Search results for "compatibility"

The Cytocompatibility of Silver Diamine Fluoride on Mesenchymal Stromal Cells from Human Exfoliated Deciduous Teeth : An In Vitro Study

2022

Silver diamine fluoride (SDF) has been used for many years for the treatment of caries, and minimally invasive dentistry concepts have made it popular again. The fact that its application does not require the administration of anesthesia makes its use in children more desirable. The aim of this study was to determine the cytotoxicity of two new commercial SDF products: Riva Star (SDI Dental Limited) and e-SDF (Kids-e-Dental) on mesenchymal stromal cells from human exfoliated deciduous teeth (SHEDs). SHEDs were exposed to SDF products at different concentrations (0.1%, 0.01% and 0.005%). Then different assays were performed to evaluate their cytocompatibility on SHEDs: IC50, MTT, cell migrat…

Is the European Commission a hothouse for supranationalism? : theorising and exploring the world of Commission civil servants

2005

Does the European Commission (Commission) manage to transform and re-direct the roles played by Commission civil servants? To test the old neo-functionalist claim on loyalty transfer among civil servants, this article provides fresh survey and interview data on seconded national experts in the Commission. The transformative powers of the Commission are tested by assessing the extent to which seconded national experts adopt supranational role perceptions. Theoretically, the emergence of supranational role perceptions is accounted for by considering (i) processes of pre-socialisation outside the Commission, (ii) processes of resocialisation inside the Commission, and (iii) organisational inco…

The economics of platform competition: compatibility, standardization and piracy

2013

This thesis studies the platform competition with compatibility, standardization and piracy. In the first chapter we study the role played by expectations, the strength of the network externality and product differentiation in the strategic decisions of the platforms regarding compatibility and price competition. The decision problem is modeled as a two-stage game. In the first stage platforms simultaneously and non-cooperatively choose the degree of compatibility and in the second stage platforms compete in prices. More specifically, we solve a two-stage game in which duopolists decide simultaneously and non cooperatively the degree of compatibility between their products and they compete …

Toxicity of Dental Amalgams vs Composite Resins

2016

Ideal qualities of dental materials should include, in terms of biocompatibility, passivity towards oral tissues, so the material should not contain any leachable toxic and diffusible substances, neither release any harmful substance that can cause in time side effects, locally or generally. Even if amalgams are a group of dental materials with a long recorded history, many practitioners blame them, in contradiction with composite resins, especially for releasing free mercury into the body. On the other side, composite resins have reached great biocompatibility specifications, but also have many qualities that need more research, especially long term type.

Innovative technologies for temporary architecture

2009

Problem risen from temporariness and flexibility concepts of built concern, always constituted, all over technological advanced countries and throughout the whole history of scientific research, some of the most interesting aspects of technologies, industry and industrialization processes. Several project proposals about really light structures easily gatherable, transportable, that can be dismantled and reconverted, are proves of that such as their use in order to obtain flexible and functional living solutions. They are systems adaptable to different needs and fit to offer a concrete solution for the necessities related to the new ways of living. In fact temporary buildings that were thou…

Pressure-Dependent Tuning of Photoluminescence and Size Distribution of Carbon Nanodots for Theranostic Anticancer Applications

2020

Carbon nanodots (CDs) have recently attracted attention in the field of nanomedicine because of the biocompatibility, cost-effective nature, high specific surface, good near infrared (NIR) photothermal conversion into heat and tunable fluorescence properties, which have paved the way toward incorporating use of CDs into innovative anticancer theranostic platforms. However, a reliable synthesis of CDs with established and controlled physiochemical proprieties is precluded owing to the lack of full manipulation of thermodynamic parameters during the synthesis, thus limiting their use in real world medical applications. Herein, we developed a robust solvothermal protocol which allow fine contr…

The growth of knowledge : an inquiry into the Kuhnian theory

2009

Metabolic Changes in Tumor Microenvironment: How Could They Affect γδ T Cells Functions?

2021

The metabolic changes that occur in tumor microenvironment (TME) can influence not only the biological activity of tumor cells, which become more aggressive and auto sustained, but also the immune response against tumor cells, either producing ineffective responses or polarizing the response toward protumor activity. γδ T cells are a subset of T cells characterized by a plasticity that confers them the ability to differentiate towards different cell subsets according to the microenvironment conditions. On this basis, we here review the more recent studies focused on altered tumor metabolism and γδ T cells, considering their already known antitumor role and the possibility of manipulating th…

Human Papillomavirus Type 16 E7 Peptide-Directed CD8+ T Cells from Patients with Cervical Cancer Are Cross-Reactive with the Coronavirus NS2 Protein

2003

ABSTRACTHuman papillomavirus type 16 (HPV16) E6 and E7 oncoproteins are required for cellular transformation and represent candidate targets for HPV-specific and major histocompatibility complex class I-restricted CD8+-T-cell responses in patients with cervical cancer. Recent evidence suggests that cross-reactivity represents the inherent nature of the T-cell repertoire. We identified HLA-A2 binding HPV16 E7 variant peptides from human, bacterial, or viral origin which are able to drive CD8+-T-cell responses directed against wild-type HPV16 E7 amino acid 11 to 19/20 (E711-19/20) epitope YMLDLQPET(T) in vitro. CD8+T cells reacting to the HLA-A2-presented peptide from HPV16 E711-19(20)recogni…