Search results for "composites"

showing 10 items of 1905 documents

Computational simulations on the binding and reactivity of a nitrile inhibitor of the SARS-CoV-2 main protease.

2021

We present a detailed computational analysis of the binding mode and reactivity of the novel oral inhibitor PF-07321332 developed against the SARS-CoV-2 3CL protease. Alchemical free energy calculations suggest that positions P3 and P4 could be susceptible to improvement in order to get a larger binding strength. QM/MM simulations unveil the reaction mechanism for covalent inhibition, showing that the nitrile warhead facilitates the recruitment of a water molecule for the proton transfer step.

Reaction mechanismNitrileLactamsProlineStereochemistrymedicine.medical_treatmentMolecular Dynamics SimulationCatalysischemistry.chemical_compoundMolecular dynamicsLeucineCatalytic DomainNitrilesMaterials ChemistrymedicineMoleculeHumansReactivity (chemistry)Protease InhibitorsBinding siteCoronavirus 3C ProteasesProteaseBinding SitesSARS-CoV-2Metals and AlloysCOVID-19General ChemistrySurfaces Coatings and FilmsElectronic Optical and Magnetic MaterialschemistryCovalent bondCeramics and CompositesQuantum TheoryThermodynamicsChemical communications (Cambridge, England)
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Chain-extending of Hydroxytelechelic Polybutadiene: Synthesis and Characterization

2010

Extension of hydroxytelechelic polybutadiene oligomers ( 3200 g/mol) is performed in mild conditions, in order to avoid backbone modifications, using succinic anhydride or methylenedicyclohexyl diisocyanate. The two routes present significative extension of the initial oligomers. Extension through the anhydride route, in the presence of DCC and DMAP, leads to new hydroxytelechelic oligomers ( 8000 g/mol). Extension through the diisocyanate route, catalyzed by DBTL at 65°C leads to hydroxytelechelic oligomers of higher average molecular weight ( 20000 g/mol). New materials are characterized by FTIR/1H-NMR and changes in their Tg according to , are discussed. The influence of reaction time on…

Reaction mechanismTelechelic polymerPolymers and PlasticsSuccinic anhydrideGeneral ChemistryOligomerchemistry.chemical_compoundPolybutadienechemistryPolymer chemistryMaterials ChemistryCeramics and CompositesMolar mass distributionOrganic chemistryGlass transitionMacromoleculeJournal of Macromolecular Science, Part A
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A chemical and electrochemical multivalent memory made from FeNi3-graphene nanocomposites

2014

FeNi3-graphene nanocomposites present in acetonitrile solutions a redox couple with an electrochemical hysteresis of 2.4 V between the oxidation and the reduction maxima. In view of the high energy required for the reverse transitions, they are here proposed as chemical multilevel memories: permanent, after drying, or erasable in electrolytes, respectively. Keywords: FeNi3-graphene nanocomposites, Voltammetry, Coulovoltammetry, Redox couple, Redox hysteresis

Redox hysteresisHigh energyMaterials scienceInorganic chemistryRedox coupleFeNi3-graphene nanocompositesElectrolyteElectrochemistryRedoxlcsh:ChemistryHysteresischemistry.chemical_compoundlcsh:Industrial electrochemistrylcsh:QD1-999Graphene nanocompositeschemistryChemical engineeringCoulovoltammetryElectrochemistryVoltammetryAcetonitrileVoltammetrylcsh:TP250-261Electrochemistry Communications
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Mixed finite elements for nonlocal elastic multilayered composite plate refined theories

2020

Abstract A novel mixed finite element formulation for the layerwise analysis of nonlocal multilayered composite plates is presented. The finite elements are formulated starting from the weak form of a set of governing equations for the laminate layers that were deduced via the Reissner Mixed Variational Theorem. The primary variables, namely displacements and out-of-plane stresses, are expressed at layer level as through-the-thickness expansions of suitable selected functions with coefficients approximated by the finite element scheme. The through-the-thickness expansion order is considered as a free parameter. This way, finite elements for different refined higher order plate theories can …

Refined plate theorieQuadrilateralMathematical analysisReissner Mixed Variational Theorem02 engineering and technology021001 nanoscience & nanotechnologyFinite element methodSet (abstract data type)Mixed finite element020303 mechanical engineering & transports0203 mechanical engineeringNonlocal elasticityComposite platePlate theoryCeramics and CompositesOrder (group theory)Settore ING-IND/04 - Costruzioni E Strutture Aerospaziali0210 nano-technologyLaminated compositesCivil and Structural EngineeringFree parameterMathematicsVariable (mathematics)Composite Structures
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Interaction of oxygen with Mo(100), Mo(110), and Mo(111) surfaces. RHEED and AES analyses of the molybdenum oxide nucleation and growth

1991

Abstract A study of the nucleation and growth of MoO 3 generated by interaction of oxygen with Mo(100), Mo(110), and Mo(111) single crystalline surfaces is investigated at high oxygen pressure (10 4 Pa) and low temperature (620 to 820 K). The results of RHEED and AES analyses prove that under these oxidation conditions, MoO 3 nucleates directly from the metal without intermediate formation of MoO 2 or nonstoichiometric molybdenum oxide such as Mo 4 O 11 . The structure and orientation of MoO 3 nuclei are characterized in relation with the parent molybdenum surface. On the Mo(110) and Mo(111) surfaces, which are faceting, the nucleation and growth of MoO 3 takes place by successive structura…

Reflection high-energy electron diffractionDiffusionNucleationchemistry.chemical_elementCondensed Matter PhysicsEpitaxyOxygenElectronic Optical and Magnetic MaterialsInorganic ChemistryFacetingMetalCrystallographychemistryMolybdenumvisual_artMaterials ChemistryCeramics and Compositesvisual_art.visual_art_mediumPhysical and Theoretical ChemistryJournal of Solid State Chemistry
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A preliminary comparison between finite element and meshless simulations of extrusion

2009

In this paper the extrusion process of a cross-shaped profile was investigated. In particular, the study was focused on the distortion of extruding profiles when the workpiece and die axis are not aligned. The process was simulated using the finite element method (FEM) and the natural element method (NEM), both implemented in an updated-Lagrangian formulation, in order to avoid the burden associated with the description of free surfaces in ALE or Eulerian formulations. Furthermore, an experimental equipment was developed in order to obtain reliable data in terms of deformed entity, required process load and calculated pressure. At the end, a comparison between the numerical predictions and …

Regularized meshless methodMaterials scienceFinite element limit analysisbusiness.industryMetals and AlloysMixed finite element methodStructural engineeringBoundary knot methodIndustrial and Manufacturing EngineeringFinite element methodDiscrete element methodComputer Science Applicationsextrusion modellingModeling and SimulationCeramics and CompositesSmoothed finite element methodmeshless methodbusinessSettore ING-IND/16 - Tecnologie E Sistemi Di LavorazioneExtended finite element methodJournal of Materials Processing Technology
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Influence of some relevant process parameters on the dimensional accuracy in incremental forming: a numerical and experimental investigation

2004

Abstract As known, incremental forming is a flexible and innovative sheet metal forming process which allows complex shape shells forming without the need for any die. For these reasons, incremental forming is nowadays suggested for rapid prototyping and customised products. The present paper is focused on material formability in incremental forming and, in particular, on the evaluation and compensation of elastic springback. The latter significantly modifies the imposed shape. For this purpose, a deeper assessment of the process was developed following three different approaches. First of all, a wide experimental investigation on the influence of some relevant process parameters was develo…

Reverse engineeringFEMEngineeringbusiness.product_categorybusiness.industryIncremental formingDesign toolMetals and AlloysProcess (computing)Forming processesStructural engineeringGeometrical accuracycomputer.software_genreIndustrial and Manufacturing EngineeringFinite element methodComputer Science ApplicationsModeling and Simulationvisual_artCeramics and Compositesvisual_art.visual_art_mediumFormabilityDie (manufacturing)Sheet metalbusinesscomputerJournal of Materials Processing Technology
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X-ray powder diffraction study of monoclinic V4+-ZrO2 solid solutions obtained from gels

2003

Abstract Rietveld refinement of six monoclinic V x Zr 1− x O 2 solid solutions, with x =0, 0.01, 0.02, 0.05, 0.075 and 0.1, prepared by heating dried gel precursors at 1300°C in air atmosphere, has been characterized using X-ray powder diffractometer data. The present results confirm that crystal structure of these solid solutions contain V 4+ (Zr 4+ ) cations surrounded by seven oxygens, four at a distance between 2.13 and 2.28 A (referred as to O(2) in the tetrahedrally coordinated oxygens) and other three at a distance between 2.03 and 2.20 A (denoted as O(1) in the triangularly coordinated oxygens). The trends in the lattice parameter variation of V x Zr 1− x O 2 solid solutions specime…

Rietveld refinementChemistryVanadiumchemistry.chemical_elementCrystal structureCondensed Matter PhysicsElectronic Optical and Magnetic MaterialsInorganic ChemistryCrystallographyLattice constantPowder DiffractometerMaterials ChemistryCeramics and CompositesPhysical and Theoretical ChemistryPowder diffractionMonoclinic crystal systemSolid solutionJournal of Solid State Chemistry
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Cerium effect on the phase structure, phase stability and redox properties of Ce-doped strontium ferrates

2006

Nanostructured perovskite-type Sr1−aCeaFeO3−x, (0⩽a<0.15) powders have been prepared by citrate–nitrate smoldering auto-combustion. Their phase structure and stability, surface and morphological properties, reduction behavior and interaction with oxygen have been investigated by X-ray Powder Diffraction combined with Rietveld Analysis, 57Fe Mossbauer and X-ray Photoelectron Spectroscopies, N2-adsorption method, Temperature Programmed Reduction and Oxidation experiments. Our results reveal that citrate–nitrate auto-combustion method is effective in obtaining single phase Sr1−aCeaFeO3−x. The Sr1−aCeaFeO3−x structure is cubic only for a⩾0.06, while for a<0.06 remains tetragonal. Moreover, for …

Rietveld refinementInorganic chemistrychemistry.chemical_elementCondensed Matter PhysicsElectronic Optical and Magnetic MaterialsInorganic ChemistryCeriumTetragonal crystal systemchemistryPhase (matter)X-ray crystallographyMaterials ChemistryCeramics and CompositesPhysical chemistryPhysical and Theoretical ChemistryTemperature-programmed reductionPowder diffractionPerovskite (structure)
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Structural and morphological properties of Co-La catalysts supported on alumina/lanthana for hydrocarbons oxidation

2004

Abstract Two Al 2 O 3 (24 wt%)–La 2 O 3 (76 wt%) supported Co–La oxides with Co loading 4 wt% and different La content (1 and 9 wt%) were prepared by co-impregnation of the support, the aluminum–lanthanum oxide, with cobalt and lanthanum nitrates in aqueous solution and successive calcination at 800 °C for 4 h. The alumina–lanthana was synthesized by the sol–gel method. The samples were characterized by X-ray diffraction (XRD) and Rietveld refinement in order to identify the crystalline phases and their relative weight. H 2 -TPR (Temperature Programmed Reduction) experiments were recorded with the aim to identify the different Co phases present. Co 3 O 4 and LaCoO 3 were formed for La loadi…

Rietveld refinementPEROVSKITEInorganic chemistryOxidechemistry.chemical_elementCondensed Matter PhysicsElectronic Optical and Magnetic Materialslaw.inventionCatalysischemistry.chemical_compoundCOMBUSTIONchemistrylawLACOO3Materials ChemistryCeramics and CompositesLanthanumCalcinationAtomic ratioTemperature-programmed reductionCobalt
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