Search results for "complication"

showing 10 items of 2051 documents

Treatment and its side effects in ANCA-associated vasculitides - Study based on POLVAS registry data.

2020

Abstract Purpose The aim of this study is to present the treatment modalities and associated side effects in a Polish nation-wide ANCA-associated vasculitides (AAV) patients’ cohort. Materials and methods Retrospective analysis of patients diagnosed with AAV between 1990 and 2016, included in the POLVAS registry was performed. Standard descriptive statistic methods were used with an emphasis on the treatment modalities. Results There were 625 patients diagnosed with AAV included in this study: 417 cases of granulomatosis with polyangiitis (GPA; 66.7%), 106 cases of microscopic polyangiitis (MPA; 17.0%) and 102 cases of eosinophilic granulomatosis with polyangiitis (EGPA; 16.3%). The mean ag…

AdultMalemedicine.medical_specialtyCyclophosphamideDrug-Related Side Effects and Adverse ReactionsAzathioprineAnti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis03 medical and health sciences0302 clinical medicineMaintenance therapyInternal medicineAzathioprinemedicineHumansTreatment complications030212 general & internal medicineRegistriesAdverse effectCyclophosphamideGlucocorticoidsANCA associated vasculitisRetrospective Studiesbusiness.industryVasculitis registryGeneral MedicineMiddle Agedmedicine.diseasePrognosisSurvival RateMethotrexate030220 oncology & carcinogenesisCohortRituximabDrug Therapy CombinationFemalePolandMicroscopic polyangiitisGranulomatosis with polyangiitisbusinessRituximabVasculitis treatmentImmunosuppressive Agentsmedicine.drugFollow-Up StudiesAdvances in medical sciences
researchProduct

Cystic vestibular schwannoma: classification, management, and facial nerve outcomes.

2009

OBJECTIVE: Review of postoperative morbidity and facial nerve outcomes of cystic vestibular schwannoma (CVS) patients compared with solid vestibular schwannoma (SVS) patients and a proposal for a new CVS classification system. STUDY DESIGN: Retrospective review. SETTING: Tertiary care facility. PATIENTS: Ninety-six patients with surgically treated CVS (1998-2008). Outcomes were assessed in a subpopulation of 57 patients with greater than or equal to 1-year follow-up compared with 57 SVS patients. INTERVENTION: Fifty-six CVS patients underwent the enlarged translabyrinthine approach with transapical extension (Type I), and 1 patient underwent a transcochlear/transzygomatic approach. MAIN OUT…

AdultMalemedicine.medical_specialtyCystic vestibular schwannomaSchwannomaVestibular schwannomaPostoperative ComplicationsmedicineHumansCystCranial Nerve NeoplasmsFacial nerve outcomesAgedRetrospective StudiesAged 80 and overTranslabyrinthine approachbusiness.industryCystsAcoustic neuromaRetrospective cohort studyNeuroma AcousticMiddle AgedNeurovascular bundlemedicine.diseaseNeuromaFacial nerveMagnetic Resonance ImagingSensory SystemsSurgeryDissectionTreatment OutcomeOtorhinolaryngologyTranslabyrinthine approachFemaleNeurology (clinical)Facial Nerve DiseasesbusinessOtologic Surgical ProceduresFollow-Up StudiesOtologyneurotology : official publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology
researchProduct

DNA damage in leukocytes and serum nitrite concentration are negatively associated in type 1 diabetes.

2020

Abstract Chronic hyperglycaemia leads to DNA damage in diabetes and might be associated with nitrosative stress. In this study, we aimed at assessing the level of DNA strand breaks in leukocytes, serum nitrite and nitrate in patients with type 1 diabetes and healthy controls and associations of these parameters with diabetes-related outcomes in a prospective study. The level of DNA damage was determined in 71 patients with type 1 diabetes and 57 healthy controls by comet assay and scored with arbitrary units (AU). The chemiluminescence method was used to measure nitrite and nitrate. Clinical information and data on consumption of alcohol, physical activity and smoking were collected. Progre…

AdultMalemedicine.medical_specialtyDNA damageHealth Toxicology and MutagenesisArbitrary unit030204 cardiovascular system & hematologyToxicologyDiabetes Complications03 medical and health scienceschemistry.chemical_compound0302 clinical medicineInternal medicineDiabetes mellitusGeneticsmedicineLeukocytesHumansProspective StudiesNitriteProspective cohort studyGenetics (clinical)Nitrites030304 developmental biology0303 health sciencesType 1 diabetesbusiness.industrymedicine.diseaseComet assayEndocrinologyDiabetes Mellitus Type 1chemistryRelative riskFemaleComet AssaybusinessDNA DamageMutagenesis
researchProduct

Simple endoscopic decompression of cubital tunnel syndrome with the Agee system: anatomic study and first clinical results.

2010

BACKGROUND Simple decompression in ulnar nerve compression syndromes offers options for endoscopic applications. OBJECTIVE The authors present their initial experience with the Agee device. PATIENTS AND METHODS The monoportal endoscopic technique (Agee system) was evaluated on 10 cadaveric arms. Subsequently, 32 arms of 29 patients were operated on between January 2006 and March 2009. All patients presented with typical clinical signs and neurophysiologic studies. Long-term follow-up examinations were obtained in 27 of 32 arms. RESULTS In the cadaver study, the ulnar nerve was always correctly identified. No nerve damage occurred, and sufficient decompression of the ulnar nerve was always a…

AdultMalemedicine.medical_specialtyDecompressionCubital Tunnel SyndromePostoperative ComplicationsCadaverPreoperative CaremedicineCadaverElbowHumansUlnar nerve entrapmentUlnar nerveProspective cohort studyUlnar NerveAgedmedicine.diagnostic_testbusiness.industryDissectionSurgical woundEndoscopyMiddle Agedmedicine.diseaseDecompression SurgicalSurgeryEndoscopyTreatment OutcomePatient SatisfactionSurgeryFemaleNeurology (clinical)Cadaveric spasmbusinessNeurosurgery
researchProduct

Treatment of injuries to the inferior alveolar nerve after endodontic procedures.

1998

Overextension of filling material into the mandibular canal after root treatment in the lower jaw is a rare but serious complication. Mechanical compression, chemical neurotoxicity and local infection may cause irreversible nerve damage. A report on 11 patients with neurological complaints of the inferior alveolar nerve after endodontic treatment is summarised. The neurological findings are dominated by hypaesthesia and dysaesthesia. Half of the patients reported pain. Hyperaesthesia is found much more rarely. Nearly all the patients had a combination of one or more symptoms. Initial X-rays showed root filling material in the area of the mandibular canal. Nine cases were treated with apicec…

AdultMalemedicine.medical_specialtyDecompressionmedicine.medical_treatmentMandibular NerveDentistryMandibular canalInferior alveolar nerveApicectomyHypesthesiaRoot Canal Filling Materialsstomatognathic systemmedicineHumansParesthesiaGeneral DentistryENDODONTIC PROCEDURESbusiness.industryNerve Compression SyndromesApicoectomyNerve injuryMiddle AgedDecompression SurgicalSurgeryRoot Canal Therapystomatognathic diseasesmedicine.anatomical_structureApicoectomyTooth ExtractionNeuralgiaFemaleTrigeminal Nerve Injuriesmedicine.symptombusinessComplicationFollow-Up StudiesClinical oral investigations
researchProduct

Venous thromboembolism after oral and maxillofacial oncologic surgery: Report and analysis of 14 cases in Chinese population.

2016

Background Venous thromboembolism (VTE) including deep vein thrombosis (DVT) and pulmonary embolism (PE) is a leading cause of death in cancer patients. The aim of this study was to explore the potential risk factor of VTE in oral and maxillofacial oncological surgery. Material and Methods The data of patients who received operation in our institution were gathered in this retrospective study. A diagnosis of VTE was screened and confirmed by computer tomography angiography (CTA) of pulmonary artery or ultrasonography examination of lower extremity. Medical history and all perioperative details were analyzed. Results 14 patients were diagnosed as VTE, including 6 cases of PE, 7 cases of DVT,…

AdultMalemedicine.medical_specialtyDeep vein03 medical and health sciences0302 clinical medicinePostoperative ComplicationsAsian PeopleRisk FactorsMedicineHumansMedical historycardiovascular diseasesGeneral DentistryCause of deathAgedRetrospective StudiesMaxillary Neoplasmsbusiness.industryResearchRetrospective cohort study030206 dentistryPerioperativeVenous ThromboembolismMiddle Aged:CIENCIAS MÉDICAS [UNESCO]medicine.diseaseThrombosisSurgeryPulmonary embolismmedicine.anatomical_structure030228 respiratory systemOtorhinolaryngologyUNESCO::CIENCIAS MÉDICASOral and maxillofacial surgerySurgeryFemaleMouth NeoplasmsRadiologyFacial NeoplasmsOral SurgerybusinessMedicina oral, patologia oral y cirugia bucal
researchProduct

Prevalence of complications after the oral rehabilitation with implant-supported hybrid prostheses

2010

Objectives: Assess the main problems referred by the patients and observed by the professionals after the bucodental rehabilitation with an implant-supported hybrid prothesis. Patient and Methods: A retrospective study was carried out in which there were 43 patients included who were visited in the Department of Oral Surgery and Orofacial Implantology of University of Barcelona Dental School for one year. An oral rehabilitation with an implant-supported hybrid prosthesis was made to those patients. The following variables were registered: age, gender, number of inserted implants, type of implant and principal problems produced by the hybrid prosthesis. Results: The rehabilitation with an im…

AdultMalemedicine.medical_specialtyDental prosthesismedicine.medical_treatmentDentistryProsthesis DesignComplicacions quirúrgiquesProsthesisOral hygienePostoperative ComplicationsPrevalencemedicineMucositisHumansComplications of surgeryGeneral DentistryAgedRetrospective StudiesRehabilitationImplants dentalsbusiness.industryDental prosthesisDental implantsRetrospective cohort studyMiddle Aged:CIENCIAS MÉDICAS [UNESCO]medicine.diseasePròtesis dentalsSurgeryProthesisOtorhinolaryngologyUNESCO::CIENCIAS MÉDICASFemaleResearch-ArticleSurgeryDental Prosthesis Implant-SupportedImplantOral Surgerybusiness
researchProduct

Simultaneous Pancreas Kidney Transplantation Improves Cardiovascular Autonomic Neuropathy with Improved Valsalva Ratio as the Most Precocious Test

2020

Background. Simultaneous pancreas-kidney (SPK) transplantation is a proven option of treatment for patients with type 1 diabetes mellitus (T1DM) and related end-stage renal disease. There is discrepancy between the results of different studies about the impact of prolonged normalization of glucose metabolism achieved by SPK on the course of diabetic complications including severe forms of diabetic neuropathy. The objective of the study was to evaluate the prevalence of cardiovascular autonomic neuropathy (CAN) in patients undergoing SPK transplantation and its evolution 10 years after transplantation. Methods. Prospective study of 81 patients transplanted in a single center from year 2002 t…

AdultMalemedicine.medical_specialtyDiabetic neuropathyComplicationsArticle SubjectEndocrinology Diabetes and MetabolismSingle CenterAutonomic Nervous SystemDiseases of the endocrine glands. Clinical endocrinologyAssociationTECNOLOGIA ELECTRONICAEndocrinologyTrial/EpidemiologyDiabetic NeuropathiesInternal medicineDiabetes mellitusDiagnosismedicineAutonomic reflexRisk-FactorsHumansDiabetes-MellitusProspective StudiesMortalityProspective cohort studyInterventionsType 1 diabetesbusiness.industryGraft SurvivalMiddle Agedmedicine.diseaseRC648-665Kidney TransplantationTransplantationBlood pressureDiabetes Mellitus Type 1Treatment OutcomeDysfunctionCardiologyClinical StudyFemaleStatementPancreas TransplantationbusinessFollow-Up StudiesJournal of Diabetes Research
researchProduct

Postoperative pain therapy after lumbar disc surgery.

2000

Object. This study was undertaken to determine whether a special postoperative pain administration of tramadol and diclofenac provides any benefits in patients who underwent microsurgical lumbar discectomy.  Methods. The study consisted of 60 patients undergoing microsurgical lumbar discectomy. Patients were randomly divided into two groups based on the postoperative pain management: 1) Group A (n=30): no standardized pain therapy; these patients received on demand different analgesics and at variable dosages which were selected by the neurosurgeons; 2) Group B (n=30): standardized pain therapy with specific dosages of tramadol and diclofenac in regular time intervals during the first 48 ho…

AdultMalemedicine.medical_specialtyDiclofenacAnalgesicPainLumbar vertebraeDiclofenacPostoperative ComplicationsmedicineHumansHerniaIntervertebral DiscTramadolAgedPain MeasurementLumbar Vertebraemedicine.diagnostic_testbusiness.industryAnti-Inflammatory Agents Non-SteroidalInterventional radiologyMiddle Agedmedicine.diseaseSurgeryAnalgesics OpioidIntervertebral diskmedicine.anatomical_structureAnesthesiaSurgeryDrug Therapy CombinationFemaleNeurology (clinical)TramadolComplicationbusinessmedicine.drugDiskectomyActa neurochirurgica
researchProduct

Surgery during etanercept therapy in patients with rheumatoid arthritis: is it time to follow patient preferences?

2008

Tumor necrosis factor (TNF)-a inhibitors, such as etanercept and infliximab, improve symptoms and function in patients affected by rheumatoid arthritis (RA) [1, 2] and, therefore, are playing an increasing role in the management of this disease. However, interference with endogenous TNF-a signalling has been reported to alter both normal inflammatory responses in tissue healing and infection surveillance [2, 3]. To our knowledge, the rates of surgery in RA are decreasing. However, with the duration of antiTNF therapy, the number of patients under these agents having surgery will be increasing. These data raise the question of whether TNF-inhibitors can be safely used in RA patients who shou…

AdultMalemedicine.medical_specialtyDiseaseReceptors Tumor Necrosis FactorEtanerceptEtanerceptArthritis RheumatoidPostoperative ComplicationsInternal MedicinemedicineOutpatient clinicHumansElective surgeryWound Healingbusiness.industryContraindicationsAnti-Inflammatory Agents Non-SteroidalMiddle Agedmedicine.diseaseInfliximabSurgeryItalyPatient SatisfactionRheumatoid arthritisImmunoglobulin GSurgical Procedures OperativeCohortEmergency MedicineQuality of LifeMethotrexateFemalebusinessmedicine.drugInternal and emergency medicine
researchProduct