Search results for "coding"
showing 10 items of 920 documents
A new subtype of hepatitis C virus genotype 1: complete genome and phylogenetic relationships of an Equatorial Guinea isolate.
2006
Hepatitis C virus (HCV) is the leading cause of chronic liver disease and is associated with hepatocellular carcinoma. However, there have been few studies on the distribution and genetic diversity of HCV isolates in non-developed countries. Here, the complete genome sequence of an HCV genotype 1 isolate from Equatorial Guinea is reported, the first complete HCV-1 genome of African origin. Phylogenetic analysis revealed that this sequence always grouped with sequences of genotype 1, but did not group clearly with any subtype described so far. An analysis of partial NS5B gene sequences with additional sequences of African origin also failed to find close similarities between the new sequenc…
Effect of traffic proximity of lung function in asthmatic children
2014
Introduction Respiratory conditions are strongly dependent on air pollution. Urban areas are typically characterized by risky environmental conditions, especially due to traffic congestion. Indeed, there may be important variations in environmental quality even within urban areas. Objectives To analyze the effect of traffic proximity on asthma and to explore the relationship between level of traffic proximity and lung function in both asthmatic children and non-asthmatic children. Methods A case-control study on children visited for suspected respiratory diseases at IBIM from September 2011 to May 2014 was performed. All the children have been geocoded according to their residence address. …
SOLUZIONI OPERATIVE ED ASPETTI QUALITATIVI PER LA GEOCODIFICA DI POPOLAZIONI IN AMBITO SANITARIO.
2015
IntroduzioneL'utilizzo dei Geographic Information Systems (GIS) in ambito sanitario, continua a ricevere grande attenzione. La disponibilità di informazioni sulla localizzazione degli individui, consente di effettuare associazioni territoriali sulle cause delle patologie, nonché di indagare aspetti legati alla distribuzione dei servizi sanitari ed all'equità di accesso alle cure. ObiettiviAnalizzare le principali problematiche e le soluzioni operative per la geocodifica di popolazioni e proporre un indice di qualità della geocodifica di cui poter tenere conto in sede di analisi. MetodiCome caso studio vengono illustrate le fasi che hanno portato alla georeferenziazione di indirizzi residenz…
Age-Related Changes in Predictive Capacity Versus Internal Model Adaptability: Electrophysiological Evidence that Individual Differences Outweigh Eff…
2015
Hierarchical predictive coding has been identified as a possible unifying principle of brain function, and recent work in cognitive neuroscience has examined how it may be affected by age related changes. Using language comprehension as a test case, the present study aimed to dissociate age-related changes in prediction generation versus internal model adaptation following a prediction error. Event related brain potentials (ERPs) were measured in a group of older adults (60-81 years; n = 40) as they read sentences of the form "The opposite of black is white/yellow/nice." Replicating previous work in young adults, results showed a target related P300 for the expected antonym ("white"; an eff…
Zebrafish Reveals Different and Conserved Features of Vertebrate Neuroglobin Gene Structure, Expression Pattern, and Ligand Binding
2004
Neuroglobin has been identified as a respiratory protein that is primarily expressed in the mammalian nervous system. Here we present the first detailed analysis of neuroglobin from a non-mammalian vertebrate, the zebrafish Danio rerio. The zebrafish neuroglobin gene reveals a mammalian-type exon-intron pattern in the coding region (B12.2, E11.0, and G7.0), plus an additional 5'-non-coding exon. Similar to the mammalian neuroglobin, the zebrafish protein displays a hexacoordinate deoxy-binding scheme. Flash photolysis kinetics show the competitive binding on the millisecond timescale of external ligands and the distal histidine, resulting in an oxygen affinity of 1 torr. Western blotting, i…
DNase I sensitivity of the chromatin of the yeast SUC2 gene for invertase.
1986
The DNase I sensitivity of chromatin of the yeast SUC2 gene, which encodes two forms of invertase, has been studied both in the genome and in a multicopy plasmid carrying the gene and its flaking sequences. Whereas little if any difference in the DNase I sensitivity of the flanking regions was found between the repressed and the derepressed states, derepression of the gene was accompanied by a large increase in the sensitivity of the transcribed region. A well-defined DNase I hypersensitive site was found centered at approximately 120 bp downstream from the end of the coding region. This site seems to be flanked in the 3' non-coding region by strictly positioned nucleosomes, and the structu…
ARQ Aware Scheduling for the IEEE 802.16 Base Station
2008
The IEEE 802.16 technology defines the ARQ mechanism that enables a connection to resend data at the MAC level if an error is detected. In this paper, we analyze the ARQ aware scheduling for the 802.16 base station. In particular, we consider how the BS scheduler can account for the ARQ block size, absence of the ARQ block rearrangement, and the ARQ transmission window. We propose a set of constraints that can be applied to any base station scheduler algorithm. To test them, we run a number of simulation scenarios. The simulations results confirm that the ARQ aware scheduling can improve the overall performance.
Performance analysis of the ieee 802.16 arq mechanism
2007
The IEEE 802.16 technology defines the ARQ mechanism that enables a connection to resend data at the MAC level if an error is detected. In this paper, we analyze the key features and parameters of the 802.16 ARQ mechanism. In particular, we consider a choice for the ARQ feedback type, an algorithm to build block sequences, a scheduling of the ARQ feedbacks and retransmissions, the ARQ block rearrangement, ARQ transmission window and ARQ block size. We run a number of simulation scenarios to study these parameters and how they impact a performance of application protocols. The simulation results reveal that the ARQ mechanism and its correct configuration play an important role in transmittin…
On ARQ feedback intensity of the IEEE 802.16 ARQ mechanism
2008
The IEEE 802.16 standard defines the ARQ mechanism as a part of the MAC layer. The functioning of the ARQ mechanism depends on a number of parameters. The IEEE 802.16 specification defines them but it does not provide concrete values and solutions. We ran simulation scenarios to study how the ARQ feedback intensity impacts the performance of application protocols. The simulation results reveal that a low ARQ feedback intensity results only in a marginal improvement. Though it is possible to optimize the ARQ feedback intensity, it is reasonable to rely upon more frequent ARQ feedback messages as they do not result in a performance degradation. At the same time, ARQ connections, which work on…
Modulation of base excision repair of 8-oxoguanine by the nucleotide sequence.
2013
8-Oxoguanine (8-oxoG) is a major product of oxidative DNA damage, which induces replication errors and interferes with transcription. By varying the position of single 8-oxoG in a functional gene and manipulating the nucleotide sequence surrounding the lesion, we found that the degree of transcriptional inhibition is independent of the distance from the transcription start or the localization within the transcribed or the non-transcribed DNA strand. However, it is strongly dependent on the sequence context and also proportional to cellular expression of 8-oxoguanine DNA glycosylase (OGG1)-demonstrating that transcriptional arrest does not take place at unrepaired 8-oxoG and proving a causal…