Search results for "combination"

showing 10 items of 1379 documents

Comparison of Variance and Damage Indicator Methods for Prediction of the Fracture Plane Orientation in Multiaxial Fatigue

1999

ABSTRACT Two methods that enable prediction of the fracture plane orientation are presented and compared in this paper. The first one is a statistical approach, which is based on the variance of an equivalent stress. It is assumed that the fracture plane is the one where the variance of a linear combination of the shear and normal stresses acting on this plane is maximum. The second one uses the so-called damage indicator of a multiaxial fatigue criterion, which is based on the research of the critical plane. The formulation of the criterion involves shear and normal stress amplitudes and mean normal stress. The fracture plane is the critical plane; That is to say the one where the damage i…

Stress (mechanics)Equivalent stressVariance methodAmplitudeMaterials scienceShear (geology)business.industryStructural engineeringFracture planeLinear combinationbusinessStress intensity factor
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Analysis of the influence of processor hidden registers on the accuracy of fault injection techniques

2004

Modern processors tend to increase the number of registers, being part of them not accessible by the instruction set. Traditionally, the effect of faults in these hidden registers has not been considered during system validation using fault injection. In this paper, a study of the importance of faults in hidden registers is performed. Firstly, we have analysed the sensitivity of hidden registers to faults in combinational logic. In a second phase, we have analysed the impact of the faults occurred in hidden registers on system behaviour. A broad set of permanent and transient faults have been injected into the models of two typical commercial microcontrollers, using a VHDL-based fault injec…

Stuck-at faultInstruction setCombinational logicComputer scienceFault coverageVHDLHardware description languageHardware_PERFORMANCEANDRELIABILITYParallel computingFault injectionFault modelcomputercomputer.programming_languageProceedings. Ninth IEEE International High-Level Design Validation and Test Workshop (IEEE Cat. No.04EX940)
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Lipid-Altering Efficacy of Ezetimibe/Simvastatin 10/20 mg Compared to Rosuvastatin 10 mg in High-Risk Patients with and without Type 2 Diabetes Melli…

2010

AIMS: This post hoc analysis compared the effects of switching to ezetimibe/simvastatin 10/20 mg (EZE/SIMVA) or rosuvastatin 10 mg (ROSUVA) in uncontrolled high-risk hypercholesterolemic patients with/without type 2 diabetes mellitus (T2DM) despite statin monotherapy. METHODS: Patients (n = 618) at high risk for coronary vascular disease with elevated LDL-C ≥100 and ≤190 mg/dL despite use of statins were randomized 1:1 to double-blind EZE/SIMVA 10/20 mg or ROSUVA 10 mg for 6 weeks. Patients were classified as having T2DM based on ≥1 of the following: diagnosis of T2DM, antidiabetic medication, or FPG ≥126 mg/dL. This analysis evaluated percent changes from baseline in lipids among patients …

SulfonamidesSimvastatinSettore MED/09 - Medicina InternaAnticholesteremic AgentsHypercholesterolemiaDrug ResistanceCholesterol LDLEzetimibeLipidsFluorobenzenesC-Reactive ProteinCholesterolPyrimidinesDiabetes Mellitus Type 2Double-Blind MethodOdds RatioDiabetes MellitusAzetidinesHumansDrug Therapy CombinationHydroxymethylglutaryl-CoA Reductase InhibitorsRosuvastatin CalciumApolipoproteins B
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Simulation of tungsten tip-Al(100) surface electronic structure through LCAO-LSD calculations

1997

Surface (mathematics)chemistryLinear combination of atomic orbitalschemistry.chemical_elementElectronic structurePhysical and Theoretical ChemistryAtomic physicsTungstenCondensed Matter PhysicsAtomic and Molecular Physics and OpticsInternational Journal of Quantum Chemistry
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The Use of a Surgical Patch in the Prevention of Lymphoceles After Extraperitoneal Pelvic Lymphadenectomy for Prostate Cancer: A Randomized Prospecti…

2009

Purpose: Pelvic lymphadenectomy is frequently performed simultaneously with radical prostatectomy to determine lymph node status and the most frequently recorded postoperative complication is the development of a symptomatic lymphocele. This study evaluated TachoSil® as an adjunct treatment in preventing lymphoceles after extraperitoneal pelvic lymphadenectomy for prostate cancer. Materials and Methods: A total of 60 consecutive patients who had undergone radical prostatectomy and pelvic lymphadenectomy were prospectively enrolled in this study. The patients were randomly assigned to a standard technique with the use of clips and electrocoagulation plus TachoSil, or to standard technique on…

Surgical SpongesMalemedicine.medical_specialtyUrologymedicine.medical_treatmentLymphocelePilot Projectscomplicationlymph node excisionLymphoceleDrug CombinationmedicineHumansPilot ProjectSingle-Blind MethodSurgical SpongeProspective StudiesProspective cohort studyPelvisprostatectomybusiness.industryProstatectomyThrombinProstatic NeoplasmsPostoperative complicationFibrinogenpelviTachoSilMiddle Agedmedicine.diseaseSurgeryDrug CombinationsProspective Studiemedicine.anatomical_structureProstatic NeoplasmLymphadenectomybusinessRadical retropubic prostatectomyHuman
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Induction of tumor peptide-specific cytotoxic T cells under serum-free conditions by mature human dendritic cells

2000

Tumor vaccination strategies using antigen-pulsed dendritic cells (DC) are currently under development. We established an in vitro system using cultured DC from HLA-typed volunteers for the induction of tumor peptide-specific CD8+ T cells. The strength and specificity of the resulting CTL responses were investigated. For stimulation of syngeneic CD8+ T cells two well-defined DC populations were generated: CD1a+ immature DC cultured in the presence of GM-CSF and IL-4 and mature CD83+ DC generated by additional stimulation with a cytokine cocktail. Stimulations were performed under serum-free conditions and in the absence of exogenous cytokines. Analysis of T cell responses showed that mature…

T cellImmunoglobulinsPriming (immunology)DermatologyDendritic cell differentiationCD8-Positive T-LymphocytesBiologyCulture Media Serum-FreeInterleukin 21Antigens CDmedicineHumansCytotoxic T cellCells CulturedCellular SenescenceMembrane GlycoproteinsCell DifferentiationDendritic CellsGeneral MedicineDendritic cellMolecular biologyNeoplasm ProteinsDrug CombinationsCTL*medicine.anatomical_structureImmunologyCytokinesCD8T-Lymphocytes Cytotoxic
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Taxonomic remarks onHieracium sartorianumvar.lucanicum(Asteraceae), a little known taxon of Cilento (Campania, southern Italy)

2015

Hieracium sartorianum var. lucanicum, a little known taxon described from Mt Sacro (Parco Nazionale del Cilento e Vallo di Diano, Prov. of Salerno, Campania, Italy), is reexamined. As a result it is reclassified as a subspecies to H. hypochoeroides. A new combination and lectotypification are made and a detailed description is given.

TaxonHieraciumbiologyCampania Cilento Hieracium hypochoeroides Monte Sacro taxonomy new combinationSettore BIO/02 - Botanica SistematicaBotanyPlant ScienceAsteraceaeSubspeciesbiology.organism_classificationEcology Evolution Behavior and SystematicsNordic Journal of Botany
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Chromatin modifiers and recombination factors promote a telomere fold-back structure, that is lost during replicative senescence.

2020

Telomeres have the ability to adopt a lariat conformation and hence, engage in long and short distance intra-chromosome interactions. Budding yeast telomeres were proposed to fold back into subtelomeric regions, but a robust assay to quantitatively characterize this structure has been lacking. Therefore, it is not well understood how the interactions between telomeres and non-telomeric regions are established and regulated. We employ a telomere chromosome conformation capture (Telo-3C) approach to directly analyze telomere folding and its maintenance in S. cerevisiae. We identify the histone modifiers Sir2, Sin3 and Set2 as critical regulators for telomere folding, which suggests that a dis…

TelomeraseProtein Folding:Chemicals and Drugs::Amino Acids Peptides and Proteins::Proteins::DNA-Binding Proteins::Rad52 DNA Repair and Recombination Protein [Medical Subject Headings]:Chemicals and Drugs::Amino Acids Peptides and Proteins::Proteins::Fungal Proteins::Saccharomyces cerevisiae Proteins [Medical Subject Headings]Gene ExpressionYeast and Fungal ModelsArtificial Gene Amplification and ExtensionQH426-470BiochemistryPolymerase Chain ReactionChromosome conformation captureHistonesCromatina0302 clinical medicineSirtuin 2Macromolecular Structure AnalysisSilent Information Regulator Proteins Saccharomyces cerevisiaeCellular Senescence:Organisms::Eukaryota::Fungi::Yeasts::Saccharomyces::Saccharomyces cerevisiae [Medical Subject Headings]0303 health sciencesChromosome BiologyEukaryota:Phenomena and Processes::Genetic Phenomena::Genetic Processes::DNA Replication [Medical Subject Headings]TelomereSubtelomere:Anatomy::Cells::Cellular Structures::Intracellular Space::Cell Nucleus::Cell Nucleus Structures::Intranuclear Space::Chromosomes::Chromosome Structures::Telomere [Medical Subject Headings]Chromatin3. Good healthChromatinCell biologyNucleic acidsTelomeres:Phenomena and Processes::Cell Physiological Phenomena::Cell Physiological Processes::Cell Cycle::Cell Division::Telomere Homeostasis [Medical Subject Headings]Experimental Organism SystemsDaño del ADNEpigeneticsResearch ArticleSenescenceDNA Replication:Chemicals and Drugs::Enzymes and Coenzymes::Enzymes::Hydrolases::Amidohydrolases::Histone Deacetylases [Medical Subject Headings]Chromosome Structure and FunctionProtein StructureSaccharomyces cerevisiae ProteinsSaccharomyces cerevisiaeBiologyResearch and Analysis MethodsHistone DeacetylasesChromosomes03 medical and health sciencesSaccharomycesModel Organisms:Chemicals and Drugs::Enzymes and Coenzymes::Enzymes::Transferases::One-Carbon Group Transferases::Methyltransferases [Medical Subject Headings]:Chemicals and Drugs::Amino Acids Peptides and Proteins::Proteins::Intracellular Signaling Peptides and Proteins::Sirtuins::Sirtuin 2 [Medical Subject Headings]:Chemicals and Drugs::Amino Acids Peptides and Proteins::Proteins::Fungal Proteins::Saccharomyces cerevisiae Proteins::Silent Information Regulator Proteins Saccharomyces cerevisiae [Medical Subject Headings]DNA-binding proteinsGenetics:Chemicals and Drugs::Enzymes and Coenzymes::Enzymes::Recombinases::Rec A Recombinases::Rad51 Recombinase [Medical Subject Headings]Molecular Biology TechniquesMolecular Biology030304 developmental biologyCromosomasSenescencia celularOrganismsFungiBiology and Life SciencesProteinsTelomere HomeostasisCell BiologyDNAMethyltransferasesG2-M DNA damage checkpointProteína recombinante y reparadora de ADN Rad52YeastTelomereRad52 DNA Repair and Recombination ProteinRepressor ProteinsAnimal Studies:Chemicals and Drugs::Amino Acids Peptides and Proteins::Proteins::Transcription Factors::Repressor Proteins [Medical Subject Headings]DNA damageRad51 RecombinaseHomologous recombination030217 neurology & neurosurgeryTelómeroDNA DamagePLoS Genetics
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Integrazione di celle fotovoltaiche ibride nel vetromattone

2012

L’invenzione riguarda l’integrazione del vetromattone con celle solari ibride (organiche/inorganiche), conosciute come Dye-sensitized Solar Cell (DSC). La combinazione del vetromattone con le DSC consente di migliorare le prestazioni del prodotto originario rendendolo in grado di produrre energia pulita. Le caratteristiche di trasparenza e isolamento termo-acustico del prodotto possono essere regolate agendo sulla configurazione delle DSC. Il prodotto può essere assemblato a formare pannelli fotovoltaici per la realizzazione di facciate traslucide energeticamente “attive” in varie condizioni luminose (condizioni di luce diffusa o artificiale) e indipendentemente dall’angolo di radiazione so…

The integration of Dye-sensitized Solar Cell (DSC) with the glassblock is disclosed. The combination of the two technological elements the glassblock and the DSC module enhance their own peculiarities. The final complete product is ready-made for installation owns the qualities of the glassblock and produces sustainable energy at the same time. The transparency and the thermo-acoustic insulation may be modulated according to the specific requirements of each case of installation. The product may be used for example to create PV panels for glazed and translucent façades that are able to perform efficiently in all light conditions (even in diffuse light also converting internal artificial light) that are not dependant on the angle of the solar radiation and do not suffer from the high operative temperatures of functioning due to the peculiarities of the DSCs. DSCs are made of economic and biocompatible materials and are produced with low-cost and highly productive printing methods on rigid or flexible substrates. With the integration of DSC modules with the glassblock PV panels coincide with the envelope itself so that they do not need any further structures to be installed on and allow the possibility of subtract from the price of the panel the price of the substituted building element allowing further economies. DSCs can be printed in different colours and with various patterns offering to designers and customers the possibility of intervening on the glassblock aesthetical aspect also taking advantage of the peculiar modularity of the glassblock for larger compositions of drawings on the building’s façade. Seven Hypotheses of integration are discussed in order to obtain DSC-integrated glassblock ready for the construction of a precast and dry-assembled PV panel which can use the horizontal and vertical cavities between the glassblocks to house plastic profiles where the electric interconnections and the steel bars -useful for improve the mechanical resistance of the panel- are integrated.Settore ICAR/10 - Architettura Tecnica
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Canopy Architecture Appraisal by Fractal Dimension of 'Flordastar' Peach Trees Grafted onto Different Rootstocks

2007

The objective of this research was to evaluate the modification of canopy architecture of ''Flordastar'' peach (Prunus persica L. Batsch) grafted onto rootstocks with different vigour, by the use of fractal dimension (D). The hypothesis was that different vigour rootstocks are able to modify the complexity of the branching pattern and that this effect can be assessed by a geometric parameter such as the fractal dimension (D) of the 2D projection of tree branching structure. The observations were carried out in a four-year-old experimental orchard of cv. ''Flordastar'' peach trees grafted onto Ishtara, Barrier, GF677 and MrS 2/5 rootstocks. On digital pictures of leafless, dormant peach tree…

The objective of this research was to evaluate the modification of canopy architecture of ''Flordastar'' peach (Prunus persica L. Batsch) grafted onto rootstocks with different vigour by the use of fractal dimension (D). The hypothesis was that different vigour rootstocks are able to modify the complexity of the branching pattern and that this effect can be assessed by a geometric parameter such as the fractal dimension (D) of the 2D projection of tree branching structure. The observations were carried out in a four-year-old experimental orchard of cv. ''Flordastar'' peach trees grafted onto Ishtara Barrier GF677 and MrS 2/5 rootstocks. On digital pictures of leafless dormant peach trees the tree skeleton was manually depicted by an image analysis software to measure total length and angles of insertion of branches. Bitmaps of the skeleton were then subjected to a specific software (FDCALC) able to calculate D by the "box counting" method. To account for the error introduced by analyzing a three dimensional structure with its 2D projection measurements were done on two images per tree taken from two different viewing angles. Results are shown in relation to tree vigour of the scion/stock combination. Fractal dimension was related to the vigour ranking of the graft combinations tested. In particular vigorous scion/stock combinations showed the highest D.HorticultureCanopy architectureHorticultureRootstockFractal dimensionMathematics
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