Search results for "computer.software_genre"
showing 10 items of 3858 documents
MetNet: A two-level approach to reconstructing and comparing metabolic networks
2021
Metabolic pathway comparison and interaction between different species can detect important information for drug engineering and medical science. In the literature, proposals for reconstructing and comparing metabolic networks present two main problems: network reconstruction requires usually human intervention to integrate information from different sources and, in metabolic comparison, the size of the networks leads to a challenging computational problem. We propose to automatically reconstruct a metabolic network on the basis of KEGG database information. Our proposal relies on a two-level representation of the huge metabolic network: the first level is graph-based and depicts pathways a…
Detection, tracking and event localization of jet stream features in 4-D atmospheric data
2012
We introduce a novel algorithm for the efficient detection and tracking of features in spatiotemporal atmospheric data, as well as for the precise localization of the occurring genesis, lysis, merging and splitting events. The algorithm works on data given on a four-dimensional structured grid. Feature selection and clustering are based on adjustable local and global criteria, feature tracking is predominantly based on spatial overlaps of the feature's full volumes. The resulting 3-D features and the identified correspondences between features of consecutive time steps are represented as the nodes and edges of a directed acyclic graph, the event graph. Merging and splitting events appear in…
Lists of Spanish sentences with equivalent predictability, phonetic content, length, and frequency of the last word.
2010
This paper presents a pool of Spanish sentences designed for use in cognitive research and speech processing in circumstances in which the effects of context are relevant. These lists of sentences are divided into six lists of 25 equivalent high-predictability sentences and six lists of 25 low-predictability sentences according to the extent to which the last word can be predicted by the preceding context. These lists were also equivalent in phonetic content, length and frequency of the last word. These lists are intended for use in psycholinguistic research with Spanish-speaking listeners.
IntentStreams
2015
The user's understanding of information needs and the information available in the data collection can evolve during an exploratory search session. Search systems tailored for well-defined narrow search tasks may be suboptimal for exploratory search where the user can sequentially refine the expressions of her information needs and explore alternative search directions. A major challenge for exploratory search systems design is how to support such behavior and expose the user to relevant yet novel information that can be difficult to discover by using conventional query formulation techniques. We introduce IntentStreams, a system for exploratory search that provides interactive query refine…
A Machine Learning-Based Prediction Platform for P-Glycoprotein Modulators and Its Validation by Molecular Docking
2019
P-glycoprotein (P-gp) is an important determinant of multidrug resistance (MDR) because its overexpression is associated with increased efflux of various established chemotherapy drugs in many clinically resistant and refractory tumors. This leads to insufficient therapeutic targeting of tumor populations, representing a major drawback of cancer chemotherapy. Therefore, P-gp is a target for pharmacological inhibitors to overcome MDR. In the present study, we utilized machine learning strategies to establish a model for P-gp modulators to predict whether a given compound would behave as substrate or inhibitor of P-gp. Random forest feature selection algorithm-based leave-one-out random sampl…
Kernel-Based Framework for Multitemporal and Multisource Remote Sensing Data Classification and Change Detection
2008
The multitemporal classification of remote sensing images is a challenging problem, in which the efficient combination of different sources of information (e.g., temporal, contextual, or multisensor) can improve the results. In this paper, we present a general framework based on kernel methods for the integration of heterogeneous sources of information. Using the theoretical principles in this framework, three main contributions are presented. First, a novel family of kernel-based methods for multitemporal classification of remote sensing images is presented. The second contribution is the development of nonlinear kernel classifiers for the well-known difference and ratioing change detectio…
Characteristics and Measures for Mobile-Masquerader Detection
2006
Personal mobile devices, as mobile phones, smartphones, and communicators can be easily lost or stolen. Due to the functional abilities of these devices, their use by an unintended person may result in a severe security incident concerning private or corporate data and services. Organizations develop their security policy and mobilize preventive techniques against unauthorized use. Current solutions, however, are still breakable and there still exists strong need for means to detect user substitution when it happens. A crucial issue in designing such means is to define what measures to monitor.
A Linguistic Model in Component Oriented Programming
2016
Abstract It is a fact that the component-oriented programming, well organized, can bring a large increase in efficiency in the development of large software systems. This paper proposes a model for building software systems by assembling components that can operate independently of each other. The model is based on a computing environment that runs parallel and distributed applications. This paper introduces concepts as: abstract aggregation scheme and aggregation application. Basically, an aggregation application is an application that is obtained by combining corresponding components. In our model an aggregation application is a word in a language.
Optimal Filter Estimation for Lucas-Kanade Optical Flow
2012
Optical flow algorithms offer a way to estimate motion from a sequence of images. The computation of optical flow plays a key-role in several computer vision applications, including motion detection and segmentation, frame interpolation, three-dimensional scene reconstruction, robot navigation and video compression. In the case of gradient based optical flow implementation, the pre-filtering step plays a vital role, not only for accurate computation of optical flow, but also for the improvement of performance. Generally, in optical flow computation, filtering is used at the initial level on original input images and afterwards, the images are resized. In this paper, we propose an image filt…
CRISPR sequences are sometimes erroneously translated and can contaminate public databases with spurious proteins containing spaced repeats
2020
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