Search results for "cb"

showing 10 items of 647 documents

Observation of $Z$ production in proton-lead collisions at LHCb

2014

The first observation of $Z$ boson production in proton-lead collisions at a centre-of-mass energy per proton-nucleon pair of $\sqrt{s_{NN}}=5~\text{TeV}$ is presented. The data sample corresponds to an integrated luminosity of $1.6~\text{nb}^{-1}$ collected with the LHCb detector. The $Z$ candidates are reconstructed from pairs of oppositely charged muons with pseudorapidities between 2.0 and 4.5 and transverse momenta above $20~\text{GeV}/c$. The invariant dimuon mass is restricted to the range $60-120~\text{GeV}/c^2$. The $Z$ production cross-section is measured to be \begin{eqnarray*} ��_{Z\to��^+��^-}(\text{fwd})&=&13.5^{+5.4}_{-4.0}\text{(stat.)}\pm1.2\text{(syst.)}~\text{nb} …

14.70.Hp - Z bosonProtonNuclear Theory01 natural sciencesPhysics Particles & FieldsHigh Energy Physics - ExperimentSettore FIS/04 - Fisica Nucleare e SubnucleareLuminosityHigh Energy Physics - Experiment (hep-ex)Heavy-ion collision[PHYS.HEXP]Physics [physics]/High Energy Physics - Experiment [hep-ex]Electroweak interaction; Forward physics; Heavy Ions; Heavy-ion collision; Particle and resonance productionElectroweak interactionHeavy IonsHeavy IonNuclear ExperimentQCBosonPhysics25.75.Dw - Relativistic heavy-ion collisions: Particle and resonance production; 14.70.Hp - Z bosons; 13.38.Dg - Decays of Z bosons; 12.15.-y - Electroweak interactionsPhysicsHIGH ENERGIES12.15.-y - Electroweak interactionsParticle physicsComputer Science::Computation and Language (Computational Linguistics and Natural Language and Speech Processing)13.38.Dg - Decays of Z bosons25.75.Dw - Relativistic heavy-ion collisions: Particle and resonance productionPhysical SciencesPARTON DISTRIBUTIONS; BOSON PRODUCTION; HIGH ENERGIES; NUCLEAR PDFS; DEUTERIUM; DECAYFísica nuclearProduction (computer science)14.70.Hp - Z bosonsParticle Physics - ExperimentNuclear and High Energy PhysicsParticle physicsNUCLEAR PDFS530 PhysicsDEUTERIUMFOS: Physical sciencesPhysics InstituteLHCb - Abteilung HofmannHadronsParticle and resonance production0103 physical sciencesElectroweak interaction; Forward physics; Heavy Ions; Heavy-ion collision; Particle and resonance production; Nuclear and High Energy PhysicsSDG 7 - Affordable and Clean Energy010306 general physicsForward physicLarge Hadron Collider (France and Switzerland)BOSON PRODUCTION/dk/atira/pure/sustainabledevelopmentgoals/affordable_and_clean_energyScience & TechnologyMuon010308 nuclear & particles physicshep-exComputer Science::Information RetrievalGran Col·lisionador d'Hadrons13.38.Dg - Decays of Z bosonPARTON DISTRIBUTIONSForward physicsHigh Energy Physics::ExperimentFísica de partículesExperimentsDECAYEnergy (signal processing)JHEP
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Cross-culturally approaching the cycling behaviour questionnaire (CBQ) : Evidence from 19 countries

2022

Given different advances in applied literature, risky and positive behaviours keep gaining ground as key contributors for riding safety outcomes. In this regard, the Cycling Behaviour Questionnaire (CBQ) represents one of the tools available to assess the core dimensions of cycling behaviour and their relationship with road safety outcomes from a behavioural perspective. Nevertheless, it has never been psychometrically approached through a cross-cultural perspective. Therefore, this study aimed to perform the cross-cultural validation of the CBQ, examining its psychometric properties, reliability indexes, validity insights and descriptive scores in 19 countries distributed across five regio…

212 Civil and construction engineeringriding behaviour515 PsychologyRiding behaviourcycling safetyTransportationUNESCO::CIENCIAS TECNOLÓGICASBehavioural questionnairesCBQRegionsAutomotive Engineeringbehavioural questionnairesregionsCycling safetyUrban cyclingApplied Psychologyurban cyclingCivil and Structural Engineering
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"Table 3" of "Charm-quark fragmentation fractions and production cross section at midrapidity in pp collisions at the LHC"

2022

Production cross section of charm-anticharm quark pairs per unity of rapidity at midrapidity $\mathrm{d}\sigma^{\mathrm{c\overline{c}}}/\mathrm{d}y|_{|y| < 0.5}$ in pp collisions at $\sqrt{s} = 2.76$, $5.02$, and $7$ TeV.

5020.0$\mathrm{d}\sigma^{\mathrm{ccbar}}/\mathrm{d}y|_{|y| < 0.5}$pp -> $\mathrm{ccbar}$ + X2760.0High Energy Physics::Phenomenology7000.0High Energy Physics::ExperimentNuclear Experiment
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Análisis cuantitativo del hueso alveolar y palatino en las zonas de colocación de minitornillos utilizando CBCT

2022

OBJETIVOS: La estabilidad de los minitornillos está relacionada con la calidad y cantidad ósea existente en el complejo craneofacial. En este estudio se analizaron, tanto en el maxilar como en la mandíbula, los espacios interradiculares, la cortical ósea vestibular, la anchura del proceso alveolar, así como el espesor del hueso palatino y la densidad ósea de la cortical. Las mediciones se realizaron utilizando el CBCT y se analizó la correlación existente de las mismas con el patrón facial, la clase esquelética, la edad y el sexo de los sujetos. MATERIAL Y MÉTODOS: 129 CBCTs fueron seleccionados de pacientes pertenecientes a la Clínica Odontológica de la Universitat de València. Se realizar…

:CIENCIAS MÉDICAS ::Cirugía ::Ortodoncia-Estomatología [UNESCO]UNESCO::CIENCIAS MÉDICAS ::Cirugía ::Ortodoncia-Estomatologíaminitornilloscbctestudio óseo
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Sistema de transferencia de datos en el instrumento TilePPr del proyecto TileCal

2017

El proyecto surge de la implementación del nuevo sistema de lectura de datos FELIX, que aprovecha los Transceptores Gigabit incorporados en las FPGA XC7VX485T y XC7VX690T del fabricante Xilinx. Estos transceptores se usan para establecer enlaces de datos a través de fibra óptica entre la FPGA del Pre-procesador del TileCal o TilePPr (XC7VX485T) y la placa electrónica que está conectada por PCIe al servidor local (XC7VX690T), por lo que el trabajo consiste en alcanzar los siguientes objetivos: a) Poner en marcha en la FPGA XC7VX485T del Pre-procesador o TilePPr la interfaz de transferencia de datos para que sea compatible con el nuevo sistema “Enlace de intercambio en el límite frontal” o FE…

:CIENCIAS TECNOLÓGICAS::Tecnología electrónica ::Diseño de circuitos [UNESCO]:CIENCIAS TECNOLÓGICAS::Tecnología electrónica ::Microelectrónica. Diseño [UNESCO]pcb:CIENCIAS TECNOLÓGICAS::Tecnología electrónica ::Microelectrónica [UNESCO]fpga Mezzanine Card:FÍSICA::Electrónica ::Circuitos integrados [UNESCO]placa de circuito impresoUNESCO::CIENCIAS TECNOLÓGICAS::Tecnología electrónica ::Diseño de circuitoscomunicación digitalvhdltransferencia de datosfpgaUNESCO::FÍSICA::Electrónica ::Circuitos integradosprotocolo de comunicaciónUNESCO::CIENCIAS TECNOLÓGICAS::Tecnología electrónica ::Microelectrónica. Diseñoelectrónica Digitalseñal de relojmicrostripUNESCO::CIENCIAS TECNOLÓGICAS::Tecnología electrónica ::Microelectrónicafield programmable gate arrays
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Latvijas Vēstures Institūta Žurnāls. 2015, Nr. 3 (96)

2015

Valsts kultūrkapitāla fonds

:HUMANITIES and RELIGION::History and philosophy subjects::Archaeology subjects [Research Subject Categories]:HUMANITIES and RELIGION::History and philosophy subjects::History subjects [Research Subject Categories]Latviešu un vācbaltieši starpkaru periodāRecenzijasZinātnes dzīveVēstures avotiLatvia in the Plans and Actions of Polish DiplomacySievietes un vara Padomju LatvijāLatvijas mazpilsētasPersonālijas
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El discurso profesional en la biblioteca: alternativas en red a la relación usuario-sistema

2020

Este trabajo analiza la relación entre bibliotecarios y usuarios partiendo de un enfoque que toma el texto generado por estos profesionales, no como una ventana a una realidad única, sino como objeto de análisis. Se trata del análisis del discurso, que permite adoptar una perspectiva crítica, cuestionando hechos ampliamente aceptados y reflexionando sobre el objeto de estudio, en este caso los usuarios de las bibliotecas.

:LINGÜÍSTICA::Lingüística aplicada::Documentación [UNESCO]information behaviourCB. User studies.UNESCO::LINGÜÍSTICA::Lingüística aplicada::Documentacióndiscourse analysis
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Pharmacological activation of CB2 receptors counteracts the deleterious effect of ethanol on cell proliferation in the main neurogenic zones of the a…

2015

Chronic alcohol exposure reduces endocannabinoid activity and disrupts adult neurogenesis in rodents, which results in structural and functional alterations. Cannabinoid receptor agonists promote adult neural progenitor cell (NPC) proliferation. We evaluated the protective effects of the selective CB1 receptor agonist ACEA, the selective CB2 receptor agonist JWH133 and the fatty-acid amide-hydrolase (FAAH) inhibitor URB597, which enhances endocannabinoid receptor activity, on NPC proliferation in rats with forced consumption of ethanol (10%) or sucrose liquid diets for 2 weeks. We performed immunohistochemical and stereological analyses of cells expressing the mitotic phosphorylation of his…

:Phenomena and Processes::Physiological Phenomena::Physiological Processes::Growth and Development::Morphogenesis::Embryonic and Fetal Development::Organogenesis::Neurogenesis [Medical Subject Headings]CB1 receptorTubulina (proteína)Cannabinoid receptorCarbamatosEtanol:Chemicals and Drugs::Amino Acids Peptides and Proteins::Proteins::Nuclear Proteins::Histones [Medical Subject Headings]Ventrículos lateralesSacarosaNeuronasSubgranular zone0302 clinical medicine:Chemicals and Drugs::Amino Acids Peptides and Proteins::Proteins::Membrane Proteins::Receptors Cell Surface::Receptors G-Protein-Coupled::Receptors Cannabinoid::Receptor Cannabinoid CB1 [Medical Subject Headings]Histonas:Chemicals and Drugs::Organic Chemicals::Carboxylic Acids::Acids Acyclic::Carbamates [Medical Subject Headings]Receptor cannabinoide CB1Cannabinoid receptor type 2:Organisms::Eukaryota::Animals [Medical Subject Headings]:Phenomena and Processes::Metabolic Phenomena::Metabolism::Phosphorylation [Medical Subject Headings]:Anatomy::Cells::Stem Cells::Neural Stem Cells [Medical Subject Headings]:Anatomy::Nervous System::Neurons [Medical Subject Headings]health care economics and organizations:Anatomy::Nervous System::Central Nervous System::Brain::Cerebral Ventricles::Lateral Ventricles [Medical Subject Headings]Original Research:Chemicals and Drugs::Nucleic Acids Nucleotides and Nucleosides::Nucleosides::Deoxyribonucleosides::Deoxyuridine::Bromodeoxyuridine [Medical Subject Headings]0303 health sciencesAlcoholismoalcoholConsumo de alcoholNeurogenesis:Phenomena and Processes::Genetic Phenomena::Phenotype::Genetic Markers [Medical Subject Headings]:Chemicals and Drugs::Chemical Actions and Uses::Pharmacologic Actions::Molecular Mechanisms of Pharmacological Action::Neurotransmitter Agents::Cannabinoid Receptor Modulators::Cannabinoid Receptor Agonists [Medical Subject Headings]Benzamidas:Chemicals and Drugs::Amino Acids Peptides and Proteins::Proteins::Membrane Proteins::Receptors Cell Surface::Receptors G-Protein-Coupled::Receptors Cannabinoid::Receptor Cannabinoid CB2 [Medical Subject Headings]Endocannabinoid system3. Good healthbromodesoxiuridinaneurogenesisEndocannabinoidesmedicine.anatomical_structure:Chemicals and Drugs::Enzymes and Coenzymes::Enzymes::Hydrolases [Medical Subject Headings]ACEADietaAlcoholFosforilaciónAgonistmedicine.medical_specialtyHidrolasasmedicine.drug_classNeurogenesiseducation:Psychiatry and Psychology::Mental Disorders::Substance-Related Disorders::Alcohol-Related Disorders::Alcoholism [Medical Subject Headings]Subventricular zoneBiology:Phenomena and Processes::Physiological Phenomena::Nutritional Physiological Phenomena::Diet [Medical Subject Headings]:Anatomy::Nervous System::Central Nervous System::Brain::Prosencephalon::Telencephalon::Cerebrum::Cerebral Cortex::Hippocampus::Dentate Gyrus [Medical Subject Headings]lcsh:RC321-57103 medical and health sciencesCellular and Molecular NeuroscienceRatasInternal medicine:Chemicals and Drugs::Amino Acids Peptides and Proteins::Proteins::Nerve Tissue Proteins::Tubulin [Medical Subject Headings]JWH133medicineGiro dentadolcsh:Neurosciences. Biological psychiatry. Neuropsychiatry030304 developmental biologyCélulas madre nerviosas:Chemicals and Drugs::Chemical Actions and Uses::Pharmacologic Actions::Molecular Mechanisms of Pharmacological Action::Neurotransmitter Agents::Endocannabinoids [Medical Subject Headings]Dentate gyrusmarcadores genéticosCB2 receptor:Chemicals and Drugs::Carbohydrates::Polysaccharides::Oligosaccharides::Disaccharides::Sucrose [Medical Subject Headings]:Anatomy::Nervous System::Central Nervous System::Brain::Prosencephalon::Diencephalon::Hypothalamus [Medical Subject Headings]:Chemicals and Drugs::Organic Chemicals::Alcohols::Ethanol [Medical Subject Headings]Endocrinology:Organisms::Eukaryota::Animals::Chordata::Vertebrates::Mammals::Rodentia::Muridae::Murinae::Rats [Medical Subject Headings]nervous system:Psychiatry and Psychology::Behavior and Behavior Mechanisms::Behavior::Drinking Behavior::Alcohol Drinking [Medical Subject Headings]:Chemicals and Drugs::Organic Chemicals::Amides::Benzamides [Medical Subject Headings]030217 neurology & neurosurgeryHipotálamoNeuroscience
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Efficacy of an internet-based psychological intervention for problem gambling and gambling disorder: study protocol for a randomized controlled trial

2021

Gambling Disorder is a prevalent non-substance use disorder, which contrasts with the low number of people requesting treatment. Information and Communication Technologies (ICT) could help to enhance the dissemination of evidence-based treatments and considerably reduce the costs. The current study seeks to assess the efficacy of an online psychological intervention for people suffering from gambling problems in Spain. The proposed study will be a two-arm, parallel-group, randomized controlled trial. A total of 134 participants (problem and pathological gamblers) will be randomly allocated to a waiting list control group (N = 67) or an intervention group (N = 67). The intervention program i…

A ActionDGOJ Directorate General for the Regulation of GamblingCIDI Composite International Diagnostic InterviewPA Positive AffectSPIRIT Standard Protocol Items Recommendations for Interventional TrialsefficacyPsychological interventionMotivational interviewingGE Gambling ExpectanciesDSM-IV Diagnostic and Statistical Manual of Mental Disorders Fourth EditionOASIS The Overall Anxiety Severity and Impairment Scalelaw.inventionDERS Difficulties in Emotion Regulation ScaleRandomized controlled triallawPANAS The Positive and Negative Affect SchedulePsychologyRCT Randomized Controlled TrialUPPS-P The Short UPPS-P Impulsivity ScaleICD-10 International Statistical Classification of Diseases and Related Health Problems 10th RevisionCognitionT58.5-58.64GRCS-S Gambling-Related Cognitions ScalePC Predictive ControlBF1-990EDBs Emotion Driven BehavioursC ContemplationGSEQ Gambling Self-Efficacy QuestionnaireDSM-5 Diagnostic and Statistical Manual of Mental Disorders Fifth EditionAnxietyAddicció a Internetmedicine.symptomMI Motivational InterviewingPsychologyJocs per ordinadorM Maintenancemedicine.medical_specialtyemotion regulationG-SAS The Gambling Symptom Assessment ScaleEMA Ecological Momentary AssessmentODSIS The Overall Depression Severity and Impairment ScaleEfficacyWL Waiting ListIC Illusion of ControlIB Interpretative BiasMFS Monitoring Feedback and SupportCBTHealth InformaticsInformation technologyCBT Cognitive Behavioral TherapyImpulsivityCONSORT-EHEALTH Consolidated Standards of Reporting Trials of Electronic and Mobile Health Applications and Online TelehealthISG Perceived Inability to Stop GamblingQuality of life (healthcare)URICA The University of Rhode Island Change Assessment ScaleIntervention (counseling)medicineGD Gambling DisorderSCID-P The Structured Clinical InterviewPsychiatryQLI Quality Life IndexInternetEmotion regulationFull length ArticleSUS System Usability ScalegamblingEMI Ecological Momentary InterventionMINI Mini International Neuropsychiatric InterviewGI Gambling history interview and current gambling situation and related variables assessmentNA Negative AffectGamblingNODS NORC DSM-IV Screen for Gambling ProblemsPFIs Personal Feedback InterventionsDSM-III-R Diagnostic and Statistical Manual of Mental Disorders 3rd Edition RevisedHADS Hospital Anxiety Depression ScaleinternetP Precontemplation
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Polyoxypregnanes as safe, potent, and specific ABCB1-inhibitory pro-drugs to overcome multidrug resistance in cancer chemotherapy in vitro and in vivo

2021

Multidrug resistance (MDR) mediated by ATP binding cassette subfamily B member 1 (ABCB1) is significantly hindering effective cancer chemotherapy. However, currently, no ABCB1-inhibitory drugs have been approved to treat MDR cancer clinically, mainly due to the inhibitor specificity, toxicity, and drug interactions. Here, we reported that three polyoxypregnanes (POPs) as the most abundant constituents of Marsdenia tenacissima (M. tenacissima) were novel ABCB1-modulatory pro-drugs, which underwent intestinal microbiota-mediated biotransformation in vivo to generate active metabolites. The metabolites at non-toxic concentrations restored chemosensitivity in ABCB1-overexpressing cancer cells v…

ABCC1 ATP binding cassette subfamily C member 1IC50 half maximal inhibitory concentrationMultidrug resistancePharmacologyNADPH reduced nicotinamide adenine dinucleotide phosphateF bioavailabilitychemistry.chemical_compoundPCR polymerase chain reaction0302 clinical medicineMDR multidrug resistanceECL electrochemiluminescencet1/2 elimination half-lifeLC–MS liquid chromatography coupled with mass spectrometryN.D. not detectedGeneral Pharmacology Toxicology and PharmaceuticsBBB blood–brain barriermedia_commonATF3 activating transcription factor 30303 health sciencesChemistryABC ATP-binding cassetteNMPA National Medical Products AdministrationPXR pregnane X receptorSDS-PAGE sodium dodecyl sulfate-polyacrylamide gel electrophoresisHBSS Hankʹs balanced salt solutionABCB1Combination chemotherapyProdrugMarsdenia tenacissimaCmax peak concentrationPaclitaxelGAPDH glyceraldehyde-3-phosphate dehydrogenase030220 oncology & carcinogenesisBHI brain heart infusionOriginal ArticleAUC0–∞ area under plasma concentration vs. time curveMRT mean residence timeDrugmedia_common.quotation_subjectRM1-950Vd volume of distributionABCB1 ATP binding cassette subfamily B member 1UIC-2 mouse monoclonal ABCB1 antibodyABCG2 ATP binding cassette subfamily G member 2Combination chemotherapyCYP cytochrome P450 isozymePI propidium iodideTEER transepithelial electrical resistance03 medical and health sciencesPBS phosphate buffer salineFBS fetal bovine serumDox doxorubicinIn vivoPOP polyoxypregnanemedicine030304 developmental biologyEVOM epithelial tissue voltohmmeterTmax time for peak concentrationCancerLBE lowest binding energyPE phycoerythrinmedicine.diseaseMultiple drug resistancePolyoxypregnanePapp apparent permeabilityN.A. not applicableCancer cellH&E hematoxylin and eosinMDR1a multidrug resistance protein 1aTherapeutics. PharmacologyqPCR quantitative PCRM. tenacissima Marsdenia tenacissimaCL clearanceSD standard derivationActa Pharmaceutica Sinica B
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