Search results for "code"
showing 10 items of 1180 documents
Biowaiver Monographs for Immediate-Release Solid Oral Dosage Forms: Codeine Phosphate
2014
The present monograph reviews data relevant to applying the biowaiver procedure for the approval of immediate-release multisource solid dosage forms containing codeine phosphate. Both biopharmaceutical and clinical data of codeine were assessed. Solubility studies revealed that codeine meets the "highly soluble" criteria according to World Health Organization (WHO), the European Medicines Agency (EMA), and the United States Food and Drug Administration (US FDA). Codeine's fraction of dose absorbed in humans was reported to be high (>90%) based on cumulative urinary excretion of drug and drug-related material following oral administration. The permeability of codeine was also assessed to be …
MAC-Engine
2011
In this demo, we prove that the flexibility supported by off-the-shelf IEEE 802.11 hardware can be significantly extended if we move the control of the MAC programming interface from the driver to the firmware, i.e. from the host CPU to the card CPU. To this purpose, we introduce the concept of MAC--Engine, that is an executor of Programmable Finite State Machines (PFSM) implemented at the firmware level: we show how the card itself can support different protocol logics thanks to PFSM bytecode representations that can be dynamically injected inside the card memory at run-time without incurring in down time issues or network disconnect events. We provide different PFSM examples in order to t…
Droit romain et Code Noir. Quelques réflexions a posteriori
2015
In Roman times, slavery is domestic, before conquests transformed its nature. Colonial slavery is an economic exploitation based on slave trade. How do the administrators apprehend the slave’s legal status ? Does the Code noir follow local rules or Roman precedents to supervise practice, according to some expected effects on the settlers’s property ? If Roman law serves as a matrix, is it as a simple recovery or as an indirect influence ? The spirit of antique solutions is present, but it is not essential for the legal definition of "Negros". The Roman law provides a conceptual tool to understand a posteriori the inner wheels of a specific status, at the turning point between property right…
Code rural et de la pêche maritime 2017
2017
13e édition, [textes à jour au 13 mars 2017], publié avec : Code forestier; National audience; Cette 13e édition intègre notamment :• la loi du 28 décembre 2016 de modernisation, de développement et de protection des territoires de montagne ;• la loi du 18 novembre 2016 de modernisation de la justice du XXIe siécle réformant ta désignation des assesseurs des tribunaux paritaires des baux ruraux ;• le décret du 25 octobre 2016 portant application de [ordonnance du 10 décembre 2015 relative aux garanties consistant en une prise de position formelle, opposable à [administration, sur [application d'une norme à la situation de fait ou au projet du demandeur ;• la loi du 8 août 2016 pour la recon…
Droit et philosophie à la lumière de l'Encyclopédie
2015
International audience; Quelle place occupe le droit dans l’Encyclopédie de Diderot et de D’Alembert ? Quels rapports le mouvement encyclopédique et l’esprit de la Déclaration des droits de 1789 entretiennent-ils ? Dans cette étude novatrice, Luigi Delia explore les enjeux du droit dans l’entreprise emblématique des Lumières.Encadrée par la publication de deux ouvrages fondamentaux – L’Esprit des lois de Montesquieu (1748) et le Traité des délits et des peines de Beccaria (1765) –, l’Encyclopédie propose une nouvelle conception de la justice en faisant dialoguer des cultures juridiques différentes, celle des juristes et celle des philosophes. À partir …
Saliva testing after single and chronic administration of dihydrocodeine.
2001
In the present study, concentrations of dihydrocodeine and its metabolites in saliva and serum were compared after single low-dose and chronic high-dosage administration of the drug. In the first investigation, blood and saliva were collected periodically from six subjects after oral administration of 60 mg dihydrocodeine. In the second study, 20 subjects on oral dihydrocodeine maintenance provided single samples of blood and saliva simultaneously. Serum protein binding of salivary analytes and their recovery from the adsorbing material of the collection device as well as pH values of saliva samples were determined. The fluids were analyzed for dihydrocodeine and the major metabolites by hi…
Influence of Pigmentation on the Codeine Content of Hair Fibers in Guinea Pigs
1997
Tortoise shell guinea pigs (n = 7) were administered codeine (1 mg/mL codeine-base) in their drinking water for 3 weeks. Black, reddish-brown and white hair was collected separately from each animal before and after treatment. The hair samples were analyzed by GC/MS. The experiment showed positive results for all hair fibers with large individual variability of drug incorporation. Low drug intake resulted in small differences of the drug content in hair fibers different in color, whereas in cases of high drug intake a strong influence of hair pigmentation on the analytical results was observed. The highest drug content was always found in black hair samples, non-pigmented hair showed the lo…
Embedded Model Control and dynamic simulation
2006
Embedded model control (EMC) is and end-to-end control technology addressed to industrial engineers and centered on the embedded model, a stylized discrete-time state equation of the whole plant, including environment, communication and computing resources. The embedded model, which is the core of the control unit, is derived and validated from a fine model of the plant which is implemented as a simulator code. The latter acts as a faithful and friendly test-bench where assessing control units before they are loaded into target processor. The paper illustrates the requirements and architecture of the EMC simulator under continuous improvement. A case study closes the paper.
Vector representation of non-standard spellings using dynamic time warping and a denoising autoencoder
2017
The presence of non-standard spellings in Twitter causes challenges for many natural language processing tasks. Traditional approaches mainly regard the problem as a translation, spell checking, or speech recognition problem. This paper proposes a method that represents the stochastic relationship between words and their non-standard versions in real vectors. The method uses dynamic time warping to preprocess the non-standard spellings and autoencoder to derive the vector representation. The derived vectors encode word patterns and the Euclidean distance between the vectors represents a distance in the word space that challenges the prevailing edit distance. After training the autoencoder o…
A quasi chemistry-transport model mode for EMAC
2010
Abstract. A quasi chemistry-transport model mode (QCTM) is presented for the numerical chemistry-climate simulation system ECHAM/MESSy Atmospheric Chemistry (EMAC). It allows for a quantification of chemical signals through suppression of any feedback between chemistry and dynamics. Noise would otherwise interfere too strongly. The signal is calculated from the difference of two QCTM simulations, a reference simulation and a sensitivity simulation. In order to avoid the feedbacks, the simulations adopt the following offline chemical fields: (a) offline mixing ratios of radiatively active substances enter the radiation scheme, (b) offline mixing ratios of nitric acid enter the scheme for re-…