Search results for "compactibility"

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Influence of the parameters molecular structure and granularity on the compactibility of a powder

1995

Drug Dev. Ind. Pharm. ISI Document Delivery No.: RP128 Times Cited: 3 Cited Reference Count: 14 Andres, c ndiaye, a thomas, c tromelin, a chaillot, b pourcelot, y; International audience; The aim of this study was to determine whether it is possible to obtain better characterization of materials in order to find out if these one are suitable in Quality Assurance for direct tableting. We tried to show that a methodological approach combining chemical, physical and technological aspects could control the direct compression process. We chose orthoboric acid as a study model for the direct compression. From a chemical point of view, our findings show only one crystalline molecular structure (RX…

Materials sciencePharmaceutical Sciencemolecular structure02 engineering and technologypowdergranularity030226 pharmacology & pharmacy03 medical and health sciencesTableting0302 clinical medicineRheology[CHIM.ANAL]Chemical Sciences/Analytical chemistryDrug DiscoveryMoleculePharmacologyOrganic Chemistry021001 nanoscience & nanotechnologyCompression (physics)Characterization (materials science)[CHIM.THEO]Chemical Sciences/Theoretical and/or physical chemistryCrystallography[SDV.SP.PG]Life Sciences [q-bio]/Pharmaceutical sciences/Galenic pharmacologyGas pycnometerHomogeneouscompactibilityGranularity0210 nano-technologyBiological system
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