Search results for "circulatory and respiratory physiology"

showing 10 items of 329 documents

Quantitative structure-retention and retention-activity relationships of beta-blocking agents by micellar liquid chromatography.

2001

Abstract Sixteen β-blocking agents (acebutolol, alprenolol, atenolol, bisoprolol, carteolol, celiprolol, esmolol, labetalol, metoprolol, nadolol, oxprenolol, pindolol, practolol, propranolol, sotalol and timolol) showing a large range of hydrophobicity (octanol–water partition coefficients, log P between −0.026 and 2.81) were subjected to micellar liquid chromatography with sodium dodecyl sulfate as micelle forming agent, and n-propanol as organic modifier. The correlation between log P and the retention factor extrapolated to a mobile phase free of micelles and organic modifier was investigated. The use of an interpolated retention factor or the retention factor for specific individual exp…

ChromatographyChemistryOrganic ChemistryAdrenergic beta-AntagonistsQuantitative Structure-Activity RelationshipGeneral MedicineBiochemistryMicelleAcebutololMicellar electrokinetic chromatographyAnalytical ChemistryPartition coefficientchemistry.chemical_compoundMicellar liquid chromatographyOxprenololmedicineAlprenololSodium dodecyl sulfateMicellescirculatory and respiratory physiologymedicine.drugChromatography LiquidJournal of chromatography. A
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Selection of blood pressure signal for baroreflex analysis

2020

This study aims to evaluate the strength of the causal coupling among systolic, mean and diastolic blood pressure (SBP, MBP and DBP) with heart period (RR interval) (evaluating cardiac chronotropic baroreflex arm) and peripheral vascular resistance (PVR) (evaluating vascular resistance baroreflex arm) in frequency domain using partial spectral decomposition method. We recorded beat-to-beat RR, SBP, MBP and DBP and PVR values in 39 volunteers during supine rest and head-up tilt. Our results showed that during supine rest the most dominant causal coupling was from DBP to RR in both low and high frequency bands and significantly decreased during orthostasis. The strength of spectral couplings …

Chronotropicmedicine.medical_specialtySupine positionbusiness.industryRR intervalLow frequency bandBaroreflexBlood pressuremedicine.anatomical_structureInternal medicineSettore ING-INF/06 - Bioingegneria Elettronica E InformaticaCardiologyVascular resistanceBlood pressureMedicinecardiovascular diseasesbusinesscirculatory and respiratory physiology
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Chiral separation of oxprenolol by affinity electrokinetic chromatography-partial filling technique using human serum albumin as chiral selector

2005

The intrinsic characteristics of capillary electrophoresis have made this technique a powerful tool in the chiral separation field. The present paper deals with the enantiomeric separation of oxprenolol enantiomers by affinity electrokinetic chromatography-partial filling technique using human serum albumin (HSA) as chiral selector. Several experimental conditions and variables affecting the separation such as pH, HSA concentration and plug length, background electrolyte concentration, temperature and voltage were studied. Baseline separation of oxprenolol enantiomers was obtained in less than 8 min under the following selected conditions: electrophoretic buffer composed of 50 mM Tris-(hydr…

Clinical BiochemistrySerum albuminAnalytical chemistryPharmaceutical ScienceChromatography AffinityAnalytical ChemistryElectrokinetic phenomenaCapillary electrophoresisAffinity chromatographyDrug DiscoverymedicineHumansSerum AlbuminSpectroscopyChromatographybiologyChemistryOxprenololStereoisomerismHuman serum albuminElectrophoresisOxprenololbiology.proteinEnantiomercirculatory and respiratory physiologymedicine.drugJournal of Pharmaceutical and Biomedical Analysis
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Cardiopulmonary Exercise Testing in Patients with Chronic Heart Failure: Prognostic Comparison from Peak VO2 and VE/VCO2 Slope

2010

Background: Cardiopulmonary exercise testing with ventilatory expired gas analysis (CPET) has proven to be a valuable tool for assessing patients with chronic heart failure (CHF). The maximal oxygen uptake (peak V02) is used in risk stratification of patients with CHF. The minute ventilation-carbon dioxide production relationship (VE/VCO2 slope) has recently demonstrated prognostic significance in patients with CHF. Methods: Between January 2006 and December 2007 we performed CPET in 184 pts (146 M, 38 F, mean age 59.8 ± 12.9 years), with stable CHF (96 coronary artery disease, 88 dilated cardiomyopathy), in NYHA functional class II (n.107) - III (n.77), with left ventricular ejection frac…

Congestive heart failuremedicine.medical_specialtygas exchangeArticleCoronary artery diseaseInternal medicineMedicineEjection fractionReceiver operating characteristicbusiness.industryventilationVO2 maxDilated cardiomyopathyCARDIOPULMONARY CHRONIC HEART FAILUREmedicine.diseaseexercise capacityLog-rank testprognosis.Heart failureBreathingCardiologyPhysical therapyCardiology and Cardiovascular Medicinebusinesshuman activitiescirculatory and respiratory physiologyThe Open Cardiovascular Medicine Journal
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Comparison of DNase, DNA-polymerase and RNA-polymerase activities present in the DNA-bindung proteins of normal human dermis, epidermis, horny layer …

1978

DNA-binding proteins (DBP) of normal human dermis, epidermis, horny layer and psoriatic scales represent a tissue-specific group of mostly nuclear nonhistone proteins. To analyse their function, the different DBP fractions were examined concerning the presence of DNase, DNA-polymerase and RNA-polymerase activities. DBP of normal epidermis and horny layer contain four different DNases. One DNase of both DBP fractions is active only at pH 5.0. Three DNases of epidermal DBP are active at a pH-range from 5.0--8.5, while the corresponding DNases of horny layer-DBP are most active at pH 7.4. Probably these DNases have changed their pH-optimum during keratinisation. DBP of psoriatic scales include…

DNA polymeraseDNA-Directed DNA PolymeraseDermatologychemistry.chemical_compoundNon-histone proteinDermisRNA polymerasemedicineHumansPsoriasisSkinchemistry.chemical_classificationThymidine monophosphateDeoxyribonucleasesEpidermis (botany)biologyIsoelectric focusingProteinsDNA-Directed RNA PolymerasesGeneral MedicineElectrophoresis DiscMolecular biologyEnzyme Activationmedicine.anatomical_structureEnzymechemistrybiology.proteinEpidermisIsoelectric FocusingProtein Bindingcirculatory and respiratory physiologyArchives of Dermatological Research
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Induction of digoxin-like material production, and the digoxin binding in the unicellular organism Tetrahymena by digitoxin.

1998

Thin layer chromatographic, and laser-confocal microscopic analyses with a monoclonal antibody to digoxin also displaying high affinity to digoxigenin, were used to determine the presence and localization of cardioactive glycosides. Tetrahymena pyriformis was found to possess digitoxigenin-like material, but digoxin, digitoxin, digoxigenin, gitoxin and lanatoside C were not detected. Digitoxin treatment elicited the appearance of a digoxin-like material in the progeny generations. Digoxin was taken up by untreated Tetrahymena, especially strongly 24 h after digitoxin treatment. While the cardenolide was localized in vesicles of the cell body in untreated Tetrahymena, the engulfed digoxin ap…

DigoxinDigoxinDigitoxinBiologychemistry.chemical_compoundDigitoxinpolycyclic compoundsmedicineCardenolideDigoxigeninAnimalscardiovascular diseasesChromatography High Pressure Liquidchemistry.chemical_classificationBinding SitesMicroscopy ConfocalTetrahymena pyriformisdigestive oral and skin physiologyCell MembraneLanatoside CTetrahymenaDigitalis GlycosidesBiological TransportCell BiologyGeneral Medicinebiology.organism_classificationImmunohistochemistrycarbohydrates (lipids)EnzymechemistryBiochemistryTetrahymena pyriformiscirculatory and respiratory physiologymedicine.drugCell biology international
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"Table 3" of "Measurement of the production cross section for W-bosons in association with jets in pp collisions at sqrt(s) = 7 TeV with the ATLAS de…

2011

The measured cross section ratio for W+jets in the electron channel as a function of corrected jet multiplicity.

Electron productionAstrophysics::High Energy Astrophysical PhenomenaIntegrated Cross Section7000.0Jet Productionrespiratory systemCross Sectionequipment and suppliesP P --> W- JETS XSIGcomplex mixturesP P --> W+ JETS XInclusive2611940326119403Proton-Proton ScatteringHigh Energy Physics::Experimenthuman activitiesW Productioncirculatory and respiratory physiologyComputer Science::Information Theory
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"Table 2" of "Inclusive production of the omega and eta mesons in Z decays, and the muonic branching ratio of the omega."

2002

Production rate and differential cross sections for the ETA.

Electron productionE+ E- --> HADRONSIntegrated Cross SectionDeep Inelastic Scattering91.2respiratory systemCross SectionE+ E- --> ETA XDSIG/DXSIGInclusiveSingle Differential Cross SectionE+ E- Scatteringcardiovascular systemExclusiveHigh Energy Physics::ExperimentR measurementNuclear Experimentcirculatory and respiratory physiology
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"Table 9" of "Measurement of the cross section for W-boson production in association with jets in ppbar collisions at s**(1/2) = 1.96-TeV"

2008

Total cross sections for W production in association with 4 or more jets.

Electron productionIntegrated Cross SectionJet Productionrespiratory systemCross Sectionequipment and suppliesSIGcomplex mixturesInclusivePBAR P --> W+ .GE.4JET XPBAR P --> W- .GE.4JET X1960.0human activitiesW Productioncirculatory and respiratory physiology
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"Table 6" of "Measurement of the cross section for W-boson production in association with jets in ppbar collisions at s**(1/2) = 1.96-TeV"

2008

Total cross sections for W production in association with 1 or more jets.

Electron productionIntegrated Cross SectionJet Productionrespiratory systemCross Sectionequipment and suppliesSIGcomplex mixturesInclusivePBAR P --> W- .GE.1JET X1960.0human activitiesPBAR P --> W+ .GE.1JET XW Productioncirculatory and respiratory physiology
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