Search results for "computed tomography"

showing 10 items of 713 documents

Prediction of bone mechanical properties using QUS and pQCT: study of the human distal radius.

2007

Abstract The objective was to compare the prediction of bone mechanical properties provided by axial transmission to that provided by peripheral quantitative computed tomography (pQCT) at the distal radius. The distal radius is the location for Colles’ fractures, a common osteoporosis related trauma situation. Measurements of the radial speed of sound were performed using three axial transmission devices: a commercial device (Sunlight Omnisense, 1.25 MHz), a bi-directional axial transmission prototype (1 MHz), both measuring the velocity of the first arriving signal (FAS), and a low frequency (200 kHz) device, measuring the velocity of a slower wave. Co-localized pQCT measurements of bone m…

MaleMaterials scienceOsteoporosisBiomedical EngineeringBiophysicsModulusYoung's modulusIn Vitro TechniquesBone and Bonessymbols.namesakeImaging Three-DimensionalmedicineHumansQuantitative computed tomographyAgedUltrasonographyBone mineralAged 80 and overmedicine.diagnostic_testbusiness.industryUltrasoundStructural engineeringRadiusMiddle Agedmedicine.diseaseElasticityBiomechanical PhenomenaRadiussymbolsFemalebusinessTomography X-Ray ComputedQuasistatic processBiomedical engineeringMedical engineeringphysics
researchProduct

Quantitative assessment and localization of the hollowing of the temple after craniectomy and cranioplasty–The frontozygomatic shadow

2021

Background After cranioplasty, in many cases a not negligible soft tissue defect remains in the temporozygomatical area, also referred to as a hollowing defect of the temple. Objective To assess the precise localization and volume of the hollowing defect, to optimize future cranioplasties. Methods CT data of patients who received craniectomy and conventional CAD cranioplasty in our institution between 2012 and 2018 were analyzed. CT datasets prior to craniectomy and after cranioplasty were subtracted to quantify the volume and localization of the defect. Results Out of 91 patients, 21 had suitable datasets. Five cases had good cosmetic results with no defect visible, 16 patients had an app…

MaleMedical Implantsmedicine.medical_treatmentHealth Care ProvidersComputed tomographyNervous System ProceduresQuantitative assessmentMedicine and Health SciencesMedical PersonnelMusculoskeletal SystemMultidisciplinarymedicine.diagnostic_testQRSoft tissueMiddle AgedBuilt StructuresCranioplastyProfessionsmedicine.anatomical_structureTreatment OutcomeMedicineSuperior temporal lineEngineering and TechnologyFemaleAnatomyPlastic Surgery and Reconstructive TechniquesResearch ArticleBiotechnologyAdultmedicine.medical_specialtyDecompressive CraniectomyStructural EngineeringSoft TissuesScienceSurgical and Invasive Medical ProceduresBioengineeringTemporal MuscleZygomatic processTemporal muscleCranioplastyTime-to-TreatmentPhysiciansmedicineHumansSkeletonAgedRetrospective StudiesSurgeonsbusiness.industrySkullBiology and Life SciencesPlastic Surgery ProceduresSurgeryHealth CareSkullBiological TissuePeople and PlacesMedical Devices and EquipmentPopulation GroupingsbusinessTomography X-Ray ComputedHeadPLoS ONE
researchProduct

Evaluation of demineralized bone and bone transplantsin vitroandin vivowith cone beam computed tomography imaging

2010

The objective of this study was to determine the ability of two flat panel cone beam CT (CBCT) devices to identify demineralized bone and bone transplants in vivo and in vitro.Datasets from patients with autologous bone grafts (n = 9, KaVo 3DeXam (KaVo, Biberach, Germany); n = 38, Accuitomo 40 (Morita, Osaka, Japan)) were retrospectively evaluated. Demineralized and non-demineralized porcine cancellous bone blocks were examined with the two CBCT devices. A SawBone skull (Pacific Research Laboratories, Vashon, WA) was used as a positioning tool for the bone blocks. Descriptive evaluation and image quality assessment were conducted on the KaVo 3DeXam data (voxel size 0.3 mm) using the OsiriX …

MaleModels AnatomicCone beam computed tomographySwineDentistryBone and BonesBone remodelingIn vivoImage Processing Computer-AssistedAnimalsHumansMedicineRadiology Nuclear Medicine and imagingGeneral DentistryEdetic AcidCone beam ctAgedChelating AgentsRetrospective StudiesCryopreservationBone Demineralization TechniqueBone TransplantationAnatomy Cross-SectionalOrthognathic Surgical Proceduresbusiness.industryResearchGeneral MedicineCone-Beam Computed TomographyMiddle AgedRadiographic Image EnhancementSkullmedicine.anatomical_structureOtorhinolaryngologyBone Demineralization TechniqueFemaleBone RemodelingDemineralized bonebusinessNuclear medicineCancellous boneDentomaxillofacial Radiology
researchProduct

Three-Dimensional Reconstruction of the Bony Nasolacrimal Canal by Automated Segmentation of Computed Tomography Images.

2016

Objective To apply a fully automated method to quantify the 3D structure of the bony nasolacrimal canal (NLC) from CT scans whereby the size and main morphometric characteristics of the canal can be determined. Design Cross-sectional study. Subjects 36 eyes of 18 healthy individuals. Methods Using software designed to detect the boundaries of the NLC on CT images, 36 NLC reconstructions were prepared. These reconstructions were then used to calculate NLC volume. The NLC axis in each case was determined according to a polygonal model and to 2nd, 3rd and 4th degree polynomials. From these models, NLC sectional areas and length were determined. For each variable, descriptive statistics and nor…

MaleModels AnatomicCritical Care and Emergency Medicinelcsh:MedicineComputed tomographyPolynomialsDiagnostic RadiologyNormality test0302 clinical medicineMedicine and Health SciencesSegmentationDegree of a polynomiallcsh:ScienceTomographyMusculoskeletal SystemTrauma MedicineMathematicsMultidisciplinaryNasolacrimal ductmedicine.diagnostic_testRadiology and ImagingAnatomyMiddle Agedmedicine.anatomical_structureSurgery Computer-AssistedPhysical SciencesNasolacrimal canalFemaleAnatomyResearch ArticleAdultComputer and Information SciencesImaging TechniquesTrauma SurgeryAutomated segmentationNeuroimagingSurgical and Invasive Medical ProceduresResearch and Analysis MethodsBone and BonesComputer Software03 medical and health sciencesImaging Three-DimensionalDiagnostic MedicinemedicineHumansSkeletonAgedMorphometrySkulllcsh:RBiology and Life SciencesComputing MethodsComputed Axial TomographyCross-Sectional StudiesAlgebra030221 ophthalmology & optometrylcsh:QTomography X-Ray ComputedNasolacrimal DuctMathematics030217 neurology & neurosurgeryNeuroscienceBiomedical engineeringVolume (compression)PLoS ONE
researchProduct

Association between third molar agenesis and craniofacial structure development

2015

Introduction The aim of this investigation was to study the relationship between third molar agenesis—including the number of ageneses—and craniofacial structure growth. Methods We reviewed 305 clinical histories of patients treated at the Orthodontics Unit of the Faculty of Medicine and Dentistry at the University of Valencia in Spain. This included radiographic records of optimal quality. Of these, 40 patients who had agenesis of at least 1 third molar were included in the study group. A control group was formed with another 40 patients with all 4 third molars present. For both groups, a further criterion for inclusion was cone-beam computed tomography records. The cephalometric analysis …

MaleMolarCephalometric analysisAdolescentCephalometryDentistryOrthodonticsMandibleAnodontiaImaging Three-DimensionalMaxillaHumansMedicineNasal BoneGonial angleCraniofacialMaxillofacial DevelopmentAnodontiaSkull BaseOrthodonticsPalatebusiness.industryVertical DimensionCone-Beam Computed TomographyCraniometrymedicine.diseaseAgenesisMaxillaFemaleMolar ThirdbusinessAmerican Journal of Orthodontics and Dentofacial Orthopedics
researchProduct

Peptide Receptor Radionuclide Therapy Combined With Chemotherapy in Patients With Neuroendocrine Tumors

2019

Combinations of therapies may enhance therapeutic effects without significantly increasing the incidence of adverse events. However, there are few data regarding survival after concomitant chemotherapy and peptide receptor radionuclide therapy (PRRT) with [Lu]Lu-octreotate in patients with neuroendocrine tumors (NETs). Thus, we explored the outcome of this combination of therapies.Fifteen patients with somatostatin receptor-positive, rapidly progressive G2/G3 NETs during chemotherapy or PRRT alone from 2 German cancer centers were included in the retrospective analysis. The patients received a combination of PRRT and chemotherapy with temozolomide (n = 3) or temozolomide plus capecitabine (…

MaleOncologyAntimetabolites Antineoplasticmedicine.medical_specialtyPeptide receptormedicine.medical_treatmentNeuroendocrine tumorsOctreotide030218 nuclear medicine & medical imaging03 medical and health sciences0302 clinical medicinePositron Emission Tomography Computed TomographyInternal medicineOrganometallic CompoundsTemozolomidemedicineHumansRadiology Nuclear Medicine and imagingAdverse effectCapecitabineAgedChemotherapybusiness.industryIncidence (epidemiology)Therapeutic effectChemoradiotherapyGeneral MedicineMiddle Agedmedicine.diseaseNeuroendocrine Tumors030220 oncology & carcinogenesisConcomitantRadionuclide therapyFemaleRadiopharmaceuticalsbusinessClinical Nuclear Medicine
researchProduct

Focal or whole-gland salvage prostate brachytherapy with iodine seeds with or without a rectal spacer for postradiotherapy local failure: How best to…

2016

International audience; PURPOSE: Salvage prostate permanent implant (sPPI) for postradiation local failure provides high rates of biochemical control. The cumulative dose delivered to the prostate and the rectum is still unknown. METHODS AND MATERIALS: We reviewed the postimplant CT-based dosimetry of 18 selected patients who underwent sPPI with I-125 seeds for isolated biopsy-proven local failure several years after external beam radiation therapy. Ten patients had whole-prostate sPPI, and 8 patients had multiparametric MRI-based focal sPPI. In 8 patients, hyaluronic acid (HA) gel was injected into the prostate rectum space. RESULTS: The median cumulative biological effective dose after EB…

MaleOrgans at Risk[SDV.IB.IMA]Life Sciences [q-bio]/Bioengineering/Imagingmedicine.medical_treatmentBrachytherapySalvage therapyRecommendationsAlpha/Beta030218 nuclear medicine & medical imaging[ SDV.CAN ] Life Sciences [q-bio]/Cancer[ SDV.IB.MN ] Life Sciences [q-bio]/Bioengineering/Nuclear medicineIodine RadioisotopesBiologically effective doseProstate cancer0302 clinical medicineProstatePositron Emission Tomography Computed Tomography[ SDV.IB ] Life Sciences [q-bio]/BioengineeringHyaluronic Acid[ SDV.IB.IMA ] Life Sciences [q-bio]/Bioengineering/ImagingProstate cancerCumulative doseCancer RecurrencesRadiotherapy DosageMenLow dose rateMiddle AgedImplantation3. Good healthmedicine.anatomical_structureOncology030220 oncology & carcinogenesis[SDV.IB]Life Sciences [q-bio]/BioengineeringLocal failureProstate brachytherapymedicine.medical_specialtyBrachytherapyRectum[SDV.CAN]Life Sciences [q-bio]/Cancer[SDV.IB.MN]Life Sciences [q-bio]/Bioengineering/Nuclear medicineRadiation Dosage03 medical and health sciencesPermanent BrachytherapymedicineHumansProctitisRadiology Nuclear Medicine and imagingRadiation InjuriesProctitisAgedSalvage TherapySalvage brachytherapyRadiotherapybusiness.industryRadiotherapy Planning Computer-AssistedCarcinomaRectumProstatic Neoplasmsmedicine.diseaseRadiation-TherapySurgeryNeoplasm Recurrence LocalTomography X-Ray ComputedNuclear medicinebusinessGels
researchProduct

SEMI-AUTOMATIC VOLUMETRIC SEGMENTATION OF THE UPPER AIRWAYS IN PATIENTS WITH PIERRE ROBIN SEQUENCE

2014

Pierre Robin malformation is a rare craniofacial dysmorphism whose pathogenesis is multifactorial. Although there is some agreement in non-invasive treatment in less severe cases, the dispute is still open on cases with severe respiratory impairment. We present a semi-automatic novel diagnostic tool for calculating upper airway volume, in order to eventually address surgery in patients with Pierre Robin Sequence (PRS). Multidetector CT datasets of two patients and two controls were tested to assess the proposed method for ROI segmentation, upper airway volume computation and three-dimensional reconstructions. The experimental results show an irregular pattern and a severely reduced cross-s…

MalePathologymedicine.medical_specialtymultidetector CTJaccard indexMultidetector ctImaging Three-DimensionalSimilarity (network science)Multidetector Computed TomographyImage Processing Computer-AssistedMedicineHumansRadiology Nuclear Medicine and imagingIn patientSegmentationairway model reconstructionRobin SequencePierre Robin sequenceAnatomy Cross-SectionalPierre Robin Syndromebusiness.industryairways segmentationInfantGeneral MedicineOriginal ArticlesOrgan SizePIERRE ROBIN SEQUENCE MULTIDETECTOR CT3D renderingAirway ObstructionRegion growingCase-Control StudiesPharynxFemaleNeurology (clinical)LarynxAirwaybusinessNuclear medicineregion growing
researchProduct

Three-dimensional parametric modeling of bicuspid aortopathy and comparison with computational flow predictions

2016

Bicuspid aortic valve (BAV)-associated ascending aneurysmal aortopathy (namely “bicuspid aortopathy”) is a heterogeneous disease making surgeon predictions particularly challenging. Computational flow analysis can be used to evaluate the BAV-related hemodynamic disturbances, which likely lead to aneurysm enlargement and progression. However, the anatomic reconstruction process is time consuming so that predicting hemodynamic and structural evolution by computational modeling is unfeasible in routine clinical practice. The aim of the study was to design and develop a parametric program for three-dimensional (3D) representations of aneurysmal aorta and different BAV phenotypes starting fr…

MalePatient-Specific ModelingBicuspid aortic valveComputed Tomography AngiographyHeart Valve DiseasesBiomedical EngineeringMedicine (miscellaneous)Bioengineering—Three-dimensional anatomic reconstructionElectrocardiographyImaging Three-DimensionalBicuspid Aortic Valve DiseaseSettore ING-IND/12 - Misure Meccaniche E TermicheHumans—Finite-element analysiProspective StudiesAortaAgedRetrospective Studies—Aortic failureHemodynamicsModels CardiovascularComputational BiologySettore ING-IND/34 - Bioingegneria IndustrialeMiddle AgedBiomaterialAortic Aneurysm—Ascending thoracic aortic aneurysmAortic ValveFemaleStress MechanicalSoftware
researchProduct

Adult to Adult Living Donor Liver Transplantation in Recipients with Low MELD: A Strategy Intended to Overcome Donor Shortage

2020

Recent series have demonstrated advantages of living donor over deceased donor liver transplantation, with particular benefit for those with low model for end-stage liver disease score. The logic underlying the transplantation of patients before they become too sick is intuitive. It reduces mortality and drop outs from the waiting list and makes transplant surgery less demanding. Those principles have to be balanced with donor safety and transplant benefit for the recipient avoiding early, futile transplantation. The authors report a case of adult to adult right lobe living donor liver transplantation performed for a recipient affected by primary biliary cirrhosis with MELD score of 15, in …

MalePhysiologymedicine.medical_treatmentLiver transplantationSeverity of Illness IndexLiver diseasePostoperative Complications0302 clinical medicinePrimary biliary cirrhosisTransplant surgeryLiving DonorsLiver Transplantation.Liver resectionLiver Cirrhosis BiliaryGastroenterologyCone-Beam Computed TomographyMiddle AgedTreatment Outcomesurgical procedures operativeItalyLiver030220 oncology & carcinogenesisFemaleRisk Adjustment030211 gastroenterology & hepatologyLiving donor liver transplantationHumanAdultmedicine.medical_specialtyTissue and Organ ProcurementClinical Decision-MakingTime-to-TreatmentEnd Stage Liver Disease03 medical and health sciencesInternal medicineSeverity of illnessmedicineHepatectomyHumansIntensive care medicineLiver transplantationbusiness.industryLiving donor liver transplantationHepatologymedicine.diseasePleural EffusionTransplantationSurgeryPostoperative Complicationbusiness
researchProduct