Search results for "coma"

Infezione da HHV8 e leucemia linfoblastica acuta in età pediatrica

2003

HHV8 è un virus erpetico correlato, sulla base di dati ormai concordi, al sarcoma di Kaposi (KS), al linfoma effusivo primario ed alla Ma- lattia di Castleman multicentrica. Tale virus è stato inoltre associato con altre patologie tumorali ma gli studi in proposito non sono stati confermati. Poco, d’altra parte, si conosce sulle modalità prevalenti di trasmissione del virus, probabilmente diverse nelle nazioni industrializzate ed in quelle in via di sviluppo. In Sicilia una elevata prevalenza del KS clas- sico era già presente in epoca pre-AIDS. Abbiamo condotto uno studio sierologico in immunofluorescenza per rilevare gli anticorpi anti-HHV8 in 40 bambini con leucemia linfoblastica acuta (…

Low risk of intracranial emergency in patients with minor head injury treated with antiplatelet therapy.

2021

PROX1 transcription factor controls rhabdomyosarcoma growth, stemness, myogenic properties and therapeutic targets

2022

Funding Information: ACKNOWLEDGMENTS. We would like to thank Dr. Tuomas Tammela and Dr. Monika Ehnmann for providing RMS cell lines and Dr. Jenny Högström for discussions and comments during the project. Kirsi Mattinen, Jefim Brodkin, Maxime Laird, Manon Gruchet, Ilse Paetau, Tanja Laakkonen, and Tapio Tainola are acknowledged for their excellent technical help. We also thank the Laboratory Animal Center at the University of Helsinki for expert animal care, the Biomedicum Imaging Unit for microscope support, the Biomedicum Functional Genomics Unit for the RNAseq experiments and the FIMM Technology Centre High Throughput Biomedicine for the drug sensitivity and resistance testing. Our first …

Marcos y la sociedad civil global

2001

SICILIAN NATURALISTIC NEWS: 8 Muscicapa striata tyrrhenica; 9 Garella (Characoma) nilotica; 10 Mycterus curculioides.

2021

SICILIAN NATURALISTIC NEWS: 8 aMediterranean Flycatcher Muscicapa striata tyrrhenica Schiebel, 1910 (Aves Muscicapidae); 9 Garella (Characoma) nilotica (Rogenhofer, 1881) (Lepidoptera Nolidae) 10 Mycterus curculioides Fabricius, 1781 (Coleoptera Mycteridae)

Damage to the urinary tract secondary to irradiation.

1995

During the past two decades, highly effective multimodality therapy with surgery, chemotherapy and irradiation has been developed through consecutive national and international study protocols for childhood genitourinary cancers, the model being Wilms' tumor. These studies represent a landmark achievement in the history of pediatric oncology and mark the success of multi-institutional efforts. Now that excellent survival rates have been established, current interest is now directed primarily at examination of survivors for long-term treatment complications and minimizing the side effects while preserving treatment efficacy. Treatment sequelae may not become evident until many years after th…

Genitourinary cancer in childhood

1993

Nerva nell'Epitome de Caesaribus

2007

L’ampio e documentato capitolo che l’Epitome de Caesaribus dedica al breve impero di Nerva mette in luce l'interesse dell’anonimo autore per diversi aspetti del periodo. In particolare evidenza sono i dati originali che l’Epitome apporta in materia di politica fiscale e di liberalitas imperiale, l’accurata descrizione di specifici eventi in cui si segnala l’ostilità dello storico nei confronti dei milites che agiscono con violenza e disprezzo della volontà imperiale, e la rappresentazione di personaggi che hanno avuto relazione con l’ambiente di corte. Emerge così il peculiare giudizio dello storico su Nerva: l’epitomatore è sfuggito al rischio di appiattimento indotto dalla preponderante f…

The role of glia, mitochondria, and the immune system in glaucoma.

2009

Author(s): Tezel, Gulgun; Fourth ARVO/Pfizer Ophthalmics Research Institute Conference Working Group

Functional characterization of protein variants of the human multidrug transporter ABCC2 by a novel targeted expression system in fibrosarcoma cells

2012

The multidrug resistance-associated protein 2 (MRP2/ABCC2) is involved in the efflux of endogenous and xenobiotic substrates, including several anticancer and antiviral drugs. The functional consequences of ABCC2 protein variants remain inconsistent, which may be due to shortcomings of the in vitro assays used. To study systematically the functional consequences of nonsynonymous ABCC2 variants, we used a novel “Screen and Insert” (ScIn) technology to achieve stable and highly reproducible expression of 13 ABCC2 variants in HT1080 cells. Western blotting revealed lower (30–65%) ABCC2 expression for D333G, R1174H, and R1181L as compared with wild type (WT; 100%), whereas the linked variant V1…