Search results for "circular"

Polarization-driven spin precession of mesospheric sodium atoms

2018

We report experimental results on the first on-sky observation of atomic spin precession of mesospheric sodium driven by polarization modulation of a continuous-wave laser. The magnetic resonance was remotely detected from the ground by observing the enhancement of induced fluorescence when the driving frequency approached the precession frequency of sodium in the mesosphere, between 85 km and 100 km altitude. The experiment was performed at La Palma, and the uncertainty in the measured Larmor frequency ($\approx$260 kHz) corresponded to an error in the geomagnetic field of 0.4 mG. The results are consistent with geomagnetic field models and with the theory of light-atom interaction in the …

Towards sustainable production of minerals and chemicals through seawater brine treatment using Eutectic freeze crystallization and Electrodialysis w…

2022

European policy encourages the adoption of sustainable systems that promote the efficient use and recovery of minerals and chemicals. In this respect, desalination brines do contain a dramatic amount of valuable minerals and can be valorized through appropriate treatments rather than releasing them into the environment. This paper proposes an innovative brine recovery system for obtaining high purity chemicals through the integration of Eutectic Freeze Crystallization (EFC) and Electrodialysis with Bipolar Membrane (EDBM) technologies. Two separate laboratory-scale experimental campaigns were carried out to validate the potential integration of the two processes. Mirabilite (Na2SO4∙10H2O) h…

Life Cycle Assessment for Supporting Eco-Design: The Case Study of Sodium–Nickel Chloride Cells

2021

The European Union is moving towards a sustainable, decarbonized, and circular economy. It has identified seven key value chains in which to intervene, with the battery and vehicle value chain being one of them. Thus, actions and strategies for the sustainability of batteries need to be developed. Since Life Cycle Assessment (LCA) is a strategic tool for evaluating environmental sustainability, this paper investigates its application to two configurations of a sodium–nickel chloride cell (planar and tubular), focusing on the active material and the anode, with the purpose of identifying the configuration characterized by the lowest environmental impacts. The results, based on a “from cradle…

Development of Polyamine‐Substituted Triphenylamine Ligands with High Affinity and Selectivity for G‐Quadruplex DNA

2019

Currently, significant efforts are devoted to designing small molecules able to bind selectively to guanine quadruplexes (G4s). These noncanonical DNA structures are implicated in various important biological processes and have been identified as potential targets for drug development. Previously, a series of triphenylamine (TPA)-based compounds, including macrocyclic polyamines, that displayed high affinity towards G4 DNA were reported. Following this initial work, herein a series of second-generation compounds, in which the central TPA has been functionalised with flexible and adaptive linear polyamines, are presented with the aim of maximising the selectivity towards G4 DNA. The acid-bas…

Supramolecular Polymers: Flexible Chirality in Self-Assembled N -Annulated Perylenedicarboxamides (Small 20/2017)

2017

Trehalose effects on α-crystallin aggregates

2007

alpha-Crystallin in its native state is a large, heterogeneous, low-molecular weight (LMW) aggregate that under certain conditions may progressively became part of insoluble high-molecular weight (HMW) systems. These systems are supposed to play a relevant role in eye lens opacification and vision impairment. In this paper, we report the effects of trehalose on alpha-crystallin aggregates. The role of trehalose in alpha-crystallin stress tolerance, chaperone activity and thermal stability is studied. The results show that trehalose stabilizes the alpha-crystallin native structure, inhibits alpha-crystallin aggregation, and disaggregates preformed LMW systems not affecting its chaperone acti…

The large-scale magnetic field of the eccentric pre-main-sequence binary system V1878 Ori

2020

We report time-resolved, high-resolution optical spectropolarimetric observations of the young double-lined spectroscopic binary V1878 Ori. Our observations were collected with the ESPaDOnS spectropolarimeter at the Canada-France-Hawaii Telescope through the BinaMIcS large programme. V1878 Ori A and B are partially convective intermediate mass weak-line T Tauri stars on an eccentric and asynchronous orbit. We also acquired X-ray observations at periastron and outside periastron. Using the least-squares deconvolution technique (LSD) to combine information from many spectral lines, we clearly detected circular polarization signals in both components throughout the orbit. We refined the orbita…

Sphingomyelin induces structural alteration in canine parvovirus capsid.

2007

One of the essential steps in canine parvovirus (CPV) infection, the release from endosomal vesicles, is dominated by interactions between the virus capsid and the endosomal membranes. In this study, the effect of sphingomyelin and phosphatidyl serine on canine parvovirus capsid and on the phospholipase A(2) (PLA(2)) activity of CPV VP1 unique N-terminus was analyzed. Accordingly, a significant (P< or =0.05) shift of tryptophan fluorescence emission peak was detected at pH 5.5 in the presence of sphingomyelin, whereas at pH 7.4 a similar but minor shift was observed. This effect may relate to the exposure of VP1 N-terminus in acidic pH as well as to interactions between sphingomyelin and CP…

Extracellular Vesicles-ceRNAs as Ovarian Cancer Biomarkers: Looking into circRNA-miRNA-mRNA Code

2022

Simple Summary Patients with ovarian cancer have a very poor chance of long-term survival, usually due to advanced disease at the time of diagnosis. Emerging evidence suggests that extracellular vesicles contain noncoding RNAs such as microRNAs, piwiRNAs, circular RNAs, and long noncoding RNAs, with regulatory effects on ovarian cancer. In this review, we focus on ovarian cancer-associated circular RNA shuttled by extracellular vesicles as mediators of cancer progression and novel biomarkers in liquid biopsy. We propose a circular-RNA-microRNA-mRNA code that can reveal the regulatory network created by extracellular vesicles, noncoding RNAs, and mRNAs in ovarian cancer. Future research in t…

Innovative Non-Thermal Technologies for Recovery and Valorization of Value-Added Products from Crustacean Processing By-Products—An Opportunity for a…

2021

The crustacean processing industry has experienced significant growth over recent decades resulting in the production of a great number of by-products. Crustacean by-products contain several valuable components such as proteins, lipids, and carotenoids, especially astaxanthin and chitin. When isolated, these valuable compounds are characterized by bioactivities such as anti-microbial, antioxidant, and anti-cancer ones, and that could be used as nutraceutical ingredients or additives in the food, pharmaceutical, and cosmetic industries. Different innovative non-thermal technologies have appeared as promising, safe, and efficient tools to recover these valuable compounds. This review aims at …