Search results for "clearance rate"

showing 10 items of 40 documents

An energy budget for the subtidal bivalve Modiolus barbatus (Mollusca) at different temperatures

2011

Clearance rates, respiration rates and food absorption efficiencies of the commercially interesting subtidal bivalve Modiolus barbatus were measured at different temperatures under laboratory conditions and scope for growth calculated. Clearance rates were highest at temperatures from 20 °C to 28 °C, whereas respiration rate was maximal at 9 °C and minimal at 26 °C. Highest mean values of absorbed energy occurred at 20 °C and 26 °C. Scope for growth trend had negative values at 9 °C, 15 °C and 28 °C and positive values at temperatures 20 °C and 26 °C. The profitable thermal window for M. barbatus to have energy sufficient for growth and reproduction corresponded to <5 months per year. Seawa…

Settore BIO/07 - Ecologia0106 biological sciencesModiolus barbatusAquatic ScienceOceanography010603 evolutionary biology01 natural sciencesModiolus barbatus; Mediterranean; scope for growth; temperature; respiration; clearance; physiologyOxygen ConsumptionAnimal scienceStress PhysiologicalRespirationAnimalsSeawater14. Life underwaterMolluscabiologyEcology010604 marine biology & hydrobiologyTemperatureGeneral MedicineBivalviabiology.organism_classificationEnergy budgetPollutionMytilidaeSeawaterEnergy MetabolismModiolus barbatus Mediterranean scope for growth temperature respiration clearance physiologyRespiration rateClearance rateMarine Environmental Research
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Effect of the presence of the shore crab, Carcinus maenas, on the burrowing behaviour and clearance rate of the common cockle, Cerastoderma edule

2011

Bivalves demonstrate various morphological and behavioural adaptations to reduce the risk of being attacked by predators. This paper examines how the presence of the crab Carcinus maenas (L.), a natural predator of the cockle Cerastoderma edule (L.), affects its burrowing depth and clearance or feeding rate. Cockles were placed in experimental tanks and treated with three levels of predatory disturbance: (1) unfed crab loose inside the tank, (2) unfed crab inside a cage suspended in the water column and (3) no crab present. Cockles’ burrowing depth was measured in two sediment types: mud and sand. Cockles burrowed more deeply in treatments with no crabs. Burrowing depth in sand was signific…

Settore BIO/07 - EcologiaCerastoderma eduleEcologyDecapodaCarcinus maenas clearance rate Cerastoderma eduleAquatic ScienceBiologybiology.organism_classificationBivalviaCrustaceanFisheryCarcinus maenasCockleClearance rateMolluscaEcology Evolution Behavior and Systematics
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Effect of salinity and temperature on feeding physiology and scope for growth of an invasive species (Brachidontes pharaonis - MOLLUSCA: BIVALVIA) wi…

2008

Abstract The Indo-Pacific mytilid Brachidontes pharaonis (Bivalvia, Fischer 1870) offers an excellent model for the study of “Lessepsian migration” and the successive colonization at new Mediterranean locations. This species in out competing indigenous bivalves is particularly well adapted to Mediterranean conditions and this is likely due to biological characteristics and physio-ecological plasticity. In the present paper, we report on clearance rate (CR), respiration rate (RR) and Scope for Growth (SFG) of B. pharaonis collected from a Western Sicilian pond (Southern Tyrrhenian, MED). Physiological variables were determined in response to a range of temperatures from 11 ° to 20 °C and a b…

Settore BIO/07 - EcologiaLessepsian migrationEcologyAquatic ScienceBiologybiology.organism_classificationBivalviaBiological invasions Brachidontes pharaonis Clearance rate Lesseptian migration Mediterranean Scope for growthSalinityMediterranean seaBrachidontes pharaonisRespiration rateClearance rateMolluscaEcology Evolution Behavior and SystematicsJournal of Experimental Marine Biology and Ecology
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Combined effects of thermal conditions and food availability on thermal tolerance of the marine bivalve, Perna viridis

2018

Abstract Organisms can mitigate the effects of long term variation in environmental conditions through acclimation, which involves changes in various physiological responses. To elucidate the possible effects of temperature and food concentrations on acclimation capacity, physiological responses of the mussel, Perna viridis, were measured after individuals were held for six weeks under varying temperatures and food availability. Warm-acclimated mussels experiencing higher food levels had significantly greater upper thermal limits than those maintained on lower food levels. In contrast, the upper thermal limits of cold-acclimated mussels were not affected by food levels. For warm-acclimated …

Thermotolerance0106 biological sciencesPernaanimal structuresPhysiologyDynamic energy budget010603 evolutionary biology01 natural sciencesBiochemistryAcclimatizationAnimal scienceAquacultureAnimalsbiologybusiness.industryFood availability010604 marine biology & hydrobiologyfungiMusselbiology.organism_classificationPhysiological responsesDietEnvironmental scienceEnergy MetabolismGeneral Agricultural and Biological SciencesbusinessClearance rateDevelopmental BiologyPerna viridisJournal of Thermal Biology
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PET Studies of d-Methamphetamine Pharmacokinetics in Primates: Comparison with l-Methamphetamine and (—)-Cocaine

2007

The methamphetamine molecule has a chiral center and exists as 2 enantiomers, d-methamphetamine (the more active enantiomer) and l-methamphetamine (the less active enantiomer). d-Methamphetamine is associated with more intense stimulant effects and higher abuse liability. The objective of this study was to measure the pharmacokinetics of d-methamphetamine for comparison with both l-methamphetamine and (-)-cocaine in the baboon brain and peripheral organs and to assess the saturability and pharmacologic specificity of binding.d- and l-methamphetamine and (-)-cocaine were labeled with (11)C via alkylation of the norprecursors with (11)C-methyl iodide using literature methods. Six different ba…

biologyMethylphenidateChemistryMetabolic Clearance Ratemedicine.medical_treatmentTetrabenazineBrainStriatumPharmacologyMethamphetamineArticleMethamphetamineStimulantPharmacokineticsCocainebiology.animalPositron-Emission TomographymedicineDistribution (pharmacology)AnimalsRadiology Nuclear Medicine and imagingTissue Distributionmedicine.drugBaboonPapio
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Special Considerations for Antihypertensive Agents in Dialysis Patients

2010

Hypertension is present in most patients with end-stage renal disease and likely contributes to the premature cardiovascular disease in dialysis patients. Previous practice guidelines have recommended that, in patients on chronic dialysis, blood pressure (BP) should be reduced below 130/80 mm Hg. This is based on opinions but not strong evidence, since no concrete information exists about which BP values should be the parameter to follow and which should be the target BP values. The majority of the antihypertensive agents can be used in this population, but the pharmacokinetics altered by the impaired kidney function and dialyzability influence the appropriate dosage as well as the time and…

medicine.medical_specialtyCardiotonic AgentsHypertension RenalCombination therapyMetabolic Clearance Ratemedicine.drug_classVasodilator Agentsmedicine.medical_treatmentAdrenergic beta-AntagonistsPopulationAngiotensin-Converting Enzyme InhibitorsCardiotonic AgentsRenal DialysisInternal medicinemedicineHumansDrug InteractionsDiureticseducationAntihypertensive drugAntihypertensive AgentsDialysisRandomized Controlled Trials as Topiceducation.field_of_studybusiness.industryHematologyGeneral MedicineCalcium Channel Blockersmedicine.diseaseEndocrinologyBlood pressureCardiovascular DiseasesNephrologyPractice Guidelines as TopicPolypharmacyKidney Failure ChronicDrug Therapy CombinationHemodialysisbusinessAngiotensin II Type 1 Receptor BlockersKidney diseaseBlood Purification
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Prediction of dilutional acidosis based on the revised classical dilution concept for bicarbonate

2004

Due to the controversy surrounding the term dilutional acidosis, the classical dilution concept for bicarbonate has been rigorously revised for the prediction of pH, actual bicarbonate concentration, and base excess. In the algorithms derived for buffer solutions, blood, and whole body (1-, 2-, and 3-fluid compartment), only bicarbonate is considered. On dilution at constant Pco2, the final concentration of bicarbonate is the sum in terms of pH, due to the following processes: dilution, formation from chemical reaction with the nonbicarbonate buffers phosphate, hemoglobin, and plasma proteins, and transfer from erythrocytes and interstitial fluid to plasma. At constant Pco2, the level of c…

medicine.medical_specialtyMetabolic Clearance RatePhysiologyBicarbonateVolume replacementIndicator Dilution TechniquesModels Biologicalchemistry.chemical_compoundPhysiology (medical)Volume expansionBicarbonate buffering systemmedicineAnimalsHumansComputer SimulationTissue DistributionDiagnosis Computer-AssistedAcidosisChemistryAcute normovolemic hemodilutionMetabolic disorderHydrogen-Ion ConcentrationPrognosismedicine.diseaseSurgeryDilutionBicarbonatesModels ChemicalAnesthesiamedicine.symptomAcidosisAlgorithmsJournal of Applied Physiology
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The impact of occult renal failure on the cardiovascular risk stratification in an elderly population: the PREV-ICTUS study.

2008

To analyze the impact of occult renal failure (ORF) in the individual risk stratification and on the blood pressures (BP) and low-density lipoprotein (LDL) goals in an aged population, according to the ESH/ESC Hypertension Guidelines.A cross-sectional, population-based study on individuals aged 60 years or more carried out in Primary Care Centers of Spain. Kidney function was estimated from calculated creatinine clearance (eGFR), Cockroft and Gault formula. Ten-year cardiovascular risk was estimated through the ESH/ESC table including or not including the eGFR. Estimates of the modification in BP and LDL-cholesterol (cLDL) goals were calculated.In 6419 subjects, 4242 subjects (66%) had norm…

medicine.medical_specialtyMetabolic Clearance RatePopulationRenal functionBlood PressureIndividual riskNormal renal functionPopulation GroupsRisk FactorsInternal medicineElderly populationInternal MedicinemedicineHumansRenal InsufficiencyeducationAgededucation.field_of_studybusiness.industryGeneral MedicineCholesterol LDLMiddle AgedOccultEndocrinologyCross-Sectional StudiesLogistic ModelsCardiovascular DiseasesSpainCreatinineRisk stratificationHypertensionPractice Guidelines as TopicCardiology and Cardiovascular MedicinebusinessLipoproteinGlomerular Filtration RateBlood pressure
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Comprehensive pharmacokinetic model of insulin Glargine and other insulin formulations.

2005

In this paper, a comprehensive pharmacokinetic model for different insulin formulations including insulin Glargine is developed based on the model proposed by Trajanoski et al. (1993). Current models show limitations for insulin Glargine due to the appearance of an uncharacteristic peak in the concentration-time evolution of plasma insulin that does not coincide with real experimental data. This important limitation has been solved in this paper by introducing a new virtual insulin state called the bound state, in addition to the dimeric and hexameric ones. Trying to describe the retarded action of insulin Glargine, the modeling idea behind this approach is that immediately after the subcut…

medicine.medical_specialtyMetabolic Clearance Ratemedicine.medical_treatmentBiomedical EngineeringInsulin GlargineModels BiologicalInsulin Infusion SystemsPharmacokineticsInternal medicinemedicineApplied mathematicsHumansInsulinComputer SimulationSpatial diffusionMathematicsInsulin glargineInsulinDrug Therapy Computer-AssistedInsulin Long-ActingExogenous insulinEndocrinologyLiverPatient behaviorPlasma insulinmedicine.drugIEEE transactions on bio-medical engineering
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Gadolinium accumulation after contrast-enhanced magnetic resonance imaging: Which implications in patients with Crohn's disease?

2017

Crohn's disease (CD) is a chronic inflammatory condition of the bowel, characterized by an alternation of remission and relapse phases, leading to a progressive intestinal damage with loss of function. Magnetic resonance enterography has been widely used in the past for the evaluation of fistulizing disease, but its use increased over time, being considered helpful in different moments of disease course. Intravenous injection of Gadolinium-based contrast agents has been demonstrated to be crucial to assess mucosal inflammation, transmural involvement, and extraintestinal disease. Recently, Gadolinium accumulation in human tissues has been increasingly reported, although clinical implication…

medicine.medical_specialtyPathologyMetabolic Clearance RateGadoliniumchemistry.chemical_elementContrast MediaGadoliniumDiseaseGastroenterology030218 nuclear medicine & medical imaging03 medical and health sciencesGadolinium storage condition0302 clinical medicineCrohn DiseaseInternal medicineMedicineHumansIn patientTissue DistributionContrast-enhanced Magnetic Resonance ImagingCrohn's diseasemedicine.diagnostic_testHepatologybusiness.industryCrohn's disease; Gadolinium; Gadolinium storage condition; Magnetic resonance imaging; Hepatology; GastroenterologyGastroenterologyMagnetic resonance imagingHepatologymedicine.diseaseMagnetic resonance enterographyMagnetic Resonance ImagingCrohn's diseasechemistryDisease Progression030211 gastroenterology & hepatologybusinessDigestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver
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