Search results for "changing"

showing 10 items of 96 documents

Decreased glutathione peroxidase activity in sciatic nerve of alloxan-induced diabetic mice and its correlation with blood glucose levels.

1993

The effect of alloxan-induced diabetes on glutathione peroxidase (GSH-Px) activity in sciatic nerve of mice has been studied. We have found, 7 days after alloxan treatment, a significant decrease in this enzymatic activity in the cytosol of sciatic nerve of diabetic mice, and moreover, that these changes remained unaltered up to 21 days after alloxan injection. No modification in the glutathione content of sciatic nerve of diabetic mice was observed throughout the experiment when compared with controls. The decrease in GSH-Px activity in this tissue shows a good correlation with the increase of blood glucose levels throughout the experiment. It is hypothesized whether a combination of mecha…

Blood GlucoseMalemedicine.medical_specialtyDiabetic neuropathyFree RadicalsRatónBiochemistryDiabetes Mellitus ExperimentalCellular and Molecular Neurosciencechemistry.chemical_compoundMiceCytosolInternal medicineDiabetes mellitusAlloxanmedicineAnimalschemistry.chemical_classificationGlutathione PeroxidaseChemistryGlutathione peroxidaseGeneral MedicineGlutathionemedicine.diseaseSciatic NervePeripheral neuropathyEndocrinologySciatic nerveSodium-Potassium-Exchanging ATPaseNeurochemical research
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How do drought and rain events impact soil microbial communities greenhouse gas production?

2011

Affiche, résumé. Session GC: Microbes in the Changing Environmenl: Global Climate Change and Soil under Human Impact; International audience

CONSEQUENCE POUR LA POPULATION[SDV] Life Sciences [q-bio][SDE] Environmental SciencesCHANGING ENVIRONMENTCHANGEMENT DU CLIMATHUMAN IMPACT[SDV]Life Sciences [q-bio][SDE]Environmental SciencesBIOGEOCHEMICALComputingMilieux_MISCELLANEOUSCOMMUNAUTE MICROBIALE
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Evidence for a selective and electroneutral K+/H+-exchange in Saccharomyces cerevisiae using plasma membrane vesicles

1996

The existence of a K+/H+ transport system in plasma membrane vesicles from Saccharomyces cerevisiae is demonstrated using fluorimetric monitoring of proton fluxes across vesicles (ACMA fluorescence quenching). Plasma membrane vesicles used for this study were obtained by a purification/reconstitution protocol based on differential and discontinuous sucrose gradient centrifugations followed by an octylglucoside dilution/gel filtration procedure. This method produces a high percentage of tightly-sealed inside-out plasma membrane vesicles. In these vesicles, the K+/H+ transport system, which is able to catalyse both K+ influx and efflux, is mainly driven by the K+ transmembrane gradient and ca…

Cell Membrane Permeability[SDV]Life Sciences [q-bio]Coated VesiclesCoated vesicleBiological Transport ActiveBioengineeringSaccharomyces cerevisiaeBiologyH(+)-K(+)-Exchanging ATPaseApplied Microbiology and BiotechnologyBiochemistryMembrane PotentialsCell membraneElectron Transport Complex IVH(+)-K(+)-Exchanging ATPasealpha-MannosidaseMannosidasesGeneticsmedicineCentrifugation Density GradientNa+/K+-ATPaseComputingMilieux_MISCELLANEOUSMembrane potentialVesicleCell MembraneDithiazanineElectron Transport Complex IVIsoxazolesHydrogen-Ion ConcentrationMembranemedicine.anatomical_structureSpectrometry Fluorescence[SDV.MP]Life Sciences [q-bio]/Microbiology and ParasitologyBiochemistryBiophysicsChromatography GelPotassiumProtonsMannoseBiotechnology
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How to engineer biologically inspired cognitive architectures

2013

Biologically inspired cognitive architectures are complex systems where different modules of cognition interact in order to reach the global goals of the system in a changing environment. Engineering and modeling this kind of systems is a hard task due to the lack of techniques for developing and implementing features like learning, knowledge, experience, memory, adaptivity in an inter-modular fashion. We propose a new concept of intelligent agent as abstraction for developing biologically cognitive architectures. © 2013 Springer-Verlag.

Cognitive systemsComputer scienceBiologically inspiredComplex systemCognitionCognitive architecturecomputer.software_genreCognitive architectureTask (project management)Biologically inspired cognitive architecturedesign processIntelligent agentAdaptivityChanging environmentHuman–computer interactionHard taskcomputerSocial simulationAbstraction (linguistics)
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Search for flavor changing neutral currents in decays of top quarks

2011

We present a search for flavor changing neutral currents in decays of top quarks. The analysis is based on a search for ttbar -> l'null + jets (l, l' = e, mu) final states using 4.1 fb^-1 of integrated luminosity of ppbar collisions at sqrt(s) = 1.96 TeV. We extract limits on the branching ratio B(t -> Zq) (q = u, c quarks), assuming anomalous tuZ or tcZ couplings. We do not observe any sign of such anomalous coupling and set a limit of B < 3.2% at 95% C.L.

CouplingPhysicsQuarkNuclear and High Energy PhysicsTop quarkParticle physicsLuminosity (scattering theory)010308 nuclear & particles physicsBranching fractionFlavor-changing neutral currentHigh Energy Physics::PhenomenologyTevatronFOS: Physical sciences01 natural sciencesHigh Energy Physics - ExperimentNuclear physicsHigh Energy Physics - Experiment (hep-ex)0103 physical sciencesExperimental High Energy PhysicsComputingMethodologies_DOCUMENTANDTEXTPROCESSING[PHYS.HEXP]Physics [physics]/High Energy Physics - Experiment [hep-ex]High Energy Physics::Experiment010306 general physicsSign (mathematics)
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Cytotoxicity of cardiotonic steroids in sensitive and multidrug-resistant leukemia cells and the link with Na(+)/K(+)-ATPase.

2015

Cardiotonic steroids have long been in clinical use for treatment of heart failure and are now emerging as promising agents in various diseases, especially cancer. Their main target is Na(+)/K(+)-ATPase, a membrane protein involved in cellular ion homeostasis. Na(+)/K(+)-ATPase has been implicated in cancer biology by affecting several cellular events and signaling pathways in both sensitive and drug-resistant cancer cells. Hence, we investigated the cytotoxic activities of 66 cardiotonic steroids and cardiotonic steroid derivatives in sensitive CCRF-CEM and multidrug-resistant CEM/ADR5000 leukemia cells. Data were then subjected to quantitative structure-activity relationship analysis (QSA…

DigoxinCell SurvivalEndocrinology Diabetes and MetabolismClinical BiochemistryPrimary Cell CultureGene ExpressionQuantitative Structure-Activity RelationshipAntineoplastic AgentsBiologyPharmacologyBiochemistryCardiac GlycosidesEndocrinologyCellular ion homeostasisCell Line TumorCytotoxic T cellHumansNa+/K+-ATPaseCytotoxicityMolecular BiologyCell BiologyMolecular biologyDrug Resistance MultipleBlotBufanolidesMolecular Docking SimulationVerapamilCell cultureDoxorubicinDrug Resistance NeoplasmCancer cellLeukocytes MononuclearMolecular MedicineSignal transductionSodium-Potassium-Exchanging ATPaseSignal TransductionThe Journal of steroid biochemistry and molecular biology
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Effect of a hyperlipidic diet on lipid composition, fluidity, and (Na+-K+)ATPase activity of rat erythrocyte membranes.

1989

Feeding rats a hyperlipidic diet in which animals were offered daily a variety of high-energy food resulted in a significant increase of serum free fatty acids and a decrease of phospholipids with respect to controls. On the contrary, there were no significant differences in erythrocyte membrane total lipid composition between the two groups. Erythrocyte membranes showed a significant decrease in saturated fatty acid content and a significant increase in (n-6) polyunsaturated fatty acid content; (n-3) polyunsaturated fatty acids significantly decreased. Membrane fluidity, investigated by fluorescence polarization of diphenylhexatriene, significantly increased in the erythrocyte membranes of…

DiphenylhexatrieneMalemedicine.medical_specialtyChromatography GasMembrane FluidityBiochemistrychemistry.chemical_compoundEatingInternal medicinemedicineMembrane fluidityAnimalsNa+/K+-ATPaseUnsaturated fatty acidchemistry.chemical_classificationErythrocyte MembraneFatty AcidsDietary FatsLipidsDietRatsEndocrinologyMembranechemistryBiochemistrySaturated fatty acidSodium-Potassium-Exchanging ATPaseFluorescence anisotropyPolyunsaturated fatty acidMembrane biochemistry
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Multiple solutions for quasilinear elliptic problems via critical points in open sublevels and truncation principles

2012

Abstract We study a quasilinear elliptic problem depending on a parameter λ of the form − Δ p u = λ f ( u ) in  Ω , u = 0 on  ∂ Ω . We present a novel variational approach that allows us to obtain multiplicity, regularity and a priori estimate of solutions by assuming certain growth and sign conditions on f prescribed only near zero. More precisely, we describe an interval of parameters λ for which the problem under consideration admits at least three nontrivial solutions: two extremal constant-sign solutions and one sign-changing solution. Our approach is based on an abstract localization principle of critical points of functionals of the form E = Φ − λ Ψ on open sublevels Φ − 1 ( ] − ∞ , …

Extremal constant-sign solutionApplied Mathematicsp-LaplacianMathematical analysisMountain pass theoremCritical pointsExtremal constant-sign solutionsMultiplicity (mathematics)A priori estimateSign-changing solutionsAnalysisCritical pointMathematicsJournal of Mathematical Analysis and Applications
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A survey on pseudonym changing strategies for Vehicular Ad-Hoc Networks

2017

International audience; The initial phase of the deployment of vehicular ad-hoc networks (VANETs) has begun and many research challenges still need to be addressed. Location privacy continues to be in the top of these challenges. Indeed, both academia and industry agreed to apply the pseudonym changing approach as a solution to protect the location privacy of VANETs' users. However, due to the pseudonyms linking attack, a simple changing of pseudonym shown to be inefficient to provide the required protection. For this reason, many pseudonym changing strategies have been suggested to provide an effective pseudonym changing. Unfortunately, the development of an effective pseudonym changing st…

FOS: Computer and information sciencesComputer Science - Cryptography and SecurityComputer scienceWireless ad hoc networklocation privacy02 engineering and technologysecurityPseudonymComputer securitycomputer.software_genre[SPI]Engineering Sciences [physics]0203 mechanical engineeringpseudonym changing0202 electrical engineering electronic engineering information engineeringVANETsElectrical and Electronic EngineeringAuthenticationVehicular ad hoc networksAuthenticationComputerSystemsOrganization_COMPUTER-COMMUNICATIONNETWORKS020206 networking & telecommunications020302 automobile design & engineeringRoadsSoftware deploymentPrivacyInitial phaseComputingMilieux_COMPUTERSANDSOCIETYSafetycomputerCryptography and Security (cs.CR)
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Observation of Photon Polarization in theb→sγTransition

2014

This Letter presents a study of the flavor-changing neutral current radiative $B^{\pm} \to K^{\pm}\pi^{\mp}\pi^{\pm}\gamma$ decays performed using data collected in proton-proton collisions with the LHCb detector at $7$ and $8\,$TeV center-of-mass energies. In this sample, corresponding to an integrated luminosity of $3\,\text{fb}^{-1}$, nearly $14\,000$ signal events are reconstructed and selected, containing all possible intermediate resonances with a $K^{\pm}\pi^{\mp}\pi^{\pm}$ final state in the $[1.1, 1.9]\,$GeV/$c^{2}$ mass range. The distribution of the angle of the photon direction with respect to the plane defined by the final-state hadrons in their rest frame is studied in interva…

Final statePhotonmedia_common.quotation_subject14.40.NdHadronGeneral Physics and AstronomyLHCb - Abteilung Hofmann12.15.MmAsymmetryHigh energy physics Polarization Tellurium compounds; Center-of-mass energies Direct observations Final state Flavor-changing neutral current Integrated luminosity Photon polarization Proton proton collisions; PhotonsNeutral currentNuclear physicsTellurium compoundsCenter-of-mass energiesPhysics and Astronomy (all)Flavor-changing neutral currentPolarizationPhoton polarizationLeptonic semileptonic and radiative decays of bottom mesonRadiative transferIntermediate stateSDG 7 - Affordable and Clean EnergyHigh energy physicsQCmedia_commonPhysicsIntegrated luminosityPhotons/dk/atira/pure/sustainabledevelopmentgoals/affordable_and_clean_energyProton proton collisionsNeutral currentDirect observationsParticle physicsRest framePhoton polarizationLHCb13.20.HeBottom mesons (|B|>0)High Energy Physics::ExperimentLHCFísica de partículesExperimentsPhysical Review Letters
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