Search results for "coating"

showing 10 items of 2834 documents

Asymmetric synthesis of 3,3′-pyrrolidinyl-dispirooxindoles via a one-pot organocatalytic Mannich/deprotection/aza-Michael sequence

2016

Chemical communications 52, 2249-2252 (2016). doi:10.1039/C5CC10057G

3'-pyrrolidinyl-spirooxindole3010405 organic chemistryChemistryMannich/deprotection/aza-Michael sequenceMetals and AlloysEnantioselective synthesisSequence (biology)General Chemistrychemistry010402 general chemistry54001 natural sciencesCombinatorial chemistryCatalysis0104 chemical sciencesSurfaces Coatings and FilmsElectronic Optical and Magnetic MaterialsCatalysisStereocenterddc:540Materials ChemistryCeramics and CompositesStereoselectivityta116
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Gold nanostar–polymer hybrids for siRNA delivery: Polymer design towards colloidal stability and in vitro studies on breast cancer cells

2017

To overcome the low bioavailability of siRNA (small interfering RNA) and to improve their transfection efficiency, the use of non-viral delivery carriers is today a feasible approach to transform the discovery of these incredibly potent and versatile drugs into clinical practice. Polymer-modified gold nanoconstructs (AuNCs) are currently viewed as efficient and safe intracellular delivery carriers for siRNA, as they have the possibility to conjugate the ability to stably entrap and deliver siRNAs inside cells with the advantages of gold nanoparticles, which can act as theranostic agents and radiotherapy enhancers through laser-induced hyperthermia. In this study, AuNCs were prepared by coat…

3003siRNA deliverySmall interfering RNAPolymersMetal NanoparticlesPharmaceutical ScienceGold Colloid02 engineering and technologyPolyethylene Glycol01 natural sciencesPolyethylene GlycolsGold Colloidchemistry.chemical_compoundDrug Delivery SystemsMCF-7 CellDrug StabilityCoatingRNA Small InterferingPolymerDrug Carrierchemistry.chemical_classificationDrug CarriersTumorLipoic acidGold nanostarPolymer021001 nanoscience & nanotechnologyColloidal goldMCF-7 Cells0210 nano-technologyDrug carrierHydrophobic and Hydrophilic InteractionsBreast NeoplasmHumanBiological AvailabilityReproducibility of ResultBreast NeoplasmsNanotechnologyPolyethylene glycolengineering.materialSmall InterferingTransfection010402 general chemistryCell LineHydrophobic and Hydrophilic InteractionMetal NanoparticleCell Line TumorAmphiphileHumansGene SilencingParticle SizeGold nanostarsReproducibility of ResultsGold nanostars; Lipoic acid; MCF-7; PEG; PHEA; siRNA delivery; Biological Availability; Breast Neoplasms; Cell Line; Tumor; Drug Carriers; Drug Delivery Systems; Drug Stability; Gene Silencing; Gold; Gold Colloid; Humans; Hydrophobic and Hydrophilic Interactions; MCF-7 Cells; Metal Nanoparticles; Particle Size; Polyethylene Glycols; Polymers; RNA; Small Interfering; Reproducibility of Results; Transfection; 3003PHEAPEG0104 chemical scienceschemistrySettore CHIM/09 - Farmaceutico Tecnologico ApplicativoengineeringRNAGoldMCF-7Drug Delivery SystemInternational Journal of Pharmaceutics
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Preparation of polycrystalline TiO2 photocatalysts impregnated with various transition metal ions : characterization and photocatalytic activity for …

2002

A set of polycrystalline TiO2 photocatalysts loaded with various ions of transition metals (Co, Cr, Cu, Fe, Mo, V, and W) were prepared by using the wet impregnation method. The samples were characterized by using some bulk and surface techniques, namely X-ray diffraction, BET specific surface area determination, scanning electron microscopy, point of zero charge determination, and femtosecond pump-probe diffuse reflectance spectroscopy (PP-DRS). The samples were employed as catalysts for 4-nitrophenol photodegradation in aqueous suspension, used as a probe reaction. The characterization results have confirmed the difficulty to find a straightforward correlation between photoactivity and si…

431Materials scienceDiffuse reflectance infrared fourier transformScanning electron microscopeAnalytical chemistry436Surfaces Coatings and FilmsTransition metalSpecific surface areaMaterials ChemistryPoint of zero chargeCrystalliteDiffuse reflectionPhysical and Theoretical ChemistryPhotodegradationJournal of physical chemistry. B
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Characterization of the Solid State Properties of Anodic Oxides on Magnetron Sputtered Ta, Nb and Ta-Nb Alloys

2012

Tantalum oxide, niobium oxide and Ta-Nb containing mixed oxides were grown by anodizing sputter-deposited Ta, Nb and Ta-Nb alloys of different compositions. A photoelectrochemical investigation was performed in order to estimate the band gap and the flat band potential of the oxides as a function of their composition. The band gap of the investigated Ta-Nb containing mixed oxides changed monotonically between those estimated for Ta2O5 (4.1 eV) and Nb2O5 (3.4 eV) and in agreement with a proposed correlation between the Band gap of an oxide and the difference of electronegativity of the oxide constituents. From the differential capacitance curves recorded in a wide range of electrode potentia…

431Materials scienceRenewable Energy Sustainability and the EnvironmentSolid-stateCondensed Matter PhysicsSolid State Properties Anodic Oxides Ta-Nb AlloysSurfaces Coatings and FilmsElectronic Optical and Magnetic MaterialsCharacterization (materials science)AnodeSettore ING-IND/23 - Chimica Fisica ApplicataChemical engineeringCavity magnetronMaterials ChemistryElectrochemistry
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Rational Design of Thermoresponsive Microgel Templates with Polydopamine Surface Coating for Microtissue Applications.

2021

Functional microgels provide a versatile basis for synthetic in vitro platforms as alternatives to animal experiments. The tuning of the physical, chemical, and biological properties of synthetic microgels can be achieved by blending suitable polymers and formulating them such to reflect the heterogenous and complex nature of biological tissues. Based on this premise, this paper introduces the development of volume-switchable core-shell microgels as 3D templates to enable cell growth for microtissue applications, using a systematic approach to tune the microgel properties based on a deep conceptual and practical understanding. Microscopic microgel design, such as the tailoring of the microg…

540 Chemistry and allied sciencesMaterials scienceIndolesPolymers and PlasticsPolymersMicrofluidicsBioengineeringNanotechnology02 engineering and technology010402 general chemistry01 natural sciencesBiomaterialsBiological propertyddc:570Materials ChemistryAnimalsNanoscopic scalechemistry.chemical_classificationMicrogelsRational designPolymer021001 nanoscience & nanotechnology0104 chemical sciencesSurface coatingTemplatechemistry540 ChemieSurface modification0210 nano-technologyGelsBiotechnologyMacromolecular bioscience
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In Vitro Evaluation of Enteric-Coated HPMC Capsules—Effect of Formulation Factors on Product Performance

2020

A comparative study on different enteric-coated hard capsules was performed. The influence of different formulation factors like choice of enteric polymer, triethyl citrate (TEC) concentration (plasticizer), talc concentrations (anti-tacking agent), and different coating process parameters on the sealing performance of the capsule and the disintegration time were investigated. Furthermore, the influence of different disintegration test methods (with disc vs. without disc and 50 mM U.S. Pharmacopoeia (USP) buffer pH 6.8 vs. biopredictive 15 mM phosphate buffer pH 6.5) was evaluated. All formulations showed sufficient but not equivalent acid resistance when tested. Polymer type was the main f…

AQOATcapsulesPharmaceutical Sciencelcsh:RS1-441formulationhypromellose phthalate (HPMCP)engineering.materialTalcBuffer (optical fiber)Articlelcsh:Pharmacy and materia medicachemistry.chemical_compoundCoatingTriethyl citratemedicineEudragit L100-55biopredictiveenteric-coatingchemistry.chemical_classificationChromatographydisintegrationChemistryPlasticizerCapsulePolymerEnteric coatinghypromellose acetate succinate (HPMCAS)engineeringmedicine.drugPharmaceutics
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Corrosion and wear resistance of coatings produced on AZ31 Mg alloy by plasma electrolytic oxidation in silicate-based K2TiF6 containing solution: Ef…

2022

Abstract In this research, plasma electrolytic oxidation coatings were prepared on AZ31 Mg alloy in a silicate-based solution containing K2TiF6 using bipolar and soft sparking waveforms with 10, 20, and 30% cathodic duty cycles. The coatings displayed a net-like surface morphology consisted of irregular micro-pores, micro-cracks, fused oxide particles, and a sintered structure. Due to the incorporation of TiO2 colloidal particles and the cathodic pulse repair effect, most of the micro-pores were sealed. Long-term corrosion performance of the coatings was investigated using electrochemical impedance spectroscopy during immersion in 3.5 wt.% NaCl solution up to 14 days. The coating grown by t…

AZ31 Mg alloyWear resistanceMaterials scienceAlloyPlasma electrolytic oxidationMetals and AlloysOxideCorrosion resistancePulsed waveformPlasma electrolytic oxidationengineering.materialCathodic protectionCorrosionDielectric spectroscopychemistry.chemical_compoundSettore ING-IND/23 - Chimica Fisica ApplicatachemistryCoatingMechanics of MaterialsengineeringComposite materialLayer (electronics)Dipotassium titanium hexafluoride
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Study of the electronic and atomic structure of thermally treated SrTiO3(110) surfaces

2003

The electronic structure of heated SrTiO3(110) surfaces was investigated with metastable impact electron spectroscopy and ultraviolet photoelectron spectroscopy (He(I). Scanning tunnelling microscopy and atomic force microscopy (AFM) were used to study the topology of the surface. The crystals were heated up to 1000 °C under reducing conditions in ultrahigh vacuum or under oxidizing conditions in synthetic air for 1 h, respectively. Under both conditions microfacetting of the surface is observed. The experimental results are compared with ab initio Hartree-Fock calculations, also presented here, carried out for both ideal and reconstructed SrTiO 3(110) surfaces. The results give direct evid…

Ab initioAnalytical chemistrySurfaces and InterfacesGeneral ChemistryElectronic structureCondensed Matter PhysicsElectron spectroscopySurfaces Coatings and Filmslaw.inventionCondensed Matter::Materials Sciencechemistry.chemical_compoundchemistryAb initio quantum chemistry methodslawMicroscopyMaterials ChemistryStrontium titanateAtomic physicsScanning tunneling microscopeUltraviolet photoelectron spectroscopySurface and Interface Analysis
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Crystal structure of sinhalite MgAlBO4 under high pressure

2015

We report on high-pressure angle-dispersive X-ray diffraction data up to 27 GPa for natural MgAlBO4 sinhalite mineral and ab initio total energy calculations. The experimental bulk modulus of sinhalite is B-0 = 171(3) GPa with a first-pressure derivative of B-0' = 4.2(3). A comparison with other olivine-type compounds shows that the value for B0 is 27% larger than that of Mg2SiO4 forsterite and 29% smaller than that of Al2BeO4 chrysoberyl. These differences are interpreted, on the basis of our ab initio calculations, in terms of the relative incompressibility of Al-O bonds in AlO6 octahedra (with a calculated bulk modulus of 250(1) GPa) as compared to Mg-O bonds in MgO6 octahedra (with a ca…

Ab initioSpinelSingle-crystalengineering.materialAb initio quantum chemistry methodsCationsPhysical and Theoretical ChemistryBulk modulusChrysoberylOlivineCompressionOxidesForsteriteGPASurfaces Coatings and FilmsElectronic Optical and Magnetic MaterialsCrystallographyChemistryGeneral EnergyPowder diffractionAugmented-wave methodFISICA APLICADAengineeringOrthorhombic crystal systemSingle crystalPowder diffraction
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Fast and blister-free irradiation conditions for cross-linking of PMMA induced by 2MeV protons

2013

For soft lithography, the conventional negative tone resists, such as SU-8, that are used to create the mold have a number of drawbacks. PMMA, which is normally used as a positive tone resist, can be used as a negative resist by using high-fluence irradiation conditions. In this report, we outline optimization of the irradiation conditions for PMMA thin films using 2MeV H^+ ions to exploit their ability to work as a negative tone resist at ion fluences above 1.0x10^1^5ionscm^-^2. The main aim was to induce cross-linking while maintaining the exposed regions free of blisters and maintaining short irradiation times. We found that by using a two-step process with a low-flux irradiation, follow…

Ability to workMaterials scienceta114BlistersPhotoresistCondensed Matter PhysicsAtomic and Molecular Physics and OpticsSoft lithographySurfaces Coatings and FilmsElectronic Optical and Magnetic MaterialsIonResistmedicineIrradiationElectrical and Electronic Engineeringmedicine.symptomComposite materialThin filmMicroelectronic Engineering
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