Search results for "chronobiology"

showing 10 items of 32 documents

Circadian and Dopaminergic Regulation of Fatty Acid Oxidation Pathway Genes in Retina and Photoreceptor Cells.

2016

The energy metabolism of the retina might comply with daily changes in energy demand and is impaired in diabetic retinopathy-one of the most common causes of blindness in Europe and the USA. The aim of this study was to investigate putative adaptation of energy metabolism in healthy and diabetic retina. Hence expression analysis of metabolic pathway genes was performed using quantitative polymerase chain reaction, semi-quantitative western blot and immunohistochemistry. Transcriptional profiling of key enzymes of energy metabolism identified transcripts of mitochondrial fatty acid β-oxidation enzymes, i.e. carnitine palmitoyltransferase-1α (Cpt-1α) and medium chain acyl-CoA dehydrogenase (A…

0301 basic medicineMalePhysiologyDopamineMice ObeseGene Expressionlcsh:MedicineBiochemistryAcyl-CoA DehydrogenaseMice0302 clinical medicineCatecholaminesEndocrinologyMedicine and Health SciencesAminesEnzyme Chemistrylcsh:ScienceBeta oxidationMice KnockoutMice Inbred C3HMultidisciplinaryOrganic CompoundsDopaminergicFatty AcidsNeurochemistryDiabetic retinopathyNeurotransmittersCircadian RhythmChemistryCircadian Oscillatorsmedicine.anatomical_structurePhysical SciencesFemaleAnatomyOxidation-Reductionmedicine.drugResearch Articlemedicine.medical_specialtyBiogenic AminesEndocrine DisordersOcular AnatomyBiologyRetinaEnzyme Regulation03 medical and health sciencesOcular SystemInternal medicinemedicineGeneticsDiabetes MellitusAnimalsPhotoreceptor CellsGene RegulationCircadian rhythmCarnitineACADMRetinaDiabetic RetinopathyCarnitine O-PalmitoyltransferaseReceptor Melatonin MT1Receptors Dopamine D4Organic Chemistrylcsh:RChemical CompoundsBiology and Life Sciencesmedicine.diseaseHormonesMice Inbred C57BLMetabolic pathwayDisease Models Animal030104 developmental biologyEndocrinologyMetabolismMicroscopy FluorescenceMetabolic DisordersEnzymologylcsh:Qsense organsEnergy MetabolismPhysiological ProcessesChronobiology030217 neurology & neurosurgeryNeurosciencePLoS ONE
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Circadian clock of Drosophila montana is adapted to high variation in summer day lengths and temperatures prevailing at high latitudes

2016

Photoperiodic regulation of the circadian rhythms in insect locomotor activity has been studied in several species, but seasonal entrainment of these rhythms is still poorly understood. We have traced the entrainment of activity rhythm of northern Drosophila montana flies in a climate chamber mimicking the photoperiods and day and night temperatures that the flies encounter in northern Finland during the summer. The experiment was started by transferring freshly emerged females into the chamber in early and late summer conditions to obtain both non-diapausing and diapausing females for the studies. The locomotor activity of the females and daily changes in the expression levels of two core …

0301 basic medicinePhysiologyTimelessPhotoperiodtimelessCircadian clockGene ExpressionZoologyBiologyDiapauseDiapause Insectphotoperiod03 medical and health sciences0302 clinical medicineCircadian Clockscircadian clockZeitgeberAnimalsDrosophila ProteinsCircadian rhythmFinlandphotoperiodismEcologyta1184TemperaturePeriod Circadian Proteinsseasonal adaptationperiod030104 developmental biologyInsect Scienceta1181Period Circadian ProteinsDrosophilalämpötilaSeasonsEntrainment (chronobiology)Locomotion030217 neurology & neurosurgeryJournal of Insect Physiology
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Salivary Inflammatory Molecules as Biomarkers of Sleep Alterations: A Scoping Review.

2021

Poor sleep quality and sleep disorders are the most common problems in people, affecting health-related quality of life. Various studies show an association between sleep disorders and altered levels of stress hormones and inflammatory cytokines measured in saliva. The main objective of this article is to provide an analysis of the current evidence related to changes in inflammatory markers in the saliva and their associations with sleep quality measurement (both objective and subjective methods) in healthy subjects and in sleep-related disorders. To that end, a scoping review was carried out, following the PRISMA criteria in the bibliographic search in several databases: PubMed, EBSCO, and…

0301 basic medicineSalivaClinical BiochemistryPopulationAlpha (ethology)InflammationReviewBioinformaticsProinflammatory cytokine03 medical and health sciences0302 clinical medicineQuality of lifecytokineMedicinesleepeducationeducation.field_of_studyChronobiologylcsh:R5-920salivabusiness.industrybiomarkersSleep in non-human animals030104 developmental biologyinflammationmedicine.symptombusinesslcsh:Medicine (General)030217 neurology & neurosurgeryDiagnostics (Basel, Switzerland)
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Rhythmic variations in reaction times and evoked potentials

1995

The present work aimed to assess the existence of a regular ultradian cyclicity underlying the variations in amplitude of the N1-P2 component of acoustic EP during a relatively long recording session and investigate its relationship with behavioral measure as RT to the same stimulus. 128 tones were presented to each subject; 128 RTs and the associated EPs to target stimuli were recorded. N1-P2 amplitude has been measured at a single trial level through Woody adaptive filter modified by Wastell. Results showed that there are ultradian rhythmic variations of N1-P2 and RT, with a periodicity from about 5 to 40 min and these variations have similar patterns in the two measures in most of the su…

Activity CyclesAdultmedicine.medical_specialtymedia_common.quotation_subjectAudiologyStimulus (physiology)RhythmmedicineReaction TimeHumansmedia_commonUltradian rhythmChronobiologyCommunicationbusiness.industryGeneral NeuroscienceElectroencephalographyGeneral MedicineElectrooculographyAmplitudeEvoked Potentials AuditorySingle trialbusinessPsychologyArousalVigilance (psychology)
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Sleep quality does not mediate the negative effects of chronodisruption on body composition and metabolic syndrome in healthcare workers in Ecuador

2020

Abstract Background and aims The objective of the present work was to determine to what extent sleep quality may mediate the association between chronodisruption (CD) and metabolic syndrome (MS), and between CD and body composition (BC). Methodology Cross-sectional study which included 300 adult health workers, 150 of whom were night shift workers and thereby exposed to CD. Diagnosis of MS was made based on Adult Treatment Panel III criteria. Sleep quality was measured using the Pittsburgh Sleep Quality Index. Body mass index (BMI), fat mass percentage, and visceral fat percentage were measured as indicators of body composition (BC). Data were analyzed using logistic, linear regression and …

AdultMaleHealth PersonnelEndocrinology Diabetes and MetabolismPhysiologyChronobiology DisordersFat massShift workPittsburgh Sleep Quality Index03 medical and health sciences0302 clinical medicineSDG 3 - Good Health and Well-beingWork Schedule ToleranceDiabetes mellitusHealth careInternal MedicinemedicineHumans030212 general & internal medicineSDG 7 - Affordable and Clean EnergyExerciseChronobiology PhenomenaMetabolic SyndromeSleep qualitybusiness.industryGeneral MedicineMiddle Agedmedicine.disease030210 environmental & occupational healthCross-Sectional StudiesBody CompositionFemaleEcuadorMetabolic syndromeEnergy IntakeSleepbusinessBody mass indexDiabetes and Metabolic Syndrome: Clinical Research and Reviews
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Temporal expectation and spectral expectation operate in distinct fashion on neuronal populations

2013

The formation of temporal expectation (i.e., the prediction of ‘when’) is of prime importance to sensory processing. It can modulate sensory processing at early processing stages probably via the entrainment of low-frequency neuronal oscillations in the brain. However, sensory predictions involve not only temporal expectation but also spectral expectation (i.e., the prediction of ‘what’). Here we investigated how temporal expectation may interrelate with spectral expectation by explicitly setting up temporal expectation and spectral expectation in a target detection task. We found that temporal expectation and spectral expectation interacted on reaction time (RT). RT was shorter when target…

AdultMaleSignal Detection PsychologicalCognitive NeuroscienceExperimental and Cognitive PsychologySensory systemElectroencephalographyta3112050105 experimental psychology03 medical and health sciencesBehavioral Neuroscience[SCCO]Cognitive science0302 clinical medicineReaction TimemedicineHumansAttention0501 psychology and cognitive sciencesta515Analysis of VarianceBrain MappingCommunicationmedicine.diagnostic_testbusiness.industrySpectrum Analysis[SCCO.NEUR]Cognitive science/Neuroscience05 social sciencesBrainSensory SystemsHealthy VolunteersOphthalmologyAcoustic StimulationEvoked Potentials AuditoryFemaleComputer Vision and Pattern RecognitionPsychologybusinessEntrainment (chronobiology)Neuroscience030217 neurology & neurosurgeryPsychoacoustics
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Circadian rhythm in the torque developed by elbow flexors during isometric contraction. Effect of sampling schedules.

1997

Time-dependent changes in elbow flexion torque have been documented according to two different sampling schedules. Seven physical education students took part in the first series of experiments, and 7 other similar subjects in the second. In both sets of experiments, the subjects performed isometric contractions: maximal and submaximal at 90 degrees in the first experiments and maximal at different angular positions in the second. After a 30-minute rest period, the torque developed was measured at 00:00, 06:00, 09:00, 12:00, 15:00, 18:00, and 21:00 h on the day of the experiment. These subjects remained in the laboratory for 24 h. In the second series of experiments, the torque developed wa…

AdultMalemedicine.medical_specialtyChronobiologyTime FactorsPhysiologyElbowBiomechanicsSampling (statistics)Isometric exerciseCircadian Rhythmmedicine.anatomical_structurePhysical medicine and rehabilitationTorquePhysiology (medical)Isometric ContractionElbow JointPhysical therapymedicineTorqueHumansFemaleCircadian rhythmElbow flexionMathematicsChronobiology international
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The effect of heavy resistance exercise on the circadian rhythm of salivary testosterone in men.

2001

Circadian rhythms of serum testosterone concentrations in men have been shown, in general, to be highest in the morning and lowest in the evening. Thus, the purpose of this investigation was to determine the effects of acute resistance exercise upon the waking circadian rhythm of salivary testosterone over 2 days (with or without resistance exercise). The subjects included ten resistance-trained men (with at least 1 year of lifting experience) with the following characteristics [mean (SD)]: age 21.6 (1.1) years; height 177.8 (9.5) cm; body mass 80.5 (11.5) kg; percent body fat 7.9 (1.7)%. A matched, randomized, crossover study design was used such that each subject was tested under both the…

AdultMalemedicine.medical_specialtyEveningWeight LiftingPhysiologyStrength trainingPhysical exercisePhysiology (medical)Internal medicinemedicineHumansOrthopedics and Sports MedicineTestosteroneCircadian rhythmExercise physiologySalivaExerciseMorningChronobiologyCross-Over Studiesbusiness.industryPublic Health Environmental and Occupational HealthGeneral MedicineCrossover studyCircadian RhythmEndocrinologybusinessEuropean journal of applied physiology
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Time of day effects on isometric and isokinetic torque developed during elbow flexion in humans

2001

The aim of this study was, firstly, to confirm or refute the existence of circadian rhythms during several velocities of concentric action of the elbow flexor muscles and, secondly, to compare the characteristics of these circadian rhythms with those obtained during isometric actions. Eight volunteer subjects participated in this study. The circadian rhythms were obtained from six test sessions (TS) carried out at different times of day over 6 days with only one TS a day. During each TS, oral temperature and the torque of the muscle action were measured. The subjects made, on an isokinetic ergometer, two maximal isokinetic concentric elbow flexions at five angular velocities (60, 120, 180, …

Adultmedicine.medical_specialtyElbow flexorPhysiologyMovementElbowIsometric exerciseConcentricBody TemperaturePhysical medicine and rehabilitationIsometric ContractionPhysiology (medical)Elbow JointmedicineHumansTorqueOrthopedics and Sports MedicineCircadian rhythmMuscle SkeletalVolunteerMathematicsChronobiologyPublic Health Environmental and Occupational HealthGeneral MedicineAnatomyCircadian Rhythmmedicine.anatomical_structureTorqueEuropean Journal of Applied Physiology
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Airborne observation of mixing across the entrainment zone during PARADE 2011

2016

This study presents the analysis of the structure and air mass characteristics of the lower atmosphere during the field campaign PARADE (PArticles and RAdicals: Diel observations of the impact of urban and biogenic Emissions) on Mount Kleiner Feldberg in southwestern Germany during late summer 2011. We analysed measurements of meteorological variables (temperature, moisture, pressure, wind speed and direction) from radio soundings and of chemical tracers (carbon dioxide, ozone) from aircraft measurements. We focus on the thermodynamic and dynamic properties that control the chemical distribution of atmospheric constituents in the boundary layer. We show that the evolution of tracer profiles…

Atmospheric ScienceOzone010504 meteorology & atmospheric sciencesMoisture010501 environmental sciencesAtmospheric sciences01 natural sciencesWind speedlcsh:QC1-999Tropospherelcsh:ChemistryBoundary layerchemistry.chemical_compoundchemistrylcsh:QD1-999TRACERddc:550Environmental scienceEntrainment (chronobiology)Diel vertical migrationlcsh:Physics0105 earth and related environmental sciencesAtmospheric Chemistry and Physics
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