Polysaccharides::Oligosaccharides::Disaccharides::Sucrose [Medical Subject Headings]:Anatomy::Nervous System::Central Nervous System::Brain::Prosencephalon::Diencephalon::Hypothalamus [Medical Subject Headings]:Chemicals and Drugs::Organic Chemicals::Alcohols::Ethanol [Medical Subject Headings]Endocrinology:Organisms::Eukaryota::Animals::Chordata::Vertebrates::Mammals::Rodentia::Muridae::Murinae::Rats [Medical Subject Headings]nervous system:Psychiatry and Psychology::Behavior and Behavior Mechanisms::Behavior::Drinking Behavior::Alcohol Drinking [Medical Subject Headings]:Chemicals and Drugs::Organic Chemicals::Amides::Benzamides [Medical Subject Headings]030217 neurology & neurosurgeryHipotálamoNeuroscience
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1-Aminocyclopropane-1-Carboxylic Acid, its Malonyl Conjugate and 1-Aminocyclopropane-1-Carboxylate Synthase Activity in Needles of Damaged and Undama…

1994

Summary Levels of free 1-aminocyclopropane-1-carboxylic acid (ACC), its malonyl conjugate (MACC) and ACC-synthase activity were significantly higher in the needles of damaged Norway spruce trees ( Picea abies (L.) Karst ) compared with those in undamaged trees during both the diurnal and seasonal courses. The concentrations of ACC and MACC, and ACC-synthase activity fluctuated much more intensively in the needles of damaged trees both in the diurnal and the seasonal courses than in those of undamaged ones, which implies that damaged trees respond more sensitively to the environmental conditions. ACC concentrations were the highest in summer and lowest in fall, while MACC concentrations seem…

ACC SYNTHASEDevelopmental stagebiologyPhysiologyChemistryBaden wurttembergPicea abiesPlant Sciencebiology.organism_classificationbehavioral disciplines and activitiesstomatognathic diseaseschemistry.chemical_compoundnervous systemBotanybiology.protein1-Aminocyclopropane-1-carboxylic acidCarbon-Sulfur Lyases1-aminocyclopropane-1-carboxylate synthasehuman activitiesAgronomy and Crop Sciencepsychological phenomena and processesConjugateJournal of Plant Physiology
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