Search results for "circadian"

showing 10 items of 363 documents

Insomnia symptoms combined with nocturnal hypoxia associate with cardiovascular comorbidity in the European sleep apnea cohort (ESADA)

2018

WOS: 000482433800011

AdultMalemedicine.medical_specialtyInsomniaNeurologyComorbiditySettore MED/10 - Malattie Dell'Apparato RespiratorioNocturnalHypoxemiaHypoxemia03 medical and health sciences0302 clinical medicineRisk FactorsSleep Initiation and Maintenance DisordersInternal medicinemental disordersPrevalenceInsomniaHumansMedicineHypoxiaSleep Apnea Obstructivebusiness.industrySleep Breathing Physiology and Disorders • Original ArticleSleep apneaSleep apneaMiddle AgedCardiovascular disease ; Comorbidity ; Hypoxemia ; Insomnia ; Phenotype ; Sleep apnea.Hypoxia (medical)Cardiovascular diseasemedicine.diseaseComorbidityCircadian Rhythmnervous system diseasesEuropePhenotype030228 respiratory systemOtorhinolaryngologyCardiovascular DiseasesCohortFemaleHuman medicineNeurology (clinical)medicine.symptombusiness030217 neurology & neurosurgerySleep and Breathing
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Assessment of various factors influencing esophageal pressure measurement. II. Significance of physiological factors in intraluminal manometry.

1980

In the second part of this study the effect of age, sex, body size, body weight and timing of the manometric examination (morning vs. noon) on esophageal pressure measurement was investigated in a total of 119 healthy subjects, using an electromagnetic microtransducer. Additionally intraindividual variation of pressures was studied over a period of 6 months. Of these parameters only age influenced upper esophageal sphincter (UES) pressure significantly: The mean UES pressure of younger subjects (20-49 years) was significantly higher (144.4 +/- 8.6 mmHg) compared to that of older subjects (50-80 years) where a mean pressure of 103.4 +/- 7.2 mmHg was recorded (p less than 0.0005). Intraindivi…

AdultMalemedicine.medical_specialtyManometryNormal valuesBody weightEsophagusSex FactorsReference ValuesInternal medicineDrug DiscoverymedicineHumansCircadian rhythmEsophagusGenetics (clinical)MorningPeristalsisAgedbusiness.industryBody WeightAge FactorsGeneral MedicineMiddle AgedCircadian Rhythmmedicine.anatomical_structureCardiologyEsophageal sphincterMolecular MedicineEsophageal pressureFemalePeristalsisbusinessKlinische Wochenschrift
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Frontoparietal cortex and cerebellum contribution to the update of actual and mental motor performance during the day

2016

AbstractActual and imagined movement speed increases from early morning until mid-afternoon. Here, we investigated the neural correlates of these daily changes. Fifteen subjects performed actual and imagined right finger opposition movement sequences at 8 am and 2 pm. Both actual and imagined movements were significantly faster at 2 pm than 8 am. In the morning, actual movements significantly activated the left primary somatosensory and motor areas, and bilaterally the cerebellum; in the afternoon activations were similar but reduced. Contrast analysis revealed greater activity in the cerebellum, the left primary sensorimotor cortex and parietal lobe in the morning than in the afternoon. Im…

AdultMalemedicine.medical_specialtyMovementMuscle memoryAudiology050105 experimental psychologyFunctional LateralityArticlepositron-emission-tomographyFingers03 medical and health sciencesYoung Adult0302 clinical medicineCortex (anatomy)CerebellumParietal LobemedicineHumans0501 psychology and cognitive sciencesfunctional mritimeMorningBrain MappingMultidisciplinarybusiness.industryhand movements05 social sciencesParietal lobeMotor Cortexrepresentationscircadian-rhythm periodMotor coordinationFrontal Lobemedicine.anatomical_structureFrontal lobeparietal cortexbody ownership[ SDV.NEU ] Life Sciences [q-bio]/Neurons and Cognition [q-bio.NC]Imaginationfinger movementsOrbitofrontal cortexFemaleArtificial intelligenceMotor learningbusiness030217 neurology & neurosurgeryPsychomotor Performanceimagery
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Diurnal Variation in Maximal and Submaximal Strength, Power and Neural Activation of Leg Extensors in Men: Multiple Sampling Across Two Consecutive D…

2007

This study aimed to compare day-to-day repeatability of diurnal variation in strength and power. Thirty-two men were measured at four time points (07 : 00 - 08 : 00, 12 : 00 - 13 : 00, 17 : 00 - 18 : 00, and 20 : 30 - 21 : 30 h) throughout two consecutive days (day 1 and day 2). Power during loaded squat jumps, torque and EMG during maximal (MVC) and submaximal (MVC40) voluntary isometric knee extension contractions were measured. The EMG/torque ratio during MVC and MVC40 was calculated to evaluate neuromuscular efficiency. A significant time-of-day effect with repeatable diurnal patterns was found in power. In MVC, a significant time-of-day effect was present on day 2, whereas day 1 showed…

AdultMalemedicine.medical_specialtyPhysical Therapy Sports Therapy and RehabilitationSquatElectromyographyIsometric exerciseBody TemperatureAnimal scienceIsometric ContractionmedicineHumansOrthopedics and Sports MedicineMuscle StrengthCircadian rhythmMuscle SkeletalMotor Neuronsmedicine.diagnostic_testMuscle fatigueElectromyographybusiness.industryDiurnal temperature variationRepeatabilityCircadian RhythmPower (physics)Surgerybody regionsLower ExtremityTorqueMuscle FatiguebusinessInternational Journal of Sports Medicine
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Diurnal Rhythm of the Muscular Performance of Elbow Flexors During Isometric Contractions

1996

The influence of time of day on elbow flexion torque was studied. Thirteen physical education students, 7 males and 6 females, made maximal and submaximal isometric contractions at 90 degrees of elbow flexors using a dynamometer. The torque developed was measured on each contraction. The myoelectric activity of the biceps muscle was also measured at the same time by surface electromyography (EMG) and quantified from the root mean square (RMS) activity. Torque and surface EMGs were measured at 6:00, 9:00, 12:00, 15:00, 18:00, 21:00, and 24:00 h over the same day. Oral temperature before each test session was measured on each occasion after a 30-min rest period. We observed a diurnal rhythm i…

AdultMalemedicine.medical_specialtyPhysiologyElbowPhysical exerciseElectromyographyIsometric exerciseBicepsBody TemperatureRhythmIsometric ContractionPhysiology (medical)Internal medicineElbow JointmedicineHumansCircadian rhythmMuscle SkeletalAnalysis of VariancePhysical Education and Trainingmedicine.diagnostic_testDynamometerElectromyographybusiness.industryAnatomyCircadian Rhythmmedicine.anatomical_structureTorqueCardiologyFemalebusinessChronobiology International
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Circadian rhythms in human muscular efficiency: continuous physical exercise versus continuous rest. A crossover study.

2000

This study deals with the influence of time of day on neuromuscular efficiency in competitive cyclists during continuous exercise versus continuous rest. Knee extension torque was measured in ultradistance cyclists over a 24h period (13:00 to 13:00 the next day) in the laboratory. The subjects were requested to maintain a constant speed (set at 70% of their maximal aerobic speed obtained during a preliminary test) on their own bicycles, which were equipped with cyclosimulators. Every 4h, torque developed and myoelectric activity were estimated during maximal isometric voluntary contractions of knee extensors using an isokinetic dynamometer. Mesenteric temperature was monitored by telemetry.…

AdultMalemedicine.medical_specialtyPhysiologyRestPhysical exerciseIsometric exerciseBody TemperatureRhythmPhysiology (medical)TelemetryInternal medicineIsometric ContractionmedicineHumansCircadian rhythmExercise physiologyExerciseCross-Over StudiesThermoregulationCrossover studyBicyclingCircadian RhythmMuscle FatiguePhysical therapyCardiologyPsychologyChronobiology international
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Effects of REM sleep awakenings and related wakening paradigms on the ultradian sleep cycle and the symptoms in depression.

2002

In 1975 Vogel and coworkers published their classical study where they compared selective rapid eye movement (REM) sleep deprivation by brief awakenings to a control intervention paradigm in depressed patients. The superior antidepressive impact of the first procedure was attributed to the REM pressure accumulating during the treatment period. The laborious procedure and the considerable effort necessary to evaluate the sleep profiles in real time have prevented similar experiments so far. Based on artificial neural networks we developed a software for the real time detection of REM sleep. In combination with an alarm system the algorithm allowed us to wake up subjects automatically and to …

AdultMalemedicine.medical_specialtyRapid eye movement sleepSleep REMAudiologyAntidepressive Agents TricyclicNon-rapid eye movement sleepSeverity of Illness IndexSleep Disorders Circadian RhythmSurveys and QuestionnairesmedicineHumansCircadian rhythmWakefulnessPsychiatryBiological PsychiatryUltradian rhythmSlow-wave sleepDepressionTrimipramineTrimipramineSleep in non-human animalsCircadian RhythmPsychiatry and Mental healthSleep deprivationFemalemedicine.symptomPsychologymedicine.drugJournal of psychiatric research
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Estimation of pharmacokinetic parameters of lithium from saliva and urine

1974

The salivary and urinary excretion of lithium was studied in three healthy male sub;ects after oral administration of two or three different doses. In all individuals the concentration of lithium in salivary fluid was found to be 2.2 to 3.3 times as high as the concentration in plasma. In each sub;ect the saliva:plasma concentration ratio remained constant over more than a 100 fold concentration range for at least 3 months. This ratio was not markedly affected by about tenfold changes in saliva flow rate. Thus, pharmacokinetic parameters obtained from salivary excretion data are in agreement with those obtained from plasma concentration and urinary excretion rate data, and renal clearance o…

AdultMalemedicine.medical_specialtySalivaTime FactorsSalivary ExcretionMetabolic Clearance RateAdministration OralUrineLithiumKidneyUrinary excretionPharmacokineticsOral administrationInternal medicinemedicineHumansPharmacology (medical)SalivaPharmacologyChemistrySpectrophotometry AtomicDiurnal rhythmsCircadian RhythmKineticsEndocrinologyCreatinineRegression AnalysisSalivationHalf-LifeClearanceClinical Pharmacology & Therapeutics
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Sleep-electroencephalography and the secretion of cortisol and growth hormone in normal controls.

1987

Abstract. Sleep-electroencephalography, and the nocturnal secretion of cortisol and GH were investigated simultaneously in a sample of 25 male normal controls (27.1 ± 1.3 years) in order further to examine interaction between sleep structure and concurrent endocrine activity. Slow wave sleep activity was increased during the first part of the night, whereas cortisol concentration was low and GH output reached maximal levels. The second half of the night was characterized by a relative preponderance of REM-sleep, low GH-concentration, and an increase in cortisol. However, no distinct reciprocal interaction between cortisol and GH concentration was noted. In all subjects, a pronounced GH surg…

AdultMalemedicine.medical_specialtySleep StagesSomatotropic cellHydrocortisoneEndocrinology Diabetes and MetabolismSleep REMElectroencephalographyGeneral MedicineBiologyNocturnalSleep in non-human animalsEndocrinologyEndocrinologyInternal medicineGrowth HormonemedicineHumansCircadian rhythmSleep onsetSleepHydrocortisonemedicine.drugSlow-wave sleepActa endocrinologica
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Sleepiness, sleep, and use of sleepiness countermeasures in shift-working long-haul truck drivers

2015

Driver sleepiness is a prevalent phenomenon among professional drivers working unconventional and irregular hours. For compromising occupational and traffic safety, sleepiness has become one of the major conundrums of road transportation. To further elucidate the phenomenon, an on-road study canvassing the under-explored relationship between working hours and sleepiness, sleep, and use of sleepiness countermeasures during and outside statutory rest breaks was conducted. Testing the association between the outcomes and working hours, generalized estimating equations models were fitted on a data collected from 54 long-haul truck drivers (mean 38.1 ± 10.5 years, one female) volunteering in the…

AdultMalemedicine.medical_specialtySleepinessEveningShift workPoison controlTransportationHuman Factors and ErgonomicsComputer securitycomputer.software_genreCoffeeOccupational safety and healthShift workOn-road studySleep Disorders Circadian RhythmCaffeineSurveys and QuestionnairesWork Schedule ToleranceOdds RatioHumansMedicineAttentionOccupationsSocial BehaviorSafety Risk Reliability and Qualityta515FinlandRoad transportationMorningbusiness.industryAccidents TrafficPublic Health Environmental and Occupational HealthActigraphyta3142Middle AgedConfidence intervalSleepiness countermeasureMotor VehiclesAlertnessPhysical therapyCentral Nervous System StimulantsFemaleSleepbusinesscomputerAccident Analysis & Prevention
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