Search results for "cervical"
showing 10 items of 511 documents
The Impact of Single-Level ACDF on Neural Foramen and Disc Height of Surgical and Adjacent Cervical Segments: A Case-Series Radiological Analysis
2023
Background: ACDF has become one of the established procedures for the surgical treatment of symptomatic cervical spondylosis, showing excellent clinical results and effective improvements in neural functions and neck pain relief. The main purpose of ACDF is neural decompression, and it is considered by some authors as an indirect result of the intervertebral distraction and cage insertion and the consequent restoration of the disc space and foramen height. Methods: Radiological data from 28 patients who underwent single-level ACDF were retrospectively collected and evaluated. For neural foramen evaluation, antero-posterior (A-P) and cranio-caudal (C-C) diameters were manually calculated; fo…
Role of laparoscopic hysterectomy in cervical and endometrial cancer: a narrative review
2022
Endometrial cancer is the most common carcinoma of the female genital organs and cervical cancer is the leading cause of cancer death in women worldwide. The aim of this review is to evaluate the role of laparoscopic hysterectomy in patients with endometrial and cervical cancer in this period, and analyze the outcome of hysterectomy in terms of survival. Moreover, we present the historical background, new techniques, the anatomical features, and surgical steps of radical hysterectomy. According to new evidence, minimally invasive surgery in patients with cervical cancer is associated with higher rates of recurrence and mortality compared to the open approach. Despite the numerous explanatio…
Expression of p63, p53 and ki-67 in patients with cervical intraepithelial neoplasia
2017
Objective: Cervical intraepithelial neoplasia (CIN) is a dysplastic process in cervical squamous epithelium and carries a risk of progression to cervical cancer. The aim of this study was to compare expression of three biomarkers named p53, p63 and Ki-67 in patients with various grades of cervical intraepithelial neoplasia and in a control group. Material and Method: 58 patients were enrolled in the study. Each patient underwent a colposcopy-guided biopsy of the cervix. Immunostaining for markers (p53, p63 and Ki-67) was performed on tissue samples of normal cases (n=10), CIN I (n=20), CIN II (n=14), and CIN III (n=14). Results: Our study showed a significant increase of the expression of t…
Estudio biomecánico y correlación clínica de los sistemas de artrodesis cervical anterior caja-placa
2021
Nº Tesis 12712 dentro del Programa de Medicina del Departamento de Cirugía de la Facultad de Medicina y Odontología de la Universidad de Valencia Tutor: Guillermo García-March. Fecha de lectura: 24 de septiembre de 2021. Calificación. Sobresaliente cum laude.
Predicción del parto prematuro en reproducción asistida : la importancia del cérvix
2014
Introducción El parto pretermino es aquel que acontece antes de la semana 37 y después de la semana 23 de gestación. A pesar de los avances de medicina perinatal no se ha conseguido disminuir esa cifra, es más, se ha producido un aumento en países desarrollados, gracias al incremento de las técnicas de reproducción asistida que generan un aumento de las gestaciones múltiples pero también gestaciones únicas de mayor riesgo. La patogénesis del parto pretérmino es aún discutida, y no está claro si representa una activación temprana e idiopática del trabajo de parto normal o es el resultado de algún mecanismo patológico. La detección y el intento de predicción del parto dependen de la identific…
Evaluation of Surgical Outcomes of Abdominal Radical Hysterectomy and Total Laparoscopic Radical Hysterectomy for Cervical Cancer: A Retrospective An…
2022
Although a surgical approach is one of the key treatments for stages IA1-IIA2, results of the Laparoscopic Approach to Cervical Cancer (LACC) published in 2018 radically changed the field, since minimally invasive surgery was associated with a four-fold higher rate of recurrence and a six-fold higher rate of all-cause death compared to an open approach. We aimed to evaluate surgical outcomes of abdominal radical hysterectomy (ARH) and total laparoscopic radical hysterectomy (TLRH) for cervical cancer, including data collected before the LACC trial. In our retrospective analysis, operative time was significantly longer in TLRH compared to ARH (p < 0.0001), although this disadvantage could…
Role of post mortem computed tomography in diagnosis of upper cervical fractures in child due to road accident: A case report and literature review
2019
The upper cervical spine has unique anatomical features that distinguish it from the remainder of the cervical spine. Its motion segments make up a large amount of total cervical spine motion and, as a result,predispose it to a unique set of injuries. Cervical spine trauma is a common problem with a wide range of severity from minor ligamentous injury to section of the spinal cord. The use of post mortem CT (PMCT), and the subsequent multi-planar and volume rendering reconstruction techniques can provide non-invasive, objective operator-independent imaging data set that may be further reviewed by other specialists. and can substantially add to forensic examinations of the skeleton, especial…
Human Papillomavirus Type 16 E7 Peptide-Directed CD8+ T Cells from Patients with Cervical Cancer Are Cross-Reactive with the Coronavirus NS2 Protein
2003
ABSTRACTHuman papillomavirus type 16 (HPV16) E6 and E7 oncoproteins are required for cellular transformation and represent candidate targets for HPV-specific and major histocompatibility complex class I-restricted CD8+-T-cell responses in patients with cervical cancer. Recent evidence suggests that cross-reactivity represents the inherent nature of the T-cell repertoire. We identified HLA-A2 binding HPV16 E7 variant peptides from human, bacterial, or viral origin which are able to drive CD8+-T-cell responses directed against wild-type HPV16 E7 amino acid 11 to 19/20 (E711-19/20) epitope YMLDLQPET(T) in vitro. CD8+T cells reacting to the HLA-A2-presented peptide from HPV16 E711-19(20)recogni…
A short introduction to papillomavirus biology.
2003
In this report, the tropism of papillomaviruses, the structure of virions, the function of viral proteins and the use of pseudovirions for the analysis of the immune response against papillomaviruses and the search for the viral receptor are briefly described.
Estudio de los defectos congénitos del arco anterior, arco posterior y foramen transversarium de C1
2015
La primera vértebra cervical (atlas) se caracteriza por presentar rasgos anatómicos diferentes al resto de las vértebras cervicales, no tiene cuerpo ni apófisis espinosa, sino que muestra una morfología anular, con dos arcos (anterior y posterior) y dos masas laterales. Las alteraciones congénitas del arco posterior del atlas son poco frecuentes, habiéndose publicado frecuencias entre 0,73% y 4%, casi siempre asintomáticas, por lo que se diagnostican incidentalmente. Sin embargo, también se ha descrito una amplia variedad de sintomatología asociada, relacionada o no con antecedentes traumáticos, desde cervicalgia crónica, cefalea, signo de Lhermitte secundario a estenosis cervical sobre tod…