Search results for "clinical decision making"

showing 4 items of 14 documents

Rare Cancers Europe (RCE) methodological recommendations for clinical studies in rare cancers: A European consensus position paper

2015

While they account for one-fifth of new cancer cases, rare cancers are difficult to study. A higher than average degree of uncertainty should be accommodated for clinical as well as for population-based decision making. Rules of rational decision making in conditions of uncertainty should be rigorously followed and would need widely informative clinical trials. In principle, any piece of new evidence would need to be exploited in rare cancers. Methodologies to explicitly weigh and combine all the available evidence should be refined, and the Bayesian logic can be instrumental to this end. Likewise, Bayesian-design trials may help optimize the low number of patients liable to be enrolled in …

Research designPathologyData baseResearch methodologyElectronic medical recordDiseaseReviewProceduresTreatment responseClinical trials; Rare cancers; Research methodology; Clinical Studies as Topic; Humans; Neoplasms; Rare Diseases; Research Design; Hematology; OncologyClinical trialsNeoplasmsReimbursementPriority journaleducation.field_of_studyClinical Studies as TopicClinical studies as topicHematologyRare diseasesEuropeOncologyResearch designResearch DesignClinical decision makingHumanmedicine.medical_specialtyPractice guidelineCase findingPopulationHealth care qualityReviewsCancer researchClinical studyRare DiseasesSDG 3 - Good Health and Well-beingConceptual frameworkmedicineHumansRare cancersTumor markerIntensive care medicineeducationAntineoplastic activityFlexibility (engineering)Surrogate endpointbusiness.industryMethodologyRare cancerStudy designCancer survivalReimbursementClinical trialClinical trials; Rare cancers; Research methodology; Hematology; OncologyPatient informationClinical effectivenessPosition paperNeoplasmbusinessRare disease
researchProduct

Thyroid surgery and radioiodine ablation—the surgeon's role

2012

Total thyroidectomy and subsequent radioiodine ablation improve the outcome of patients with thyroid tumours measuring >1 cm. Best practice guidelines should serve as a basis for clinical decision making in stage I thyroid cancer; however, Haymart et al. report that soft factors, unrelated to clinical presentation, affect the rate of radioiodine ablation.

Total thyroidectomymedicine.medical_specialtybusiness.industryEndocrinology Diabetes and Metabolismmedicine.medical_treatmentThyroidRadioiodine ablationThyroidectomyThyroid tumoursmedicine.diseaseSurgeryEndocrinologymedicine.anatomical_structureClinical decision makingmedicinebusinessThyroid cancerNature Reviews Endocrinology
researchProduct

Author's reply: Comment on “Why are Cochrane hepato-biliary reviews undervalued by physicians as an aid for clinical decision making?”

2010

medicine.medical_specialtyHepatologyClinical decision makingbusiness.industryFamily medicineGastroenterologymedicineAlternative medicinebusinessDigestive and Liver Disease
researchProduct

Why are Cochrane hepato-biliary reviews undervalued by physicians as an aid for clinical decision-making?

2009

Abstract Background Cochrane systematic reviews are of higher quality than reviews published in scientific journals, yet are used less than other sources for clinical decision-making. Aim To assess whether the characteristics of the Cochrane systematic reviews can account for their scant use by physicians. Materials and methods We analysed the 87 Cochrane hepato-biliary reviews dealing with therapeutic topics posted in the Cochrane Database of Systematic Reviews through December 2008, which we classified according to four characteristics: empty reviews; outdated reviews; content of reviews; implications for practice. Results Six empty reviews found no eligible randomised trials and six foun…

medicine.medical_specialtyPediatricsEvidence-Based MedicineHepatologybusiness.industryBiliary Tract DiseasesLiver DiseaseseducationGastroenterologyAlternative medicinePsychological interventionReview Literature as TopicSystematic reviewClinical decision makingFamily medicinemedicineHumansbusinessDigestive and Liver Disease
researchProduct