Search results for "complication"

showing 10 items of 2051 documents

β2-Adrenoceptors and GRK2 as Potential Biomarkers in Patients With Chronic Pulmonary Regurgitation

2019

Pulmonary regurgitation (PR) is a frequent complication after repair of congenital heart disease. Three different GRK isoforms (GRK2, GRK5, and GRK3) and two β-adrenoceptors (β1-AR and β2-AR) are present in peripheral blood mononuclear cells (PBMC) and their expression changes as a consequence of the hemodynamic and neurohumoral alterations that occur in some cardiovascular diseases. Therefore, they could be useful as biomarkers in PR. A prospective study was conducted to describe the expression (TaqMan Gene Expression Assays) of β-ARs and GRKs in PBMC isolated (Ficoll® gradient) from patients with severe PR before and after pulmonary valve replacement and establish if this expression corre…

0301 basic medicinemedicine.medical_specialtyHeart diseaseGRK2HemodynamicsPulmonary regurgitationright ventricleGastroenterologyAsymptomaticPeripheral blood mononuclear cell03 medical and health sciences0302 clinical medicinepulmonary regurgitationPulmonary Valve ReplacementInternal medicineGene expressionmedicinePharmacology (medical)Prospective cohort studyβ2-adrenoceptorCongenital heart diseaseOriginal ResearchPharmacologybusiness.industrylcsh:RM1-950medicine.diseasecongenital heart diseaselcsh:Therapeutics. Pharmacology030104 developmental biologyPulmonary valve replacement030220 oncology & carcinogenesispulmonary valve replacementRight ventriclemedicine.symptomComplicationbusinessFrontiers in Pharmacology
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Postoperative intestinal fistula in primary advanced ovarian cancer surgery

2021

Antoni Llueca,1– 3 Anna Serra,1– 3 Maria Teresa Climent,1,2 Karina Maiocchi,2,4 Alvaro Villarin,2,4 Katty Delgado,2,5 Josep Mari-Alexandre,6 Juan Gilabert-Estelles,6,7 Paula Carrasco,3 Blanca Segarra,8 Luis Gomez,2,4 Juan Jose Hidalgo,3 Javier Escrig,3 Manuel Laguna2,4 On behalf of the MUAPOS working group (Multidisciplinary Unit of Abdominal Pelvic Oncology Surgery1Department of Gynecology and Obstetrics, University General Hospital of Castellon, Castellón, Spain; 2Multidisciplinary Unit of Abdominal Pelvic Oncology Surgery (MUAPOS), University General Hospital of Castellon, Castellón, Spain; 3Department of Medicine, University Jaume I (UJI), Caste…

0301 basic medicinemedicine.medical_specialtyMultivariate analysiscomplicationsFistulalcsh:RC254-28203 medical and health sciences0302 clinical medicineintestinal fistulaMedicineIn patientintestinal leakageOriginal ResearchAdvanced ovarian canceradvanced ovarian cancer surgerybusiness.industrymedicine.diseaseDebulkinglcsh:Neoplasms. Tumors. Oncology. Including cancer and carcinogensSurgeryBowel obstruction030104 developmental biologyOncologyCancer Management and Research030220 oncology & carcinogenesisConventional PCIPeritoneal Cancer Indexbusiness
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Potential risks to offspring of intrauterine exposure to maternal age-related obstetric complications

2016

Several hypotheses have been proposed to explain the negative effects of delayed motherhood on an offspring’s morbidity later in life. However, these hypotheses are not supported by clinical and epidemiological evidence. Because advanced maternal age is associated with increased risk of obstetric complications, the aim of the present study was to ascertain whether the negative effects on offspring of intrauterine exposure to maternal age-related obstetric complications may explain the reported negative effects of delayed motherhood on offspring. To this end, a literature search was performed to identify relevant publications up to March 2016 on PubMed; references cited in relevant articles …

0301 basic medicinemedicine.medical_specialtyOffspringmedia_common.quotation_subjectFertilityReproductive technologyBiologyMaternal PhysiologyEpigenesis Genetic03 medical and health sciences0302 clinical medicineEndocrinologyPregnancyRisk FactorsGeneticsmedicineHumansFertility preservationAdvanced maternal ageMolecular Biologymedia_commonPregnancy030219 obstetrics & reproductive medicineMaternal TransmissionObstetricsAge FactorsPregnancy Outcomemedicine.diseasePregnancy Complications030104 developmental biologyReproductive MedicinePrenatal Exposure Delayed EffectsFemaleAnimal Science and ZoologyMaternal AgeDevelopmental BiologyBiotechnologyReproduction, Fertility and Development
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Presence of Trichomonas spp. in oral ulcerations of a patient with kidney transplant. A case report

2020

Mucosal ulcerations are an oral complication that can often affect kidney transplant patients, mostly due to the effect of immunosuppression. It has been frequently reported drug-induced ulceration or lymphoproliferative disorders with buccal manifestations however, some unusual disorders should also be considered, such as fungal infections, viruses, as well as opportunistic infection by other microorganisms. Determining the etiology and differential diagnose from other causes of mouth ulcers is very important for the adequate treatment of said lesion. Dental health of patients should also be taken into the account prior to the transplant surgery, since periodontal pockets are the main nich…

0301 basic medicinemedicine.medical_specialtyOpportunistic infectionmedicine.medical_treatmentTrichomonasORAL MUCOSALymphoproliferative disordersCase ReportKIDNEY TRANSPLANTDental plaque03 medical and health sciences0302 clinical medicine//purl.org/becyt/ford/3.2 [https]medicineOral mucosaPROTOZOANMouth ulcersGeneral DentistryOral ComplicationUNESCO:CIENCIAS MÉDICASIMMUNOSUPPRESSIONbiologybusiness.industryImmunosuppression030206 dentistrymedicine.diseasebiology.organism_classificationDermatologystomatognathic diseases030104 developmental biologymedicine.anatomical_structureOdontostomatology for the Disabled or Special Patients//purl.org/becyt/ford/3 [https]medicine.symptombusinessBUCCAL LESION
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Body Mass Index in Patients Treated with Cabozantinib for Advanced Renal Cell Carcinoma: A New Prognostic Factor?

2021

We analyzed the clinical and pathological features of renal cell carcinoma (RCC) patients treated with cabozantinib stratified by body mass index (BMI). We retrospectively collected data from 16 worldwide centers involved in the treatment of RCC. Overall survival (OS) and progression-free survival (PFS) were analyzed using Kaplan&ndash

0301 basic medicinemedicine.medical_specialtyPrognostic factorobesityrenal cell carcinomaMultivariate analysisCabozantinibPrognosiClinical Biochemistrybody mass indexurologic and male genital diseasesGastroenterologyArticle03 medical and health scienceschemistry.chemical_compound0302 clinical medicineRenal cell carcinomacabozantinibInternal medicinemedicineOverall survivalIn patientneoplasmsPathologicallcsh:R5-920real-world databusiness.industrybody mass index; cabozantinib; obesity; prognosis; real-world data; renal cell carcinoma; targeted therapymedicine.diseasetargeted therapyfemale genital diseases and pregnancy complications030104 developmental biologychemistry030220 oncology & carcinogenesisprognosislcsh:Medicine (General)businessBody mass indexDiagnostics
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Successful management of a cerebral abscess secondary to chronic cholesteatoma caused by Prevotella melaninogenica and Peptococcus anaerobius – A cas…

2016

Abstract Cerebral abscess following cholesteatomatous otomastoiditis is a life-threatening complication and poses diagnostic and therapeutic challenges. We report a case of life-threatening cerebritis and cerebral abscess due to a collection of pus from an aerobic super infections occurring months after the apparent resolution of an otogenic brain abscess in a 67-year-old immunocompetent Italian female. Two gram-positive anaerobic pathogens were isolated during secondary neurosurgical procedures and antibiotic treatment was adopted to resolve the complications. Another objective of this study was to review the literature on gram-positive anaerobic pathogens and brain abscess complications i…

0301 basic medicinemedicine.medical_specialtySettore MED/17 - Malattie InfettiveFistula030106 microbiologylcsh:Surgerylcsh:RC346-429Surgery; Neurology (clinical)Prevotella melaninogenica03 medical and health sciences0302 clinical medicineMedicineAbscessBrain abscesslcsh:Neurology. Diseases of the nervous systembusiness.industrySettore MED/27 - NeurochirurgiaCholesteatomalcsh:RD1-811medicine.diseasebacterial infections and mycosesSurgeryInfectious disease (medical specialty)CerebritisSurgeryNeurology (clinical)medicine.symptombusinessComplication030217 neurology & neurosurgeryInterdisciplinary Neurosurgery
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Factors Associated With Weight Gain in People Treated With Dolutegravir.

2020

AbstractBackgroundAn unexpected excess in weight gain has recently been reported in the course of dolutegravir (DTG) treatment. The aim of the present study was to investigate whether weight gain differs among different DTG-containing regimens.MethodsAdult naïve and experienced people with HIV (PWH) initiating DTG-based antiretroviral therapy (ART) between July 2014 and December 2019 in the Surveillance Cohort Long-Term Toxicity Antiretrovirals (SCOLTA) prospective cohort were included. We used an adjusted general linear model to compare weight change among backbone groups and a Cox proportional hazard regression model to calculate hazard ratios (HRs) and 95% confidence intervals (CIs) for …

0301 basic medicinemedicine.medical_specialtyWeight gain.HIV metabolic complications030106 microbiologyHIV metabolic complicationTDFEmtricitabineTenofovir alafenamidedolutegravir HIV metabolic complications TAF TDF weight gain.03 medical and health scienceschemistry.chemical_compound0302 clinical medicineAbacavirInternal medicinemedicineMajor Article030212 general & internal medicinebusiness.industryWeight changeLamivudineweight gaindolutegravirInfectious DiseasesAcademicSubjects/MED00290OncologychemistryTAFRilpivirineDolutegravirmedicine.symptombusinessWeight gainmedicine.drugOpen forum infectious diseases
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Complication of endoscopic tattooing: a case report of covered perforation

2016

Aim Laparoscopy is considered a good approach in treatment of colorectal neoplastic diseases; the endoscopic tattooing is then recommended (Evidence Level III and grade of recommendation A) to mark a lesion or a polypectomy site for intraoperative identification. We describe the case of perforation after tattoing treated conservatively. Case report 63 years old woman, underwent colonoscopy for lipoma tattooing with India ink SPOT® solution kit and saline test. Immediately after the procedure the patient has been referred the appearance of colic epi-mesogastric pain and fever; Computed Tomography (CT) without MDC identified an irregular thickening of transverse colon with some microbubbles c…

0301 basic medicinemedicine.medical_specialtymedicine.medical_treatmentPerforation (oil well)ColonoscopyPeritonitisBacteremiaClinical Practice03 medical and health sciences0302 clinical medicineEnteral NutritionmedicineHumansLaparoscopyColoring AgentsPerforationmedicine.diagnostic_testTattooingbusiness.industryTransverse colonEndoscopyColonoscopyMiddle Agedmedicine.diseaseEndoscopy; Perforation; Surgery; Tattoing; SurgeryPolypectomyCarbonSurgeryEndoscopyAnti-Bacterial AgentsTattoing030104 developmental biologyTreatment OutcomeIntestinal Perforation030220 oncology & carcinogenesisSurgeryFemaleLipomabusinessComplicationColorectal NeoplasmsTomography X-Ray Computed
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Factors associated with nocturia-related quality of life in men with lower urinary tract symptoms and treated with tamsulosin oral controlled absorpt…

2020

Nocturia impairs quality of life (QoL). We have performed a non-interventional study in which men with lower urinary tract symptoms (LUTS) were treated for at least 3 months with tamsulosin oral controlled absorption system (0.4 mg q.d.). Other than observing efficacy and tolerability of this drug formulation, the study was designed to explore the relative roles of number of nocturia episodes and of non-urological causes of nocturia on nocturia-related QoL at baseline and treatment-associated changes thereof. The study enrolled 5775 men seeking treatment of their LUTS. Tamsulosin improved LUTS, e.g. International Prostate Symptom Score from 19.5 +/- 5.9 to 10.1 +/- 4.9 (means +/- SD). This …

0301 basic medicinemedicine.medical_specialtyurologic and male genital diseases03 medical and health sciences0302 clinical medicineQuality of lifeLower urinary tract symptomsTamsulosinInternal medicinemedicineNocturiaPharmacology (medical)Original ResearchPharmacologyHeart Failurebusiness.industrylcsh:RM1-950DiabetesSleep apneamedicine.diseasehumanitiesfemale genital diseases and pregnancy complications030104 developmental biologylcsh:Therapeutics. PharmacologyTolerability030220 oncology & carcinogenesisHeart failureQuality of LifeInternational Prostate Symptom ScoreNocturiamedicine.symptombusinessMale Lower Urinary Tract Symptomsmedicine.drug
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Glikozes transportieru un slāpekļa oksīda produkcijas izmaiņas cukura diabēta komplikāciju patoģenēzē un to farmakoloģiskās korekcijas iespējas

2014

Elektroniskā versija nesatur pielikumus

14-dihidropiridīnimildronātsmildronateMedical biochemistrydiabetic complicationsMedicīna un farmācijaMedicīniskā bioķīmijacukura diabēta komplikācijasVeselības aprūpeMedicīna14-dihydropyridines
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