Search results for "chemical stability"

showing 10 items of 96 documents

Physico-Chemical Stability of Admixtures of Vinflunine Used in Clinical Practice.

2021

Procedure of administration of vinflunine is complex and consists of an Y-site injection with fluid at different speeds. Dose is diluted with 100 mL of 0.9% sodium chloride or 5% glucose and infused with half of the 500 mL bag of the fluid over 20 min; after that, the remaining fluid is administered at 300 mL/h. In this study, chemical stability and physical compatibility of vinflunine diluted with in 500 mL of both fluids were evaluated to simplify the administration procedure (infusion of mixture on 20 min followed by 250 mL of fluid at 300 mL/h). Physical compatibility and chemical stability were evaluated at two temperatures and protected from and exposed to light. Physical compatibilit…

SodiumPharmaceutical ScienceExpiration datechemistry.chemical_element02 engineering and technologySodium ChlorideVinblastine030226 pharmacology & pharmacy03 medical and health scienceschemistry.chemical_compound0302 clinical medicineDrug StabilityChromatography High Pressure LiquidChromatographyVinflunineChemistryTemperatureVinflunine021001 nanoscience & nanotechnologyDilutionClinical PracticeAdministrationGravimetric analysisChemical stability0210 nano-technologyChemical stabilityPhysical compatibilityJournal of pharmaceutical sciences
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Advances in the investigation of dioxouranium(VI) complexes of interest for natural fluids

2012

Abstract The interactions of dioxouranium(VI) cation with different organic and inorganic ligands of environmental and biological interest were carefully examined with the aim to draw a chemical speciation picture of this ion in natural aquatic ecosystems and in biological fluids. Since UO22+ ion shows a significant tendency to hydrolyze, particular attention was paid in considering the hydrolysis species formation both in the presence and in absence of ligands. The results reported in the literature show that formation of the hydrolytic species assumes a great importance in the complexation models for all the UO22+-ligand systems considered. In particular, the following ligands have been t…

SpeciationDioxouranium(VI) complexes; Aqueous solutions; Inorganic ligands; Organic ligands; Speciation; SequestrationOrganic ligandsInorganic Chemistrychemistry.chemical_compoundComputational chemistryMaterials ChemistryAqueous solutionDioxouranium(VI) complexesOrganic chemistryMoleculeSettore CHIM/01 - Chimica AnaliticaCarboxylatePhysical and Theoretical ChemistryBinding siteAqueous solutionsDioxouranium(VI) complexechemistry.chemical_classificationInorganic ligandsAqueous solutionLigandSequestrationInorganic ligandUranylAmino acidchemistryOrganic ligandChemical stabilityCoordination Chemistry Reviews
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Formation in solution, synthesis and crystal structure of μ-oxalatobis[bis(2-pyridylcarbonyl)amido] dicopper(II)

1989

Abstract The compound μ-oxalatobis[bis(2-pyridylcarbonyl)amido] dicopper(II), [Cu 2 {(NCsH 5 CO) 2 N} 2 - (C 2 O 4 )] was synthesized and characterized by spectroscopy, EPR and diffraction methods. It crystallizes in the triclinic space group P 1 with cell constants: a =7.6793(6), b =9.238(2), c =10.007(2) A, α=83.80(1), β=68.37(1) and γ=69.44(1)°; V =617.7(3) A 3 , D (calc., Z =2)=1.80 g cm −3 , M r =667.6, F (000)=336, λ, (Mo Kα)=0.71069 A, μ (Mo Kα)=17.895 cm −1 and T =295 K. A total of 3587 data were collected over the range of 1 ⩽ θ ⩽ 30°; of these, 2391 (independent and with I⩾2σ( I )) were used in the structural analysis. The final R and R w residuals were 0.049 and 0.053, respective…

StereochemistryCrystal structureTriclinic crystal systemOxalatelaw.inventionInorganic Chemistrychemistry.chemical_compoundCrystallographyPerchloratechemistrylawX-ray crystallographyMaterials ChemistryMoleculeChemical stabilityPhysical and Theoretical ChemistryElectron paramagnetic resonanceInorganica Chimica Acta
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A unified view of ligand-protected gold clusters as superatom complexes

2008

Synthesis, characterization, and functionalization of self-assembled, ligand-stabilized gold nanoparticles are long-standing issues in the chemistry of nanomaterials. Factors driving the thermodynamic stability of well documented discrete sizes are largely unknown. Herein, we provide a unified view of principles that underlie the stability of particles protected by thiolate (SR) or phosphine and halide (PR 3 , X) ligands. The picture has emerged from analysis of large-scale density functional theory calculations of structurally characterized compounds, namely Au 102 (SR) 44 , Au 39 (PR 3 ) 14 X 6 − , Au 11 (PR 3 ) 7 X 3 , and Au 13 (PR 3 ) 10 X 2 3+ , where X is either a halogen or a thiol…

Steric effectsMultidisciplinaryChemistryComputational chemistryLigandSuperatomPhysical SciencesCluster (physics)MoleculeDensity functional theoryNanotechnologyChemical stabilityNanoclusters
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Solvent-free ball-milling subcomponent synthesis of metallosupramolecular complexes.

2015

Subcomponent self-assembly from components A, B, C, D, and Fe(2+) under solvent-free conditions by self-sorting leads to the construction of three structurally different metallosupramolecular iron(II) complexes. Under carefully selected ball-milling conditions, tetranuclear [Fe4 (AD2 )6 ](4-) 22-component cage 1, dinuclear [Fe2 (BD2 )3 ](2-) 11-component helicate 2, and 5-component mononuclear [Fe(CD3 )](2+) complex 3 were prepared simultaneously in a one-pot reaction from 38 components. Through subcomponent substitution reaction by adding subcomponent B, the [Fe4 (AD2 )6 ](4-) cage converts quantitatively to the [Fe2 (BD2 )3 ](2-) helicate, which, in turn, upon addition of subcomponent C, …

Substitution reactionSolvent freeChemistryStereochemistryOrganic ChemistrySupramolecular chemistryGeneral ChemistryCatalysisball millself-sortingsupramolecular chemistryTurn (biochemistry)CrystallographySelf sortingMechanochemistrymulticomponent synthesisdynamic imine chemistryChemical stabilitymechanochemistryBall millta116Chemistry (Weinheim an der Bergstrasse, Germany)
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Geminal Imidazolium Salts: A new Class of Gelators

2012

The gelling behavior of some geminal diimidazolium salts was investigated in solvents differing in polarity and hydrogen bond donor ability. The used salts, namely the 3,3'-di-n-decyl-1,1'(1,4-phenylenedimethylene)diimidazolium dibromide [p-Xyl-(decim)(2)][Br](2) (1), the 3,3'-di-n-dodecyl-1,1'(1,4-phenylenedimethylene)diimidazolium dibromide [p-Xyl-(dodecim)(2)][Br](2) (2), and the 3,3'-di-n-dodecyl-1,1'(1,4-phenylenedimethylene)diimidazolium ditetrafluoroborate [p-Xyl-(dodecim)(2)][BF(4)](2) (3), differ in the alkyl chain length and in the anion properties, such as size, shape, and coordination ability. In all cases in which gelation process was observed, the obtained gels were characteri…

Supramolecular chemistrychemistry.chemical_compoundBromidePolymer chemistryElectrochemistryMoleculeOrganic chemistryGeneral Materials ScienceSpectroscopyAlkylchemistry.chemical_classificationMolecular StructureGeminalHydrogen bondChemistryImidazolesHydrogen BondingSurfaces and InterfacesSettore CHIM/06 - Chimica OrganicaCondensed Matter PhysicsResonance (chemistry)Geminal imidazolium salts Low molecular weight gelator OrganogelThermodynamicsSaltsChemical stabilityGelsOrganogels Hydrogels imidazolium salts
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Electronic structure and thermodynamic stability of double-layeredSrTiO3(001)surfaces:Ab initiosimulations

2007

Using the B3PW hybrid exchange-correlation functional within density-functional theory and employing Gaussian-type basis sets, we calculated the atomic and electronic structures and thermodynamic stability of three double-layered (DL) SrTiO3(001) surfaces: (i) SrO-terminated, (ii) TiO2-terminated, and (iii) (2×1) reconstruction of TiO2-terminated SrTiO3(001) recently suggested by Erdman et al. [Nature (London) 419, 55 (2002)]. A thermodynamic stability diagram obtained from first-principles calculations shows that regular TiO2- and SrO-terminated surfaces are the most stable. The stability regions of (2×1) DL TiO2- and DL SrO-terminated surfaces lie beyond the precipitation lines of SrO and…

Surface (mathematics)Materials sciencePrecipitation (chemistry)Covalent bondDiagramAb initioPhysical chemistryThermodynamicsChemical stabilityElectronic structureCondensed Matter PhysicsStability (probability)Electronic Optical and Magnetic MaterialsPhysical Review B
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The anion impact on the self-assembly of naphthalene diimide diimidazolium salts

2017

Naphthalene diimide diimidazolium salts differing in the anion nature were synthesized and their properties as well as their self-assembly behaviour were investigated. In particular, we took into consideration the N,N′-bis-(1-octyl-3-propylimidazolium)-naphthalene diimide cations and anions differing in size, shape and coordination abilities like [I−], [BF4−] and [NTf2−]. After determination of thermal behaviour, using differential scanning calorimetry and thermal gravimetric analysis, the electrochemical stability and redox properties were assessed using cyclic voltammetry. The self-assembly behaviour of the salts was investigated using concentration and temperature-dependent spectroscopic…

Thermogravimetric analysiselectrochemical stabilityInorganic chemistry02 engineering and technology010402 general chemistryElectrochemistryNaphthalene diimide01 natural sciencesRedoxCatalysischemistry.chemical_compoundDifferential scanning calorimetryDiimideredox propertiesMaterials Chemistryhermal gravimetric analysisIsodesmic reactiondiimidazolium saltGeneral Chemistryself assemblySettore CHIM/06 - Chimica Organica021001 nanoscience & nanotechnologyFluorescence0104 chemical scienceschemistryCyclic voltammetry0210 nano-technologyhermal gravimetric analysis;electrochemical stability;redox properties
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Properties of titanium dioxide

2021

"Properties of titanium dioxide" presents a survey of the main physicochemical properties of TiO2 upon which rely all of the applications of this material. Structures and morphologies of titanium dioxide have been taken into account, also in correlation with thermodynamic properties. Bulk and surface defectivity has been described in detail, because of its relevant consequences in terms of catalytic activity. The basic mechanisms of interaction between photons and TiO2 have been discussed on the basis of the optoelectronic features of the semiconductor. Finally, electrical, mechanical, and rheological properties of TiO2 have been presented.

Titanium dioxide Physicochemical properties Photocatalytic activity. Optoelectronic propertieschemistry.chemical_compoundMaterials scienceSemiconductorchemistrybusiness.industryTitanium dioxideNanotechnologyChemical stabilityBiocompatible materialbusiness
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Influence of bacterial physiology on processing of selenite, biogenesis of nanomaterials and their thermodynamic stability

2019

We explored how Ochrobactrum sp. MPV1 can convert up to 2.5 mM selenite within 120 h, surviving the challenge posed by high oxyanion concentrations. The data show that thiol-based biotic chemical reaction(s) occur upon bacterial exposure to low selenite concentrations, whereas enzymatic systems account for oxyanion removal when 2 mM oxyanion is exceeded. The selenite bioprocessing produces selenium nanomaterials, whose size and morphology depend on the bacterial physiology. Selenium nanoparticles were always produced by MPV1 cells, featuring an average diameter ranging between 90 and 140 nm, which we conclude constitutes the thermodynamic stability range for these nanostructures. Alternativ…

biogenic nanomaterials; selenium nanomaterials; selenite; selenium nanoparticles; selenium nanorods; Ochrobactrum; thermodynamic stability; electrosteric stabilizationPharmaceutical ScienceNanoparticlePhysiologyOxyanion02 engineering and technologySelenious AcidAnalytical ChemistryNanomaterialschemistry.chemical_compoundNanoparticleDrug Discoverychemistry.chemical_classification0303 health sciencesNanotubeselectrosteric stabilization021001 nanoscience & nanotechnologySelenium nanomaterialSelenium nanoparticleChemistry (miscellaneous)Molecular MedicineBiogenic nanomaterialNanorod0210 nano-technologybiogenic nanomaterialsselenium nanomaterialschemistry.chemical_elementOchrobactrumArticlelcsh:QD241-44103 medical and health scienceslcsh:Organic chemistryAmphiphileselenium nanoparticlesPhysical and Theoretical ChemistryParticle SizeSelenium nanorod030304 developmental biologyBiomoleculeOrganic ChemistryNanotube<i>Ochrobactrum</i>chemistry13. Climate actionNanoparticlesthermodynamic stabilityChemical stabilityseleniteselenium nanorodsSelenium
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