Search results for "cb"
showing 10 items of 647 documents
Evolution of a Non-Hermitian Quantum Single-Molecule Junction at Constant Temperature
2021
This work concerns the theoretical description of the quantum dynamics of molecular junctions with thermal fluctuations and probability losses. To this end, we propose a theory for describing non-Hermitian quantum systems embedded in constant-temperature environments. Along the lines discussed in [A. Sergi et al., Symmetry 10 518 (2018)], we adopt the operator-valued Wigner formulation of quantum mechanics (wherein the density matrix depends on the points of the Wigner phase space associated to the system) and derive a non-linear equation of motion. Moreover, we introduce a model for a non-Hermitian quantum single-molecule junction (nHQSMJ). In this model the leads are mapped to a tunneling…
Discretionary fiscal policy over the cycle: new evidence based on the ESCB Disaggregated Approach
2009
This paper explores how discretionary fiscal policies on the revenue side of the government budget have reacted to economic fluctuations in European Union countries. For this purpose, it uses data on legislated revenue changes and structural indicators provided twice per year by National Central Banks of European Union countries in the ESCB framework for analysing fiscal policy. The analysis is based on the estimation of fiscal policy rules linking these measures of legislated fiscal policy changes to the output gap and other control variables. Then, baseline results are compared with regression estimates where variations of cyclically-adjusted indicators are used as proxy for discretionary…
Rash and multiorgan dysfunction following lamotrigine: could genetic be involved?
2015
We report the case of a 38-year-old woman treated with lamotrigine who experienced multi-organ dysfunction. The patient received the drug at the dose of 100 mg per day. One week later, the treatment was suspended because of an extensive body rash. Twenty-four hours later, the patient appeared drowsy and stuporous and was hospitalized. On the fifth day, the patient was admitted with a clinical picture of acute multi-organ failure in our Institute, where, she, despite the support of vital functions with vasoactive drugs, continuous hemofiltration and ventilation with oxygen, died. Serum lamotrigine concentration was measured 110 h after its last dose and the drug resulted to be still present …
Rol del complejo RUNX1-CBF-β/HIPK2/p300/p53 en la evolución leucémica de las neoplasias mieloproliferativas crónicas
2019
Las neoplasias mieloproliferativas crónicas (NMPs) son procesos cancerígenos en los que se produce una expansión clonal de una o varias poblaciones de progenitores hematopoyéticos de estirpe mieloide. En las fases iniciales de la enfermedad, éstos presentan una adecuada diferenciación celular, lo que conlleva una descompensación final de los diferentes tipos celulares en médula ósea y sangre periférica y la consiguiente aparición de una serie de síntomas asociados que pueden llegar a producir importantes citopenias o complicaciones vasculares. A pesar de que las NMPs pueden mantenerse relativamente controladas en su fase crónica mediante un tratamiento adecuado, éstas patologías tienen una …
Komercbanku resursu avotu analīze eirozonā
2016
Bakalaura darba tēma ir “Komercbanku resursu avotu analīze eirozonā”. Darba mērķis ir balstoties uz teorētiskām nostādnēm par komercbanku resursu avotu nozīmi banku stabilitātē, veikt eirozonas komercbanku resursu avotu un procenta likmju analīzi, izdarīt secinājumus un sniegt priekšlikumus resursu avotu struktūras sabalansēšanai bankas darbības stabilitātes uzlabošanas mērķiem. Darbs sastāv no 3 nodaļām un 6 apakšnodaļām. Pirmajā nodaļā apskatīti, banku resursu avoti un to saistība ar finanšu riskiem. Otrajā nodaļā analizēts, eirozonas komercbanku resursu avotu īpatsvars un procentu likmju izmaiņas. Trešajā nodaļā analizētas Latvijas komercbanku resursu avotu īpatsvara izmaiņas. Darba apjo…
Ekonomisko svārstību ietekme uz cilvēkkapitāla attīstību
2017
Šajā darbā autors ir vēlējies uzsvērt pastāvošo problēmu par to, ka vislielākie cietēji recesiju laikā ir iedzīvotāji jeb cilvēkkapitāls, kurš bieži vien tiek atstāts novārtā un netiek pamanīts. Darba būtība bija parādīt to, ka pastāv negatīva saikne uz cilvēkkapitālu ekonomikas lejupslīdes laikā. Pētījuma mērķis bija noskaidrot to, kuri ir tie faktori, kas ietkmē ekonomikas pārkaršanu jeb recesiju. Kā arī saprast to kā šie faktori ietekmē cilvēkkapitālu un tā attīstību. Savukārt, uzdevumi bija saistīti ar to, lai tiktu noskaidrots konkrētās nozares un tās instrumentu ietekme uz ekonomiskajaiem procesiem un to ietekmi uz cilvēkkapitālu. Tika pētītas gan CB, gan bankas kā arī valdības un to …
The oxidizing agent tertiary butyl hydroperoxide induces disturbances in spindle organization, c-meiosis, and aneuploidy in mouse oocytes
1996
It has been recently proposed that a concomitant generation of oxidative stress of oocytes with increasing maternal age may be a major factor responsible for the age-related increase in aneuploid conceptions. As a preliminary step in the testing of this hypothesis, we need to confirm that oxidative stress in itself can induce errors in chromosome segregation. In order to achieve this goal, germinal vesicle (GV)-stage mouse oocytes from unstimulated ICR and (C57BL x CBA) F1 hybrid female mice were matured in vitro for 9 h for metaphase I (MI) oocytes or 16 h for metaphase II (MII) oocytes in the presence of varying concentrations of the oxidizing agent tertiary-butyl hydroperoxide (tBH). MII…
Human exome and mouse embryonic expression data implicate ZFHX3, TRPS1, and CHD7 in human esophageal atresia
2020
Introduction Esophageal atresia with or without tracheoesophageal fistula (EA/TEF) occurs approximately 1 in 3.500 live births representing the most common malformation of the upper digestive tract. Only half a century ago, EA/TEF was fatal among affected newborns suggesting that the steady birth prevalence might in parts be due to mutational de novo events in genes involved in foregut development. Methods To identify mutational de novo events in EA/TEF patients, we surveyed the exome of 30 case-parent trios. Identified and confirmed de novo variants were prioritized using in silico prediction tools. To investigate the embryonic role of genes harboring prioritized de novo variants we perfor…
Pre- and postsynaptic type-1 cannabinoid receptors control the alterations of glutamate transmission in experimental autoimmune encephalomyelitis
2013
Type-1 cannabinoid receptors (CB1R) are important regulators of the neurodegenerative damage in multiple sclerosis (MS) and in experimental autoimmune encephalomyelitis (EAE). In GABAergic striatal neurons, CB1R stimulation exerts protective effects by limiting inflammation-induced potentiation of glutamate-mediated spontaneous excitatory postsynaptic currents (sEPSCs). Here we show that CB1R located on GABAergic or on glutamatergic neurons are differentially involved in the pre- and postsynaptic alterations of sEPSCs caused by EAE in the striatum. After induction of EAE, mice selectively lacking CB1R on GABAergic neurons (GABA-CB1R-KO) showed exacerbated alterations of sEPSC duration in GA…
Probabilistic Corner Detection for Facial Feature Extraction
2009
After more than 35 years of resarch, face processing is considered nowadays as one of the most important application of image analysis. It can be considered as a collection of problems (i.e., face detection, normalization, recognition and so on) each of which can be treated separately. Some face detection and face recognition techniques have reached a certain level of maturity, however facial feature extraction still represents the bottleneck of the entire process. In this paper we present a novel facial feature extraction approach that could be used for normalizing Viola-Jones detected faces and let them be recognized by an appearance-based face recognition method. For each observed featur…