Search results for "complex"

The mitotic spindle protein SPAG5/Astrin connects to the Usher protein network postmitotically

2011

Abstract Background Mutations in the gene for Usher syndrome 2A (USH2A) are causative for non-syndromic retinitis pigmentosa and Usher syndrome, a condition that is the most common cause of combined deaf-blindness. To gain insight into the molecular pathology underlying USH2A-associated retinal degeneration, we aimed to identify interacting proteins of USH2A isoform B (USH2AisoB) in the retina. Results We identified the centrosomal and microtubule-associated protein sperm-associated antigen (SPAG)5 in the retina. SPAG5 was also found to interact with another previously described USH2AisoB interaction partner: the centrosomal ninein-like protein NINLisoB. Using In situ hybridization, we foun…

Estimating soil loss of given return period by USLE-M-type models

2020

Many field investigations have clearly shown that rare and severe events control total soil erosion occurring over a long time period with up to 92% of total soil erosion over a 7‐year period resulting from just three daily events. Therefore, soil conservation strategies should be developed taking into account large events rather than long‐term average erosion. From an engineering point of view, establishing the soil loss of a given return period is needed. This can be obtained by the frequency analysis of soil loss measurements or by suitable soil erosion models. The USLE‐M modified and USLE‐M based are two empirical Universal Soil Loss Equation‐Modified (USLE‐M) type models which were dev…

"Sia de mercè sua girar sos clements ulls vers aquesta sua ciutat". La complexa relació de Ferran II i Barcelona

2017

Reyn kuvio (Rey-Osterrieth Complex Figure, ROCF) toiminnanohjauksen mittarina

2008

Improving the rheometry of rubberized bitumen: experimental and computation fluid dynamics studies

2017

Abstract Multi-phase materials are common in several fields of engineering and rheological measurements are intensively adopted for their development and quality control. Unfortunately, due to the complexity of these materials, accurate measurements can be challenging. This is the case of bitumen-rubber blends used in civil engineering as binders for several applications such as asphalt concrete for road pavements but recently also for roofing membranes. These materials can be considered as heterogeneous blends of fluid and particles with different densities. Due to this nature the two components tends to separate and this phenomenon can be enhanced with inappropriate design and mixing. Thi…

Root-induced decomposer growth and plant N uptake are not positively associated among a set of grassland plants

2007

Abstract It is known that plant species can induce development of different soil decomposer communities and that they differ in their influence on organic matter decomposition and N mineralization in soil. However, no study has so far assessed whether these two observations are related to each other. Based on the hypothesis that root-induced growth of soil decomposers leads to accelerated decomposition of SOM and increased plant N availability in soil, we predicted that (1) among a set of grassland plants the abundance of soil decomposers in the plant rhizosphere is positively associated with plant N uptake from soil organic matter. To test this, we established grassland microcosms consisti…

Chromatin-associated RNA interference components contribute to transcriptional regulation in Drosophila

2009

RNA interference (RNAi) pathways have evolved as important modulators of gene expression that operate in the cytoplasm by degrading RNA target molecules through the activity of short (21-30 nucleotide) RNAs1-6. RNAi components have been reported to have a role in the nucleus, as they are involved in epigenetic regulation and heterochromatin formation(7-10). However, although RNAi-mediated post-transcriptional gene silencing is well documented, the mechanisms of RNAi-mediated transcriptional gene silencing and, in particular, the role of RNAi components in chromatin dynamics, especially in animal multicellular organisms, are elusive. Here we show that the key RNAi components Dicer 2 (DCR2) a…

Promoter architecture and transcriptional regulation of Abf1-dependent ribosomal protein genes inSaccharomyces cerevisiae

2016

In Saccharomyces cerevisiae, ribosomal protein gene (RPG) promoters display binding sites for either Rap1 or Abf1 transcription factors. Unlike Rap1-associated promoters, the small cohort of Abf1-dependent RPGs (Abf1-RPGs) has not been extensively investigated. We show that RPL3, RPL4B, RPP1A, RPS22B and RPS28A/B share a common promoter architecture, with an Abf1 site upstream of a conserved element matching the sequence recognized by Fhl1, a transcription factor which together with Ifh1 orchestrates Rap1-associated RPG regulation. Abf1 and Fhl1 promoter association was confirmed by ChIP and/or gel retardation assays. Mutational analysis revealed a more severe requirement of Abf1 than Fhl1 …

Vesiculated tuffs and associated features

1974

Vesiculated tuffs are tuffs that contain vesicles between the ash particles. Formation of the vesicles is the result of trapping of steam, the transporting agent of volcanic base surges, in wet, muddy or sticky ash deposited by the base surges. Vesiculated tuffs are described from various maars and tuff-rings in Europe (Iceland, France, Germany) and USA together with associated surface features such as: gravity flowage ripples, mud flow channels, current ripples, and current ridges. Other features described are: plastering of ash against obstacles and vesiculated accretionary lapilli, the latter containing vesicles in the outer layer. Vesiculated base surge deposits probably contained as mu…

Structural and Dynamical Complexities of Risk and Catastrophe Systems: an Approach by System Dynamics Modelling

2009

Risk and catastrophe are complex systems. Within the scope of this paper, we focus our attention on structural and dynamic complexities of catastrophes and on the possibility of modelling and simulating its double complexity with a formal and methodological framework: the General Systems Theory and System Dynamics modelling. Then we briefly propose a model of urban catastrophe related to a flood. After we propose some ways of research allowing exceeding the limits related to the modelling.