Search results for "cognitive neuroscience"

Evgeny Nikolaevich Sokolov (1920-2008).

2008

Neurocognitive endophenotypes (endophenocognitypes) from studies of relatives of bipolar disorder subjects: a systematic review.

2008

Abstract Background There is growing interest to research neurocognition as a putative endophenotype for subjects with bipolar disorders (BD). The authors sought to review the available literature focused on relatives of subjects with bipolar disorder (BD-Rels) and identify suitable cognitive candidates to endophenotypes or endophenocognitypes. Method A systematic review was conducted in Medline, EMBASE and PsycINFO databases (1980–July 2007), supplemented with a manual search of reference lists. Results Twenty-three cross-sectional papers of discordant twins (4 studies), genetic high-risk subjects (7), and different BD-Rel groups (12) met the inclusion criteria and evaluated 532 BD-Rels. I…

Psychomotor slowness is associated with self-reported sleep duration among the general population

2010

Short and long self‐reported sleep durations have been found to be associated with several seemingly disparate health risks and impaired functional abilities, including cognitive functioning. The role of long sleep is especially poorly understood in this context. Psychomotor slowness, shown to have analogous associations with cognitive performance and health risks as self‐reported long sleep duration, has not been studied together with sleep duration in epidemiological settings. We hypothesized that self‐reported habitual sleep duration, especially long sleep, is associated with slow psychomotor reaction time, and that this association is independent of vigilance‐related factors. The hypoth…

Brain Slow Potentials and Postural Sway Behavior During Sharpshooting Performance.

1999

In the present study, the relation of preparatory brain slow potentials (SPs) to postural body sway during sharpshooting performance was examined. SPs from frontal, left-central, and right-central areas were recorded from 6 elite and 6 non-elite sharpshooters during a realistic simulated shooting task. A force platform technique was used in the recording of postural sway. The results showed that body sway, as indexed by sway amplitude and mean velocity, was associated with the concomitant SP changes. That relationship was dependent on the shooter's expertise level, however. The main finding among the elite shooters was that the reduced amplitude of body sway coincided with reduced frontal p…

Semantic context-processing deficit in thought-disordered schizophrenic patients: Evidence from new semantic priming paradigms

2006

Introduction. Disorders in the processing of the semantic context are now a well-established phenomenon in thought-disordered (TD) schizophrenic patients, and have been revealed especially well by studies that have made use of the experimental paradigm of lexical decision tasks coupled with semantic priming. The main question addressed by this study was the evaluation of the experimental conditions under which TD schizophrenic patients are able to deploy cognitive strategies for semantic context processing. Methods. We studied semantic priming in two double lexical decision tasks (i.e., involving the explicit processing of the prime word) using a sequential presentation of words (stimulus o…

Auditory temporal processing in schizophrenia: high level rather than low level deficits?

2006

INTRODUCTION: Patients with schizophrenia demonstrate a wide range of information processing deficits. Most recent studies argue in favour of high level deficits, including attention and context processing, whereas fewer studies have demonstrated deficits at earlier stages of processing, such as perceptual discrimination and organisation. This is the first study to investigate both high and low level processing, within a single paradigm, in the case of auditory temporal processing in schizophrenia. METHODS: Patients with schizophrenia were compared to controls on a series of tasks involving three auditory temporal processes varying from low to higher level: (1) segregation of a complex sequ…

Advancing psychotherapy and evidence-based psychological interventions

2013

Psychological models of mental disorders guide research into psychological and environmental factors that elicit and maintain mental disorders as well as interventions to reduce them. This paper addresses four areas. (1) Psychological models of mental disorders have become increasingly transdiagnostic, focusing on core cognitive endophenotypes of psychopathology from an integrative cognitive psychology perspective rather than offering explanations for unitary mental disorders. It is argued that psychological interventions for mental disorders will increasingly target specific cognitive dysfunctions rather than symptom-based mental disorders as a result. (2) Psychotherapy research still lack…

Acetaldehyde, motivation and stress: Behavioral evidence of an addictive ménage à trois

2017

Acetaldehyde contributes to alcohol’s psychoactive effects through its own rewarding properties. Recent studies shed light on the behavioral correlates of acetaldehyde administration and the possible interactions with key neurotransmitters for motivation, reward and stress-related response, such as dopamine and endocannabinoids. This mini review critically examines acetaldehyde psychoactive properties, focusing on behavioral investigations able to unveil acetaldehyde motivational effects and their pharmacological modulation in vivo. Similarly to alcohol, rats spontaneously drink acetaldehyde, whose presence is detected in the brain following chronic self-administration paradigm. Acetaldehyd…

Expand your body when you look at yourself: The role of the posture in a mirror exposure task

2018

Mirror exposure (ME) is one of the main components of the treatment of patients with eating disorders symptomatology and it has shown its effectiveness in improving several outcomes (e.g., body dissatisfaction). However, the study as to what body posture should be adopted to maximize its effectiveness has been neglected. From embodied cognition and emotion theories, the adoption of an expansive (vs. contractive) body posture has been associated with positive changes in cognitive and emotional responses. The objective of this study was to analyze the effect of adopting an expansive (vs. contractive) posture before an ME task on body-related emotions and cognitions, as well as to analyze the …

The Minimal Phenomenal Experience questionnaire (MPE-92M): Towards a phenomenological profile of “pure awareness” experiences in meditators

2021

Objective To develop a fine-grained phenomenological analysis of “pure awareness” experiences in meditators. Methods An online survey in five language versions (German, English, French, Spanish, Italian) collected data from January to March 2020. A total of 92 questionnaire items on a visual analogue scale were submitted to exploratory and confirmatory factor analysis. Results Out of 3627 submitted responses, 1403 were usable. Participants had a median age of 52 years (range: 17–88) and were evenly split between men and women (48.5% vs 50.0%). The majority of meditators practiced regularly (77.3%), were free of diagnosed mental disorders (92.4%) and did not regularly use any psychoactive s…